Afferent Endocrine Control of Eating

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Wolfgang Langhans, Jens Juul Holst

The afferent endocrine factors that control eating can be separated into different categories. One obvious categorization is by the time course of their effects, with long-term factors that signal adiposity and short-term factors that operate within the time frame of single meals. The second obvious categorization is by the origin of the endocrine signalling molecules. The level of knowledge concerning the physiological mechanisms and relevance of the hormones that are implicated in the control of eating is clearly different. With the accumulating knowledge about the hormones' actions, various criteria have been developed for when the effect of a hormone can be considered 'physiologic'. This chapter treats the hormones separately and categorizes them by origin. It discusses ALL hormones that are implicated in eating control such as Gastrointestinal (GI) hormone and glucagon-like peptide-1, and focuses on particular examples. Finally, the chapter reviews some of the principal evidence supporting a role of leptin as an adiposity signal.

Original languageEnglish
Title of host publicationNeuroendocrinology of Appetite
EditorsSuzanne L. Dickson, Julian G. Mercer
Number of pages31
Publication date22 Aug 2016
ISBN (Print)9781118839324
ISBN (Electronic)9781118839317
Publication statusPublished - 22 Aug 2016

    Research areas

  • Afferent endocrine factors, Gastrointestinal hormone, Glucagon-like peptide-1, Overeating control, Peptide tyrosine tyrosine

ID: 178844391