Endothelial glycocalyx: shedding light on malaria pathogenesis

Research output: Contribution to journalJournal articleResearchpeer-review

Casper Hempel, Erica M Pasini, Jørgen A L Kurtzhals

Malaria is estimated to kill 438 000 people annually, mostly due to severe malaria, which is closely associated with microcirculatory vasculopathy, although its pathogenesis remains incompletely understood. Here, we propose that the largely ignored glycocalyx of the vascular endothelium plays an important role in facilitating the pathogenesis of severe malaria.

Original languageEnglish
JournalTrends in Molecular Medicine
Volume22
Issue number6
Pages (from-to)453-457
Number of pages5
ISSN1471-4914
DOIs
Publication statusPublished - Jun 2016

ID: 162190707