Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings. / Madsen, Mette Flethøj; Kanters, Jørgen K.; Pedersen, Philip Juul; Haugaard, Maria Mathilde; Carstensen, Helena; Olsen, Lisbeth Høier; Buhl, Rikke.

In: BMC Veterinary Research, Vol. 12, 266, 28.11.2016.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Madsen, MF, Kanters, JK, Pedersen, PJ, Haugaard, MM, Carstensen, H, Olsen, LH & Buhl, R 2016, 'Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings', BMC Veterinary Research, vol. 12, 266. https://doi.org/10.1186/s12917-016-0894-2

APA

Madsen, M. F., Kanters, J. K., Pedersen, P. J., Haugaard, M. M., Carstensen, H., Olsen, L. H., & Buhl, R. (2016). Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings. BMC Veterinary Research, 12, [266]. https://doi.org/10.1186/s12917-016-0894-2

Vancouver

Madsen MF, Kanters JK, Pedersen PJ, Haugaard MM, Carstensen H, Olsen LH et al. Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings. BMC Veterinary Research. 2016 Nov 28;12. 266. https://doi.org/10.1186/s12917-016-0894-2

Author

Madsen, Mette Flethøj ; Kanters, Jørgen K. ; Pedersen, Philip Juul ; Haugaard, Maria Mathilde ; Carstensen, Helena ; Olsen, Lisbeth Høier ; Buhl, Rikke. / Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings. In: BMC Veterinary Research. 2016 ; Vol. 12.

Bibtex

@article{bd56917e1a0f4ecf98ad52237a1b1dca,
title = "Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings",
abstract = "Background: Although premature beats are a matter of concern in horses, the interpretation of equine ECG recordings is complicated by a lack of standardized analysis criteria and a limited knowledge of the normal beat-to-beat variation of equine cardiac rhythm. The purpose of this study was to determine the appropriate threshold levels of maximum acceptable deviation of RR intervals in equine ECG analysis, and to evaluate a novel two-step timing algorithm by quantifying the frequency of arrhythmias in a cohort of healthy adult endurance horses.Results: Beat-to-beat variation differed considerably with heart rate (HR), and an adaptable model consisting of three different HR ranges with separate threshold levels of maximum acceptable RR deviation was consequently defined. For resting HRs <60 beats/min (bpm) the threshold level of RR deviation was set at 20{\%}, for HRs in the intermediate range between 60 and 100 bpm the threshold was 10{\%}, and for exercising HRs >100 bpm, the threshold level was 4{\%}. Supraventricular premature beats represented the most prevalent arrhythmia category with varying frequencies in seven horses at rest (median 7, range 2–86) and six horses during exercise (median 2, range 1–24).Conclusions: Beat-to-beat variation of equine cardiac rhythm varies according to HR, and threshold levels in equine ECG analysis should be adjusted accordingly. Standardization of the analysis criteria will enable comparisons of studies and follow-up examinations of patients. A small number of supraventricular premature beats appears to be a normal finding in endurance horses. Further studies are required to validate the findings and determine the clinical significance of premature beats in horses.",
keywords = "ECG analysis, Heart rate variability, Arrhythmias, Endurance horses",
author = "Madsen, {Mette Fleth{\o}j} and Kanters, {J{\o}rgen K.} and Pedersen, {Philip Juul} and Haugaard, {Maria Mathilde} and Helena Carstensen and Olsen, {Lisbeth H{\o}ier} and Rikke Buhl",
year = "2016",
month = "11",
day = "28",
doi = "10.1186/s12917-016-0894-2",
language = "English",
volume = "12",
journal = "B M C Veterinary Research",
issn = "1746-6148",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

AU - Madsen, Mette Flethøj

AU - Kanters, Jørgen K.

AU - Pedersen, Philip Juul

AU - Haugaard, Maria Mathilde

AU - Carstensen, Helena

AU - Olsen, Lisbeth Høier

AU - Buhl, Rikke

PY - 2016/11/28

Y1 - 2016/11/28

N2 - Background: Although premature beats are a matter of concern in horses, the interpretation of equine ECG recordings is complicated by a lack of standardized analysis criteria and a limited knowledge of the normal beat-to-beat variation of equine cardiac rhythm. The purpose of this study was to determine the appropriate threshold levels of maximum acceptable deviation of RR intervals in equine ECG analysis, and to evaluate a novel two-step timing algorithm by quantifying the frequency of arrhythmias in a cohort of healthy adult endurance horses.Results: Beat-to-beat variation differed considerably with heart rate (HR), and an adaptable model consisting of three different HR ranges with separate threshold levels of maximum acceptable RR deviation was consequently defined. For resting HRs <60 beats/min (bpm) the threshold level of RR deviation was set at 20%, for HRs in the intermediate range between 60 and 100 bpm the threshold was 10%, and for exercising HRs >100 bpm, the threshold level was 4%. Supraventricular premature beats represented the most prevalent arrhythmia category with varying frequencies in seven horses at rest (median 7, range 2–86) and six horses during exercise (median 2, range 1–24).Conclusions: Beat-to-beat variation of equine cardiac rhythm varies according to HR, and threshold levels in equine ECG analysis should be adjusted accordingly. Standardization of the analysis criteria will enable comparisons of studies and follow-up examinations of patients. A small number of supraventricular premature beats appears to be a normal finding in endurance horses. Further studies are required to validate the findings and determine the clinical significance of premature beats in horses.

AB - Background: Although premature beats are a matter of concern in horses, the interpretation of equine ECG recordings is complicated by a lack of standardized analysis criteria and a limited knowledge of the normal beat-to-beat variation of equine cardiac rhythm. The purpose of this study was to determine the appropriate threshold levels of maximum acceptable deviation of RR intervals in equine ECG analysis, and to evaluate a novel two-step timing algorithm by quantifying the frequency of arrhythmias in a cohort of healthy adult endurance horses.Results: Beat-to-beat variation differed considerably with heart rate (HR), and an adaptable model consisting of three different HR ranges with separate threshold levels of maximum acceptable RR deviation was consequently defined. For resting HRs <60 beats/min (bpm) the threshold level of RR deviation was set at 20%, for HRs in the intermediate range between 60 and 100 bpm the threshold was 10%, and for exercising HRs >100 bpm, the threshold level was 4%. Supraventricular premature beats represented the most prevalent arrhythmia category with varying frequencies in seven horses at rest (median 7, range 2–86) and six horses during exercise (median 2, range 1–24).Conclusions: Beat-to-beat variation of equine cardiac rhythm varies according to HR, and threshold levels in equine ECG analysis should be adjusted accordingly. Standardization of the analysis criteria will enable comparisons of studies and follow-up examinations of patients. A small number of supraventricular premature beats appears to be a normal finding in endurance horses. Further studies are required to validate the findings and determine the clinical significance of premature beats in horses.

KW - ECG analysis

KW - Heart rate variability

KW - Arrhythmias

KW - Endurance horses

U2 - 10.1186/s12917-016-0894-2

DO - 10.1186/s12917-016-0894-2

M3 - Journal article

VL - 12

JO - B M C Veterinary Research

JF - B M C Veterinary Research

SN - 1746-6148

M1 - 266

ER -

ID: 170214379