Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

Research output: Contribution to journalJournal articleResearchpeer-review

P T Schmidt, B Hartmann, S Bregenholt, Jens Juul Holst, Mogens Helweg Claesson

Glucagon-like peptide 2 (GLP-2) is produced in endocrine L-cells of the intestinal mucosa. Recently, GLP-2 was found to stimulate intestinal mucosal growth. Our objective was to study the content of GLP-2 in the large intestine in a murine model of T-cell-induced inflammatory bowel disease.
Original languageEnglish
JournalScandinavian Journal of Gastroenterology
Volume35
Issue number5
Pages (from-to)522-7
Number of pages6
ISSN0036-5521
Publication statusPublished - 1 May 2000

    Research areas

  • Animals, CD4-Positive T-Lymphocytes, Colon, Disease Models, Animal, Glucagon, Glucagon-Like Peptide 2, Glucagon-Like Peptides, Growth Substances, Inflammatory Bowel Diseases, Mice, Mice, SCID, Peptide Fragments

ID: 183966