Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population. / Lauenborg, Jeannet; Mathiesen, Elisabeth; Hansen, Torben; Glümer, Charlotte; Jørgensen, Torben; Borch-Johnsen, Knut; Hornnes, Peter; Pedersen, Oluf; Damm, Peter.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 90, No. 7, 2005, p. 4004-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. / Helgadottir, Anna; Thorleifsson, Gudmar; Magnusson, Kristinn P; Grétarsdottir, Solveig; Steinthorsdottir, Valgerdur; Manolescu, Andrei; Jones, Gregory T; Rinkel, Gabriel J E; Blankensteijn, Jan D; Ronkainen, Antti; Jääskeläinen, Juha E; Kyo, Yoshiki; Lenk, Guy M; Sakalihasan, Natzi; Kostulas, Konstantinos; Gottsäter, Anders; Flex, Andrea; Stefansson, Hreinn; Hansen, Torben; Andersen, Gitte; Weinsheimer, Shantel; Borch-Johnsen, Knut; Jørgensen, Torben; Shah, Svati H; Quyyumi, Arshed A; Granger, Christopher B; Reilly, Muredach P; Austin, Harland; Levey, Allan I; Vaccarino, Viola; Palsdottir, Ebba; Walters, G Bragi; Jonsdottir, Thorbjorg; Snorradottir, Steinunn; Magnusdottir, Dana; Gudmundsson, Gudmundur; Ferrell, Robert E; Sveinbjornsdottir, Sigurlaug; Hernesniemi, Juha; Niemelä, Mika; Limet, Raymond; Andersen, Karl; Sigurdsson, Gunnar; Benediktsson, Rafn; Verhoeven, Eric L G; Teijink, Joep A W; Grobbee, Diederick E; Rader, Daniel J; Collier, David A; Pedersen, Oluf; Pola, Roberto; Hillert, Jan; Lindblad, Bengt; Valdimarsson, Einar M; Magnadottir, Hulda B; Wijmenga, Cisca; Tromp, Gerard; Baas, Annette F; Ruigrok, Ynte M; van Rij, Andre M; Kuivaniemi, Helena; Powell, Janet T; Matthiasson, Stefan E; Gulcher, Jeffrey R; Thorgeirsson, Gudmundur; Kong, Augustine; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 40, No. 2, 2008, p. 217-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load. / Holmkvist, Johan; Banasik, Karina; Andersen, Gitte; Unoki, Hiroyuki; Jensen, Thomas Skot; Pisinger, Charlotta; Borch-Johnsen, Knut; Sandbaek, Annelli; Lauritzen, Torsten; Brunak, Sören; Maeda, Shiro; Hansen, Torben; Pedersen, Oluf.

    In: PLoS ONE, Vol. 4, No. 6, 2009, p. e5872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. / Kato, Norihiro; Loh, Marie; Takeuchi, Fumihiko; Verweij, Niek; Wang, Xu; Zhang, Weihua; Kelly, Tanika N; Saleheen, Danish; Lehne, Benjamin; Mateo Leach, Irene; Drong, Alexander W; Abbott, James; Wahl, Simone; Tan, Sian-Tsung; Scott, William R; Campanella, Gianluca; Chadeau-Hyam, Marc; Afzal, Uzma; Ahluwalia, Tarun Veer Singh; Bonder, Marc Jan; Chen, Peng; Dehghan, Abbas; Edwards, Todd L; Esko, Tõnu; Go, Min Jin; Harris, Sarah E; Hartiala, Jaana; Kasela, Silva; Kasturiratne, Anuradhani; Khor, Chiea-Chuen; Kleber, Marcus E; Li, Huaixing; Mok, Zuan Yu; Nakatochi, Masahiro; Sapari, Nur Sabrina; Saxena, Richa; Stewart, Alexandre F R; Stolk, Lisette; Tabara, Yasuharu; Teh, Ai Ling; Wu, Ying; Wu, Jer-Yuarn; Grarup, Niels; Justesen, Johanne M; Sparsø, Thomas Hempel; Hansen, Torben; Jørgensen, Torben; Linneberg, Allan; Pedersen, Oluf; Sørensen, Thorkild I A; BIOS Consortium.

    In: Nature Genetics, Vol. 47, No. 11, 2015, p. 1282-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. / Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P; Manning, Alisa K; Grarup, Niels; Sim, Xueling; Barnes, Daniel R; Witkowska, Kate; Staley, James R; Tragante, Vinicius; Tukiainen, Taru; Yaghootkar, Hanieh; Masca, Nicholas; Freitag, Daniel F; Ferreira, Teresa; Giannakopoulou, Olga; Tinker, Andrew; Harakalova, Magdalena; Mihailov, Evelin; Liu, Chunyu; Kraja, Aldi T; Nielsen, Sune Fallgaard; Rasheed, Asif; Samuel, Maria; Zhao, Wei; Bonnycastle, Lori L; Jackson, Anne U; Narisu, Narisu; Swift, Amy J; Southam, Lorraine; Marten, Jonathan; Huyghe, Jeroen R; Stančáková, Alena; Fava, Cristiano; Ohlsson, Therese; Matchan, Angela; Stirrups, Kathleen E; Bork-Jensen, Jette; Gjesing, Anette P; Kontto, Jukka; Perola, Markus; Shaw-Hawkins, Susan; Havulinna, Aki S; Husemoen, Lise L; Linneberg, Allan; Hansen, Torben; Pedersen, Oluf; Nordestgaard, Børge Grønne; CHARGE-Heart Failure Consortium.

    In: Nature Genetics, Vol. 48, No. 10, 12.09.2016, p. 1151-1161.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Transcriptional interactions suggest niche segregation among microorganisms in the human gut. / Plichta, Damian Rafal; Juncker, Agnieszka Sierakowska; Bertalan, Marcelo; Rettedal, Elizabeth; Gautier, Laurent; Varela, Encarna; Manichanh, Chaysavanh; Fouqueray, Charlène; Levenez, Florence; Nielsen, Trine; Doré, Joël; Machado, Ana Manuel Dantas; de Evgrafov, Mari Cristina Rodriguez; Hansen, Torben; Jørgensen, Torben; Bork, Peer; Guarner, Francisco; Pedersen, Oluf; Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium; Sommer, Morten O A; Ehrlich, S Dusko; Sicheritz-Pontén, Thomas; Brunak, Søren; Nielsen, H Bjørn.

    In: Nature Microbiology, Vol. 1, 16152, 26.08.2016, p. 1-6.

    Research output: Contribution to journalLetterResearchpeer-review

  7. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. / Iepsen, E W; Lundgren, J; Dirksen, C; Jensen, J-Eb; Pedersen, O; Hansen, T; Madsbad, S; Holst, J J; Torekov, S S.

    In: International journal of obesity (2005), Vol. 39, No. 5, 2015, p. 834-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. / Voight, Benjamin F; Scott, Laura J; Steinthorsdottir, Valgerdur; Morris, Andrew P; Dina, Christian; Welch, Ryan P; Zeggini, Eleftheria; Huth, Cornelia; Aulchenko, Yurii S; Thorleifsson, Gudmar; McCulloch, Laura J; Ferreira, Teresa; Grallert, Harald; Amin, Najaf; Wu, Guanming; Willer, Cristen J; Raychaudhuri, Soumya; McCarroll, Steve A; Langenberg, Claudia; Hofmann, Oliver M; Dupuis, Josée; Qi, Lu; Segrè, Ayellet V; van Hoek, Mandy; Navarro, Pau; Ardlie, Kristin; Balkau, Beverley; Benediktsson, Rafn; Bennett, Amanda J; Blagieva, Roza; Boerwinkle, Eric; Bonnycastle, Lori L; Bengtsson Boström, Kristina; Bravenboer, Bert; Bumpstead, Suzannah; Burtt, Noisël P; Charpentier, Guillaume; Chines, Peter S; Cornelis, Marilyn; Couper, David J; Crawford, Gabe; Doney, Alex S F; Elliott, Katherine S; Elliott, Amanda L; Erdos, Michael R; Grarup, Niels; Jørgensen, Torben; Sparsø, Thomas; Hansen, Torben; Pedersen, Oluf; MAGIC investigators.

    In: Nature Genetics, Vol. 42, No. 7, 01.07.2010, p. 579-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health. / Ibrügger, Sabine; Gøbel, Rikke Juul; Vestergaard, Henrik; Licht, Tine Rask; Frøkiær, Hanne; Linneberg, Allan René; Hansen, Torben; Gupta, Ramneek; Pedersen, Oluf Borbye; Kristensen, Mette Bredal; Lauritzen, Lotte.

    In: Journal of Clinical Trials, Vol. 4, No. 4, 1000178, 2014.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. / Gudmundsson, Julius; Sulem, Patrick; Steinthorsdottir, Valgerdur; Bergthorsson, Jon T; Thorleifsson, Gudmar; Manolescu, Andrei; Rafnar, Thorunn; Gudbjartsson, Daniel; Agnarsson, Bjarni A; Baker, Adam; Sigurdsson, Asgeir; Benediktsdottir, Kristrun R; Jakobsdottir, Margret; Blondal, Thorarinn; Stacey, Simon N; Helgason, Agnar; Gunnarsdottir, Steinunn; Olafsdottir, Adalheidur; Kristinsson, Kari T; Birgisdottir, Birgitta; Ghosh, Shyamali; Thorlacius, Steinunn; Magnusdottir, Dana; Stefansdottir, Gerdur; Kristjansson, Kristleifur; Bagger, Yu; Wilensky, Robert L; Reilly, Muredach P; Morris, Andrew D; Kimber, Charlotte H; Adeyemo, Adebowale; Chen, Yuanxiu; Zhou, Jie; So, Wing-Yee; Tong, Peter C Y; Ng, Maggie C Y; Hansen, Torben; Andersen, Gitte; Borch-Johnsen, Knut; Jorgensen, Torben; Tres, Alejandro; Fuertes, Fernando; Ruiz-Echarri, Manuel; Asin, Laura; Saez, Berta; van Boven, Erica; Klaver, Siem; Swinkels, Dorine W; Aben, Katja K; Graif, Theresa; Cashy, John; Suarez, Brian K; van Vierssen Trip, Onco; Frigge, Michael L; Ober, Carole; Hofker, Marten H; Wijmenga, Cisca; Christiansen, Claus; Rader, Daniel J; Palmer, Colin N A; Rotimi, Charles; Chan, Juliana C N; Pedersen, Oluf; Sigurdsson, Gunnar; Benediktsson, Rafn; Jonsson, Eirikur; Einarsson, Gudmundur V; Mayordomo, Jose I; Catalona, William J; Kiemeney, Lambertus A; Barkardottir, Rosa B; Gulcher, Jeffrey R; Thorsteinsdottir, Unnur; Kong, Augustine; Stefansson, Kari.

    In: Nature Genetics, Vol. 39, No. 8, 2007, p. 977-983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Type 2 Diabetes Risk Alleles Near BCAR1 and in ANK1 Associate With Decreased ß-Cell Function Whereas Risk Alleles Near ANKRD55 and GRB14 Associate With Decreased Insulin Sensitivity in the Danish Inter99 Cohort. / Harder, Marie N; Ribel-Madsen, Rasmus; Justesen, Johanne M; Sparsø, Thomas; Galijatovic, Ehm Astrid Andersson; Grarup, Niels; Jørgensen, Torben; Linneberg, Allan; Hansen, Torben; Pedersen, Oluf.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 98, No. 4, 01.04.2013, p. 801-806.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release. / Nielsen, Trine; Sparsø, T; Grarup, N; Jørgensen, Torben; Pisinger, Charlotta Holm; Witte, Daniel Rinse; Hansen, T; Pedersen, Oluf; Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium.

    In: Diabetologica, Vol. 54, No. 5, 01.05.2011, p. 1052-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight. / Andersson, E A; Pilgaard, K; Pisinger, C; Harder, M N; Grarup, N; Faerch, K; Poulsen, P; Witte, D R; Jørgensen, Torben; Vaag, A; Hansen, T; Pedersen, Oluf.

    In: Diabetologia, Vol. 53, No. 9, 01.09.2010, p. 1908-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control. / Vestergaard, H; Lund, S; Bjørbaek, C; Pedersen, O.

    In: Diabetologia, Vol. 38, No. 10, 10.1995, p. 1230-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Uncovering the genetic history of the present-day greenlandic population. / Moltke, Ida; Fumagalli, Matteo; Korneliussen, Thorfinn Sand; Crawford, Jacob E; Bjerregaard, Peter; Jørgensen, Marit E; Grarup, Niels; Gulløv, Hans Christian; Linneberg, Allan René; Pedersen, Oluf Borbye; Hansen, Torben; Nielsen, Rasmus; Albrechtsen, Anders.

    In: American Journal of Human Genetics, Vol. 96, No. 1, 2015, p. 54-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts. / Friedrich, Nele; Pietzner, Maik; Cannet, Claire; Thuesen, Betina H; Hansen, Torben; Wallaschofski, Henri; Grarup, Niels; Skaaby, Tea; Budde, Kathrin; Pedersen, Oluf; Nauck, Matthias; Linneberg, Allan.

    In: PLOS ONE, Vol. 12, No. 3, e0173078, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes. / Kjaer, Laura Kofoed; Cejvanovic, Vanja; Henriksen, Trine; Hansen, Torben; Pedersen, Oluf; Christensen, Cramer Kjeldahl; Torp-Pedersen, Christian; Gerds, Thomas Alexander; Brandslund, Ivan; Mandrup-Poulsen, Thomas; Poulsen, Henrik Enghusen.

    In: Free Radical Research, Vol. 53, No. 6, 03.06.2019, p. 694-703.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes. / Winther, Signe A.; Øllgaard, Jens C.; Tofte, Nete; Tarnow, Lise; Wang, Zeneng; Ahluwalia, Tarunveer S.; Jorsal, Anders; Theilade, Simone; Parving, Hans-Henrik; Hansen, Tine W.; Hazen, Stanley L.; Pedersen, Oluf; Rossing, Peter.

    In: Diabetes Care, Vol. 42, No. 8, 2019, p. 1512-1520.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus : Combined results of the Inter99 and Botnia studies. / Lyssenko, Valeriya; Jørgensen, Torben; Gerwien, Robert W; Hansen, Torben; Rowe, Michael W; McKenna, Michael P; Kolberg, Janice; Pedersen, Oluf; Borch-Johnsen, Knut; Groop, Leif.

    In: Diabetes and Vascular Disease Research, Vol. 9, No. 1, 01.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99). / Urdea, Mickey; Kolberg, Janice; Wilber, Judith; Gerwien, Robert; Moler, Edward; Rowe, Michael; Jorgensen, Paul; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben; Borch-Johnsen, Knut.

    In: Journal of Diabetes Science and Technology, Vol. 3, No. 4, 2009, p. 748-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies. / Friedrich, Björn; Weyrich, Peter; Stancáková, Alena; Wang, Jianjung; Kuusisto, Johanna; Laakso, Markku; Sesti, Giorgio; Succurro, Elena; Smith, Ulf; Hansen, Torben; Pedersen, Oluf; Machicao, Fausto; Schäfer, Silke; Lang, Florian; Risler, Teut; Ullrich, Susanne; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich.

    In: PLoS ONE, Vol. 3, No. 11, 2008, p. e3506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. / Nioi, Paul; Sigurdsson, Asgeir; Thorleifsson, Gudmar; Helgason, Hannes; Agustsdottir, Arna B; Norddahl, Gudmundur L; Helgadottir, Anna; Magnusdottir, Audur; Jonasdottir, Aslaug; Gretarsdottir, Solveig; Jonsdottir, Ingileif; Steinthorsdottir, Valgerdur; Rafnar, Thorunn; Swinkels, Dorine W; Galesloot, Tessel E; Grarup, Niels; Jørgensen, Torben; Vestergaard, Henrik; Hansen, Torben; Lauritzen, Torsten; Linneberg, Allan; Friedrich, Nele; Krarup, Nikolaj T; Fenger, Mogens; Abildgaard, Ulrik; Hansen, Peter R; Galløe, Anders M; Braund, Peter S; Nelson, Christopher P; Hall, Alistair S; Williams, Michael J A; van Rij, Andre M; Jones, Gregory T; Patel, Riyaz S; Levey, Allan I; Hayek, Salim; Shah, Svati H; Reilly, Muredach; Eyjolfsson, Gudmundur I; Sigurdardottir, Olof; Olafsson, Isleifur; Kiemeney, Lambertus A; Quyyumi, Arshed A; Rader, Daniel J; Kraus, William E; Samani, Nilesh J; Pedersen, Oluf; Thorgeirsson, Gudmundur; Masson, Gisli; Holm, Hilma; Gudbjartsson, Daniel; Sulem, Patrick; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: New England Journal of Medicine, Vol. 374, No. 22, 02.06.2016, p. 2131-2141.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study. / Boesgaard, Trine Welløv; Gjesing, Anette Prior; Grarup, Niels; Rutanen, Jarno; Jansson, Per-Anders; Hribal, Marta Letizia; Sesti, Giorgio; Fritsche, Andreas; Stefan, Norbert; Staiger, Harald; Häring, Hans; Smith, Ulf; Laakso, Markku; Pedersen, Oluf; Hansen, Torben; EUGENE2 Consortium.

    In: PLoS ONE, Vol. 4, No. 9, 2009, p. e7236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. / Boesgaard, T W; Grarup, N; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, T; Pedersen, Oluf; Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC).

    In: Diabetologia, Vol. 53, No. 8, 01.08.2010, p. 1647-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects. / Torekov, Signe Sørensen; Larsen, L H; Andersen, G; Albrechtsen, A; Glümer, C; Borch-Johnsen, K; Jørgensen, T; Hansen, T; Pedersen, O.

    In: Diabetologia, Vol. 49, No. 11, 2006, p. 2653-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 919113