β Cell Dysfunction in Type 2 Diabetes: Drained of Energy?

Research output: Contribution to journalJournal articleResearchpeer-review

Jakob G Knudsen, Patrik Rorsman

Type 2 diabetes is a progressive disorder, but exactly how the progression occurs remains unknown. In this issue of Cell Metabolism, Zhang et al. (2019) present evidence that diabetes, via hyperglycemia, leads to aberrant insertion of a mitochondrial ion channel in the plasma membrane, rendering it leaky to key intracellular signaling molecules with resultant suppression of insulin secretion.

Original languageEnglish
JournalCell Metabolism
Volume29
Issue number1
Pages (from-to)1-2
Number of pages2
ISSN1550-4131
DOIs
Publication statusPublished - 8 Jan 2019

ID: 220850414