Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes

Research output: Contribution to journalJournal articleResearchpeer-review

Lena Sønder Snogdal, Mette Wod, Niels Grarup, M Vestmar, Thomas Hempel Sparsø, T Jørgensen, Torsten Lauritzen, Henning Beck-Nielsen, J E Henriksen, Oluf Pedersen, Torben Hansen, K Højlund

There is substantial evidence that mitochondrial dysfunction is linked to insulin resistance and is present in several tissues relevant to the pathogenesis of type 2 diabetes. Here, we examined whether common variation in genes involved in oxidative phosphorylation (OxPhos) contributes to type 2 diabetes susceptibility or influences diabetes-related metabolic traits.
Original languageEnglish
JournalDiabetologia
Volume55
Issue number2
Pages (from-to)340-8
Number of pages9
ISSN0012-186X
DOIs
Publication statusPublished - 2012

ID: 40208768