Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes. / Ahluwalia, Tarun Veer Singh; Allin, Kristine Højgaard; Sandholt, Camilla Helene; Sparsø, Thomas Hempel; Jørgensen, Marit Eika; Rowe, Michael; Christensen, Cramer; Brandslund, Ivan; Lauritzen, Torsten; Linneberg, Allan; Husemoen, Lise-Lotte; Jørgensen, Torben; Hansen, Torben; Grarup, Niels; Pedersen, Oluf.

    In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 4, 04.2015, p. E664-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    MECHANISMS IN ENDOCRINOLOGY : Gut microbiota in patients with type 2 diabetes mellitus. / Allin, Kristine H.; Nielsen, Trine; Pedersen, Oluf.

    In: European Journal of Endocrinology, Vol. 172, No. 4, 2015, p. R167-R177.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes. / Balslev-Harder, Marie; Appel, Emil Vincent Rosenbaum; Grarup, Niels; Gjesing, Anette Marianne Prior; Ahluwalia, Tarun Veer Singh; Jørgensen, Torben; Christensen, Cramer; Brandslund, Ivan; Linneberg, Allan; Sørensen, Thorkild I A; Pedersen, Oluf; Hansen, Torben.

    In: PLOS ONE, Vol. 10, No. 3, e0120890, 2015, p. 1-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. / Besenbacher, Søren; Liu, Siyang; Gonzalez-Izarzugaza, Jose Maria; Grove, Jakob; Belling, Kirstine G; Bork-Jensen, Jette; Huang, Shujia; Als, Thomas Damm; Li, Shengting; Yadav, Rachita; Rubio García, Arcadio; Lescai, Francesco; Demontis, Ditte; Rao, Junhua; Ye, Weijian; Mailund, Thomas; Møllegaard Friborg, Rune; Pedersen, Christian N. S.; Xu, Ruiqi; Sun, Jihua; Liu, Hao; Wang, Ou; Cheng, Xiaofang; Flores, David; Rydza, Emil Karol; Rapacki, Kristoffer; Sørensen, John Damm; Chmura, Piotr Jaroslaw; Westergaard, David; Dworzynski, Piotr; Sørensen, Thorkild I. A.; Lund, Ole; Hansen, Torben; Xu, Xun; Li, Ning; Bolund, Lars; Pedersen, Oluf; Eiberg, Hans; Krogh, Anders; Børglum, Anders D.; Brunak, Søren; Kristiansen, Karsten; Schierup, Mikkel H; Wang, Jun; Gupta, Ramneek; Villesen, Palle; Rasmussen, Simon.

    In: Nature Communications, Vol. 6, 5969, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity : a population-based study. / Bonfils, Linéa; Ellervik, Christina; Friedrich, Nele; Linneberg, Allan; Sandholt, Camilla H.; Jørgensen, Marit E; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Allin, Kristine H.

    In: Diabetologia, Vol. 58, No. 3, 2015, p. 523-533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Dietary modulation of the gut microbiota - a randomised controlled trial in obese postmenopausal women. / Brahe, Lena Kirchner; Le Chatelier, Emmanuelle; Prifti, Edi; Pons, Nicolas; Kennedy, Sean; Blædel, Trine; Håkansson, Janet; Dalsgaard, Trine Kastrup; Hansen, Torben; Pedersen, Oluf Borbye; Astrup, Arne; Ehrlich, S Dusko; Larsen, Lesli Hingstrup.

    In: British Journal of Nutrition, Vol. 114, No. 3, 2015, p. 406-417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Specific gut microbiota features and metabolic markers in postmenopausal women with obesity. / Brahe, Lena Kirchner; Le Chatelier, E; Prifti, E; Pons, N; Kennedy, S; Hansen, Torben; Pedersen, Oluf Borbye; Astrup, Arne; Ehrlich, S D; Larsen, Lesli Hingstrup.

    In: Nutrition and Diabetes, Vol. 5, e159, 15.05.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants. / Dashti, Hassan S; Follis, Jack L; Smith, Caren E; Tanaka, Toshiko; Cade, Brian E; Gottlieb, Daniel J; Hruby, Adela; Jacques, Paul F; Lamon-Fava, Stefania; Richardson, Kris; Saxena, Richa; Scheer, Frank A J L; Kovanen, Leena; Bartz, Traci M; Perälä, Mia-Maria; Jonsson, Anna Elisabet; Frazier-Wood, Alexis C; Kalafati, Ioanna-Panagiota; Mikkilä, Vera; Partonen, Timo; Lemaitre, Rozenn N; Lahti, Jari; Hernandez, Dena G; Toft, Ulla; Johnson, W Craig; Kanoni, Stavroula; Raitakari, Olli T; Perola, Markus; Psaty, Bruce M; Ferrucci, Luigi; Grarup, Niels; Highland, Heather M; Rallidis, Loukianos; Kähönen, Mika; Havulinna, Aki S; Siscovick, David S; Räikkönen, Katri; Jørgensen, Torben; Rotter, Jerome I; Deloukas, Panos; Viikari, Jorma S A; Mozaffarian, Dariush; Linneberg, Allan; Seppälä, Ilkka; Hansen, Torben; Salomaa, Veikko; Gharib, Sina A; Eriksson, Johan G; Bandinelli, Stefania; Pedersen, Oluf; Rich, Stephen S; Dedoussis, George; Lehtimäki, Terho; Ordovás, José M.

    In: The American Journal of Clinical Nutrition, Vol. 101, No. 1, 01.2015, p. 135-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex : The ADDITION-PRO Study. Diabetes 2015;64:2513–2525. / Ferch, Kristine; Torekov, Signe S.; Vistisen, Dorte; Johansen, Nanna B; Witte, Daniel R; Jonsson, Anna; Pedersen, Oluf; Hansen, Torben; Lauritzen, Torsten; Sandbek, Annelli; Holst, Jens Juul; Jørgensen, Marit E.

    In: Diabetes, Vol. 64, No. 9, 01.09.2015, p. e30-e31.

    Research output: Contribution to journalComment/debateResearchpeer-review

  10. Published

    1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents. / Fonvig, Cilius Esmann; Chabanova, Elizaveta; Andersson, Ehm Astrid; Ohrt, Johanne Dam; Pedersen, Oluf; Hansen, Torben; Thomsen, Henrik S; Holm, Jens-Christian.

    In: PLOS ONE, Vol. 10, No. 8, e0135018, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle. / Fonvig, Cilius Esmann; Chabanova, Elizaveta; Ohrt, Johanne Dam; Nielsen, Louise Aas; Pedersen, Oluf; Hansen, Torben; Thomsen, Henrik S; Holm, Jens-Christian.

    In: B M C Pediatrics, Vol. 15, 196, 2015, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. / Forslund, Kristoffer; Hildebrand, Falk; Nielsen, Trine; Falony, Gwen; Le Chatelier, Emmanuelle; Sunagawa, Shinichi; Prifti, Edi; Vieira-Silva, Sara; Gudmundsdottir, Valborg; Pedersen, Helle Krogh; Arumugam, Manimozhiyan; Kristiansen, Karsten; Yvonne Voigt, Anita; Vestergaard, Henrik; Hercog, Rajna; Igor Costea, Paul; Roat Kultima, Jens; Li, Junhua; Jørgensen, Torben; Levenez, Florence; Dore, Joël; Nielsen, Henrik Bjørn; Brunak, Søren; Raes, Jeroen; Hansen, Torben; Wang, Jun; Dusko Ehrlich, S.; Bork, Peer; Pedersen, Oluf Borbye.

    In: Nature, Vol. 528, No. 7581, 2015, p. 262-266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Greenlandic Inuit show genetic signatures of diet and climate adaptation. / Fumagalli, Matteo; Moltke, Ida; Grarup, Niels; Racimo, Fernando; Bjerregaard, Peter; Jørgensen, Marit E.; Korneliussen, Thorfinn Sand; Gerbault, Pascale; Skotte, Line; Linneberg, Allan René; Christensen, Cramer; Brandslund, Ivan; Jørgensen, Torben; Huerta-Sánchez, Emilia; Schmidt, Erik Berg; Pedersen, Oluf Borbye; Hansen, Torben; Albrechtsen, Anders; Nielsen, Rasmus.

    In: Science (New York, N.Y.), Vol. 349, No. 6254, 2015, p. 1343-1347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex : The ADDITION-PRO Study. / Færch, Kristine; Torekov, Signe S; Vistisen, Dorte; Johansen, Nanna B; Witte, Daniel R; Jonsson, Anna; Pedersen, Oluf; Hansen, Torben; Lauritzen, Torsten; Sandbæk, Annelli; Holst, Jens Juul; Jørgensen, Marit E.

    In: Diabetes, Vol. 64, 07.2015, p. 2513-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. / Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; Mahajan, Anubha; Locke, Adam; William Rayner, N; Robertson, Neil; Scott, Robert A; Prokopenko, Inga; Scott, Laura J; Green, Todd; Sparso, Thomas; Thuillier, Dorothee; Yengo, Loic; Grallert, Harald; Wahl, Simone; Frånberg, Mattias; Strawbridge, Rona J; Kestler, Hans; Chheda, Himanshu; Eisele, Lewin; Gustafsson, Stefan; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Qi, Lu; Karssen, Lennart C; van Leeuwen, Elisabeth M; Willems, Sara M; Li, Man; Chen, Han; Fuchsberger, Christian; Kwan, Phoenix; Ma, Clement; Linderman, Michael; Lu, Yingchang; Thomsen, Soren K; Rundle, Jana K; Grarup, Niels; Have, Christian T; Jonsson, Anna; Jørgensen, Marit Eika; Jørgensen, Torben; Linneberg, Allan; Storm, Petter; Njølstad, Inger; Hansen, Torben; Pedersen, Oluf; Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium.

    In: Nature Genetics, Vol. 47, No. 12, 12.2015, p. 1415-25, 3 unpag. pages.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval. / Ghouse, Jonas; Have, Christian Theil; Weeke, Peter; Nielsen, Jonas Bille; Ahlberg, Gustav; Balslev-Harder, Marie; Appel, Emil Vincent; Skaaby, Tea; Olesen, Søren-Peter; Grarup, Niels; Linneberg, Allan; Pedersen, Oluf; Haunsø, Stig; Hastrup Svendsen, Jesper; Hansen, Torben; Kanters, Jørgen Kim; Salling Olesen, Morten.

    In: European Heart Journal, Vol. 36, No. 37, 01.10.2015, p. 2523-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data. / Gjesing, Anette Marianne Prior; Ribel-Madsen, Rasmus; Harder, Marie Neergaard; Eiberg, Hans; Grarup, Niels; Jørgensen, Torben; Ekstrøm, Claus T; Pedersen, Oluf; Hansen, Torben.

    In: Diabetologia, Vol. 58, No. 5, 05.2015, p. 1006-1012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease. / Gretarsdottir, Solveig; Helgason, Hannes; Helgadottir, Anna; Sigurdsson, Asgeir; Thorleifsson, Gudmar; Magnusdottir, Audur; Oddsson, Asmundur; Steinthorsdottir, Valgerdur; Rafnar, Thorunn; de Graaf, Jacqueline; Daneshpour, Maryam S; Hedayati, Mehdi; Azizi, Fereidoun; Grarup, Niels; Jørgensen, Torben; Vestergaard, Henrik; Hansen, Torben; Eyjolfsson, Gudmundur; Sigurdardottir, Olof; Olafsson, Isleifur; Kiemeney, Lambertus A; Pedersen, Oluf; Sulem, Patrick; Thorgeirsson, Gudmundur; Gudbjartsson, Daniel F; Holm, Hilma; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: P L o S Genetics, Vol. 11, No. 9, e1005379, 09.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A glycogene mutation map for discovery of diseases of glycosylation. / Hansen, Lars; Lind-Thomsen, Allan; Joshi, Hiren J; Pedersen, Nis Borbye; Have, Christian Theil; Kong, Yun; Wang, Shengjun; Sparso, Thomas; Grarup, Niels; Vester-Christensen, Malene Bech; Schjoldager, Katrine; Freeze, Hudson H; Hansen, Torben; Pedersen, Oluf; Henrissat, Bernard; Mandel, Ulla; Clausen, Henrik; Wandall, Hans H; Bennett, Eric P.

    In: Glycobiology, Vol. 25, No. 2, 2015, p. 211-224.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes. / Hansen, Tue Haldor; Vestergaard, Henrik; Jørgensen, Torben; Jørgensen, Marit Eika; Lauritzen, Torsten; Brandslund, Ivan; Christensen, Cramer; Pedersen, Oluf Borbye; Hansen, Torben; Gjesing, Anette Marianne Prior.

    In: BMC Medical Genetics, Vol. 16, 17, 20.03.2015, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The gut microbiome in cardio-metabolic health. / Hansen, Tue Haldor; Gøbel, Rikke J; Hansen, Torben; Pedersen, Oluf.

    In: Genome Medicine, Vol. 7, 33, 2015, p. 1-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes : a case-control study. / Hollensted, Mette; Ahluwalia, Tarun Veer Singh; Have, Christian Theil; Grarup, Niels; Fonvig, Cilius Esmann; Nielsen, Tenna Ruest Haarmark; Trier, Cæcilie; Paternoster, Lavinia; Pedersen, Oluf; Holm, Jens-Christian; Sørensen, Thorkild I A; Hansen, Torben.

    In: BMC Medical Genetics, Vol. 16, 105, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. / Iepsen, E W; Lundgren, J; Dirksen, C; Jensen, J-Eb; Pedersen, O; Hansen, T; Madsbad, S; Holst, J J; Torekov, S S.

    In: International journal of obesity (2005), Vol. 39, No. 5, 2015, p. 834-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women. / Iepsen, Eva Pers Winning; Lundgren, Julie Rehné; Hartmann, Bolette; Pedersen, Oluf; Hansen, Torben; Jørgensen, Niklas R; Jensen, Jens-Erik Beck; Holst, Jens J; Madsbad, Sten; Torekov, Signe Sørensen.

    In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 8, 2015, p. 2909 –2917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population. / Justesen, Johanne M; Allin, Kristine H; Sandholt, Camilla H; Borglykke, Anders; Krarup, Nikolaj Thure; Grarup, Niels; Linneberg, Allan; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Circulation. Cardiovascular genetics, Vol. 8, 24.02.2015, p. 465-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 919113