Genome-wide association studies of human adiposity: Zooming in on synapses.

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Genome-wide association studies of human adiposity: Zooming in on synapses. / Sandholt, Camilla H.; Grarup, Niels; Pedersen, Oluf; Hansen, Torben.

In: Molecular and Cellular Endocrinology, Vol. 418, No. Part 2, 2015, p. 90-100.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Sandholt, CH, Grarup, N, Pedersen, O & Hansen, T 2015, 'Genome-wide association studies of human adiposity: Zooming in on synapses.', Molecular and Cellular Endocrinology, vol. 418, no. Part 2, pp. 90-100. https://doi.org/10.1016/j.mce.2015.09.029

APA

Sandholt, C. H., Grarup, N., Pedersen, O., & Hansen, T. (2015). Genome-wide association studies of human adiposity: Zooming in on synapses. Molecular and Cellular Endocrinology, 418(Part 2), 90-100. https://doi.org/10.1016/j.mce.2015.09.029

Vancouver

Sandholt CH, Grarup N, Pedersen O, Hansen T. Genome-wide association studies of human adiposity: Zooming in on synapses. Molecular and Cellular Endocrinology. 2015;418(Part 2):90-100. https://doi.org/10.1016/j.mce.2015.09.029

Author

Sandholt, Camilla H. ; Grarup, Niels ; Pedersen, Oluf ; Hansen, Torben. / Genome-wide association studies of human adiposity: Zooming in on synapses. In: Molecular and Cellular Endocrinology. 2015 ; Vol. 418, No. Part 2. pp. 90-100.

Bibtex

@article{1b5205dd51bc401f8ad750e0899b0f65,
title = "Genome-wide association studies of human adiposity: Zooming in on synapses.",
abstract = "The decade anniversary for genome-wide assocn. studies (GWAS) is approaching, and this exptl. approach has commenced a deeper understanding of the genetics underlying complex diseases. In obesity genetics the GIANT (Genetic Investigation of ANthropometric Traits) consortium has played a crucial role, recently with two comprehensive meta-analyses, one focusing on general obesity, analyzing body-mass index (BMI) and the other on fat distribution, focusing on waist-hip ratio adjusted for BMI. With the in silico methods applied in these two studies as the pivot, this review looks into some of the biol. knowledge, beginning to emerge from the intricate genomic background behind the genetic determinants of human adiposity. These include synaptic dysfunction, where GWAS pinpoint potential new mechanisms in pathways already known to be linked with obesity.",
author = "Sandholt, {Camilla H.} and Niels Grarup and Oluf Pedersen and Torben. Hansen",
note = "M1 - Copyright (C) 2015 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 2015:1879448(Journal; Online Computer File)",
year = "2015",
doi = "10.1016/j.mce.2015.09.029",
language = "English",
volume = "418",
pages = "90--100",
journal = "Molecular and Cellular Endocrinology",
issn = "0303-7207",
publisher = "Elsevier Ireland Ltd",
number = "Part 2",

}

RIS

TY - JOUR

T1 - Genome-wide association studies of human adiposity: Zooming in on synapses.

AU - Sandholt, Camilla H.

AU - Grarup, Niels

AU - Pedersen, Oluf

AU - Hansen, Torben.

N1 - M1 - Copyright (C) 2015 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 2015:1879448(Journal; Online Computer File)

PY - 2015

Y1 - 2015

N2 - The decade anniversary for genome-wide assocn. studies (GWAS) is approaching, and this exptl. approach has commenced a deeper understanding of the genetics underlying complex diseases. In obesity genetics the GIANT (Genetic Investigation of ANthropometric Traits) consortium has played a crucial role, recently with two comprehensive meta-analyses, one focusing on general obesity, analyzing body-mass index (BMI) and the other on fat distribution, focusing on waist-hip ratio adjusted for BMI. With the in silico methods applied in these two studies as the pivot, this review looks into some of the biol. knowledge, beginning to emerge from the intricate genomic background behind the genetic determinants of human adiposity. These include synaptic dysfunction, where GWAS pinpoint potential new mechanisms in pathways already known to be linked with obesity.

AB - The decade anniversary for genome-wide assocn. studies (GWAS) is approaching, and this exptl. approach has commenced a deeper understanding of the genetics underlying complex diseases. In obesity genetics the GIANT (Genetic Investigation of ANthropometric Traits) consortium has played a crucial role, recently with two comprehensive meta-analyses, one focusing on general obesity, analyzing body-mass index (BMI) and the other on fat distribution, focusing on waist-hip ratio adjusted for BMI. With the in silico methods applied in these two studies as the pivot, this review looks into some of the biol. knowledge, beginning to emerge from the intricate genomic background behind the genetic determinants of human adiposity. These include synaptic dysfunction, where GWAS pinpoint potential new mechanisms in pathways already known to be linked with obesity.

U2 - 10.1016/j.mce.2015.09.029

DO - 10.1016/j.mce.2015.09.029

M3 - Journal article

VL - 418

SP - 90

EP - 100

JO - Molecular and Cellular Endocrinology

JF - Molecular and Cellular Endocrinology

SN - 0303-7207

IS - Part 2

ER -

ID: 150703170