Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats

Research output: Contribution to journalJournal articleResearch

Anders Bue Klein, P Flagstad, P E G Kristjansen, F F Johansen, U Englund

Disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants.
Original languageEnglish
JournalActa Neurologica Scandinavica
Issue number2
Pages (from-to)94-100
Number of pages7
Publication statusPublished - Feb 2008

    Research areas

  • Animals, Behavior, Animal, Bromodeoxyuridine, Cell Count, Cell Proliferation, Dentate Gyrus, Drug Administration Schedule, Feeding Behavior, Fluoxetine, Ki-67 Antigen, Male, Microtubule-Associated Proteins, Neurons, Neuropeptides, Rats, Rats, Wistar, Reaction Time, Serotonin Uptake Inhibitors

ID: 105720050