Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

Research output: Contribution to journalJournal articleResearchpeer-review

Meena Asmar, Michael Bache, Filip K Knop, Sten Madsbad, Jens Juul Holst

Amylin, cosecreted with insulin, has like glucagon-like peptide-1 (GLP-1) been reported to inhibit glucagon secretion, delay gastric emptying, and reduce appetite and food intake. We investigated whether the effects of GLP-1 on gastric emptying, appetite, and food intake are mediated directly or indirectly via release of amylin.
Original languageEnglish
JournalThe Journal of clinical endocrinology and metabolism
Issue number5
Pages (from-to)2367-75
Number of pages9
Publication statusPublished - 1 May 2010

    Research areas

  • Adult, Amyloid, Appetite, Body Mass Index, C-Peptide, Cross-Over Studies, Diabetes Mellitus, Type 1, Gastric Emptying, Glucagon, Glucagon-Like Peptide 1, Hemoglobin A, Glycosylated, Humans, Hypoglycemic Agents, Insulin, Islet Amyloid Polypeptide, Reference Values, Single-Blind Method

ID: 33940040