Thue W. Schwartz

Thue W. Schwartz

Professor

  • Schwartz Group

    Blegdamsvej 3B, 2200 København N, Maersk Tower, Building: 07-6-85

  • Nutrient and Metabolite Sensing

    Blegdamsvej 3B, Building: 07-6-85

    2200 København N

    Denmark


  1. 2006
  2. Published

    Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation. / Elling, Christian E; Frimurer, Thomas M; Gerlach, Lars-Ole; Jorgensen, Rasmus; Holst, Birgitte; Schwartz, Thue W.

    In: Journal of Biological Chemistry, Vol. 281, No. 25, 2006, p. 17337-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    GPR39 signaling is stimulated by zinc ions but not by obestatin. / Holst, Birgitte; Egerod, Kristoffer L; Schild, Enrico; Vickers, Steve P; Cheetham, Sharon; Gerlach, Lars-Ole; Storjohann, Laura; Stidsen, Carsten E; Jones, Rob; Beck-Sickinger, Annette G; Schwartz, Thue W.

    In: Endocrinology, Vol. 148, No. 1, 2006, p. 13-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor. / Holst, Birgitte; Lang, Manja; Brandt, Erik; Bach, Anders; Howard, Andrew; Frimurer, Thomas M; Beck-Sickinger, Annette; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 70, No. 3, 2006, p. 936-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Ghrelin receptor mutations--too little height and too much hunger. / Holst, Birgitte; Schwartz, Thue W.

    In: Journal of Clinical Investigation, Vol. 116, No. 3, 2006, p. 637-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR. / Nygaard, Rie; Nielbo, Steen; Schwartz, Thue W; Poulsen, Flemming M.

    In: Biochemistry, Vol. 45, No. 27, 2006, p. 8350-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    GluVII : 06 - a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors. / Rosenkilde, M.M.; Schwartz, T.W.

    In: Current Topics in Medicinal Chemistry, Vol. 6, No. 13, 2006, p. 1319-1333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI. / Rosenkilde, Mette M; Andersen, Michael B; Nygaard, Rie; Frimurer, Thomas M; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 71, No. 3, 2006, p. 930-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V. / Rosenkilde, Mette M; David, Ralf; Oerlecke, Ilka; Benned-Jensen, Tau; Geumann, Ulf; Beck-Sickinger, Anette G; Schwartz, Thue W.

    In: Molecular Pharmacology, Vol. 70, No. 6, 2006, p. 1892-901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors. / Rosenkilde, Mette M; Schwartz, Thue W.

    In: Current Topics in Medicinal Chemistry, Vol. 6, No. 13, 2006, p. 1319-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity. / Rosenkilde, Mette M; Benned-Jensen, Tau; Holst, Peter J; Kledal, Thomas N; Lüttichau, Hans R; Larsen, Jørgen K; Christensen, Jan P; Schwartz, Thue W; Andersen, Helene.

    In: Journal of Biological Chemistry, Vol. 281, No. 19, 2006, p. 13199-208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors. / Schwartz, Thue W; Holst, Birgitte.

    In: Journal of Receptors and Signal Transduction, Vol. 26, No. 1-2, 2006, p. 107-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular mechanism of 7TM receptor activation--a global toggle switch model. / Schwartz, Thue W; Frimurer, Thomas M; Holst, Birgitte; Rosenkilde, Mette M; Elling, Christian E.

    In: Annual Review of Pharmacology and Toxicology, Vol. 46, 2006, p. 481-519.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11601