Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype

Research output: Contribution to journalJournal articleResearchpeer-review

Sofia Inez Iqbal Kring, Lesli Hingstrup Larsen, Claus Holst, Søren Toubro, Torben Hansen, Arne Astrup, Oluf Pedersen, Thorkild I A Sørensen

In previous studies of associations of variants in the genes UCP2, UCP3, PPARG2, CART, GRL, MC4R, MKKS, SHP, GHRL, and MCHR1 with obesity, we have used a case-control approach with cases defined by a threshold for BMI. In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene polymorphisms in these ten genes in the same cohort.
Original languageEnglish
JournalObesity Facts
Volume1
Issue number3
Pages (from-to)138-145
Number of pages8
ISSN1662-4025
DOIs
Publication statusPublished - 2008

    Research areas

  • Adult, Alleles, Body Fat Distribution, Body Mass Index, Case-Control Studies, Cohort Studies, Denmark, Follow-Up Studies, Genetic Association Studies, Humans, Ion Channels, Logistic Models, Male, Middle Aged, Mitochondrial Proteins, Obesity, Phenotype, Polymorphism, Genetic, Receptors, Cytoplasmic and Nuclear, Receptors, Somatostatin, Waist Circumference

ID: 8113290