Growth Pattern of Atherosclerotic Calcifications

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Lene Lillemark Larsen, Melanie Ganz, Erik Dam, Naga Dandu, Mads Nielsen

We present a novel method to analyze the growth of abdominal atherosclerotic plaques based on x-ray projections. The growth analysis can aid progression monitoring in clinical trials and in population screening programs. Our results are based on a longitudinal study over 8.5 years. The annotations of the calcifications are matched longitudinally using thin plate spline registration and area overlap calculations.

The growth of the calcifications is measured by the distribution of the geometry statistics of the calcifications.

The method was evaluated on 135 subjects with a total number of 611 calcifications. Our results show, for instance longitudinal growth of calcifications with a mean of 2.53 mm ($\pm$ 1.95) in the blood flow direction and correlations with pathologically related biomarkers.

Original languageEnglish
Title of host publicationCVII '08 : Second International Workshop on Computer vision for intracardiac and intravascular imaging, held in New York, USA, September 10, 2008 in conjunction with the 11th MICCAI conference
PublisherSabancí Üniversítesí. 34956 Tuzla, Istanbul
Publication date2008
Pages63-70
Publication statusPublished - 2008
EventMedical Image Computing and Computer-Assisted Intervention (MICCAI), 2th Workshop on Computer Vision for Intravascular and IntraCardiac Imaging (CVII), 2008 - New York, United States
Duration: 10 Sep 200810 Sep 2008
Conference number: 2

Conference

ConferenceMedical Image Computing and Computer-Assisted Intervention (MICCAI), 2th Workshop on Computer Vision for Intravascular and IntraCardiac Imaging (CVII), 2008
Nummer2
LandUnited States
ByNew York
Periode10/09/200810/09/2008

ID: 9701414