Fighting cancer using an oncofetal glycosaminoglycan-binding protein from malaria parasites

Research output: Contribution to journalJournal articleResearchpeer-review

Mette Agerbæk, Sara Bang-Christensen, Ali Salanti

Malaria research has led to the discovery of oncofetal chondroitin sulfate, which appears to be shared between placental trophoblasts and cancer cells and can be detected by the evolutionary refined malaria protein VAR2CSA. Interestingly, using recombinant VAR2CSA to target oncofetal chondroitin sulfate shows promise for novel cancer diagnostics and therapeutics.

Original languageEnglish
JournalTrends in Parasitology
Volume35
Issue number3
Pages (from-to)178-181
ISSN1471-4922
DOIs
Publication statusPublished - 2019

    Research areas

  • cancer, oncofetal chondroitin sulfate, placental malaria, VAR2CSA

ID: 212857987