Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2018
  2. Published

    Aberrant intestinal microbiota in individuals with prediabetes. / Allin, Kristine Højgaard; Tremaroli, Valentina; Caesar, Robert; Jensen, Benjamin Anderschou Holbech; Damgaard, Mads Thue Fejerskov ; Bahl, Martin I; Licht, Tine R; Hansen, Tue Haldor; Nielsen, Trine; Dantoft, Thomas M; Linneberg, Allan; Jørgensen, Torben; Vestergaard, Henrik; Kristiansen, Karsten; Franks, Paul W.; IMI-DIRECT consortium ; Hansen, Torben; Bäckhed, Gert Fredrik; Pedersen, Oluf Borbye.

    In: Diabetologia, Vol. 61, No. 4, 04.2018, p. 810-820.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest. / Andreasen, Laura; Ghouse, Jonas; Skov, Morten W.; Have, Christian T.; Ahlberg, Gustav; Rasmussen, Peter V.; Linneberg, Allan; Pedersen, Oluf; Platonov, Pyotr G.; Haunsø, Stig; Svendsen, Jesper H.; Hansen, Torben; Kanters, Jørgen K.; Olesen, Morten S.

    In: Frontiers in Physiology, Vol. 9, 894, 2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population. / Appel, Vincent Rosenbaum; Moltke, Ida; Jørgensen, Marit E.; Bjerregaard, Peter; Linneberg, Allan; Pedersen, Oluf Borbye; Albrechtsen, Anders; Hansen, Torben; Grarup, Niels.

    In: European Journal of Human Genetics, Vol. 26, No. 6, 2018, p. 868-875.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. / Bihlmeyer, Nathan A.; Brody, Jennifer A.; Smith, Albert Vernon; Warren, Helen R.; Lin, Honghuang; Isaacs, Aaron; Liu, Ching-Ti; Marten, Jonathan; Radmanesh, Farid; Hall, Leanne M.; Grarup, Niels; Mei, Hao; Muller-Nurasyid, Martina; Huffman, Jennifer E.; Verweij, Niek; Guo, Xiuqing; Yao, Jie; Li-Gao, Ruifang; van den Berg, Marten; Weiss, Stefan; Prins, Bram P.; van Setten, Jessica; Haessler, Jeffrey; Lyytikainen, Leo-Pekka; Li, Man; Alonso, Alvaro; Soliman, Elsayed Z.; Bis, Joshua C.; Austin, Tom; Chen, Yii-Der Ida; Psaty, Bruce M.; Harrris, Tamara B.; Launer, Lenore J.; Padmanabhan, Sandosh; Dominiczak, Anna; Huang, Paul L.; Xie, Zhijun; Ellinor, Patrick T.; Kors, Jan A.; Campbell, Archie; Murray, Alison D.; Nelson, Christopher P.; Tobin, Martin D.; Bork-Jensen, Jette; Hansen, Torben; Pedersen, Oluf; Linneberg, Allan; Sinner, Moritz F.; Peters, Annette; Kanters, Jørgen K.

    In: Circulation. Genomic and precision medicine, Vol. 11, No. 1, e001758, 2018, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. / Bonàs-Guarch, Sílvia; Guindo-Martínez, Marta; Miguel-Escalada, Irene; Grarup, Niels; Sebastian, David; Rodriguez-Fos, Elias; Sánchez, Friman; Planas-Fèlix, Mercè; Cortes-Sánchez, Paula; González, Santi; Timshel, Pascal; Pers, Tune H; Morgan, Claire C; Moran, Ignasi; Atla, Goutham; González, Juan R; Puiggros, Montserrat; Martí, Jonathan; Andersson, Ehm A; Díaz, Carlos; Badia, Rosa M; Udler, Miriam; Leong, Aaron; Kaur, Varindepal; Flannick, Jason; Jørgensen, Torben; Linneberg, Allan; Jørgensen, Marit E; Witte, Daniel R; Christensen, Cramer; Brandslund, Ivan; Appel, Emil V; Scott, Robert A; Luan, Jian'an; Langenberg, Claudia; Wareham, Nicholas J; Pedersen, Oluf; Zorzano, Antonio; Florez, Jose C; Hansen, Torben; Ferrer, Jorge; Mercader, Josep Maria; Torrents, David.

    In: Nature Communications, Vol. 9, 321, 22.01.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes. / Cousminer, Diana L.; Ahlqvist, Emma; Mishra, Rajashree; Andersen, Mette K.; Chesi, Alessandra; Hawa, Mohammad I.; Davis, Asa; Hodge, Kenyaita M.; Bradfield, Jonathan P.; Zhou, Kaixin; Guy, Vanessa C.; Akerlund, Mikael; Wod, Mette; Fritsche, Lars G.; Vestergaard, Henrik; Snyder, James; Højlund, Kurt; Linneberg, Allan; Karajamaki, Annemari; Brandslund, Ivan; Kim, Cecilia E.; Witte, Daniel; Sorgjerd, Elin Pettersen; Brillon, David J.; Pedersen, Oluf; Beck-Nielsen, Henning; Grarup, Niels; Pratley, Richard E.; Rickels, Michael R.; Vella, Adrian; Ovalle, Fernando; Melander, Olle; Harris, Ronald I.; Varvel, Stephen; Grill, Valdemar E. R.; Hakonarson, Hakon; Froguel, Philippe; Lonsdale, John T.; Mauricio, Didac; Schloot, Nanette C.; Khunti, Kamlesh; Greenbaum, Carla J.; Asvold, Bjorn Olav; Yderstraede, Knud B.; Pearson, Ewan R.; Schwartz, Stanley; Voight, Benjamin F.; Hansen, Torben; Tuomi, Tiinamaija; Boehm, Bernhard O.; Groop, Leif; Leslie, R. David; Grant, Struan F. A.

    In: Diabetes Care, Vol. 41, No. 11, 2018, p. 2396-2403.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum. / Crusell, Mie Korslund Wiinblad; Hansen, Tue Haldor; Nielsen, Trine; Allin, Kristine Højgaard; Rühlemann, Malte C.; Damm, Peter; Vestergaard, Henrik; Rørbye, Christina; Jørgensen, Niklas Rye; Christiansen, Ole Bjarne; Heinsen, Femke-anouska; Franke, Andre; Hansen, Torben; Lauenborg, Jeannet; Pedersen, Oluf.

    In: Microbiome, Vol. 6, 89, 15.05.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses. / Engelbrechtsen, Line; Mahendran, Yuvaraj; Jonsson, Anna; Gjesing, Anette Prior; Weeke, Peter E; Jørgensen, Marit E.; Færch, Kristine; Witte, Daniel R.; Holst, Jens J.; Jørgensen, Torben; Grarup, Niels; Pedersen, Oluf; Vestergaard, Henrik; Torekov, Signe; Kanters, Jørgen K; Hansen, Torben.

    In: B M C Genetics, Vol. 19, No. 1, 15, 2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese. / Graae, Anne Sofie; Hollensted, Mette; Kloppenborg, Julie T.; Mahendran, Yuvaraj; Schnurr, Theresia M.; Appel, Emil Vincent R.; Rask, Johanne; Nielsen, Tenna R.H.; Johansen, Mia; Linneberg, Allan; Jørgensen, Marit E.; Grarup, Niels; Kadarmideen, Haja N.; Holst, Birgitte; Pedersen, Oluf; Holm, Jens-Christian; Hansen, Torben.

    In: Diabetologia, Vol. 61, No. 8, 08.2018, p. 1769-1779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population. / Grarup, Niels; Moltke, Ida; Andersen, Mette K.; Bjerregaard, Peter; Larsen, Christina V.L.; Dahl-Petersen, Inger K.; Jørsboe, Emil; Tiwari, Hemant K.; Hopkins, Scarlett E.; Wiener, Howard W.; Boyer, Bert B.; Linneberg, Allan; Pedersen, Oluf; Jørgensen, Marit E.; Albrechtsen, Anders; Hansen, Torben.

    In: Diabetologia, Vol. 61, No. 9, 09.2018, p. 2005–2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes. / Grarup, Niels; Moltke, Ida; Andersen, Mette Korre; Dalby, Maria; Vitting-Seerup, Kristoffer; Kern, Timo Sebastian; Mahendran, Yuvaraj; Jørsboe, Emil; Larsen, Christina Viskum Lytken; Dahl-Petersen, Inger Katrine; Gilly, Arthur; Suveges, Daniel; Dedoussis, George; Zeggini, Eleftheria; Pedersen, Oluf Borbye; Andersson, Robin; Bjerregaard, Peter; Jørgensen, Marit Eika; Albrechtsen, Anders; Hansen, Torben.

    In: Nature Genetics, Vol. 50, No. 2, 2018, p. 172-174.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences. / Gæde, Joachim; Nielsen, Trine; Madsen, Mia L; Toft, Ulla; Jørgensen, Torben; Overvad, Kim; Tjønneland, Anne; Hansen, Torben; Allin, Kristine H; Pedersen, Oluf.

    In: Nutrition Journal, Vol. 17, No. 1, 91, 06.10.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults. / Hansen, Lea Benedicte Skov; Roager, Henrik Munch; Søndertoft, Nadja Buus; Gøbel, Rikke Juul; Kristensen, Mette Bredal; Vallès-Colomer, Mireia; Vieira-Silva, Sara; Ibrügger, Sabine; Lind, Mads Vendelbo; Mærkedahl, Rasmus Baadsgaard; Bahl, Martin Iain; Madsen, Mia Linda; Havelund, Jesper; Falony, Gwen; Tetens, Inge ; Nielsen, Trine; Allin, Kristine Højgaard; Frandsen, Henrik Lund; Hartmann, Bolette; Holst, Jens Juul; Sparholt, Morten H; Holck, Jesper; Blennow, Andreas; Moll, Janne Marie; Meyer, Anne S; Hoppe, Camilla; Poulsen, Jørgen H; Carvalho, Vera; Sagnelli, Domenico; Dalgaard, Marlene Danner; Christensen, Anders Fogh; Lydolph, Magnus; Ross, Alistair B; Villas-Bôas, Silas G; Brix, Susanne; Sicheritz-Pontén, Thomas; Buschard, Karsten; Linneberg, Allan René; Rumessen, Jüri Johannes; Ekstrøm, Claus Thorn; Ritz, Christian; Kristiansen, Karsten; Nielsen, H Bjørn; Vestergaard, Henrik; Færgeman, Nils J; Raes, Jeroen; Frøkiær, Hanne; Hansen, Torben; Lauritzen, Lotte; Gupta, Ramneek; Licht, Tine Rask; Pedersen, Oluf Borbye.

    In: Nature Communications, Vol. 9, 4630, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans. / Hansen, Tue H.; Madsen, Marie T.B.; Jørgensen, Niklas R.; Cohen, Arieh S.; Hansen, Torben; Vestergaard, Henrik; Pedersen, Oluf; Allin, Kristine H.

    In: European Journal of Clinical Nutrition, Vol. 72, 2018, p. 1046-1054.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Impact of a vegan diet on the human salivary microbiota. / Hansen, Tue H.; Kern, Timo; Bak, Emilie G.; Kashani, Alireza; Allin, Kristine H.; Nielsen, Trine; Hansen, Torben; Pedersen, Oluf.

    In: Scientific Reports, Vol. 8, 5847, 2018, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The effect of drinking water pH on the human gut microbiota and glucose regulation : results of a randomized controlled cross-over intervention. / Hansen, Tue H.; Thomassen, Mette T.; Madsen, Mia L.; Kern, Timo; Bak, Emilie G.; Kashani, Alireza; Allin, Kristine H; Hansen, Torben; Pedersen, Oluf.

    In: Scientific Reports, Vol. 8, 16626, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans. / Hansen, Tue Haldor; Madsen, Marie Terese Barlebo; Jørgensen, Niklas Rye; Cohen, Arieh S; Hansen, Torben; Vestergaard, Henrik; Pedersen, Oluf Borbye; Allin, Kristine Højgaard.

    In: European Journal of Clinical Nutrition, Vol. 72, No. 7, 23.01.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The association of IgA deficiency on infection rate, self-perceived health, and levels of C-reactive protein in healthy blood donors. / Hauge, Sabina Chaudhary; Jensen, Charlotte Kæstel; Nielsen, Leif Kofoed; Pedersen, Ole B.; Sørensen, Erik; Thørner, Lise Wegner; Hjalgrim, Henrik; Erikstrup, Christian; Nielsen, Kaspar René; Kaspersen, Kathrine Agergård; Didriksen, Maria; Dziegiel, Morten; Ullum, Henrik.

    In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica, Vol. 126, No. 3, 01.03.2018, p. 248-256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children. / Hollensted, Mette; Fogh, Mette; Schnurr, Theresia M; Kloppenborg, Julie T; Have, Christian T; Nielsen, Tenna Ruest Haarmark; Rask, Johanne; Asp Vonsild Lund, Morten; Frithioff-Bøjsøe, Christine; Østergaard Johansen, Mia; Vincent Rosenbaum Appel, Emil; Mahendran, Yuvaraj; Grarup, Niels; Kadarmideen, Haja N; Pedersen, Oluf; Holm, Jens-Christian; Hansen, Torben.

    In: Obesity, Vol. 26, No. 12, 2018, p. 1915-1922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood : a family-based study. / Hollensted, Mette; Ekstrøm, Claus T.; Pedersen, Oluf; Eiberg, Hans; Hansen, Torben; Gjesing, Anette Prior.

    In: BMC Medical Genetics, Vol. 19, 207, 2018, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Increase in clinically recorded type 2 diabetes after colectomy. / Jensen, Anders B; Sørensen, Thorkild Ia; Pedersen, Oluf; Jess, Tine; Brunak, Søren; Allin, Kristine H.

    In: eLife, Vol. 7, e37420, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Indicator of RNA oxidation in urine for the prediction of mortality in patients with type 2 diabetes and microalbuminuria : a post-hoc analysis of the Steno-2 trial. / Kjær, Laura Kofoed; Oellgaard, Jens; Henriksen, Trine; Gaede, Peter; Pedersen, Oluf; Poulsen, Henrik Enghusen.

    In: Free Radical Biology and Medicine, Vol. 129, 2018, p. 247-255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity. / Kloppenborg, Julie T; Fonvig, Cilius E; Nielsen, Tenna R H; Mollerup, Pernille M; Bøjsøe, Christine; Pedersen, Oluf; Johannesen, Jesper; Hansen, Torben; Holm, Jens-Christian.

    In: Pediatric Diabetes, Vol. 19, No. 3, 05.2018, p. 356-365.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The effect of impaired glucose metabolism on weight loss in multidisciplinary childhood obesity treatment. / Kloppenborg, Julie T.; Gamborg, Michael; Fonvig, Cilius E.; Nielsen, Tenna R.H.; Pedersen, Oluf; Johannesen, Jesper; Hansen, Torben; Holm, Jens-Christian.

    In: Pediatric Diabetes, Vol. 19, No. 3, 2018, p. 366-374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography. / Krogager, Maria Lukacs; Skals, Regitze Kuhr; Appel, Emil Vincent R.; Schnurr, Theresia Maria; Engelbrechtsen, Line; Have, Christian Theil; Pedersen, Oluf Borbye; Engstrøm, Thomas; Roden, Dan M.; Gislason, Gunnar; Poulsen, Henrik Enghusen; Køber, Lars; Stender, Steen; Hansen, Torben; Grarup, Niels; Andersson, Charlotte; Torp-Pedersen, Christian; Weeke, Peter E.

    In: P L o S One, Vol. 13, No. 12, e0208645, 2018, p. 1-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

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