Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents. / Fonvig, Cilius Esmann; Chabanova, Elizaveta; Andersson, Ehm Astrid; Ohrt, Johanne Dam; Pedersen, Oluf; Hansen, Torben; Thomsen, Henrik S; Holm, Jens-Christian.

    In: PLOS ONE, Vol. 10, No. 8, e0135018, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease. / Gretarsdottir, Solveig; Helgason, Hannes; Helgadottir, Anna; Sigurdsson, Asgeir; Thorleifsson, Gudmar; Magnusdottir, Audur; Oddsson, Asmundur; Steinthorsdottir, Valgerdur; Rafnar, Thorunn; de Graaf, Jacqueline; Daneshpour, Maryam S; Hedayati, Mehdi; Azizi, Fereidoun; Grarup, Niels; Jørgensen, Torben; Vestergaard, Henrik; Hansen, Torben; Eyjolfsson, Gudmundur; Sigurdardottir, Olof; Olafsson, Isleifur; Kiemeney, Lambertus A; Pedersen, Oluf; Sulem, Patrick; Thorgeirsson, Gudmundur; Gudbjartsson, Daniel F; Holm, Hilma; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: P L o S Genetics, Vol. 11, No. 9, e1005379, 09.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A glycogene mutation map for discovery of diseases of glycosylation. / Hansen, Lars; Lind-Thomsen, Allan; Joshi, Hiren J; Pedersen, Nis Borbye; Have, Christian Theil; Kong, Yun; Wang, Shengjun; Sparso, Thomas; Grarup, Niels; Vester-Christensen, Malene Bech; Schjoldager, Katrine; Freeze, Hudson H; Hansen, Torben; Pedersen, Oluf; Henrissat, Bernard; Mandel, Ulla; Clausen, Henrik; Wandall, Hans H; Bennett, Eric P.

    In: Glycobiology, Vol. 25, No. 2, 2015, p. 211-224.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion. / Yaghootkar, Hanieh; Stancáková, Alena; Freathy, Rachel M; Vangipurapu, Jagadish; Weedon, Michael N; Xie, Weijia; Wood, Andrew R; Ferrannini, Ele; Mari, Andrea; Ring, Susan M; Lawlor, Debbie A; Davey Smith, George; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Steinthorsdottir, Valgerdur; Guðbjartsson, Daniel F; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Stefansson, Kari; Hattersley, Andrew T; Walker, Mark; Morris, Andrew D; McCarthy, Mark I; Palmer, Colin N A; Laakso, Markku; Frayling, Timothy M.

    In: Diabetes, Vol. 64, No. 6, 06.2015, p. 2279-85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes. / Thomsen, Stine B; Gjesing, Anette Marianne Prior; Rathcke, Camilla N; Ekstrøm, Claus T; Eiberg, Hans; Hansen, Torben; Pedersen, Oluf; Vestergaard, Henrik.

    In: PLOS ONE, Vol. 10, No. 7, e0133672, 21.07.2015, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Asthma in patients with psoriasis. / Lønnberg, A S; Skov, Lone; Skytthe, A; Kyvik, K O; Pedersen, O B; Meteran, Howraman; Backer, V; Thomsen, S F.

    In: British Journal of Dermatology, 2015, p. 1660-1661.

    Research output: Contribution to journalLetterResearchpeer-review

  7. Published

    Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes : a case-control study. / Hollensted, Mette; Ahluwalia, Tarun Veer Singh; Have, Christian Theil; Grarup, Niels; Fonvig, Cilius Esmann; Nielsen, Tenna Ruest Haarmark; Trier, Cæcilie; Paternoster, Lavinia; Pedersen, Oluf; Holm, Jens-Christian; Sørensen, Thorkild I A; Hansen, Torben.

    In: BMC Medical Genetics, Vol. 16, 105, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans. / Pant, Sameer Dinkar; Karlskov-Mortensen, Peter; Jacobsen, Mette Juul; Cirera Salicio, Susanna; Kogelman, Lisette; Bruun, Camilla Vibeke Sichlau; Mark, Thomas; Jørgensen, Claus Bøttcher; Grarup, Niels; Appel, Emil Vincent Rosenbaum; Galjatovic, Ehm A. A.; Hansen, Torben; Pedersen, Oluf Borbye; Guerin, Maryse; Huby, Thierry; Lesnik, Philipppe; Meuwissen, Theo H. E.; Kadarmideen, Haja; Fredholm, Merete.

    In: PLOS ONE, Vol. 10, No. 9, e0137356, 08.09.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Dietary modulation of the gut microbiota - a randomised controlled trial in obese postmenopausal women. / Brahe, Lena Kirchner; Le Chatelier, Emmanuelle; Prifti, Edi; Pons, Nicolas; Kennedy, Sean; Blædel, Trine; Håkansson, Janet; Dalsgaard, Trine Kastrup; Hansen, Torben; Pedersen, Oluf Borbye; Astrup, Arne; Ehrlich, S Dusko; Larsen, Lesli Hingstrup.

    In: British Journal of Nutrition, Vol. 114, No. 3, 2015, p. 406-417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes. / Ahluwalia, Tarun Veer Singh; Allin, Kristine Højgaard; Sandholt, Camilla Helene; Sparsø, Thomas Hempel; Jørgensen, Marit Eika; Rowe, Michael; Christensen, Cramer; Brandslund, Ivan; Lauritzen, Torsten; Linneberg, Allan; Husemoen, Lise-Lotte; Jørgensen, Torben; Hansen, Torben; Grarup, Niels; Pedersen, Oluf.

    In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 4, 04.2015, p. E664-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. / Forslund, Kristoffer; Hildebrand, Falk; Nielsen, Trine; Falony, Gwen; Le Chatelier, Emmanuelle; Sunagawa, Shinichi; Prifti, Edi; Vieira-Silva, Sara; Gudmundsdottir, Valborg; Pedersen, Helle Krogh; Arumugam, Manimozhiyan; Kristiansen, Karsten; Yvonne Voigt, Anita; Vestergaard, Henrik; Hercog, Rajna; Igor Costea, Paul; Roat Kultima, Jens; Li, Junhua; Jørgensen, Torben; Levenez, Florence; Dore, Joël; Nielsen, Henrik Bjørn; Brunak, Søren; Raes, Jeroen; Hansen, Torben; Wang, Jun; Dusko Ehrlich, S.; Bork, Peer; Pedersen, Oluf Borbye.

    In: Nature, Vol. 528, No. 7581, 2015, p. 262-266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism. / Mikkelsen, Kristian H; Frost, Morten; Bahl, Martin I; Licht, Tine R; Jensen, Ulrich S; Rosenberg, Jacob; Pedersen, Oluf; Hansen, Torben; Rehfeld, Jens F; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K.

    In: PLOS ONE, Vol. 10, No. 11, e0142352, 12.11.2015, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity : a population-based study. / Bonfils, Linéa; Ellervik, Christina; Friedrich, Nele; Linneberg, Allan; Sandholt, Camilla H.; Jørgensen, Marit E; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Allin, Kristine H.

    In: Diabetologia, Vol. 58, No. 3, 2015, p. 523-533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women. / Iepsen, Eva Pers Winning; Lundgren, Julie Rehné; Hartmann, Bolette; Pedersen, Oluf; Hansen, Torben; Jørgensen, Niklas R; Jensen, Jens-Erik Beck; Holst, Jens J; Madsbad, Sten; Torekov, Signe Sørensen.

    In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 8, 2015, p. 2909 –2917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data. / Gjesing, Anette Marianne Prior; Ribel-Madsen, Rasmus; Harder, Marie Neergaard; Eiberg, Hans; Grarup, Niels; Jørgensen, Torben; Ekstrøm, Claus T; Pedersen, Oluf; Hansen, Torben.

    In: Diabetologia, Vol. 58, No. 5, 05.2015, p. 1006-1012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. / Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; Mahajan, Anubha; Locke, Adam; William Rayner, N; Robertson, Neil; Scott, Robert A; Prokopenko, Inga; Scott, Laura J; Green, Todd; Sparso, Thomas; Thuillier, Dorothee; Yengo, Loic; Grallert, Harald; Wahl, Simone; Frånberg, Mattias; Strawbridge, Rona J; Kestler, Hans; Chheda, Himanshu; Eisele, Lewin; Gustafsson, Stefan; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Karssen, Lennart C; van Leeuwen, Elisabeth M; Willems, Sara M; Li, Man; Chen, Han; Fuchsberger, Christian; Kwan, Phoenix; Ma, Clement; Linderman, Michael; Lu, Yingchang; Thomsen, Soren K; Rundle, Jana K; Grarup, Niels; Have, Christian T; Jonsson, Anna; Jørgensen, Marit Eika; Jørgensen, Torben; Linneberg, Allan; Storm, Petter; Njølstad, Inger; Hansen, Torben; Pedersen, Oluf; Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium.

    In: Nature Genetics, Vol. 47, No. 12, 12.2015, p. 1415-25, 3 unpag. pages.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Genome-wide association studies of human adiposity: Zooming in on synapses. / Sandholt, Camilla H.; Grarup, Niels; Pedersen, Oluf; Hansen, Torben.

    In: Molecular and Cellular Endocrinology, Vol. 418, No. Part 2, 2015, p. 90-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex : The ADDITION-PRO Study. / Færch, Kristine; Torekov, Signe S; Vistisen, Dorte; Johansen, Nanna B; Witte, Daniel R; Jonsson, Anna; Pedersen, Oluf; Hansen, Torben; Lauritzen, Torsten; Sandbæk, Annelli; Holst, Jens Juul; Jørgensen, Marit E.

    In: Diabetes, Vol. 64, 07.2015, p. 2513-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Greenlandic Inuit show genetic signatures of diet and climate adaptation. / Fumagalli, Matteo; Moltke, Ida; Grarup, Niels; Racimo, Fernando; Bjerregaard, Peter; Jørgensen, Marit E.; Korneliussen, Thorfinn Sand; Gerbault, Pascale; Skotte, Line; Linneberg, Allan René; Christensen, Cramer; Brandslund, Ivan; Jørgensen, Torben; Huerta-Sánchez, Emilia; Schmidt, Erik Berg; Pedersen, Oluf Borbye; Hansen, Torben; Albrechtsen, Anders; Nielsen, Rasmus.

    In: Science (New York, N.Y.), Vol. 349, No. 6254, 2015, p. 1343-1347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants. / Dashti, Hassan S; Follis, Jack L; Smith, Caren E; Tanaka, Toshiko; Cade, Brian E; Gottlieb, Daniel J; Hruby, Adela; Jacques, Paul F; Lamon-Fava, Stefania; Richardson, Kris; Saxena, Richa; Scheer, Frank A J L; Kovanen, Leena; Bartz, Traci M; Perälä, Mia-Maria; Jonsson, Anna Elisabet; Frazier-Wood, Alexis C; Kalafati, Ioanna-Panagiota; Mikkilä, Vera; Partonen, Timo; Lemaitre, Rozenn N; Lahti, Jari; Hernandez, Dena G; Toft, Ulla; Johnson, W Craig; Kanoni, Stavroula; Raitakari, Olli T; Perola, Markus; Psaty, Bruce M; Ferrucci, Luigi; Grarup, Niels; Highland, Heather M; Rallidis, Loukianos; Kähönen, Mika; Havulinna, Aki S; Siscovick, David S; Räikkönen, Katri; Jørgensen, Torben; Rotter, Jerome I; Deloukas, Panos; Viikari, Jorma S A; Mozaffarian, Dariush; Linneberg, Allan; Seppälä, Ilkka; Hansen, Torben; Salomaa, Veikko; Gharib, Sina A; Eriksson, Johan G; Bandinelli, Stefania; Pedersen, Oluf; Rich, Stephen S; Dedoussis, George; Lehtimäki, Terho; Ordovás, José M.

    In: The American Journal of Clinical Nutrition, Vol. 101, No. 1, 01.2015, p. 135-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. / Mahajan, Anubha; Sim, Xueling; Ng, Hui Jin; Manning, Alisa; Rivas, Manuel A; Highland, Heather M; Locke, Adam E; Grarup, Niels; Im, Hae Kyung; Cingolani, Pablo; Flannick, Jason; Fontanillas, Pierre; Fuchsberger, Christian; Gaulton, Kyle J; Teslovich, Tanya M; Rayner, N William; Robertson, Neil R; Beer, Nicola L; Rundle, Jana K; Bork-Jensen, Jette; Ladenvall, Claes; Blancher, Christine; Buck, David; Buck, Gemma; Burtt, Noël P; Gabriel, Stacey; Gjesing, Anette Marianne Prior; Groves, Christopher J; Hollensted, Mette; Huyghe, Jeroen R; Jackson, Anne U; Jun, Goo; Justesen, Johanne Marie; Mangino, Massimo; Murphy, Jacquelyn; Neville, Matt; Onofrio, Robert; Small, Kerrin S; Stringham, Heather M; Syvänen, Ann-Christine; Trakalo, Joseph; Abecasis, Goncalo; Bell, Graeme I; Blangero, John; Cox, Nancy J; Duggirala, Ravindranath; Linneberg, Allan; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; T2D-GENES consortium and GoT2D consortium.

    In: P L o S Genetics, Vol. 11, No. 1, e1004876, 01.2015, p. 1-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes. / Hansen, Tue Haldor; Vestergaard, Henrik; Jørgensen, Torben; Jørgensen, Marit Eika; Lauritzen, Torsten; Brandslund, Ivan; Christensen, Cramer; Pedersen, Oluf Borbye; Hansen, Torben; Gjesing, Anette Marianne Prior.

    In: BMC Medical Genetics, Vol. 16, 17, 20.03.2015, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood. / Rönn, Tina; Volkov, Petr; Gillberg, Linn; Kokosar, Milana; Perfilyev, Alexander; Jacobsen, Anna Louisa; Jørgensen, Sine W; Brøns, Charlotte; Jansson, Per-Anders; Eriksson, Karl-Fredrik; Pedersen, Oluf; Hansen, Torben; Groop, Leif; Stener-Victorin, Elisabet; Vaag, Allan; Nilsson, Emma; Ling, Charlotte.

    In: Human Molecular Genetics, Vol. 24, No. 13, 01.07.2015, p. 3792-813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Insulin resistance as a physiological defense against metabolic stress : implications for the management of subsets of type 2 diabetes. / Nolan, Christopher J; Ruderman, Neil B; Kahn, Steven E; Pedersen, Oluf; Prentki, Marc.

    In: Diabetes, Vol. 64, No. 3, 03.2015, p. 673-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Intake of macro- and micronutrients in Danish vegans. / Kristensen, Nadja B; Madsen, Mia L; Hansen, Tue H; Allin, Kristine H; Hoppe, Camilla; Fagt, Sisse; Lausten, Mia S; Gøbel, Rikke J; Vestergaard, Henrik; Hansen, Torben; Pedersen, Oluf.

    In: Nutrition Journal, Vol. 14, No. 1, 115, 30.10.2015, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

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