Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2018
  2. Published

    Recovery of gut microbiota of healthy adults following antibiotic exposure. / Palleja, Albert; Mikkelsen, Kristian H; Forslund, Sofia K; Kashani, Alireza; Allin, Kristine H; Nielsen, Trine; Hansen, Tue H; Liang, Suisha; Feng, Qiang; Zhang, Chenchen; Pyl, Paul Theodor; Coelho, Luis Pedro; Yang, Huanming; Wang, Jian; Typas, Athanasios; Nielsen, Morten F.; Nielsen, Henrik Bjorn; Bork, Peer; Wang, Jun; Vilsbøll, Tina; Hansen, Torben; Knop, Filip K; Arumugam, Manimozhiyan; Pedersen, Oluf.

    In: Nature Microbiology, Vol. 3, No. 11, 11.2018, p. 1255-1265.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences. / Gæde, Joachim; Nielsen, Trine; Madsen, Mia L; Toft, Ulla; Jørgensen, Torben; Overvad, Kim; Tjønneland, Anne; Hansen, Torben; Allin, Kristine H; Pedersen, Oluf.

    In: Nutrition Journal, Vol. 17, No. 1, 91, 06.10.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population. / Grarup, Niels; Moltke, Ida; Andersen, Mette K.; Bjerregaard, Peter; Larsen, Christina V.L.; Dahl-Petersen, Inger K.; Jørsboe, Emil; Tiwari, Hemant K.; Hopkins, Scarlett E.; Wiener, Howard W.; Boyer, Bert B.; Linneberg, Allan; Pedersen, Oluf; Jørgensen, Marit E.; Albrechtsen, Anders; Hansen, Torben.

    In: Diabetologia, Vol. 61, No. 9, 09.2018, p. 2005–2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese. / Graae, Anne Sofie; Hollensted, Mette; Kloppenborg, Julie T.; Mahendran, Yuvaraj; Schnurr, Theresia M.; Appel, Emil Vincent R.; Rask, Johanne; Nielsen, Tenna R.H.; Johansen, Mia; Linneberg, Allan; Jørgensen, Marit E.; Grarup, Niels; Kadarmideen, Haja N.; Holst, Birgitte; Pedersen, Oluf; Holm, Jens-Christian; Hansen, Torben.

    In: Diabetologia, Vol. 61, No. 8, 08.2018, p. 1769-1779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. / Prins, Bram P; Mead, Timothy J; Brody, Jennifer A; Sveinbjornsson, Gardar; Ntalla, Ioanna; Bihlmeyer, Nathan A; van den Berg, Marten; Bork-Jensen, Jette; Cappellani, Stefania; Van Duijvenboden, Stefan; Klena, Nikolai T; Gabriel, George C; Liu, Xiaoqin; Gulec, Cagri; Grarup, Niels; Haessler, Jeffrey; Hall, Leanne M; Iorio, Annamaria; Isaacs, Aaron; Li-Gao, Ruifang; Lin, Honghuang; Liu, Ching-Ti; Lyytikäinen, Leo-Pekka; Marten, Jonathan; Mei, Hao; Müller-Nurasyid, Martina; Orini, Michele; Padmanabhan, Sandosh; Radmanesh, Farid; Ramirez, Julia; Robino, Antonietta; Schwartz, Molly; van Setten, Jessica; Smith, Albert V; Verweij, Niek; Warren, Helen R; Weiss, Stefan; Alonso, Alvaro; Arnar, David O; Bots, Michiel L; de Boer, Rudolf A; Dominiczak, Anna F; Eijgelsheim, Mark; Ellinor, Patrick T; Guo, Xiuqing; Felix, Stephan B; Linneberg, Allan; Pedersen, Oluf; Hansen, Torben; Kanters, Jørgen K; et al.

    In: Genome Biology, Vol. 19, 87, 17.07.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum. / Crusell, Mie Korslund Wiinblad; Hansen, Tue Haldor; Nielsen, Trine; Allin, Kristine Højgaard; Rühlemann, Malte C.; Damm, Peter; Vestergaard, Henrik; Rørbye, Christina; Jørgensen, Niklas Rye; Christiansen, Ole Bjarne; Heinsen, Femke-anouska; Franke, Andre; Hansen, Torben; Lauenborg, Jeannet; Pedersen, Oluf.

    In: Microbiome, Vol. 6, 89, 15.05.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity. / Kloppenborg, Julie T; Fonvig, Cilius E; Nielsen, Tenna R H; Mollerup, Pernille M; Bøjsøe, Christine; Pedersen, Oluf; Johannesen, Jesper; Hansen, Torben; Holm, Jens-Christian.

    In: Pediatric Diabetes, Vol. 19, No. 3, 05.2018, p. 356-365.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Aberrant intestinal microbiota in individuals with prediabetes. / Allin, Kristine Højgaard; Tremaroli, Valentina; Caesar, Robert; Jensen, Benjamin Anderschou Holbech; Damgaard, Mads Thue Fejerskov ; Bahl, Martin I; Licht, Tine R; Hansen, Tue Haldor; Nielsen, Trine; Dantoft, Thomas M; Linneberg, Allan; Jørgensen, Torben; Vestergaard, Henrik; Kristiansen, Karsten; Franks, Paul W.; IMI-DIRECT consortium ; Hansen, Torben; Bäckhed, Gert Fredrik; Pedersen, Oluf Borbye.

    In: Diabetologia, Vol. 61, No. 4, 04.2018, p. 810-820.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. / Mahajan, Anubha; Wessel, Jennifer; Willems, Sara M; Zhao, Wei; Robertson, Neil R; Chu, Audrey Y; Gan, Wei; Kitajima, Hidetoshi; Taliun, Daniel; Rayner, N William; Guo, Xiuqing; Lu, Yingchang; Li, Man; Jensen, Richard A; Hu, Yao; Huo, Shaofeng; Lohman, Kurt K; Zhang, Weihua; Cook, James P; Prins, Bram Peter; Flannick, Jason; Grarup, Niels; Trubetskoy, Vassily Vladimirovich; Kravic, Jasmina; Kim, Young Jin; Rybin, Denis V; Yaghootkar, Hanieh; Müller-Nurasyid, Martina; Meidtner, Karina; Li-Gao, Ruifang; Varga, Tibor V; Marten, Jonathan; Li, Jin; Afzal, Shoaib; Bork-Jensen, Jette; Tybjærg-Hansen, Anne; Jørgensen, Marit E; Jørgensen, Torben; Kovacs, Peter; Linneberg, Allan; Liu, Jun; Nielsen, Sune F; Rode, Line; Witte, Daniel R; Hansen, Torben; Karpe, Fredrik; Lind, Lars; Loos, Ruth J F; Nordestgaard, Børge G; Pedersen, Oluf; ExomeBP Consortium.

    In: Nature Genetics, Vol. 50, No. 4, 04.2018, p. 559-571.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The association of IgA deficiency on infection rate, self-perceived health, and levels of C-reactive protein in healthy blood donors. / Hauge, Sabina Chaudhary; Jensen, Charlotte Kæstel; Nielsen, Leif Kofoed; Pedersen, Ole B.; Sørensen, Erik; Thørner, Lise Wegner; Hjalgrim, Henrik; Erikstrup, Christian; Nielsen, Kaspar René; Kaspersen, Kathrine Agergård; Didriksen, Maria; Dziegiel, Morten; Ullum, Henrik.

    In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica, Vol. 126, No. 3, 01.03.2018, p. 248-256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans. / Hansen, Tue Haldor; Madsen, Marie Terese Barlebo; Jørgensen, Niklas Rye; Cohen, Arieh S; Hansen, Torben; Vestergaard, Henrik; Pedersen, Oluf Borbye; Allin, Kristine Højgaard.

    In: European Journal of Clinical Nutrition, Vol. 72, No. 7, 23.01.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. / Bonàs-Guarch, Sílvia; Guindo-Martínez, Marta; Miguel-Escalada, Irene; Grarup, Niels; Sebastian, David; Rodriguez-Fos, Elias; Sánchez, Friman; Planas-Fèlix, Mercè; Cortes-Sánchez, Paula; González, Santi; Timshel, Pascal; Pers, Tune H; Morgan, Claire C; Moran, Ignasi; Atla, Goutham; González, Juan R; Puiggros, Montserrat; Martí, Jonathan; Andersson, Ehm A; Díaz, Carlos; Badia, Rosa M; Udler, Miriam; Leong, Aaron; Kaur, Varindepal; Flannick, Jason; Jørgensen, Torben; Linneberg, Allan; Jørgensen, Marit E; Witte, Daniel R; Christensen, Cramer; Brandslund, Ivan; Appel, Emil V; Scott, Robert A; Luan, Jian'an; Langenberg, Claudia; Wareham, Nicholas J; Pedersen, Oluf; Zorzano, Antonio; Florez, Jose C; Hansen, Torben; Ferrer, Jorge; Mercader, Josep Maria; Torrents, David.

    In: Nature Communications, Vol. 9, 321, 22.01.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    In vivo and ex vivo inflammatory markers of common metabolic phenotypes in humans. / Mærkedahl, Rasmus Baadsgaard; Frøkiær, Hanne; Stenbæk, Marie Grøntved; Nielsen, Camilla Betak; Lind, Mads Vendelbo; Lundtoft, Christian; Bohr, Marietta Boje; Ibrügger, Sabine; Metzdorff, Stine Broeng; Vestergaard, Henrik; Pedersen, Oluf Borbye; Lauritzen, Lotte.

    In: Metabolic Syndrome and Related Disorders, Vol. 16, No. 1, 2018, p. 29-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links. / Pedersen, Helle Krogh; Forslund, Sofia K; Gudmundsdottir, Valborg; Petersen, Anders Østergaard; Hildebrand, Falk; Hyötyläinen, Tuulia; Nielsen, Trine; Hansen, Torben; Bork, Peer; Ehrlich, S. Dusko; Brunak, Søren; Oresic, Matej; Pedersen, Oluf; Nielsen, Henrik Bjørn.

    In: Nature Protocols, Vol. 13, No. 12, 2018, p. 2781-2800.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes. / Van Zuydam, Natalie R.; Ahlqvist, Emma; Sandholm, Niina; Deshmukh, Harshal; William Rayner, N.; Abdalla, Moustafa; Ladenvall, Claes; Ziemek, Daniel; Fauman, Eric; Robertson, Neil R.; McKeigue, Paul M.; Valo, Erkka; Forsblom, Carol; Harjutsalo, Valma; Perna, Annalisa; Rurali, Erica; Loredana Marcovecchio, M.; Igo, Robert P.; Lajer, Maria; Ahluwalia, Tarunveer S.; Linneberg, Allan; Witte, Daniel R.; Grarup, Niels; Pedersen, Oluf; Hansen, Torben; Rossing, Peter; SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium.

    In: Diabetes, Vol. 67, No. 7, 2018, p. 1414-1427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults. / Hansen, Lea Benedicte Skov; Roager, Henrik Munch; Søndertoft, Nadja Buus; Gøbel, Rikke Juul; Kristensen, Mette Bredal; Vallès-Colomer, Mireia; Vieira-Silva, Sara; Ibrügger, Sabine; Lind, Mads Vendelbo; Mærkedahl, Rasmus Baadsgaard; Bahl, Martin Iain; Madsen, Mia Linda; Havelund, Jesper; Falony, Gwen; Tetens, Inge ; Nielsen, Trine; Allin, Kristine Højgaard; Frandsen, Henrik Lund; Hartmann, Bolette; Holst, Jens Juul; Sparholt, Morten H; Holck, Jesper; Blennow, Andreas; Moll, Janne Marie; Meyer, Anne S; Hoppe, Camilla; Poulsen, Jørgen H; Carvalho, Vera; Sagnelli, Domenico; Dalgaard, Marlene Danner; Christensen, Anders Fogh; Lydolph, Magnus; Ross, Alistair B; Villas-Bôas, Silas G; Brix, Susanne; Sicheritz-Pontén, Thomas; Buschard, Karsten; Linneberg, Allan René; Rumessen, Jüri Johannes; Ekstrøm, Claus Thorn; Ritz, Christian; Kristiansen, Karsten; Nielsen, H Bjørn; Vestergaard, Henrik; Færgeman, Nils J; Raes, Jeroen; Frøkiær, Hanne; Hansen, Torben; Lauritzen, Lotte; Gupta, Ramneek; Licht, Tine Rask; Pedersen, Oluf Borbye.

    In: Nature Communications, Vol. 9, 4630, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Application of urinary proteomics as possible risk predictor of renal and cardiovascular complications in patients with type 2-diabetes and microalbuminuria. / Oellgaard, Jens; Gæde, Peter; Persson, Frederik; Rossing, Peter; Parving, Hans-Henrik; Pedersen, Oluf.

    In: Journal of Diabetes and its Complications, Vol. 32, No. 12, 2018, p. 1133-1140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma : a Mendelian randomization meta-analysis. / Skaaby, Tea; Taylor, Amy E.; Jacobsen, Rikke K.; Møllehave, Line T.; Friedrich, Nele; Thuesen, Betina H.; Shabanzadeh, Daniel Mønsted; Paternoster, Lavinia; Völker, Uwe; Nauck, Matthias; Völzke, Henry; Munafò, Marcus; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben; Grarup, Niels; Linneberg, Allan.

    In: European Journal of Clinical Nutrition, Vol. 72, No. 2, 2018, p. 264–271.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios. / Matey-Hernandez, Maria Luisa; Danish Pan Genome Consortium ; Brunak, Søren; Izarzugaza, Jose M.G.; Sørensen, Lasse Maretty; Sibbesen, Jonas Andreas; Liu, Siyang; Belling, Kirstine G; Have, Christian Theil; Bork-Jensen, Jette; Sun, Jihua; Hansen, Torben; Krogh, Anders; Sørensen, Thorkild I.A.; Pedersen, Oluf Borbye; Wang, Jun; Eiberg, Hans Rudolf Lytchoff; Kristiansen, Karsten.

    In: BMC Bioinformatics, Vol. 19, 239, 2018, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans. / Hansen, Tue H.; Madsen, Marie T.B.; Jørgensen, Niklas R.; Cohen, Arieh S.; Hansen, Torben; Vestergaard, Henrik; Pedersen, Oluf; Allin, Kristine H.

    In: European Journal of Clinical Nutrition, Vol. 72, 2018, p. 1046-1054.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest. / Andreasen, Laura; Ghouse, Jonas; Skov, Morten W.; Have, Christian T.; Ahlberg, Gustav; Rasmussen, Peter V.; Linneberg, Allan; Pedersen, Oluf; Platonov, Pyotr G.; Haunsø, Stig; Svendsen, Jesper H.; Hansen, Torben; Kanters, Jørgen K.; Olesen, Morten S.

    In: Frontiers in Physiology, Vol. 9, 894, 2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis. / Sustarsic, Elahu G; Ma, Tao; Lynes, Matthew D; Larsen, Michael; Karavaeva, Iuliia; Havelund, Jesper F; Nielsen, Carsten H; Jedrychowski, Mark P; Moreno-Torres, Marta; Lundh, Morten; Plucinska, Kaja; Jespersen, Naja Z; Grevengoed, Trisha J; Kramar, Barbara; Peics, Julia; Hansen, Jakob B; Shamsi, Farnaz; Forss, Isabel; Neess, Ditte; Keipert, Susanne; Wang, Jianing; Stohlmann, Katharina; Brandslund, Ivan; Christensen, Cramer; Jørgensen, Marit E; Linneberg, Allan; Pedersen, Oluf; Kiebish, Michael A; Qvortrup, Klaus; Han, Xianlin; Pedersen, Bente Klarlund; Jastroch, Martin; Mandrup, Susanne; Kjær, Andreas; Gygi, Steven P; Hansen, Torben; Gillum, Matthew P; Grarup, Niels; Emanuelli, Brice; Nielsen, Søren; Scheele, Camilla; Tseng, Yu-Hua; Færgeman, Nils J; Gerhart-Hines, Zachary.

    In: Cell Metabolism, Vol. 28, No. 1, 2018, p. 159-174.e11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations. / Nielsen, Tenna Ruest Haarmark; Fonvig, Cilius Esmann; Dahl, Maria; Mollerup, Pernille Maria; Lausten-Thomsen, Ulrik; Pedersen, Oluf; Hansen, Torben; Holm, Jens-Christian.

    In: P L o S One, Vol. 13, No. 2, e0190576, 2018, p. 1-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. / Lin, Honghuang; van Setten, Jessica; Smith, Albert V; Bihlmeyer, Nathan A; Warren, Helen R; Brody, Jennifer A; Radmanesh, Farid; Hall, Leanne; Grarup, Niels; Müller-Nurasyid, Martina; Boutin, Thibaud; Verweij, Niek; Lin, Henry J; Li-Gao, Ruifang; van den Berg, Marten E; Marten, Jonathan; Weiss, Stefan; Prins, Bram P; Haessler, Jeffrey; Lyytikäinen, Leo-Pekka; Mei, Hao; Harris, Tamara B; Launer, Lenore J; Li, Man; Alonso, Alvaro; Soliman, Elsayed Z; Connell, John M; Huang, Paul L; Weng, Lu-Chen; Jameson, Heather S; Hucker, William; Hanley, Alan; Tucker, Nathan R; Chen, Yii-Der Ida; Bis, Joshua C; Rice, Kenneth M; Sitlani, Colleen M; Kors, Jan A; Xie, Zhijun; Wen, Chengping; Magnani, Jared W; Nelson, Christopher P; Kanters, Jørgen K.; Sinner, Moritz F; Strauch, Konstantin; Peters, Annette; Waldenberger, Melanie; Meitinger, Thomas; Bork-Jensen, Jette; Pedersen, Oluf; Linneberg, Allan; Rudan, Igor; de Boer, Rudolf A; van der Meer, Peter; Yao, Jie; Guo, Xiuqing; Taylor, Kent D; Sotoodehnia, Nona; Rotter, Jerome I; Mook-Kanamori, Dennis O; Trompet, Stella; Rivadeneira, Fernando; Uitterlinden, André; Eijgelsheim, Mark; Padmanabhan, Sandosh; Smith, Blair H; Völzke, Henry; Felix, Stephan B; Homuth, Georg; Völker, Uwe; Mangino, Massimo; Spector, Timothy D; Bots, Michiel L; Perez, Marco; Kähönen, Mika; Raitakari, Olli T; Gudnason, Vilmundur; Arking, Dan E; Munroe, Patricia B; Psaty, Bruce M; van Duijn, Cornelia M; Benjamin, Emelia J; Rosand, Jonathan; Samani, Nilesh J; Hansen, Torben; Kääb, Stefan; Polasek, Ozren; van der Harst, Pim; Heckbert, Susan R; Jukema, J Wouter; Stricker, Bruno H; Hayward, Caroline; Dörr, Marcus; Jamshidi, Yalda; Asselbergs, Folkert W; Kooperberg, Charles; Lehtimäki, Terho; Wilson, James G; Ellinor, Patrick T; Lubitz, Steven A; Isaacs, Aaron.

    In: Circulation. Genomic and precision medicine, Vol. 11, No. 5, e002037, 2018, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses. / Engelbrechtsen, Line; Mahendran, Yuvaraj; Jonsson, Anna; Gjesing, Anette Prior; Weeke, Peter E; Jørgensen, Marit E.; Færch, Kristine; Witte, Daniel R.; Holst, Jens J.; Jørgensen, Torben; Grarup, Niels; Pedersen, Oluf; Vestergaard, Henrik; Torekov, Signe; Kanters, Jørgen K; Hansen, Torben.

    In: B M C Genetics, Vol. 19, No. 1, 15, 2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

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