Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model

Research output: Contribution to journalJournal articleResearchpeer-review

Jennifer L Barnes, Bolette Hartmann, Jens Juul Holst, Kelly A Tappenden

Butyrate has been shown to stimulate intestinal adaptation when added to parenteral nutrition (PN) following small bowel resection but is not available in current PN formulations. The authors hypothesized that pre- and probiotic administration may be a clinically feasible method to administer butyrate and stimulate intestinal adaptation.
Original languageEnglish
JournalJournal of Parenteral and Enteral Nutrition
Volume36
Issue number5
Pages (from-to)524-37
Number of pages14
ISSN0148-6071
DOIs
Publication statusPublished - Sep 2012

    Research areas

  • Adaptation, Physiological, Animals, Animals, Newborn, Apoptosis, Butyrates, Cell Differentiation, Cell Proliferation, DNA Fragmentation, Dietary Supplements, Epithelial Cells, Glucagon-Like Peptide 2, Ileum, Intestinal Mucosa, Intestines, Lactobacillus rhamnosus, Oligosaccharides, Parenteral Nutrition, Prebiotics, Probiotics, Swine, Synbiotics

ID: 45841105