Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes

Research output: Contribution to journalJournal articleResearchpeer-review

Elza Muscelli, Arturo Casolaro, Amalia Gastaldelli, Andrea Mari, Giuseppe Seghieri, Brenno Astiarraga, Yu Chen, Maria Alba, Jens Juul Holst, Ele Ferrannini

Dipeptidyl peptidase IV (DPP-4) inhibitors improve glycemic control in patients with type 2 diabetes. The underlying mechanisms (incretin effect, β-cell function, endogenous glucose production) are not well known.
Original languageEnglish
JournalJournal of Clinical Endocrinology and Metabolism
Volume97
Issue number8
Pages (from-to)2818-26
Number of pages9
ISSN0021-972X
DOIs
Publication statusPublished - Aug 2012

    Research areas

  • Adult, Aged, Blood Glucose, Diabetes Mellitus, Type 2, Double-Blind Method, Female, Glucagon, Glucagon-Like Peptide 1, Humans, Hypoglycemic Agents, Insulin-Secreting Cells, Male, Middle Aged, Pyrazines, Triazoles

ID: 45841132