Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2015
  2. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. / Forslund, Kristoffer; Hildebrand, Falk; Nielsen, Trine; Falony, Gwen; Le Chatelier, Emmanuelle; Sunagawa, Shinichi; Prifti, Edi; Vieira-Silva, Sara; Gudmundsdottir, Valborg; Pedersen, Helle Krogh; Arumugam, Manimozhiyan; Kristiansen, Karsten; Yvonne Voigt, Anita; Vestergaard, Henrik; Hercog, Rajna; Igor Costea, Paul; Roat Kultima, Jens; Li, Junhua; Jørgensen, Torben; Levenez, Florence; Dore, Joël; Nielsen, Henrik Bjørn; Brunak, Søren; Raes, Jeroen; Hansen, Torben; Wang, Jun; Dusko Ehrlich, S.; Bork, Peer; Pedersen, Oluf Borbye.

    In: Nature, Vol. 528, No. 7581, 2015, p. 262-266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity : a population-based study. / Bonfils, Linéa; Ellervik, Christina; Friedrich, Nele; Linneberg, Allan; Sandholt, Camilla H.; Jørgensen, Marit E; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Allin, Kristine H.

    In: Diabetologia, Vol. 58, No. 3, 2015, p. 523-533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women. / Iepsen, Eva Pers Winning; Lundgren, Julie Rehné; Hartmann, Bolette; Pedersen, Oluf; Hansen, Torben; Jørgensen, Niklas R; Jensen, Jens-Erik Beck; Holst, Jens J; Madsbad, Sten; Torekov, Signe Sørensen.

    In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 8, 2015, p. 2909 –2917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genome-wide association studies of human adiposity: Zooming in on synapses. / Sandholt, Camilla H.; Grarup, Niels; Pedersen, Oluf; Hansen, Torben.

    In: Molecular and Cellular Endocrinology, Vol. 418, No. Part 2, 2015, p. 90-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Greenlandic Inuit show genetic signatures of diet and climate adaptation. / Fumagalli, Matteo; Moltke, Ida; Grarup, Niels; Racimo, Fernando; Bjerregaard, Peter; Jørgensen, Marit E.; Korneliussen, Thorfinn Sand; Gerbault, Pascale; Skotte, Line; Linneberg, Allan René; Christensen, Cramer; Brandslund, Ivan; Jørgensen, Torben; Huerta-Sánchez, Emilia; Schmidt, Erik Berg; Pedersen, Oluf Borbye; Hansen, Torben; Albrechtsen, Anders; Nielsen, Rasmus.

    In: Science (New York, N.Y.), Vol. 349, No. 6254, 2015, p. 1343-1347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    MECHANISMS IN ENDOCRINOLOGY : Gut microbiota in patients with type 2 diabetes mellitus. / Allin, Kristine H.; Nielsen, Trine; Pedersen, Oluf.

    In: European Journal of Endocrinology, Vol. 172, No. 4, 2015, p. R167-R177.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle. / Fonvig, Cilius Esmann; Chabanova, Elizaveta; Ohrt, Johanne Dam; Nielsen, Louise Aas; Pedersen, Oluf; Hansen, Torben; Thomsen, Henrik S; Holm, Jens-Christian.

    In: B M C Pediatrics, Vol. 15, 196, 2015, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. / Besenbacher, Søren; Liu, Siyang; Gonzalez-Izarzugaza, Jose Maria; Grove, Jakob; Belling, Kirstine G; Bork-Jensen, Jette; Huang, Shujia; Als, Thomas Damm; Li, Shengting; Yadav, Rachita; Rubio García, Arcadio; Lescai, Francesco; Demontis, Ditte; Rao, Junhua; Ye, Weijian; Mailund, Thomas; Møllegaard Friborg, Rune; Pedersen, Christian N. S.; Xu, Ruiqi; Sun, Jihua; Liu, Hao; Wang, Ou; Cheng, Xiaofang; Flores, David; Rydza, Emil Karol; Rapacki, Kristoffer; Sørensen, John Damm; Chmura, Piotr Jaroslaw; Westergaard, David; Dworzynski, Piotr; Sørensen, Thorkild I. A.; Lund, Ole; Hansen, Torben; Xu, Xun; Li, Ning; Bolund, Lars; Pedersen, Oluf; Eiberg, Hans; Krogh, Anders; Børglum, Anders D.; Brunak, Søren; Kristiansen, Karsten; Schierup, Mikkel H; Wang, Jun; Gupta, Ramneek; Villesen, Palle; Rasmussen, Simon.

    In: Nature Communications, Vol. 6, 5969, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Obesity Beige adipocytes-will they beat obesity?. / Sandholt, Camilla H.; Pedersen, Oluf.

    In: Nature Reviews Endocrinology, Vol. 11, No. 12, 2015, p. 694-696.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren : a prevalence study. / Mor, A; Antonsen, S; Kahlert, J; Holsteen, V; Jørgensen, S.; Holm-Pedersen, J; Sørensen, H T; Pedersen, Oluf Borbye; Ehrenstein, V.

    In: International journal of obesity (2005), Vol. 39, No. 10, 2015, p. 1450-1455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG : a novel genometabolic cross-link between CD300LG and common metabolic phenotypes. / Støy, Julie; Kampmann, Ulla; Mengel, Annette; Magnusson, Nils E; Jessen, Niels; Grarup, Niels; Rungby, Jørgen; Stødkilde-Jørgensen, Hans; Brandslund, Ivan; Christensen, Cramer; Hansen, Torben; Pedersen, Oluf; Møller, Niels.

    In: BMJ open diabetes research & care, Vol. 3, No. 1, e000095, 2015, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress : Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686. / Nolan, Christopher J; Ruderman, Neil B; Kahn, Steven E; Pedersen, Oluf; Prentki, Marc.

    In: Diabetes, Vol. 64, No. 10, 2015, p. e38-9.

    Research output: Contribution to journalComment/debateResearchpeer-review

  14. Published

    The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes. / Balslev-Harder, Marie; Appel, Emil Vincent Rosenbaum; Grarup, Niels; Gjesing, Anette Marianne Prior; Ahluwalia, Tarun Veer Singh; Jørgensen, Torben; Christensen, Cramer; Brandslund, Ivan; Linneberg, Allan; Sørensen, Thorkild I A; Pedersen, Oluf; Hansen, Torben.

    In: PLOS ONE, Vol. 10, No. 3, e0120890, 2015, p. 1-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The gut microbiome in cardio-metabolic health. / Hansen, Tue Haldor; Gøbel, Rikke J; Hansen, Torben; Pedersen, Oluf.

    In: Genome Medicine, Vol. 7, 33, 2015, p. 1-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. / Kato, Norihiro; Loh, Marie; Takeuchi, Fumihiko; Verweij, Niek; Wang, Xu; Zhang, Weihua; Kelly, Tanika N; Saleheen, Danish; Lehne, Benjamin; Mateo Leach, Irene; Drong, Alexander W; Abbott, James; Wahl, Simone; Tan, Sian-Tsung; Scott, William R; Campanella, Gianluca; Chadeau-Hyam, Marc; Afzal, Uzma; Ahluwalia, Tarun Veer Singh; Bonder, Marc Jan; Chen, Peng; Dehghan, Abbas; Edwards, Todd L; Esko, Tõnu; Go, Min Jin; Harris, Sarah E; Hartiala, Jaana; Kasela, Silva; Kasturiratne, Anuradhani; Khor, Chiea-Chuen; Kleber, Marcus E; Li, Huaixing; Mok, Zuan Yu; Nakatochi, Masahiro; Sapari, Nur Sabrina; Saxena, Richa; Stewart, Alexandre F R; Stolk, Lisette; Tabara, Yasuharu; Teh, Ai Ling; Wu, Ying; Wu, Jer-Yuarn; Grarup, Niels; Justesen, Johanne M; Sparsø, Thomas Hempel; Hansen, Torben; Jørgensen, Torben; Linneberg, Allan; Pedersen, Oluf; Sørensen, Thorkild I A; BIOS Consortium.

    In: Nature Genetics, Vol. 47, No. 11, 2015, p. 1282-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. / Iepsen, E W; Lundgren, J; Dirksen, C; Jensen, J-Eb; Pedersen, O; Hansen, T; Madsbad, S; Holst, J J; Torekov, S S.

    In: International journal of obesity (2005), Vol. 39, No. 5, 2015, p. 834-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Uncovering the genetic history of the present-day greenlandic population. / Moltke, Ida; Fumagalli, Matteo; Korneliussen, Thorfinn Sand; Crawford, Jacob E; Bjerregaard, Peter; Jørgensen, Marit E; Grarup, Niels; Gulløv, Hans Christian; Linneberg, Allan René; Pedersen, Oluf Borbye; Hansen, Torben; Nielsen, Rasmus; Albrechtsen, Anders.

    In: American Journal of Human Genetics, Vol. 96, No. 1, 2015, p. 54-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2014
  20. Published

    Genomet og diabetes. / Allin, Kristine Højgaard; Hansen, Torben; Pedersen, Oluf Borbye.

    In: Ugeskrift for Laeger, Vol. 176, No. 23, V06140337, 10.11.2014, p. 2176-2179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Tarmbakterier kan have betydning for overvægt i barnealderen. / Fonvig, Cilius Esmann; Pihl, Andreas Friis; Hansen, Torben; Pedersen, Oluf Borbye; Holm, Jens-Christian.

    In: Ugeskrift for Laeger, Vol. 176, V03140171, 18.08.2014, p. 2-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    FTO genetic variants, dietary intake and body mass index : insights from 177 330 individuals. / Qi, Qibin; Oskari Kilpeläinen, Tuomas; Downer, Mary K; Tanaka, Toshiko; Smith, Caren E; Sluijs, Ivonne; Sonestedt, Emily; Chu, Audrey Y; Renström, Frida; Lin, Xiaochen; Angquist, Lars H; Huang, Jinyan; Liu, Zhonghua; Li, Yanping; Asif Ali, Muhammad; Xu, Min; Ahluwalia, Tarun Veer Singh; Boer, Jolanda M A; Chen, Peng; Daimon, Makoto; Eriksson, Johan; Perola, Markus; Friedlander, Yechiel; Gao, Yu-Tang; Heppe, Denise H M; Holloway, John W; Houston, Denise K; Kanoni, Stavroula; Kim, Yu-Mi; Laaksonen, Maarit A; Jääskeläinen, Tiina; Lee, Nanette R; Lehtimäki, Terho; Lemaitre, Rozenn N; Lu, Wei; Luben, Robert N; Manichaikul, Ani; Männistö, Satu; Marques-Vidal, Pedro; Monda, Keri L; Ngwa, Julius S; Perusse, Louis; van Rooij, Frank J A; Xiang, Yong-Bing; Wen, Wanqing; Wojczynski, Mary K; Zhu, Jingwen; Borecki, Ingrid B; Bouchard, Claude; Cai, Qiuyin; Cooper, Cyrus; Dedoussis, George V; Deloukas, Panos; Ferrucci, Luigi; Forouhi, Nita G; Hansen, Torben; Christiansen, Lene; Hofman, Albert; Johansson, Ingegerd; Jørgensen, Torben; Karasawa, Shigeru; Khaw, Kay-Tee; Kim, Mi-Kyung; Kristiansson, Kati; Li, Huaixing; Lin, Xu; Liu, Yongmei; Lohman, Kurt K; Long, Jirong; Mikkilä, Vera; Mozaffarian, Dariush; North, Kari; Pedersen, Oluf; Raitakari, Olli; Rissanen, Harri; Tuomilehto, Jaakko; van der Schouw, Yvonne T; Uitterlinden, André G; Carola Zillikens, M; Franco, Oscar H; Shyong Tai, E; Ou Shu, Xiao; Siscovick, David S; Toft, Ulla; Monique Verschuren, W M; Vollenweider, Peter; Wareham, Nicholas J; Witteman, Jacqueline C M; Zheng, Wei; Ridker, Paul M; Kang, Jae H; Liang, Liming; Jensen, Majken K; Curhan, Gary C; Pasquale, Louis R; Hunter, David J; Mohlke, Karen L; Uusitupa, Matti; Adrienne Cupples, L; Rankinen, Tuomo; Orho-Melander, Marju; Wang, Tao; Chasman, Daniel I; Franks, Paul W; Sørensen, Thorkild I A; Hu, Frank B; Loos, Ruth J F; Nettleton, Jennifer A; Qi, Lu.

    In: Human Molecular Genetics, Vol. 23, No. 25, 07.08.2014, p. 6961-6972.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Genetic susceptibility to type 2 diabetes and obesity : from genome-wide association studies to rare variants and beyond. / Grarup, Niels; Sandholt, Camilla H; Hansen, Torben; Pedersen, Oluf.

    In: Diabetologia, Vol. 57, No. 8, 08.2014, p. 1528-41.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility. / Guigas, B; de Leeuw van Weenen, J E; van Leeuwen, N; Simonis-Bik, A M; van Haeften, T W; Nijpels, G; Houwing-Duistermaat, J J; Beekman, M; Deelen, J; Havekes, L M; Penninx, B W J H; Vogelzangs, N; van 't Riet, E; Dehghan, A; Hofman, A; Witteman, J C; Uitterlinden, A G; Grarup, Niels; Jørgensen, Torben; Witte, D R; Lauritzen, T; Hansen, Torben; Pedersen, O; Hottenga, J; Romijn, J A; Diamant, M; Kramer, M H H; Heine, R J; Willemsen, G; Dekker, J M; Eekhoff, E M; Pijl, H; de Geus, E J; Slagboom, P E; 't Hart, L M.

    In: Diabetic Medicine, Vol. 31, No. 8, 08.2014, p. 1001-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist : A Double-Blind, Randomized, Crossover Trial. / Ostoft, Signe H; Bagger, Jonatan I; Hansen, Torben; Pedersen, Oluf; Faber, Jens; Holst, Jens Juul; Knop, Filip K; Vilsbøll, Tina.

    In: Diabetes Care, Vol. 37, No. 7, 14.06.2014, p. 1797-1805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients. / Gjesing, Anette Marianne Prior; Hornbak, Malene; Allin, Kristine H.; Ekstrøm, Claus Thorn; Urhammer, Søren A.; Eiberg, Hans; Pedersen, Oluf; Hansen, Torben.

    In: Diabetologia, Vol. 57, No. 6, 06.2014, p. 1173-1181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Lessons from whole-exome sequencing in MODYX families. / Dusatkova, Petra; Fang, Mingyan; Pruhova, Stepanka; Gjesing, Anette P; Cinek, Ondrej; Hansen, Torben; Pedersen, Oluf B; Xu, Xun; Lebl, Jan.

    In: Diabetes Research and Clinical Practice, Vol. 104, No. 3, 06.2014, p. e72-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

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