β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?
Research output: Contribution to journal › Journal article › Research › peer-review
Jakob G Knudsen, Patrik Rorsman
Type 2 diabetes is a progressive disorder, but exactly how the progression occurs remains unknown. In this issue of Cell Metabolism, Zhang et al. (2019) present evidence that diabetes, via hyperglycemia, leads to aberrant insertion of a mitochondrial ion channel in the plasma membrane, rendering it leaky to key intracellular signaling molecules with resultant suppression of insulin secretion.
|Number of pages||2|
|Publication status||Published - 8 Jan 2019|