Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. / Zeggini, Eleftheria; Scott, Laura J; Saxena, Richa; Voight, Benjamin F; Marchini, Jonathan L; Hu, Tianle; de Bakker, Paul I W; Abecasis, Gonçalo R; Almgren, Peter; Andersen, Gitte; Ardlie, Kristin; Boström, Kristina Bengtsson; Bergman, Richard N; Bonnycastle, Lori L; Borch-Johnsen, Knut; Burtt, Noël P; Chen, Hong; Chines, Peter S; Daly, Mark J; Deodhar, Parimal; Ding, Chia-Jen; Doney, Alex S F; Duren, William L; Elliott, Katherine S; Erdos, Michael R; Frayling, Timothy M; Freathy, Rachel M; Gianniny, Lauren; Grallert, Harald; Grarup, Niels; Groves, Christopher J; Guiducci, Candace; Hansen, Torben; Herder, Christian; Hitman, Graham A; Hughes, Thomas E; Isomaa, Bo; Jackson, Anne U; Jørgensen, Torben; Kong, Augustine; Kubalanza, Kari; Kuruvilla, Finny G; Kuusisto, Johanna; Langenberg, Claudia; Lango, Hana; Lauritzen, Torsten; Li, Yun; Lindgren, Cecilia M; Lyssenko, Valeriya; Wellcome Trust Case Control Consortium ; Pedersen, Oluf.

    In: Nature Genetics, Vol. 40, No. 5, 2008, p. 638-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins. / Wegner, Lise; Hussain, Meena S; Pilgaard, Kasper; Hansen, Torben; Pedersen, Oluf; Vaag, Allan; Poulsen, Inge Pernille.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 10, 2008, p. 4013-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals. / Vimaleswaran, Karani Santhanakrishnan; Luan, Jian'an; Andersen, Gitte; Muller, Y Li; Wheeler, Eleanor; Brito, Ema C; O'Rahilly, Stephen; Pedersen, Oluf; Baier, Leslie J; Knowler, William C; Barroso, Inês; Wareham, Nicholas J; Loos, Ruth J F; Franks, Paul W.

    In: Journal of Applied Physiology, Vol. 105, No. 4, 2008, p. 1352-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. / Unoki, Hiroyuki; Takahashi, Atsushi; Kawaguchi, Takahisa; Hara, Kazuo; Horikoshi, Momoko; Andersen, Gitte; Ng, Daniel P K; Holmkvist, Johan; Borch-Johnsen, Knut; Jørgensen, Torben; Sandbæk, Annelli; Lauritzen, Torsten; Hansen, Torben; Nurbaya, Siti; Tsunoda, Tatsuhiko; Kubo, Michiaki; Babazono, Tetsuya; Hirose, Hiroshi; Hayashi, Matsuhiko; Iwamoto, Yasuhiko; Kashiwagi, Atsunori; Kaku, Kohei; Kawamori, Ryuzo; Tai, E Shyong; Pedersen, Oluf; Kamatani, Naoyuki; Kadowaki, Takashi; Kikkawa, Ryuichi; Nakamura, Yusuke; Maeda, Shiro.

    In: Nature Genetics, Vol. 40, No. 9, 2008, p. 1098-1102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. / Stancáková, Alena; Pihlajamäki, Jussi; Kuusisto, Johanna; Stefan, Norbert; Fritsche, Andreas; Häring, Hans; Andreozzi, Francesco; Succurro, Elena; Sesti, Giorgio; Boesgaard, Trine Welløv; Hansen, Torben; Pedersen, Oluf; Jansson, Per Anders; Hammarstedt, Ann; Smith, Ulf; Laakso, Markku; EUGENE2 Consortium.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 5, 2008, p. 1924-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study. / Staiger, Harald; Stancáková, Alena; Zilinskaite, Jone; Vänttinen, Markku; Hansen, Torben; Marini, Maria Adelaide; Hammarstedt, Ann; Jansson, Per-Anders; Sesti, Giorgio; Smith, Ulf; Pedersen, Oluf; Laakso, Markku; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich.

    In: Diabetes, Vol. 57, No. 2, 2008, p. 514-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes (Diabetologia DOI : 10.1007/s00125-007-0865-z). / Sparsø, T.; Andersen, G.; Nielsen, T.; Burgdorf, K. S.; Gjesing, A. P.; Nielsen, A. L.; Albrechtsen, A.; Rasmussen, S. S.; Jørgensen, T.; Borch-Johnsen, K.; Sandbæk, A.; Lauritzen, T.; Madsbad, S.; Hansen, T.; Pedersen, O.

    In: Diabetologia, Vol. 51, No. 2, 01.02.2008.

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation. / Sparsø, T; Andersen, G; Albrechtsen, Anders; Jørgensen, T; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Wasson, J; Permutt, M A; Glaser, B; Madsbad, S; Pedersen, Oluf; Hansen, T.

    In: Diabetologia, Vol. 51, No. 9, 2008, p. 1646-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes. / Sandholt, Camilla Helene; Mogensen, Mette S; Borch-Johnsen, Knut; Sandbaek, Annelli; Lauritzen, Torsten; Sørensen, Thorkild I A; Hansen, Lars; Almind, Katrine; Jørgensen, Torben; Pedersen, Oluf; Hansen, Torben.

    In: PLoS ONE, Vol. 3, No. 8, 2008, p. e2872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes. / Nielsen, Trine; Burgdorf, Kristoffer Sølvsten; Grarup, Niels; Borch-Johnsen, Knut; Hansen, Torben; Jørgensen, Torben; Pedersen, Oluf; Andersen, Gitte.

    In: Journal of Hypertension, Vol. 26, No. 11, 2008, p. 2142-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes. / Lund, Søren S; Tarnow, Lise; Stehouwer, Coen D A; Schalkwijk, Casper G; Teerlink, Tom; Gram, Jørgen; Winther, Kaj; Frandsen, Merete; Smidt, Ulla M; Pedersen, Oluf; Parving, Hans-Henrik; Vaag, Allan A.

    In: European Journal of Endocrinology, Vol. 158, No. 5, 2008, p. 631-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Impact of metformin versus the prandial insulin secretagogue, repaglinide, on fasting and postprandial glucose and lipid responses in non-obese patients with type 2 diabetes. / Lund, Søren S; Tarnow, Lise; Frandsen, Merete; Smidt, Ulla M; Pedersen, Oluf; Parving, Hans-Henrik; Vaag, Allan A.

    In: European Journal of Endocrinology, Vol. 158, No. 1, 2008, p. 35-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study. / Laakso, M; Zilinskaite, J; Hansen, T; Boesgaard, T Welløv; Vänttinen, M; Stancáková, A; Jansson, P-A; Pellmé, F; Kuulasmaa, T; Hribal, M L; Sesti, G; Stefan, N; Fritsche, A; Häring, H; Pedersen, Oluf; Smith, U; EUGENE2 Consortium ; Holst, Jens Juul.

    In: Diabetologia, Vol. 51, No. 3, 2008, p. 502-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype. / Kring, Sofia Inez Iqbal; Larsen, Lesli Hingstrup; Holst, Claus; Toubro, Søren; Hansen, Torben; Astrup, Arne; Pedersen, Oluf; Sørensen, Thorkild I A.

    In: Obesity Facts, Vol. 1, No. 3, 2008, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness. / Kring, Sofia I I; Holst, Claus; Zimmermann, Esther; Jess, Tine; Berentzen, Tina; Toubro, Søren; Hansen, Torben; Astrup, Arne; Pedersen, Oluf; Sørensen, Thorkild I A.

    In: PLoS ONE, Vol. 3, No. 8, 2008, p. e2958.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy. / Jorsal, A; Tarnow, L; Lajer, M; Ek, J; Hansen, T; Pedersen, Oluf; Parving, H-H.

    In: Molecular Genetics and Metabolism, Vol. 94, No. 3, 2008, p. 347-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study. / Jess, T; Zimmermann, E; Kring, S I I; Berentzen, T; Holst, C; Toubro, Søren; Astrup, A; Hansen, T; Pedersen, O; Sørensen, Thorkild I.A.; Pedersen, Oluf.

    In: International Journal of Obesity, Vol. 32, No. 9, 2008, p. 1388-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result. / Holmkvist, J; Anthonsen, S; Wegner, L; Andersen, G; Jørgensen, T; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Pedersen, Oluf; Hansen, T.

    In: Diabetologia, Vol. 51, No. 4, 2008, p. 609-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. / Helgadottir, Anna; Thorleifsson, Gudmar; Magnusson, Kristinn P; Grétarsdottir, Solveig; Steinthorsdottir, Valgerdur; Manolescu, Andrei; Jones, Gregory T; Rinkel, Gabriel J E; Blankensteijn, Jan D; Ronkainen, Antti; Jääskeläinen, Juha E; Kyo, Yoshiki; Lenk, Guy M; Sakalihasan, Natzi; Kostulas, Konstantinos; Gottsäter, Anders; Flex, Andrea; Stefansson, Hreinn; Hansen, Torben; Andersen, Gitte; Weinsheimer, Shantel; Borch-Johnsen, Knut; Jørgensen, Torben; Shah, Svati H; Quyyumi, Arshed A; Granger, Christopher B; Reilly, Muredach P; Austin, Harland; Levey, Allan I; Vaccarino, Viola; Palsdottir, Ebba; Walters, G Bragi; Jonsdottir, Thorbjorg; Snorradottir, Steinunn; Magnusdottir, Dana; Gudmundsson, Gudmundur; Ferrell, Robert E; Sveinbjornsdottir, Sigurlaug; Hernesniemi, Juha; Niemelä, Mika; Limet, Raymond; Andersen, Karl; Sigurdsson, Gunnar; Benediktsson, Rafn; Verhoeven, Eric L G; Teijink, Joep A W; Grobbee, Diederick E; Rader, Daniel J; Collier, David A; Pedersen, Oluf; Pola, Roberto; Hillert, Jan; Lindblad, Bengt; Valdimarsson, Einar M; Magnadottir, Hulda B; Wijmenga, Cisca; Tromp, Gerard; Baas, Annette F; Ruigrok, Ynte M; van Rij, Andre M; Kuivaniemi, Helena; Powell, Janet T; Matthiasson, Stefan E; Gulcher, Jeffrey R; Thorgeirsson, Gudmundur; Kong, Augustine; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 40, No. 2, 2008, p. 217-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetikken ved ikkeautoimmun diabetes. Dansk Endokrinologisk Selskab. / Hansen, Torben; Pedersen, Oluf; Dansk Endokrinologisk Selskab.

    In: Ugeskrift for læger, Vol. 170, No. 12, 2008, p. 1021.

    Research output: Contribution to journalReviewResearch

  21. Published

    Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C. / Gutiérrez-Aguilar, Ruth; Froguel, Philippe; Hamid, Yasmin H; Benmezroua, Yamina; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, Torben; Pedersen, Oluf; Neve, Bernadette.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 8, 2008, p. 3128-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Many sequence variants affecting diversity of adult human height. / Gudbjartsson, Daniel F; Walters, G Bragi; Thorleifsson, Gudmar; Stefansson, Hreinn; Halldorsson, Bjarni V; Zusmanovich, Pasha; Sulem, Patrick; Thorlacius, Steinunn; Gylfason, Arnaldur; Steinberg, Stacy; Helgadottir, Anna; Ingason, Andres; Steinthorsdottir, Valgerdur; Olafsdottir, Elinborg J; Olafsdottir, Gudridur H; Jonsson, Thorvaldur; Borch-Johnsen, Knut; Hansen, Torben; Andersen, Gitte; Jørgensen, Torben; Pedersen, Oluf; Aben, Katja K; Witjes, J Alfred; Swinkels, Dorine W; den Heijer, Martin; Franke, Barbara; Verbeek, Andre L M; Becker, Diane M; Yanek, Lisa R; Becker, Lewis C; Tryggvadottir, Laufey; Rafnar, Thorunn; Gulcher, Jeffrey; Kiemeney, Lambertus A; Kong, Augustine; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 40, No. 5, 2008, p. 609-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Increased recovery rates of phosphocreatine (PCr) and inorganic phosphate (Pi) after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in carriers of the fat mass and obesity-associated FTO genotypes. / Grunnet, Louise Groth; Brøns, Charlotte; Jacobsen, Stine; Nielsen, Emma; Astrup, Arne; Hansen, Torben; Pedersen, Oluf; Poulsen, Pernille; Quistorff, Bjørn; Vaag, Allan.

    In: Diabetes, Vol. 57, No. Suppl. 1, 2008, p. A329.

    Research output: Contribution to journalConference abstract in journalResearch

  24. Published

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes. / Grarup, Niels; Andersen, Gitte; Krarup, Nikolaj Thure; Albrechtsen, Anders; Schmitz, Ole; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 57, No. 9, 2008, p. 2534-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects. / Grarup, Niels; Andreasen, Camilla H; Andersen, Mette K; Albrechtsen, Anders; Sandbaek, Annelli; Lauritzen, Torsten; Borch-Johnsen, Knut; Jørgensen, Torben; Schmitz, Ole; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 6, 2008, p. 2294-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

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