Signe Lykke Nielsen

Signe Lykke Nielsen

bioanalyst


Publication year:
  1. 2016
  2. Published

    Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines. / Jandu, Haatisha; Aluzaité, Kristina; Fogh, Louise; Thrane, Sebastian Wingaard; Noer, Julie B; Proszek, Joanna; Nguyen Do, Khoa; Hansen, Stine Ninel; Damsgaard-Hansen, Britt; Nielsen, Signe Lykke; Stougaard, Magnus; Knudsen, Birgitta R.; Moreira, José; Hamerlik, Petra; Gajjar, Madhavsai; Smid, Marcel; Martens, John; Foekens, John; Pommier, Yves; Brünner, Nils; Rasmussen, Anne-Sofie Schrohl; Stenvang, Jan.

    In: B M C Cancer, Vol. 16, 34, 22.01.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification. / Tarpgaard, Line S.; Qvortrup, Camilla; Nygård, Sune Boris; Nielsen, Signe Lykke; Andersen, Diana R.; Jensen, Niels Frank; Stenvang, Jan; Detlefsen, Sönke; Brünner, Nils; Pfeiffer, Per.

    In: B M C Cancer, Vol. 16, 91, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer. / Nygård, Sune Boris; Vainer, Ben; Nielsen, Signe L; Bosman, Fred T; Tejpar, Sabine; Roth, Arnaud; Delorenzi, Mauro; Brunner, Nils; Budinska, Eva.

    In: Clinical Cancer Research, Vol. 22, No. 7, 2016, p. 1621-1631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2015
  6. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer. / Kümler, Iben; Balslev, Eva; Poulsen, Tim S.; Nielsen, Signe Lykke; Nygård, Sune Boris; Rømer, Maria Unni; Christensen, Ib Jarle; Høgdall, Estrid; Moreira, José; Nielsen, Dorte Lisbet; Brünner, Nils; Stenvang, Jan.

    In: International Journal of Cancer, Vol. 137, No. 8, 08.04.2015, p. 2000-2006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2014
  8. Published

    MYC translocation partner gene determines survival of patients with large B-cell lymphoma with MYC- or double-hit MYC/BCL2 translocations. / Pedersen, Mette Ø; Gang, Anne O; Poulsen, Tim S; Knudsen, Helle; Lauritzen, Anne F; Nielsen, Signe L; Klausen, Tobias W; Nørgaard, Peter.

    In: European Journal of Haematology, Vol. 92, No. 1, 01.2014, p. 42-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer. / Nygård, Sune Boris; Christensen, Ib Jarle; Nielsen, Signe Lykke; Nielsen, Hans Jørgen; Brünner, Nils; Spindler, Karen-Lise Garm.

    In: Scandinavian Journal of Gastroenterology, Vol. 49, No. 1, 2014, p. 84-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2013
  11. Published

    Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis. / Rømer, Maria Unni Koefoed; Nygård, Sune Boris; Christensen, Ib Jarle; Nielsen, Signe Lykke; Nielsen, Kirsten Vang; Müller, Sven; Smith, David Hersi; Vainer, Ben; Nielsen, Hans Jørgen; Brünner, Nils.

    In: Molecular Oncology, Vol. 7, No. 1, 2013, p. 101-111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Underpinning the repurposing of anthracyclines towards colorectal cancer : assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer. / Nygård, Sune Boris; Christensen, Ib Jarle; Smith, David Hersi; Nielsen, Signe Lykke; Jensen, Niels Frank; Nielsen, Hans Jørgen; Vainer, Ben; Brünner, Nils.

    In: Scandinavian Journal of Gastroenterology, Vol. 48, No. 12, 2013, p. 1436-1443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2012
  14. Published

    TOP1 gene copy number and TOP1/CEN-20 ratio in stage III colorectal cancer samples. / Rømer, Maria Unni Koefoed; Nygård, Sune Boris; Christensen, Ib Jarle; Hersi Smith, David; Vang Nielsen, Kirsten; Müller, Sven; Vainer, Ben; Nielsen, Hans Jørgen; Nielsen, Signe Lykke; Brunner, Nils.

    2012. Poster session presented at Dansk Selskab for Cancerforsknings årsmøde 2012, Ordrup, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  15. Published

    TOP1 gene copy numbers in colorectal cancer samples and cell lines and their association to in vitro drug sensitivity. / Rømer, Maria Unni; Jensen, Niels Frank; Nielsen, Signe Lykke; Müller, Sven; Nielsen, Kirsten Vang; Nielsen, Hans Jørgen; Brünner, Nils.

    In: Scandinavian Journal of Gastroenterology, Vol. 47, No. 1, 2012, p. 68-79.

    Research output: Contribution to journalJournal articleResearchpeer-review

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