Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2013
  2. Published

    Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes. / Lohmueller, Kirk E.; Sparsø, Thomas Hempel; Li, Qibin; Galijatovic, Ehm Astrid Andersson; Korneliussen, Thorfinn Sand; Albrechtsen, Anders; Banasik, Karina; Grarup, Niels; Hallgrimsdottir, Ingileif; Kiil, Kristoffer; Oskari Kilpeläinen, Tuomas; Krarup, Nikolaj Thure; Pers, Tune Hannes; Sanchez, Gaston; Hu, Youna; DeGiorgio, Michael; Jørgensen, Torben; Sandbæk, Annelli; Lauritzen, Torsten ; Brunak, Søren; Kristiansen, Karsten; Li, Yingrui; Hansen, Torben; Wang, Jun; Nielsen, Rasmus; Pedersen, Oluf Borbye.

    In: American Journal of Human Genetics, Vol. 93, No. 6, 05.12.2013, p. 1072-1086.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity. / Dimas, Antigone S; Lagou, Vasiliki; Barker, Adam; Knowles, Joshua W; Mägi, Reedik; Hivert, Marie-France; Benazzo, Andrea; Rybin, Denis; Jackson, Anne U; Stringham, Heather M; Song, Ci; Fischer-Rosinsky, Antje; Boesgaard, Trine Welløv; Grarup, Niels; Abbasi, Fahim A; Assimes, Themistocles L; Hao, Ke; Yang, Xia; Lecoeur, Cécile; Barroso, Inês; Bonnycastle, Lori L; Böttcher, Yvonne; Bumpstead, Suzannah; Chines, Peter S; Erdos, Michael R; Graessler, Jurgen; Kovacs, Peter; Morken, Mario A; Narisu, Narisu; Payne, Felicity; Stancakova, Alena; Swift, Amy J; Tönjes, Anke; Bornstein, Stefan R; Cauchi, Stéphane; Froguel, Philippe; Meyre, David; Schwarz, Peter E H; Häring, Hans-Ulrich; Smith, Ulf; Boehnke, Michael; Bergman, Richard N; Collins, Francis S; Mohlke, Karen L; Tuomilehto, Jaakko; Quertemous, Thomas; Lind, Lars; Hansen, Torben; Pedersen, Oluf; Walker, Mark; on behalf of the MAGIC investigators.

    In: Diabetes, Vol. 63, No. 6, 02.12.2013, p. 2158-2171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Gut microbiota may have influence on glucose and lipid metabolism. / Mikkelsen, Kristian Hallundbæk; Nielsen, Morten Frost; Tvede, Michael; Hansen, Torben; Pedersen, Oluf Borbye; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip Krag.

    In: Ugeskrift for Laeger, Vol. 175, No. 46, 11.11.2013, p. 2785-2788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes. / Snogdal, Lena Sønder; Grarup, Niels; Banasik, Karina; Wod, Mette; Jørgensen, Torben; Witte, Daniel R; Lauritzen, Torsten; Nielsen, Aneta Aleksandra; Brandslund, Ivan; Christensen, Cramer; Pedersen, Oluf; Yderstræde, Knud Bonnet; Beck-Nielsen, Henning; Henriksen, Jan Erik; Hansen, Torben; Højlund, Kurt.

    In: BMC Medical Genetics, Vol. 14, No. 1, 25.10.2013, p. 113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic beta-cell function over 5 years of follow-up. / Galijatovic, Ehm Astrid Andersson; Allin, Kristine H; Sandholt, Camilla H; Borglykke, Anders; Lau, Cathrine J; Ribel-Madsen, Rasmus; Sparsø, Thomas; Justesen, Johanne M; Harder, Marie N; Jørgensen, Marit E; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 62, No. 10, 08.07.2013, p. 3610.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes. / Yaghootkar, Hanieh; Lamina, Claudia; Scott, Robert A; Dastani, Zari; Hivert, Marie-France; Warren, Liling L; Stancáková, Alena; Buxbaum, Sarah G; Lyytikäinen, Leo-Pekka; Henneman, Peter; Wu, Ying; Cheung, Chloe Yy; Pankow, James S; Jackson, Anne U; Gustafsson, Stefan; Zhao, Jing Hua; Ballantyne, Christie M; Xie, Weijia; Bergman, Richard N; Boehnke, Michael; El Bouazzaoui, Fatiha; Collins, Francis S; Dunn, Sandra H; Dupuis, Josee; Forouhi, Nita G; Gillson, Christopher; Hattersley, Andrew T; Hong, Jaeyoung; Kähönen, Mika; Kuusisto, Johanna; Kedenko, Lyudmyla; Kronenberg, Florian; Doria, Alessandro; Assimes, Themistocles L; Ferrannini, Ele; Hansen, Torben; Hao, Ke; Häring, Hans; Knowles, Joshua W; Lindgren, Cecilia M; Nolan, John J; Paananen, Jussi; Pedersen, Oluf; Quertermous, Thomas; Smith, Ulf; Lehtimäki, Terho; Liu, Ching-Ti; Loos, Ruth Jf; McCarthy, Mark I; Morris, Andrew D; the GENESIS consortium.

    In: Diabetes, Vol. 62, No. 10, 08.07.2013, p. 3589.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Gene × physical activity interactions in obesity : combined analysis of 111,421 individuals of European ancestry. / Ahmad, Shafqat; Rukh, Gull; Varga, Tibor V; Ali, Ashfaq; Kurbasic, Azra; Shungin, Dmitry; Ericson, Ulrika; Koivula, Robert W; Chu, Audrey Y; Rose, Lynda M; Ganna, Andrea; Qi, Qibin; Stančáková, Alena; Sandholt, Camilla H; Elks, Cathy E; Curhan, Gary; Jensen, Majken K; Tamimi, Rulla M; Allin, Kristine H; Jørgensen, Torben; Brage, Soren; Langenberg, Claudia; Aadahl, Mette; Grarup, Niels; Linneberg, Allan; Paré, Guillaume; Magnusson, Patrik K E; Pedersen, Nancy L; Boehnke, Michael; Hamsten, Anders; Mohlke, Karen L; Pasquale, Louis T; Pedersen, Oluf; Scott, Robert A; Ridker, Paul M; Ingelsson, Erik; Laakso, Markku; Hansen, Torben; Qi, Lu; Wareham, Nicholas J; Chasman, Daniel I; Hallmans, Göran; Hu, Frank B; Renström, Frida; Orho-Melander, Marju; Franks, Paul W; InterAct Consortium.

    In: P L o S Genetics (Online), Vol. 9, No. 7, 07.2013, p. e1003607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The effect of GWAS identified BMI loci on changes in body weight among middle-aged danes during a five year period. / Sandholt, Camilla Helene; Allin, Kristine Højgaard; Toft, U; Borglykke, A; Ribel-Madsen, Rasmus; Sparsø, Thomas Hempel; Justesen, Johanne Marie; Harder, Marie Neergaard; Jørgensen, Torben; Hansen, Torben; Pedersen, O.

    In: Obesity, Vol. 22, No. 3, 26.06.2013, p. 901-908.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Insulin resistance and impaired pancreatic beta-cell function in adult offspring of women with diabetes in pregnancy. / Kelstrup, Louise; Damm, Peter; Mathiesen, Elisabeth R; Hansen, Torben; Vaag, Allan A; Pedersen, Oluf; Clausen, Tine D.

    In: The Journal of clinical endocrinology and metabolism, Vol. 98, No. 9, 24.06.2013, p. 3793-3801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. / Xie, Weijia; Wood, Andrew R; Lyssenko, Valeriya; Weedon, Michael N; Knowles, Joshua W; Alkayyali, Sami; Assimes, Themistocles L; Quertermous, Thomas; Abbasi, Fahim; Paananen, Jussi; Häring, Hans; Hansen, Torben; Pedersen, Oluf; Smith, Ulf; Laakso, Markku; Dekker, Jacqueline M; Nolan, John J; Groop, Leif; Ferrannini, Ele; Adam, Klaus-Peter; Gall, Walter E; Frayling, Timothy M; Walker, Mark; MAGIC Investigators.

    In: Diabetes, Vol. 62, No. 6, 06.2013, p. 2141-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. / 't Hart, Leen M; Fritsche, Andreas; Nijpels, Giel; van Leeuwen, Nienke; Donnelly, Louise A; Dekker, Jacqueline M; Alssema, Marjan; Fadista, Joao; Carlotti, Françoise; Gjesing, Anette P; Palmer, Colin N A; van Haeften, Timon W; Herzberg-Schäfer, Silke A; Simonis-Bik, Annemarie M C; Houwing-Duistermaat, Jeanine J; Helmer, Quinta; Deelen, Joris; Guigas, Bruno; Hansen, Torben; Machicao, Fausto; Willemsen, Gonneke; Heine, Robert J; Kramer, Mark; Holst, Jens Juul; de Koning, Eelco J P; Häring, Hans-Ulrich; Pedersen, Oluf; Groop, Leif; de Geus, Eco J C; Slagboom, P Eline; Boomsma, Dorret I; Eekhoff, Elisabeth M W; Pearson, Ewan R; Diamant, Michaela.

    In: Diabetes, Vol. 62, No. 9, 14.05.2013, p. 3275-3281.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cohort Profile : The Health2006 cohort, Research Centre for Prevention and Health. / Thuesen, Betina Heinsbæk; Cerqueira, Charlotte; Aadahl, Mette; Ebstrup, Jeanette Frost; Toft, Ulla; Thyssen, Jacob P; Fenger, Runa Vavia; Hersoug, Lars-Georg; Elberling, Jesper; Pedersen, Oluf; Hansen, Torben; Johansen, Jeanne Duus; Jørgensen, Torben; Linneberg, Allan René.

    In: International Journal of Epidemiology, Vol. 43, No. 2, 24.04.2013, p. 568-575.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Type 2 Diabetes Risk Alleles Near BCAR1 and in ANK1 Associate With Decreased ß-Cell Function Whereas Risk Alleles Near ANKRD55 and GRB14 Associate With Decreased Insulin Sensitivity in the Danish Inter99 Cohort. / Harder, Marie N; Ribel-Madsen, Rasmus; Justesen, Johanne M; Sparsø, Thomas; Galijatovic, Ehm Astrid Andersson; Grarup, Niels; Jørgensen, Torben; Linneberg, Allan; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 98, No. 4, 01.04.2013, p. 801-806.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mutations in HNF1A result in marked alterations of plasma glycan profile. / Thanabalasingham, Gaya; Huffman, Jennifer E; Kattla, Jayesh J; Novokmet, Mislav; Rudan, Igor; Gloyn, Anna L; Hayward, Caroline; Adamczyk, Barbara; Reynolds, Rebecca M; Muzinic, Ana; Hassanali, Neelam; Pucic, Maja; Bennett, Amanda J; Essafi, Abdelkader; Polasek, Ozren; Mughal, Saima A; Redzic, Irma; Primorac, Dragan; Zgaga, Lina; Kolcic, Ivana; Hansen, Torben; Gasperikova, Daniela; Tjora, Erling; Strachan, Mark W J; Nielsen, Trine; Stanik, Juraj; Klimes, Iwar; Pedersen, Oluf B; Njølstad, Pål R; Wild, Sarah H; Gyllensten, Ulf; Gornik, Olga; Wilson, James F; Hastie, Nicholas D; Campbell, Harry; McCarthy, Mark I; Rudd, Pauline M; Owen, Katharine R; Lauc, Gordan; Wright, Alan F.

    In: Diabetes, Vol. 62, No. 4, 04.2013, p. 1329-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes. / Bonnefond, A; Yengo, L; Philippe, J; Dechaume, A; Ezzidi, I; Vaillant, E; Gjesing, A P; Andersson, E A; Czernichow, S; Hercberg, S; Hadjadj, S; Charpentier, G; Lantieri, O; Balkau, B; Marre, M; Pedersen, O; Hansen, T; Froguel, P; Vaxillaire, M.

    In: Diabetologia, Vol. 56, No. 3, 03.2013, p. 492-496.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease. / Vazquez-Chantada, Mercedes; Gonzalez-Lahera, Aintzane; Martinez-Arranz, Ibon; Garcia-Monzon, Carmelo; Regueiro, Manuela M; Garcia-Rodriguez, Juan L; Schlangen, Karin A; Mendibil, Iñaki; Rodriguez-Ezpeleta, Naiara; Lozano, Juan J; Banasik, Karina; Justesen, Johanne M; Jørgensen, Torben; Witte, Daniel R; Lauritzen, Torsten; Hansen, Torben; Pedersen, Oluf; Veyrie, Nicolas; Clement, Karine; Tordjman, Joan; Tran, Albert; Le Marchand-Brustel, Yannik; Buque, Xabier; Aspichueta, Patricia; Echevarria-Uraga, Jose J; Martin-Duce, Antonio; Caballeria, Joan; Gual, Philippe; Castro, Azucena; Mato, Jose M; Martinez-Chantar, Maria L; Aransay, Ana M.

    In: Hepatology, Vol. 57, No. 2, 02.2013, p. 505-514.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications? / Bonnefond, Amélie; Saulnier, Pierre-Jean; Stathopoulou, Maria G; Grarup, Niels; Ndiaye, Ndeye Coumba; Roussel, Ronan; Nezhad, Mohsen Azimi; Dechaume, Aurélie; Lantieri, Olivier; Hercberg, Serge; Lauritzen, Torsten; Balkau, Beverley; El-Sayed Moustafa, Julia S; Hansen, Torben; Pedersen, Oluf; Froguel, Philippe; Charpentier, Guillaume; Marre, Michel; Hadjadj, Samy; Visvikis-Siest, Sophie.

    In: P L o S One, Vol. 8, No. 2, 02.2013, p. e55921.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples. / Jiang, Rong; Brummett, Beverly H; Hauser, Elizabeth R; Babyak, Michael A; Siegler, Ilene C; Singh, Abanish; Astrup, Arne; Pedersen, Oluf; Hansen, Torben; Holst, Claus; Sørensen, Thorkild I A; Williams, Redford B.

    In: Biological Psychology, Vol. 93, No. 1, 2013, p. 184-189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Correction : Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease - Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants. / Borglykke, Anders; Grarup, Niels; Sparsø, Thomas Hempel; Linneberg, Allan René; Fenger, Mogens; Jeppesen, Jørgen; Hansen, Torben; Pedersen, Oluf Borbye; Jørgensen, Torben.

    In: P L o S One, Vol. 8, No. 5, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes? / Gillberg, Linn; Jacobsen, Stine; Ribel-Madsen, Rasmus; Gjesing, Anette Marianne Prior; Boesgaard, Trine W; Ling, Charlotte; Pedersen, Oluf; Hansen, Torben; Vaag, Allan.

    In: P L o S One, Vol. 8, No. 3, 2013, p. e58384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. / Albrechtsen, Anders; Grarup, Niels; Li, Y.; Sparsø, Thomas Hempel; Tian, G.; Cao, H.; Jiang, T.; Kim, S.Y.; Korneliussen, Thorfinn Sand; Li, Q.; Nie, C.; Wu, R.; Skotte, Line; Morris, A.P.; Ladenvall, C.; Cauchi, S.; Stancáková, A.; Andersen, G.; Astrup, Arne; Banasik, Karina; Bennett, A.J.; Bolund, Lars; Charpentier, G.; Chen, Y.; Dekker, J.M.; Doney, A.S.F.; Dorkhan, M.; Forsen, T.; Frayling, T.M.; Groves, C.J.; Gui, Y.; Hallmans, G.; Hattersley, A.T.; He, K.; Hitman, G.A.; Holmkvist, J.; Huang, S.; Jiang, H.; Jin, X.; Justesen, Johanne Marie; Kristiansen, Karsten; Kuusisto, J.; Lajer, M.; Lantieri, O.; Li, W.; Liang, H.; Liao, Q.; Liu, X.; Ma, T.; Ma, X.; Manijak, M.P.; Marre, M.; Mokrosinski, Jacek; Morris, A.D.; Mu, B.; Nielsen, A.A.; Nijpels, G.; Nilsson, P.; Palmer, C.N.A.; Rayner, N.W.; Renström, F.; Ribel-Madsen, Rasmus; Robertson, N.; Rolandsson, O.; Rossing, P.; Schwartz, Thue W.; Slagboom, P.E.; Sterner, M.; Tang, M.; Tarnow, L.; Tuomi, T.; Van't Riet, E.; van Leeuwen, N.; Varga, T.V.; Vestmar, Marie Aare; Walker, M.; Wang, B.; Wang, Y.; Wu, H.; Xi, F.; Yengo, L.; Yu, C.; Zhang, X.; Zhang, J.; Zhang, Q.; Zhang, W.; Zheng, H.; Zhou, Y.; Altshuler, D.; 't Hart, L.M.; Franks, P.W.; Balkau, B.; Froguel, P.; McCarthy, M.I.; Laakso, M.; Groop, L.; Christensen, C.; Brandslund, I.; Lauritzen, T.; Witte, D.R.; Linneberg, A.; Jørgensen, Torben; Hansen, Torben; Wang, Jun; Nielsen, Rasmus; Pedersen, Oluf.

    In: Diabetologia, Vol. 56, No. 2, 2013, p. 298-310.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. / Grarup, Niels; Sulem, Patrick; Sandholt, Camilla H; Thorleifsson, Gudmar; Ahluwalia, Tarun Veer Singh; Steinthorsdottir, Valgerdur; Bjarnason, Helgi; Gudbjartsson, Daniel F; Magnusson, Olafur T; Sparsø, Thomas; Albrechtsen, Anders; Kong, Augustine; Masson, Gisli; Tian, Geng; Cao, Hongzhi; Nie, Chao; Kristiansen, Karsten; Husemoen, Lise Lotte; Thuesen, Betina; Li, Yingrui; Nielsen, Rasmus; Linneberg, Allan; Olafsson, Isleifur; Eyjolfsson, Gudmundur I; Jørgensen, Torben; Wang, Jun; Hansen, Torben; Thorsteinsdottir, Unnur; Stefánsson, Kari; Pedersen, Oluf Borbye.

    In: P L o S Genetics, Vol. 9, No. 6, e1003530, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Insulin Resistance and Impaired Pancreatic β-Cell Function in Adult Offspring of Women With Diabetes in Pregnancy. / Kelstrup, Louise; Damm, Peter; Mathiesen, Elisabeth R; Hansen, Torben; Vaag, Allan A; Pedersen, Oluf Borbye; Dalsgaard Clausen, Tine.

    In: The Journal of clinical endocrinology and metabolism, Vol. 98, No. 9, 2013, p. 3793-3801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Long-term renal outcome in the Steno 2 study. / Ollgaard, J.; Persson, F.; Rossing, P.; Parving, H.-H.; Pedersen, O. B.; Gaede, P. H.

    In: Diabetologia, Vol. 56, 2013, p. S45-S46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Metagenomic species profiling using universal phylogenetic marker genes. / Sunagawa, Shinichi; Mende, Daniel R.; Zeller, Georg; Izquierdo-Carrasco, Fernando; Berger, Simon A.; Kultima, Jens Roat; Coelho, Luis Pedro; Arumugam, Manimozhiyan; Tap, Julien; Nielsen, Henrik Bjørn; Rasmussen, Simon; Brunak, Søren; Pedersen, Oluf Borbye; Guarner, Francisco; de Vos, Willem M; Wang, Jun; Li, Junhua; Doré, Joël; Ehrlich, S Dusko; Stamatakis, Alexandros; Bork, Peer.

    In: Nature Methods, Vol. 10, No. 12, 2013, p. 1196-1199.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 919113