Alpha-fetoprotein and human chorionic gonadotropin in a patient with a primary intracranial germ cell tumor.

Research output: Contribution to journalJournal articleResearchpeer-review

B Nørgaard-Pedersen, J Lindholm, R Albrechtsen, J Arends, N H Diemer, J Riishede

A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluorescence staining of the tumor tissue a slight staining for AFP was localized to the endodermal vesicles, whereas a more intensive staining for hCG could be identified in the giant cells.
Original languageEnglish
Issue number6
Pages (from-to)2315-20
Number of pages5
Publication statusPublished - 1978
Externally publishedYes

Bibliographical note

Keywords: Adolescent; Brain Neoplasms; Chorionic Gonadotropin; Dysgerminoma; Fluorescent Antibody Technique; Humans; Male; alpha-Fetoproteins

ID: 5237396