Decreased delayed hypersensitivity to tuberculin demonstrated in experimental leptospirosis in guinea pigs.

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H Colding, K S Johansen, M W Bentzon

Skin reactivity to tuberculin has been studied during the course of experimental leptospirosis in guinea pigs. A depression of the delayed hypersensitivity to tuberculin was demonstrated in the infected animals. The depression was most pronounced when icterus had developed. The depression was not correlated with the amount of infectious units administered or with the demonstration of live leptospirae in the peritoneal cavity. In the infected animals there was no correlation between the initial and the final skin tests which is in contrast to findings in the control group.
Original languageEnglish
JournalActa pathologica et microbiologica Scandinavica. Section C, Immunology
Volume84
Issue number3
Pages (from-to)255-60
Number of pages5
ISSN0304-1328
Publication statusPublished - 1976

Bibliographical note

Keywords: Animals; Guinea Pigs; Hypersensitivity, Delayed; Leptospirosis; Male; Pilot Projects; Tuberculin Test

ID: 8670329