Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and Tat(47-57) through well-differentiated epithelial models

Research output: Contribution to journalJournal articleResearchpeer-review

Rachel Tréhin, Ulrike Krauss, Annette G Beck-Sickinger, Hans P Merkle, Hanne Mørck Nielsen

To investigate whether cell penetrating peptides (CPP) derived from human calcitonin (hCT) possess, in addition to cellular uptake, the capacity to deliver their cargo through epithelial barriers.
Original languageEnglish
JournalPharmaceutical Research
Issue number7
Pages (from-to)1248-56
Number of pages9
Publication statusPublished - 2004

    Research areas

  • Animals, Calcitonin, Carrier Proteins, Cell Line, Cell Membrane Permeability, Chromatography, High Pressure Liquid, Epithelial Cells, Fluoresceins, Fluorescent Dyes, Gene Products, tat, Humans, Microscopy, Confocal, Peptide Fragments

ID: 43890583