Amyloid-related biomarkers and axonal damage proteins in parkinsonian syndromes

Research output: Contribution to journalJournal articleResearchpeer-review

Sara Bech, Lena E Hjermind, Lisette Salvesen, Jørgen E Nielsen, Niels H H Heegaard, Henrik L Jørgensen, Lars Rosengren, Kaj Blennow, Henrik Zetterberg, Kristian Winge

Clinical differentiation between parkinsonian syndromes (PS) remains a challenge despite well-established clinical diagnostic criteria. Specific diagnostic biomarkers have yet to be identified, though in recent years, studies have been published on the aid of certain brain related proteins (BRP) in the diagnosing of PS. We investigated the levels of the light subunit of neurofilament triplet protein (NF-L), total tau and phosphorylated tau, amyloid-ß(1-42), and the soluble a- and ß-cleaved fragments of amyloid precursor proteins in a cohort of patients with various PS.
Original languageEnglish
JournalParkinsonism & Related Disorders
Volume18
Issue number1
Pages (from-to)69-72
Number of pages4
ISSN1353-8020
DOIs
Publication statusPublished - 2012

ID: 38425969