Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits

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Anette Marianne Prior Gjesing, Claus Thorn Ekstrøm, Hans Rudolf Lytchoff Eiberg, S.A. Urhammer, Jens Juul Holst, Oluf Pedersen, Teis Hansen

Heritability estimates have shown a varying degree of genetic contribution to traits related to type 2 diabetes. Therefore, the objective of this study was to investigate the familiality of fasting and stimulated measures of plasma glucose, serum insulin, serum C-peptide, plasma glucose-dependent insulinotropic polypeptide (GIP) and plasma glucagon-like peptide-1 (GLP-1) among non-diabetic relatives of Danish type 2 diabetic patients.
Original languageEnglish
JournalDiabetologia
Volume55
Issue number5
Pages (from-to)1338-1345
Number of pages8
ISSN0012-186X
DOIs
Publication statusPublished - 2012

ID: 38474651