Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young. / Østoft, Signe Harring; Bagger, Jonatan Ising; Hansen, Torben; Hartmann, Bolette; Pedersen, Oluf; Holst, Jens Juul; Knop, Filip Krag; Vilsbøll, Tina.

    In: European Journal of Endocrinology, Vol. 173, No. 2, 01.08.2015, p. 205-215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion. / Yaghootkar, Hanieh; Stancáková, Alena; Freathy, Rachel M; Vangipurapu, Jagadish; Weedon, Michael N; Xie, Weijia; Wood, Andrew R; Ferrannini, Ele; Mari, Andrea; Ring, Susan M; Lawlor, Debbie A; Davey Smith, George; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Steinthorsdottir, Valgerdur; Guðbjartsson, Daniel F; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Stefansson, Kari; Hattersley, Andrew T; Walker, Mark; Morris, Andrew D; McCarthy, Mark I; Palmer, Colin N A; Laakso, Markku; Frayling, Timothy M.

    In: Diabetes, Vol. 64, No. 6, 06.2015, p. 2279-85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study. / Winkler, Thomas W; Justice, Anne E; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F; Chu, Su; Czajkowski, Jacek; Esko, Tõnu; Fall, Tove; Kilpeläinen, Tuomas O; Lu, Yingchang; Mägi, Reedik; Mihailov, Evelin; Pers, Tune H; Rüeger, Sina; Teumer, Alexander; Ehret, Georg B; Ferreira, Teresa; Heard-Costa, Nancy L; Karjalainen, Juha; Lagou, Vasiliki; Mahajan, Anubha; Neinast, Michael D; Prokopenko, Inga; Simino, Jeannette; Teslovich, Tanya M; Jansen, Rick; Westra, Harm-Jan; White, Charles C; Absher, Devin; Ahluwalia, Tarun Veer Singh; Ahmad, Shafqat; Albrecht, Eva; Alves, Alexessander Couto; Bragg-Gresham, Jennifer L; de Craen, Anton J M; Bis, Joshua C; Bonnefond, Amélie; Boucher, Gabrielle; Banasik, Karina; Grarup, Niels; Hansen, Torben; Jørgensen, Torben; Krarup, Nikolaj T; Linneberg, Allan; Ribel-Madsen, Rasmus; Sparsø, Thomas H; Melbye, Mads; Pedersen, Oluf; Sørensen, Thorkild I A; CHARGE Consortium.

    In: P L o S Genetics, Vol. 11, No. 10, e1005378, 01.10.2015, p. 1-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. / Wessel, Jennifer; Chu, Audrey Y; Willems, Sara M; Wang, Shuai; Yaghootkar, Hanieh; Brody, Jennifer A; Dauriz, Marco; Hivert, Marie-France; Raghavan, Sridharan; Lipovich, Leonard; Hidalgo, Bertha; Fox, Keolu; Huffman, Jennifer E; An, Ping; Lu, Yingchang; Rasmussen-Torvik, Laura J; Grarup, Niels; Ehm, Margaret G; Li, Li; Baldridge, Abigail S; Stančáková, Alena; Abrol, Ravinder; Besse, Céline; Boland, Anne; Bork-Jensen, Jette; Fornage, Myriam; Freitag, Daniel F; Garcia, Melissa E; Guo, Xiuqing; Hara, Kazuo; Isaacs, Aaron; Jakobsdottir, Johanna; Lange, Leslie A; Layton, Jill C; Li, Man; Hua Zhao, Jing; Meidtner, Karina; Morrison, Alanna C; Nalls, Mike A; Peters, Marjolein J; Sabater-Lleal, Maria; Schurmann, Claudia; Silveira, Angela; Smith, Albert V; Southam, Lorraine; Allin, Kristine H; Jørgensen, Torben; Linneberg, Allan; Hansen, Torben; Pedersen, Oluf; EPIC-InterAct Consortium.

    In: Nature Communications, Vol. 6, 29.01.2015, p. 5897.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes. / Thomsen, Stine B; Gjesing, Anette Marianne Prior; Rathcke, Camilla N; Ekstrøm, Claus T; Eiberg, Hans; Hansen, Torben; Pedersen, Oluf; Vestergaard, Henrik.

    In: PLOS ONE, Vol. 10, No. 7, e0133672, 21.07.2015, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG : a novel genometabolic cross-link between CD300LG and common metabolic phenotypes. / Støy, Julie; Kampmann, Ulla; Mengel, Annette; Magnusson, Nils E; Jessen, Niels; Grarup, Niels; Rungby, Jørgen; Stødkilde-Jørgensen, Hans; Brandslund, Ivan; Christensen, Cramer; Hansen, Torben; Pedersen, Oluf; Møller, Niels.

    In: BMJ open diabetes research & care, Vol. 3, No. 1, e000095, 2015, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Genome-wide association studies of human adiposity: Zooming in on synapses. / Sandholt, Camilla H.; Grarup, Niels; Pedersen, Oluf; Hansen, Torben.

    In: Molecular and Cellular Endocrinology, Vol. 418, No. Part 2, 2015, p. 90-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Obesity Beige adipocytes-will they beat obesity?. / Sandholt, Camilla H.; Pedersen, Oluf.

    In: Nature Reviews Endocrinology, Vol. 11, No. 12, 2015, p. 694-696.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood. / Rönn, Tina; Volkov, Petr; Gillberg, Linn; Kokosar, Milana; Perfilyev, Alexander; Jacobsen, Anna Louisa; Jørgensen, Sine W; Brøns, Charlotte; Jansson, Per-Anders; Eriksson, Karl-Fredrik; Pedersen, Oluf; Hansen, Torben; Groop, Leif; Stener-Victorin, Elisabet; Vaag, Allan; Nilsson, Emma; Ling, Charlotte.

    In: Human Molecular Genetics, Vol. 24, No. 13, 01.07.2015, p. 3792-813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans. / Pant, Sameer Dinkar; Karlskov-Mortensen, Peter; Jacobsen, Mette Juul; Cirera Salicio, Susanna; Kogelman, Lisette; Bruun, Camilla Vibeke Sichlau; Mark, Thomas; Jørgensen, Claus Bøttcher; Grarup, Niels; Appel, Emil Vincent Rosenbaum; Galjatovic, Ehm A. A.; Hansen, Torben; Pedersen, Oluf Borbye; Guerin, Maryse; Huby, Thierry; Lesnik, Philipppe; Meuwissen, Theo H. E.; Kadarmideen, Haja; Fredholm, Merete.

    In: PLOS ONE, Vol. 10, No. 9, e0137356, 08.09.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Insulin resistance as a physiological defense against metabolic stress : implications for the management of subsets of type 2 diabetes. / Nolan, Christopher J; Ruderman, Neil B; Kahn, Steven E; Pedersen, Oluf; Prentki, Marc.

    In: Diabetes, Vol. 64, No. 3, 03.2015, p. 673-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress : Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686. / Nolan, Christopher J; Ruderman, Neil B; Kahn, Steven E; Pedersen, Oluf; Prentki, Marc.

    In: Diabetes, Vol. 64, No. 10, 2015, p. e38-9.

    Research output: Contribution to journalComment/debateResearchpeer-review

  13. Published

    Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren : a prevalence study. / Mor, A; Antonsen, S; Kahlert, J; Holsteen, V; Jørgensen, S.; Holm-Pedersen, J; Sørensen, H T; Pedersen, Oluf Borbye; Ehrenstein, V.

    In: International journal of obesity (2005), Vol. 39, No. 10, 2015, p. 1450-1455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Uncovering the genetic history of the present-day greenlandic population. / Moltke, Ida; Fumagalli, Matteo; Korneliussen, Thorfinn Sand; Crawford, Jacob E; Bjerregaard, Peter; Jørgensen, Marit E; Grarup, Niels; Gulløv, Hans Christian; Linneberg, Allan René; Pedersen, Oluf Borbye; Hansen, Torben; Nielsen, Rasmus; Albrechtsen, Anders.

    In: American Journal of Human Genetics, Vol. 96, No. 1, 2015, p. 54-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism. / Mikkelsen, Kristian H; Frost, Morten; Bahl, Martin I; Licht, Tine R; Jensen, Ulrich S; Rosenberg, Jacob; Pedersen, Oluf; Hansen, Torben; Rehfeld, Jens F; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K.

    In: PLOS ONE, Vol. 10, No. 11, e0142352, 12.11.2015, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus. / Mahajan, Anubha; Sim, Xueling; Ng, Hui Jin; Manning, Alisa; Rivas, Manuel A; Highland, Heather M; Locke, Adam E; Grarup, Niels; Im, Hae Kyung; Cingolani, Pablo; Flannick, Jason; Fontanillas, Pierre; Fuchsberger, Christian; Gaulton, Kyle J; Teslovich, Tanya M; Rayner, N William; Robertson, Neil R; Beer, Nicola L; Rundle, Jana K; Bork-Jensen, Jette; Ladenvall, Claes; Blancher, Christine; Buck, David; Buck, Gemma; Burtt, Noël P; Gabriel, Stacey; Gjesing, Anette Marianne Prior; Groves, Christopher J; Hollensted, Mette; Huyghe, Jeroen R; Jackson, Anne U; Jun, Goo; Justesen, Johanne Marie; Mangino, Massimo; Murphy, Jacquelyn; Neville, Matt; Onofrio, Robert; Small, Kerrin S; Stringham, Heather M; Syvänen, Ann-Christine; Trakalo, Joseph; Abecasis, Goncalo; Bell, Graeme I; Blangero, John; Cox, Nancy J; Duggirala, Ravindranath; Linneberg, Allan; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; T2D-GENES consortium and GoT2D consortium.

    In: P L o S Genetics, Vol. 11, No. 1, e1004876, 01.2015, p. 1-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Asthma in patients with psoriasis. / Lønnberg, A S; Skov, Lone; Skytthe, A; Kyvik, K O; Pedersen, O B; Meteran, Howraman; Backer, V; Thomsen, S F.

    In: British Journal of Dermatology, 2015, p. 1660-1661.

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published

    Reference values for serum total adiponectin in healthy non-obese children and adolescents. / Lausten-Thomsen, Ulrik; Christiansen, Michael; Fonvig, Cilius Esmann; Trier, Cæcilie; Pedersen, Oluf; Hansen, Torben; Holm, Jens-Christian.

    In: Clinica Chimica Acta, Vol. 450, 23.10.2015, p. 11-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Intake of macro- and micronutrients in Danish vegans. / Kristensen, Nadja B; Madsen, Mia L; Hansen, Tue H; Allin, Kristine H; Hoppe, Camilla; Fagt, Sisse; Lausten, Mia S; Gøbel, Rikke J; Vestergaard, Henrik; Hansen, Torben; Pedersen, Oluf.

    In: Nutrition Journal, Vol. 14, No. 1, 115, 30.10.2015, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. / Kato, Norihiro; Loh, Marie; Takeuchi, Fumihiko; Verweij, Niek; Wang, Xu; Zhang, Weihua; Kelly, Tanika N; Saleheen, Danish; Lehne, Benjamin; Mateo Leach, Irene; Drong, Alexander W; Abbott, James; Wahl, Simone; Tan, Sian-Tsung; Scott, William R; Campanella, Gianluca; Chadeau-Hyam, Marc; Afzal, Uzma; Ahluwalia, Tarun Veer Singh; Bonder, Marc Jan; Chen, Peng; Dehghan, Abbas; Edwards, Todd L; Esko, Tõnu; Go, Min Jin; Harris, Sarah E; Hartiala, Jaana; Kasela, Silva; Kasturiratne, Anuradhani; Khor, Chiea-Chuen; Kleber, Marcus E; Li, Huaixing; Mok, Zuan Yu; Nakatochi, Masahiro; Sapari, Nur Sabrina; Saxena, Richa; Stewart, Alexandre F R; Stolk, Lisette; Tabara, Yasuharu; Teh, Ai Ling; Wu, Ying; Wu, Jer-Yuarn; Grarup, Niels; Justesen, Johanne M; Sparsø, Thomas Hempel; Hansen, Torben; Jørgensen, Torben; Linneberg, Allan; Pedersen, Oluf; Sørensen, Thorkild I A; BIOS Consortium.

    In: Nature Genetics, Vol. 47, No. 11, 2015, p. 1282-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population. / Justesen, Johanne M; Allin, Kristine H; Sandholt, Camilla H; Borglykke, Anders; Krarup, Nikolaj Thure; Grarup, Niels; Linneberg, Allan; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Circulation. Cardiovascular genetics, Vol. 8, 24.02.2015, p. 465-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women. / Iepsen, Eva Pers Winning; Lundgren, Julie Rehné; Hartmann, Bolette; Pedersen, Oluf; Hansen, Torben; Jørgensen, Niklas R; Jensen, Jens-Erik Beck; Holst, Jens J; Madsbad, Sten; Torekov, Signe Sørensen.

    In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 8, 2015, p. 2909 –2917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. / Iepsen, E W; Lundgren, J; Dirksen, C; Jensen, J-Eb; Pedersen, O; Hansen, T; Madsbad, S; Holst, J J; Torekov, S S.

    In: International journal of obesity (2005), Vol. 39, No. 5, 2015, p. 834-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes : a case-control study. / Hollensted, Mette; Ahluwalia, Tarun Veer Singh; Have, Christian Theil; Grarup, Niels; Fonvig, Cilius Esmann; Nielsen, Tenna Ruest Haarmark; Trier, Cæcilie; Paternoster, Lavinia; Pedersen, Oluf; Holm, Jens-Christian; Sørensen, Thorkild I A; Hansen, Torben.

    In: BMC Medical Genetics, Vol. 16, 105, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes. / Hansen, Tue Haldor; Vestergaard, Henrik; Jørgensen, Torben; Jørgensen, Marit Eika; Lauritzen, Torsten; Brandslund, Ivan; Christensen, Cramer; Pedersen, Oluf Borbye; Hansen, Torben; Gjesing, Anette Marianne Prior.

    In: BMC Medical Genetics, Vol. 16, 17, 20.03.2015, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

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