IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC

Research output: PatentResearch

Claus Selch Larsen (Inventor), Susan Weng Larsen (Inventor), Mette Agergaard Thing (Inventor), Jesper Langgaard Kristensen (Inventor), HENRIK JENSEN, (Inventor), JESPER ØSTERGAARD, (Inventor)

The present invention relates to a compound of formula (I): wherein R1is R3-IPU and R2 is the acyloxy residue of diclofenac, and specified by the following structures: (II), (III) wherein OH-R3-IPU is selected from (IV) and R4 and R5 may be the same or different selected from H and CH3 and salts, solvates and hydrates thereof. The compounds are used for the treatment of pain such as postoperative pain following arthroscopic surgery.

Original languageEnglish
IPCA61P 29/ 00 A I
Patent numberWO2016066612
CountryDenmark
Priority date28/10/2014
Priority numberDK20140070657
Publication statusPublished - 6 May 2016

ID: 171123912