Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. 2012
  2. Published

    TFAP2B influences the effect of dietary fat on weight loss under energy restriction. / Stocks, Tanja; Angquist, Lars; Banasik, Karina; Harder, Marie Neergaard; Taylor, Moira A; Hager, Jörg; Arner, Peter; Oppert, Jean-Michel; Martinez, J Alfredo; Polak, Jan; Rousseau, Francis; Langin, Dominique; Rössner, Stephan; Holst, Claus; Macdonald, Ian A; Kamatani, Yoichiro; Pfeiffer, Andreas F H; Kunesova, Marie; Saris, Wim H M; Hansen, Torben; Pedersen, Oluf; Astrup, Arne; Sørensen, Thorkild I.A.

    In: P L o S One, Vol. 7, No. 8, 2012, p. e43212.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation. / Krarup, Nikolaj Thure; Grarup, Niels; Banasik, Karina; Friedrichsen, Martin; Færch, Kristine; Sandholt, Camilla Helene; Jørgensen, Torben; Poulsen, Pernille; Witte, Daniel Rinse; Vaag, Allan; Sørensen, Thorkild I.A.; Pedersen, Oluf; Hansen, Torben.

    In: P L o S One, Vol. 7, No. 7, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals. / Banasik, Karina; Hollensted, Mette; Andersson, Ehm; Sparsø, Thomas; Sandbaek, Annelli; Lauritzen, Torsten; Jørgensen, Torben; Witte, Daniel R; Pedersen, Oluf; Hansen, Torben.

    In: B M C Medical Genetics, Vol. 13, 2012, p. 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity : a study of obesity and related metabolic traits among 17¿636 Danes. / Andersen, G; Dalgaard, L T; Justesen, J M; Anthonsen, S; Nielsen, T; Thørner, L W; Witte, D; Jørgensen, T; Clausen, J O; Lauritzen, Torsten; Holmkvist, J; Hansen, T; Pedersen, O.

    In: International Journal of Obesity, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2011
  7. Published

    The influence of parental history of diabetes and offspring birthweight on offspring glucose metabolism in adulthood. / Lauenborg, Jeannet; Jørgensen, Mie Kw; Damm, Peter; Major-Pedersen, Atheline; Eiberg, Hans; Urhammer, Søren; Pedersen, Oluf; Hansen, Torben.

    In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 90, No. 12, 12.2011, p. 1357-1363.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk : A Meta-Analysis of 218,166 Adults and 19,268 Children. / Oskari Kilpeläinen, Tuomas; Qi, Lu; Brage, Soren; Sharp, Stephen J; Sonestedt, Emily; Demerath, Ellen; Ahmad, Tariq; Mora, Samia; Kaakinen, Marika; Sandholt, Camilla Helene; Holzapfel, Christina; Autenrieth, Christine S; Hyppönen, Elina; Cauchi, Stéphane; He, Meian; Kutalik, Zoltan; Kumari, Meena; Stancáková, Alena; Meidtner, Karina; Balkau, Beverley; Tan, Jonathan T; Mangino, Massimo; Timpson, Nicholas J; Song, Yiqing; Zillikens, M Carola; Jablonski, Kathleen A; Garcia, Melissa E; Johansson, Stefan; Bragg-Gresham, Jennifer L; Wu, Ying; van Vliet-Ostaptchouk, Jana V; Onland-Moret, N Charlotte; Zimmermann, Esther; Rivera, Natalia V; Tanaka, Toshiko; Stringham, Heather M; Silbernagel, Günther; Kanoni, Stavroula; Feitosa, Mary F; Snitker, Soren; Ruiz, Jonatan R; Metter, Jeffery; Larrad, Maria Teresa Martinez; Atalay, Mustafa; Hakanen, Maarit; Amin, Najaf; Cavalcanti-Proença, Christine; Grøntved, Anders; Hallmans, Göran; Jansson, John-Olov; Kuusisto, Johanna; Kähönen, Mika; Lutsey, Pamela L; Nolan, John J; Palla, Luigi; Pedersen, Oluf; Pérusse, Louis; Renström, Frida; Scott, Robert A; Shungin, Dmitry; Sovio, Ulla; Tammelin, Tuija H; Rönnemaa, Tapani; Lakka, Timo A; Uusitupa, Matti; Rios, Manuel Serrano; Ferrucci, Luigi; Bouchard, Claude; Meirhaeghe, Aline; Fu, Mao; Walker, Mark; Borecki, Ingrid B; Dedoussis, George V; Fritsche, Andreas; Ohlsson, Claes; Boehnke, Michael; Bandinelli, Stefania; van Duijn, Cornelia M; Ebrahim, Shah; Lawlor, Debbie A; Gudnason, Vilmundur; Harris, Tamara B; Sørensen, Thorkild I A; Mohlke, Karen L; Hofman, Albert; Uitterlinden, André G; Tuomilehto, Jaakko; Lehtimäki, Terho; Raitakari, Olli; Isomaa, Bo; Njølstad, Pål R; Florez, Jose C; Liu, Simin; Ness, Andy; Spector, Timothy D; Tai, E Shyong; Froguel, Philippe; Boeing, Heiner; Laakso, Markku; Marmot, Michael; Bergmann, Sven; Power, Chris; Khaw, Kay-Tee; Chasman, Daniel; Ridker, Paul; Hansen, Torben; Monda, Keri L; Illig, Thomas; Järvelin, Marjo-Riitta; Wareham, Nicholas J; Hu, Frank B; Groop, Leif C; Orho-Melander, Marju; Ekelund, Ulf; Franks, Paul W; Loos, Ruth J F.

    In: P L o S Medicine (Online), Vol. 8, No. 11, 01.11.2011, p. e1001116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge. / Andersson, Ehm A; Harder, Marie N; Pilgaard, Kasper; Pisinger, Charlotta; Stancáková, Alena; Kuusisto, Johanna; Grarup, Niels; Færch, Kristine; Poulsen, Pernille; Witte, Daniel R; Jørgensen, Torben; Vaag, Allan; Laakso, Markku; Pedersen, Oluf; Hansen, Torben.

    In: P L o S One, Vol. 6, No. 11, 11.2011, p. e27096.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals. / Burgdorf, K S; Gjesing, A P; Grarup, N; Justesen, J M; Sandholt, C H; Witte, D R; Jørgensen, T; Madsbad, S; Hansen, T; Pedersen, O.

    In: Diabetologia, Vol. 55, No. 1, 28.09.2011, p. 105-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Comparison of Accuracy of Diabetes Risk Score and Components of the Metabolic Syndrome in Assessing Risk of Incident Type 2 Diabetes in Inter99 Cohort. / Shafizadeh, Tracy B; Moler, Edward J; Kolberg, Janice A; Nguyen, Uyen Thao; Hansen, Torben; Jørgensen, Torben; Pedersen, Oluf; Borch-Johnsen, Knut.

    In: P L o S One, Vol. 6, No. 7, 01.07.2011, p. e22863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes. / Bille, Dorthe S; Banasik, Karina; Justesen, Johanne M; Sandholt, Camilla H; Sandbæk, Annelli; Lauritzen, Torsten; Jørgensen, Torben; Witte, Daniel R; Holm, Jens-Christian; Hansen, Torben; Pedersen, Oluf.

    In: P L o S One, Vol. 6, No. 6, 01.06.2011, p. e20640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Familial mild hyperglycemia associated with a novel ABCC8-V84I mutation within three generations. / Gonsorcikova, Lucie; Vaxillaire, Martine; Pruhova, Stepanka; Dechaume, Aurélie; Dusatkova, Petra; Cinek, Ondrej; Pedersen, Oluf; Froguel, Philippe; Hansen, Torben; Lebl, Jan.

    In: Pediatric Diabetes, Vol. 12, No. 3pt2, 01.05.2011, p. 266-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release. / Nielsen, Trine; Sparsø, T; Grarup, N; Jørgensen, Torben; Pisinger, Charlotta Holm; Witte, Daniel Rinse; Hansen, T; Pedersen, Oluf; Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium.

    In: Diabetologica, Vol. 54, No. 5, 01.05.2011, p. 1052-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load. / Hornbak, Malene; Banasik, Karina; Justesen, Johanne Marie; Krarup, Nikolaj Thure; Sandholt, Camilla Helene; Andersson, Åsa; Sandbaek, Annelli; Lauritzen, Torsten; Pisinger, Charlotta; Witte, Daniel R; Sørensen, Thorkild I.A.; Pedersen, Oluf; Hansen, Torben.

    In: BMC Medical Genetics, Vol. 12, No. 1, 06.01.2011, p. 4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. / Stacey, Simon N; Sulem, Patrick; Jonasdottir, Aslaug; Masson, Gisli; Gudmundsson, Julius; Gudbjartsson, Daniel F; Magnusson, Olafur T; Gudjonsson, Sigurjon A; Sigurgeirsson, Bardur; Thorisdottir, Kristin; Ragnarsson, Rafn; Benediktsdottir, Kristrun R; Nexø, Bjørn Andersen; Tjønneland, Anne; Overvad, Kim; Rudnai, Peter; Gurzau, Eugene; Koppova, Kvetoslava; Hemminki, Kari; Corredera, Cristina; Fuentelsaz, Victoria; Grasa, Pilar; Navarrete, Sebastian; Fuertes, Fernando; García-Prats, Maria D; Sanambrosio, Enrique; Panadero, Angeles; De Juan, Ana; Garcia, Almudena; Rivera, Fernando; Planelles, Dolores; Soriano, Virtudes; Requena, Celia; Aben, Katja K; van Rossum, Michelle M; Cremers, Ruben G H M; van Oort, Inge M; van Spronsen, Dick-Johan; Schalken, Jack A; Peters, Wilbert H M; Helfand, Brian T; Donovan, Jenny L; Hamdy, Freddie C; Badescu, Daniel; Codreanu, Ovidiu; Banasik, Karina; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; Swedish Low-risk Colorectal Cancer Study Group.

    In: Nature Genetics, Vol. 43, No. 11, 01.01.2011, p. 1098-1103.

    Research output: Contribution to journalLetterResearchpeer-review

  17. Published

    A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study. / Thyssen, Jacob P; Linneberg, Allan; Carlsen, Berit C; Johansen, Jeanne D; Engkilde, Kåre; Hansen, Torben; Pociot, Flemming; Pedersen, Oluf; Meldgaard, Michael; Szecsi, Pal B; Stender, Steen; Menné, Torkil.

    In: BMJ Open, Vol. 1, No. 1, 01.01.2011, p. e000062.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. / Banasik, Karina; Justesen, Johanne M; Hornbak, Malene; Krarup, Nikolaj T; Gjesing, Anette P; Sandholt, Camilla Helene; Søndergaard Jensen, Thomas; Grarup, Niels; Andersson, Åsa; Jørgensen, Torben; Witte, Daniel R; Sandbæk, Annelli; Lauritzen, Torsten; Thorens, Bernard; Brunak, Søren; Sørensen, Thorkild I A; Pedersen, Oluf; Hansen, Torben.

    In: P L o S One, Vol. 6, No. 1, 01.01.2011, p. e16542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    Corrigendum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. / Heid, Iris M; Jackson, Anne U; Randall, Joshua C; Winkler, Thomas W; Qi, Lu; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Zillikens, M Carola; Speliotes, Elizabeth K; Mägi, Reedik; Workalemahu, Tsegaselassie; White, Charles C; Bouatia-Naji, Nabila; Harris, Tamara B; Berndt, Sonja I; Ingelsson, Erik; Willer, Cristen J; Weedon, Michael N; Luan, Jian'an; Vedantam, Sailaja; Esko, Tõnu; Kilpeläinen, Tuomas O; Kutalik, Zoltán; Li, Shengxu; Monda, Keri L; Dixon, Anna L; Holmes, Christopher C; Kaplan, Lee M; Liang, Liming; Min, Josine L; Moffatt, Miriam F; Molony, Cliona; Nicholson, George; Schadt, Eric E; Zondervan, Krina T; Feitosa, Mary F; Ferreira, Teresa; Allen, Hana Lango; Weyant, Robert J; Wheeler, Eleanor; Wood, Andrew R; Estrada, Karol; Goddard, Michael E; Lettre, Guillaume; Mangino, Massimo; Nyholt, Dale R; Purcell, Shaun; Vernon Smith, Albert; Visscher, Peter M; Yang, Jian; McCarroll, Steven A; Nemesh, James; Voight, Benjamin F; Absher, Devin; Amin, Najaf; Aspelund, Thor; Coin, Lachlan; Glazer, Nicole L; Hayward, Caroline; Heard-Costa, Nancy L; Hottenga, Jouke-Jan; Johansson, Asa; Johnson, Toby; Kaakinen, Marika; Kapur, Karen; Ketkar, Shamika; Knowles, Joshua W; Kraft, Peter; Kraja, Aldi T; Lamina, Claudia; Leitzmann, Michael F; McKnight, Barbara; Morris, Andrew P; Ong, Ken K; Perry, John R B; Peters, Marjolein J; Polasek, Ozren; Prokopenko, Inga; Rayner, Nigel W; Ripatti, Samuli; Rivadeneira, Fernando; Robertson, Neil R; Sanna, Serena; Sovio, Ulla; Surakka, Ida; Teumer, Alexander; van Wingerden, Sophie; Vitart, Veronique; Zhao, Jing Hua; Cavalcanti-Proença, Christine; Chines, Peter S; Fisher, Eva; Kulzer, Jennifer R; Lecoeur, Cecile; Narisu, Narisu; Sandholt, Camilla; Scott, Laura J; Silander, Kaisa; Stark, Klaus; Tammesoo, Mari-Liis; Teslovich, Tanya M; Timpson, Nicholas John; Watanabe, Richard M; Welch, Ryan; Chasman, Daniel I; Cooper, Matthew N; Jansson, John-Olov; Kettunen, Johannes; Lawrence, Robert W; Pellikka, Niina; Perola, Markus; Vandenput, Liesbeth; Alavere, Helene; Almgren, Peter; Atwood, Larry D; Bennett, Amanda J; Biffar, Reiner; Bonnycastle, Lori L; Bornstein, Stefan R; Buchanan, Thomas A; Campbell, Harry; Day, Ian N M; Dei, Mariano; Dörr, Marcus; Elliott, Paul; Erdos, Michael R; Eriksson, Johan G; Freimer, Nelson B; Fu, Mao; Gaget, Stefan; Geus, Eco J C; Gjesing, Anette P; Grallert, Harald; Gräßler, Jürgen; Groves, Christopher J; Guiducci, Candace; Hartikainen, Anna-Liisa; Hassanali, Neelam; Havulinna, Aki S; Herzig, Karl-Heinz; Hicks, Andrew A; Hui, Jennie; Igl, Wilmar; Jousilahti, Pekka; Jula, Antti; Kajantie, Eero; Kinnunen, Leena; Kolcic, Ivana; Koskinen, Seppo; Kovacs, Peter; Kroemer, Heyo K; Krzelj, Vjekoslav; Kuusisto, Johanna; Kvaloy, Kirsti; Laitinen, Jaana; Lantieri, Olivier; Lathrop, G Mark; Lokki, Marja-Liisa; Luben, Robert N; Ludwig, Barbara; McArdle, Wendy L; McCarthy, Anne; Morken, Mario A; Nelis, Mari; Neville, Matt J; Paré, Guillaume; Parker, Alex N; Peden, John F; Pichler, Irene; Pietiläinen, Kirsi H; Platou, Carl G P; Pouta, Anneli; Ridderstråle, Martin; Samani, Nilesh J; Saramies, Jouko; Sinisalo, Juha; Smit, Jan H; Strawbridge, Rona J; Stringham, Heather M; Swift, Amy J; Teder-Laving, Maris; Thomson, Brian; Usala, Gianluca; van Meurs, Joyce B J; van Ommen, Gert-Jan; Vatin, Vincent; Volpato, Claudia B; Wallaschofski, Henri; Walters, G Bragi; Widen, Elisabeth; Wild, Sarah H; Willemsen, Gonneke; Witte, Daniel R; Zgaga, Lina; Zitting, Paavo; Beilby, John P; James, Alan L; Kähönen, Mika; Lehtimäki, Terho; Nieminen, Markku S; Ohlsson, Claes; Palmer, Lyle J; Raitakari, Olli; Ridker, Paul M; Stumvoll, Michael; Tönjes, Anke; Viikari, Jorma; Balkau, Beverley; Ben-Shlomo, Yoav; Bergman, Richard N; Boeing, Heiner; Smith, George Davey; Ebrahim, Shah; Froguel, Philippe; Hansen, Torben; Hengstenberg, Christian; Hveem, Kristian; Isomaa, Bo; Jørgensen, Torben; Karpe, Fredrik; Khaw, Kay-Tee; Laakso, Markku; Lawlor, Debbie A; Marre, Michel; Meitinger, Thomas; Metspalu, Andres; Midthjell, Kristian; Pedersen, Oluf; Salomaa, Veikko; Schwarz, Peter E H; Tuomi, Tiinamaija; Tuomilehto, Jaakko; Valle, Timo T; Wareham, Nicholas J; Arnold, Alice M; Beckmann, Jacques S; Bergmann, Sven; Boerwinkle, Eric; Boomsma, Dorret I; Caulfield, Mark J; Collins, Francis S; Eiriksdottir, Gudny; Gudnason, Vilmundur; Gyllensten, Ulf; Hamsten, Anders; Hattersley, Andrew T; Hofman, Albert; Hu, Frank B; Illig, Thomas; Iribarren, Carlos; Jarvelin, Marjo-Riitta; Kao, W H Linda; Kaprio, Jaakko; Launer, Lenore J; Munroe, Patricia B; Oostra, Ben; Penninx, Brenda W; Pramstaller, Peter P; Psaty, Bruce M; Quertermous, Thomas; Rissanen, Aila; Rudan, Igor; Shuldiner, Alan R; Soranzo, Nicole; Spector, Timothy D; Syvanen, Ann-Christine; Uda, Manuela; Uitterlinden, André; Völzke, Henry; Vollenweider, Peter; Wilson, James F; Witteman, Jacqueline C; Wright, Alan F; Abecasis, Gonçalo R; Boehnke, Michael; Borecki, Ingrid B; Deloukas, Panos; Frayling, Timothy M; Groop, Leif C; Haritunians, Talin; Hunter, David J; Kaplan, Robert C; North, Kari E; O'Connell, Jeffrey R; Peltonen, Leena; Schlessinger, David; Strachan, David P; Hirschhorn, Joel N; Assimes, Themistocles L; Wichmann, H-Erich; Thorsteinsdottir, Unnur; van Duijn, Cornelia M; Stefansson, Kari; Cupples, L Adrienne; Loos, Ruth J F; Barroso, Inês; McCarthy, Mark I; Fox, Caroline S; Mohlke, Karen L; Lindgren, Cecilia M.

    In: Nature Genetics, Vol. 43, No. 11, 01.01.2011, p. 1164.

    Research output: Contribution to journalComment/debateResearchpeer-review

  21. Published

    Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes. / Gjesing, Anette P; Nielsen, Aneta A; Brandslund, Ivan; Christensen, Cramer; Sandbæk, Anneli; Jørgensen, Torben; Witte, Daniel; Bonnefond, Amélie; Froguel, Phillippe; Hansen, Torben; Pedersen, Oluf.

    In: B M C Medical Genetics, Vol. 12, 01.01.2011, p. 99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Studies of metabolic phenotypic correlates of 15 obesity associated gene variants. / Sandholt, Camilla Helene; Vestmar, Marie Aare; Bille, Dorthe Sadowa; Borglykke, Anders; Almind, Katrine; Hansen, Lars; Sandbæk, Annelli; Lauritzen, Torsten; Witte, Daniel; Jørgensen, Torben; Pedersen, Oluf; Hansen, Torben.

    In: P L o S One, Vol. 6, No. 9, 01.01.2011, p. e23531.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status. / Gjesing, Anette P; Vestmar, Marie A; Jørgensen, Torben; Heni, Martin; Holst, Jens J; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf.

    In: P L o S One, Vol. 6, No. 9, 01.01.2011, p. e23907.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins. / Banasik, Karina; Ribel-Madsen, Rasmus; Gjesing, Anette P; Wegner, Lise; Andersson, Åsa; Poulsen, Pernille; Borglykke, Anders; Witte, Daniel R; Pedersen, Oluf; Hansen, Torben; Vaag, Allan.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 1, 01.01.2011, p. E119-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A role for coding functional variants in HNF4A in type 2 diabetes susceptibility. / Jafar-Mohammadi, B; Groves, C J; Gjesing, A P; Herrera, B M; Winckler, W; Stringham, H M; Morris, A P; Lauritzen, Torsten; Doney, A S F; Morris, A D; Weedon, M N; Swift, A J; Kuusisto, J; Laakso, M; Altshuler, D; Hattersley, A T; Collins, F S; Boehnke, M; Hansen, T; Pedersen, O; Palmer, C N A; Frayling, T M; Gloyn, A L; McCarthy, M I; DIAGRAM Consortium.

    In: Diabetologia, Vol. 54, No. 1, 01.2011, p. 111-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity : a randomised trial of hypo-energetic high- versus low-fat diets. / L. Santos, José; De la Cruz, Rolando; Holst, Claus; Grau, Katrine; Naranjo, Carolina; Maiz, Alberto; Astrup, Arne; Saris, Wim H.M.; MacDonald, Ian; Oppert, Jean-Michel; Hansen, Torben; Pedersen, Oluf; Sørensen, Thorkild I.A.; Martinez, J. Alfredo; NUGENOB Consortium.

    In: P L o S One, Vol. 6, No. 6, 2011, p. e199934.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Associations between APOE variants and metabolic traits and the impact of psychological stress. / Kring, Sofia Inez Iqbal; Barefoot, John; Brummett, Berverly H.; Boyle, Stephen H.; Siegler, Ilene C.; Toubro, Søren; Hansen, Torben; Astrup, Arne; Pedersen, Oluf; Williams, Redford B.; Sørensen, Thorkild I.A.

    In: PLoS ONE, Vol. 6, No. 1, 2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Enterotypes of the human gut microbiome : [Plus]Corrigendum [Plus]Addendum. / Arumugam, Manimozhiyan; Raes, Jeroen; Pelletier, Eric; Le Paslier, Denis; Yamada, Takuji; Mende, Daniel R; Fernandes, Gabriel R; Tap, Julien; Bruls, Thomas; Batto, Jean-Michel; dos Santos, Marcelo Bertalan Quintanilha; Borruel, Natalia; Casellas, Francesc; Fernandez, Leyden; Gautier, Laurent; Hansen, Torben; Hattori, Masahira; Hayashi, Tetsuya; Kleerebezem, Michiel; Kurokawa, Ken; Leclerc, Marion; Levenez, Florence; Manichanh, Chaysavanh; Nielsen, H Bjørn; Nielsen, Trine; Pons, Nicolas; Poulain, Julie; Qin, Junjie; Sicheritz-Ponten, Thomas; Tims, Sebastian; Torrents, David; Ugarte, Edgardo; Zoetendal, Erwin G; Wang, Jun; Guarner, Francisco; Pedersen, Oluf; de Vos, Willem M; Brunak, Søren; Doré, Joel; Antolín, María; Artiguenave, François; Blottiere, Hervé M; Almeida, Mathieu; Brechot, Christian; Cara, Carlos; Chervaux, Christian; Cultrone, Antonella; Delorme, Christine; Denariaz, Gérard; Kristiansen, Karsten; MetaHIT Consortium.

    In: Nature, Vol. 473, No. 7346, 2011, p. 174-180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Estimation of allele frequency and association mapping using next-generation sequencing data. / Kim, Su Yeon; Lohmueller, Kirk E; Albrechtsen, Anders; Li, Yingrui; Korneliussen, Thorfinn Sand; Tian, Geng; Grarup, Niels; Jiang, Tao; Andersen, Gitte; Witte, Daniel; Jorgensen, Torben; Hansen, Torben; Pedersen, Oluf; Wang, Jun; Nielsen, Rasmus.

    In: B M C Bioinformatics, Vol. 12, 2011, p. 231.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Genome wide association study identifies KCNMA1 contributing to human obesity. / Jiao, Hong; Arner, Peter; Hoffstedt, Johan; Brodin, David; Dubern, Beatrice; Czernichow, Sébastien; van't Hooft, Ferdinand; Axelsson, Tomas; Pedersen, Oluf; Hansen, Torben; Sørensen, Thorkild I A; Hebebrand, Johannes; Kere, Juha; Dahlman-Wright, Karin; Hamsten, Anders; Clement, Karine; Dahlman, Ingrid.

    In: B M C Medical Genomics, Vol. 4, 2011, p. 51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Genome-wide population-based association study of extremely overweight young adults--the GOYA study. / Paternoster, Lavinia; Evans, David M; Nohr, Ellen Aagaard; Holst, Claus; Gaborieau, Valerie; Brennan, Paul; Gjesing, Anette Prior; Grarup, Niels; Witte, Daniel R; Jørgensen, Torben; Linneberg, Allan René; Lauritzen, Torsten; Sandbaek, Anelli; Hansen, Torben; Pedersen, Oluf Borbye; Elliott, Katherine S; Kemp, John P; St Pourcain, Beate; McMahon, George; Zelenika, Diana; Hager, Jörg; Lathrop, Mark; Timpson, Nicholas J; Smith, George Davey; Sørensen, Thorkild I A.

    In: P L o S One, Vol. 6, No. 9, e24303, 2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B. / Hribal, M L; Presta, I; Procopio, T; Marini, M A; Stancáková, A; Kuusisto, J; Andreozzi, F; Hammarstedt, A; Jansson, P-A; Grarup, N; Hansen, T; Walker, M; Stefan, N; Fritsche, A; Häring, H U; Pedersen, O; Smith, U; Laakso, M; Sesti, G; EUGENE2 Consortium.

    In: Diabetologia, Vol. 54, No. 4, 2011, p. 795-802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1. / Torekov, S S; Ma, L; Grarup, N; Hartmann, B; Hainerová, I A; Kielgast, U; Kissow, H; Rosenkilde, M; Lebl, J; Witte, D R; Jørgensen, T; Sandbaek, A; Lauritzen, T; Madsen, O D; Wang, J; Linneberg, A; Madsbad, S; Holst, J J; Hansen, T; Pedersen, O; GIANT Consortium.

    In: Diabetologia, Vol. 54, No. 11, 2011, p. 2820-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes. / Engelen, Lian; Lund, Søren S; Ferreira, Isabel; Tarnow, Lise; Parving, Hans-Henrik; Gram, Jørgen; Hansen, Kaj Flemming Winther; Pedersen, Oluf; Teerlink, Tom; Barto, Rob; Stehouwer, Coen D A; Vaag, Allan A; Schalkwijk, Casper G.

    In: European Journal of Endocrinology, Vol. 164, No. 3, 2011, p. 371-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation. / Fredheim, Siri; Svensson, Jannet; Pørksen, Sven; Hansen, Lars; Hansen, Torben; Pedersen, Oluf Borbye; Mortensen, Henrik Bindesbøl; Barbetti, Fabrizio; Nielsen, Lotte Brøndum.

    In: Case Reports in Genetics, Vol. 2011, 2011, p. 258978.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test. / Møller, Jonas B; Jusko, William J; Gao, Wei; Hansen, Torben; Pedersen, Oluf; Holst, Jens J; Overgaard, Rune Viig; Madsen, Henrik; Ingwersen, Steen H.

    In: Journal of Pharmacokinetics and Pharmacodynamics, Vol. 38, No. 6, 2011, p. 713-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome. / Lohmueller, Kirk E; Albrechtsen, Anders; Li, Yingrui; Kim, Su Yeon; Korneliussen, Thorfinn Sand; Vinckenbosch, Nicolas; Tian, Geng; Huerta-Sanchez, Emilia; Feder, Alison F; Grarup, Niels; Jørgensen, Torben; Jiang, Tao; Witte, Daniel R; Sandbæk, Annelli; Hellmann, Ines; Lauritzen, Torsten; Hansen, Torben; Pedersen, Oluf; Wang, Jun; Nielsen, Rasmus.

    In: P L o S Genetics, Vol. 7, No. 10, 2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans. / Burgdorf, Kristoffer Sølvsten; Grarup, Niels; Justesen, Johanne Marie; Harder, Marie Neergaard; Witte, Daniel Rinse; Jørgensen, Torben; Sandbæk, Annelli; Lauritzen, Torsten; Madsbad, Sten; Hansen, Torben; DIAGRAM Consortium ; Pedersen, Oluf.

    In: P L o S One, Vol. 6, No. 1, 2011, p. e15813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals. / Grarup, N; Overvad, M; Sparsø, T; Witte, D R; Pisinger, C; Jørgensen, Torben; Yamauchi, T; Hara, K; Maeda, S; Kadowaki, T; Hansen, T; Pedersen, Oluf.

    In: Diabetologica, Vol. 54, No. 4, 2011, p. 789-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The effects of adding group-based lifestyle counselling to individual counselling on changes in plasma glucose levels in a randomized controlled trial : the Inter99 study. / Lau, C; Vistisen, Dorte; Toft, U; Tetens, Inge; Glümer, C; Pedersen, Oluf; Jørgensen, T; Borch-Johnsen, Knut.

    In: Diabetes & Metabolism, Vol. 37, No. 6, 2011, p. 546-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2010
  42. Published

    Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations. / Pruhova, Stepanka; Dusatkova, Petra; Sumnik, Zdenek; Kolouskova, Stanislava; Pedersen, Oluf; Hansen, Torben; Cinek, Ondrej; Lebl, Jan.

    In: Pediatric Diabetes Online, Vol. 11, No. 8, 01.12.2010, p. 529-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes. / Pilgaard, K; Færch, K; Carstensen, B; Poulsen, P; Pisinger, C; Pedersen, Oluf; Witte, D R; Hansen, T; Jørgensen, Torben; Vaag, A.

    In: Diabetologia, Vol. 53, No. 12, 01.12.2010, p. 2526-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. / Speliotes, Elizabeth K; Willer, Cristen J; Berndt, Sonja I; Monda, Keri L; Thorleifsson, Gudmar; Jackson, Anne U; Allen, Hana Lango; Lindgren, Cecilia M; Luan, Jian'an; Mägi, Reedik; Randall, Joshua C; Vedantam, Sailaja; Winkler, Thomas W; Lu, Qi; Workalemahu, Tsegaselassie; Heid, Iris M; Steinthorsdottir, Valgerdur; Stringham, Heather M; Weedon, Michael N; Wheeler, Eleanor; Wood, Andrew R; Ferreira, Teresa; Weyant, Robert J; Segrè, Ayellet V; Estrada, Karol; Liang, Liming; Nemesh, James; Park, Ju-Hyun; Gustafsson, Stefan; Oskari Kilpeläinen, Tuomas; Yang, Jian; Bouatia-Naji, Nabila; Esko, Tõnu; Feitosa, Mary F; Kutalik, Zoltán; Mangino, Massimo; Raychaudhuri, Soumya; Scherag, Andre; Smith, Albert Vernon; Welch, Ryan; Zhao, Jing Hua; Aben, Katja K; Absher, Devin M; Amin, Najaf; Dixon, Anna L; Gjesing, Anette P; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; MAGIC.

    In: Nature Genetics, Vol. 42, No. 11, 01.11.2010, p. 937-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. / Heid, Iris M; Jackson, Anne U; Randall, Joshua C; Winkler, Thomas W; Qi, Lu; Steinthorsdottir, Valgerdur; Thorleifsson, Gudmar; Zillikens, M Carola; Speliotes, Elizabeth K; Mägi, Reedik; Workalemahu, Tsegaselassie; White, Charles C; Bouatia-Naji, Nabila; Harris, Tamara B; Berndt, Sonja I; Ingelsson, Erik; Willer, Cristen J; Weedon, Michael N; Luan, Jian'an; Vedantam, Sailaja; Esko, Tõnu; Oskari Kilpeläinen, Tuomas; Kutalik, Zoltán; Li, Shengxu; Monda, Keri L; Dixon, Anna L; Holmes, Christopher C; Kaplan, Lee M; Liang, Liming; Min, Josine L; Moffatt, Miriam F; Molony, Cliona; Nicholson, George; Schadt, Eric E; Zondervan, Krina T; Feitosa, Mary F; Ferreira, Teresa; Allen, Hana Lango; Weyant, Robert J; Wheeler, Eleanor; Wood, Andrew R; Estrada, Karol; Goddard, Michael E; Lettre, Guillaume; Mangino, Massimo; Gjesing, Anette P; Witte, Daniel R; Hansen, Torben; Jørgensen, Torben; Pedersen, Oluf; MAGIC.

    In: Nature Genetics, Vol. 42, No. 11, 01.11.2010, p. 949-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. / Yamauchi, Toshimasa; Hara, Kazuo; Maeda, Shiro; Yasuda, Kazuki; Takahashi, Atsushi; Horikoshi, Momoko; Nakamura, Masahiro; Fujita, Hayato; Grarup, Niels; Cauchi, Stephane; Ng, Daniel P K; Ma, Ronald C W; Tsunoda, Tatsuhiko; Kubo, Michiaki; Watada, Hirotaka; Maegawa, Hiroshi; Okada-Iwabu, Miki; Iwabu, Masato; Shojima, Nobuhiro; Shin, Hyoung Doo; Andersen, Gitte; Witte, Daniel R; Jørgensen, Torben; Lauritzen, Torsten; Sandbæk, Annelli; Hansen, Torben; Ohshige, Toshihiko; Omori, Shintaro; Saito, Ikuo; Kaku, Kohei; Hirose, Hiroshi; So, Wing-Yee; Beury, Delphine; Chan, Juliana C N; Park, Kyong Soo; Tai, E Shyong; Ito, Chikako; Tanaka, Yasushi; Kashiwagi, Atsunori; Kawamori, Ryuzo; Kasuga, Masato; Froguel, Philippe; Pedersen, Oluf; Kamatani, Naoyuki; Nakamura, Yusuke; Kadowaki, Takashi.

    In: Nature Genetics, Vol. 42, No. 10, 01.10.2010, p. 864-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight. / Andersson, E A; Pilgaard, K; Pisinger, C; Harder, M N; Grarup, N; Faerch, K; Poulsen, P; Witte, D R; Jørgensen, Torben; Vaag, A; Hansen, T; Pedersen, Oluf.

    In: Diabetologia, Vol. 53, No. 9, 01.09.2010, p. 1908-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. / Gretarsdottir, Solveig; Baas, Annette F; Thorleifsson, Gudmar; Holm, Hilma; den Heijer, Martin; de Vries, Jean-Paul P M; Kranendonk, Steef E; Zeebregts, Clark J A M; van Sterkenburg, Steven M; Geelkerken, Robert H; van Rij, Andre M; Williams, Michael J A; Boll, Albert P M; Kostic, Jelena P; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Walters, G Bragi; Masson, Gisli; Sulem, Patrick; Saemundsdottir, Jona; Mouy, Magali; Magnusson, Kristinn P; Tromp, Gerard; Elmore, James R; Sakalihasan, Natzi; Limet, Raymond; Defraigne, Jean-Olivier; Ferrell, Robert E; Ronkainen, Antti; Ruigrok, Ynte M; Wijmenga, Cisca; Grobbee, Diederick E; Shah, Svati H; Granger, Christopher B; Quyyumi, Arshed A; Vaccarino, Viola; Patel, Riyaz S; Zafari, A Maziar; Levey, Allan I; Austin, Harland; Girelli, Domenico; Pignatti, Pier Franco; Olivieri, Oliviero; Martinelli, Nicola; Malerba, Giovanni; Trabetti, Elisabetta; Becker, Lewis C; Becker, Diane M; Reilly, Muredach P; Rader, Daniel J; Mueller, Thomas; Dieplinger, Benjamin; Haltmayer, Meinhard; Urbonavicius, Sigitas; Lindblad, Bengt; Gottsäter, Anders; Gaetani, Eleonora; Pola, Roberto; Wells, Philip; Rodger, Marc; Forgie, Melissa; Langlois, Nicole; Corral, Javier; Vasquez, Vicente; Fontcuberta, Jordi; España, Francisco; Grarup, Niels; Jørgensen, Torben; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf; Aben, Katja K; de Graaf, Jacqueline; Holewijn, Suzanne; Folkersen, Lasse; Franco-Cereceda, Anders; Eriksson, Per; Collier, David A; Stefansson, Hreinn; Steinthorsdottir, Valgerdur; Rafnar, Thorunn; Valdimarsson, Einar M; Magnadottir, Hulda B; Sveinbjornsdottir, Sigurlaug; Olafsson, Isleifur; Magnusson, Magnus Karl; Palmason, Robert; Haraldsdottir, Vilhelmina; Andersen, Karl; Onundarson, Pall T; Thorgeirsson, Gudmundur; Kiemeney, Lambertus A; Powell, Janet T; Carey, David J; Kuivaniemi, Helena; Lindholt, Jes S.; Jones, Gregory T; Kong, Augustine; Blankensteijn, Jan D; Matthiasson, Stefan E; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 42, No. 8, 01.08.2010, p. 692-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people. / Boesgaard, T W; Grarup, N; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, T; Pedersen, Oluf; Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC).

    In: Diabetologia, Vol. 53, No. 8, 01.08.2010, p. 1647-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation. / Wegner, L; Anthonsen, S; Bork-Jensen, Jette; Dalgaard, L; Hansen, T; Pedersen, O; Poulsen, P; Vaag, A.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 8, 08.2010, p. 3884-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes. / Burgdorf, Kristoffer Sølvsten; Sandholt, Camilla Helene; Sparsø, Thomas; Andersen, Gitte; Witte, Daniel R; Jørgensen, Torben; Sandbaek, Anelli; Lauritzen, Torsten; Sørensen, Thorkild I A; Madsbad, Sten; Hansen, Torben; Pedersen, Oluf.

    In: European Journal of Endocrinology, Vol. 163, No. 1, 01.07.2010, p. 81-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. / Voight, Benjamin F; Scott, Laura J; Steinthorsdottir, Valgerdur; Morris, Andrew P; Dina, Christian; Welch, Ryan P; Zeggini, Eleftheria; Huth, Cornelia; Aulchenko, Yurii S; Thorleifsson, Gudmar; McCulloch, Laura J; Ferreira, Teresa; Grallert, Harald; Amin, Najaf; Wu, Guanming; Willer, Cristen J; Raychaudhuri, Soumya; McCarroll, Steve A; Langenberg, Claudia; Hofmann, Oliver M; Dupuis, Josée; Qi, Lu; Segrè, Ayellet V; van Hoek, Mandy; Navarro, Pau; Ardlie, Kristin; Balkau, Beverley; Benediktsson, Rafn; Bennett, Amanda J; Blagieva, Roza; Boerwinkle, Eric; Bonnycastle, Lori L; Bengtsson Boström, Kristina; Bravenboer, Bert; Bumpstead, Suzannah; Burtt, Noisël P; Charpentier, Guillaume; Chines, Peter S; Cornelis, Marilyn; Couper, David J; Crawford, Gabe; Doney, Alex S F; Elliott, Katherine S; Elliott, Amanda L; Erdos, Michael R; Grarup, Niels; Jørgensen, Torben; Sparsø, Thomas; Hansen, Torben; Pedersen, Oluf; MAGIC investigators.

    In: Nature Genetics, Vol. 42, No. 7, 01.07.2010, p. 579-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. / Saxena, Richa; Hivert, Marie-France; Langenberg, Claudia; Tanaka, Toshiko; Pankow, James S; Vollenweider, Peter; Lyssenko, Valeriya; Bouatia-Naji, Nabila; Dupuis, Josée; Jackson, Anne U; Kao, W H Linda; Li, Man; Glazer, Nicole L; Manning, Alisa K; Luan, Jian'an; Stringham, Heather M; Prokopenko, Inga; Johnson, Toby; Grarup, Niels; Boesgaard, Trine W; Lecoeur, Cécile; Shrader, Peter; O'Connell, Jeffrey; Ingelsson, Erik; Couper, David J; Rice, Kenneth; Song, Kijoung; Andreasen, Camilla H; Dina, Christian; Köttgen, Anna; Le Bacquer, Olivier; Pattou, François; Taneera, Jalal; Steinthorsdottir, Valgerdur; Rybin, Denis; Ardlie, Kristin; Sampson, Michael; Qi, Lu; van Hoek, Mandy; Weedon, Michael N; Aulchenko, Yurii S; Voight, Benjamin F; Grallert, Harald; Balkau, Beverley; Bergman, Richard N; Borch-Johnsen, Knut; Jørgensen, Torben; Sparsø, Thomas; Hansen, Torben; Pedersen, Oluf; GIANT Consortium.

    In: Nature Genetics, Vol. 42, No. 2, 01.02.2010, p. 142-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. / Dupuis, Josée; Langenberg, Claudia; Prokopenko, Inga; Saxena, Richa; Soranzo, Nicole; Jackson, Anne U; Wheeler, Eleanor; Glazer, Nicole L; Bouatia-Naji, Nabila; Gloyn, Anna L; Lindgren, Cecilia M; Mägi, Reedik; Morris, Andrew P; Randall, Joshua; Johnson, Toby; Elliott, Paul; Rybin, Denis; Thorleifsson, Gudmar; Steinthorsdottir, Valgerdur; Henneman, Peter; Grallert, Harald; Dehghan, Abbas; Hottenga, Jouke Jan; Franklin, Christopher S; Navarro, Pau; Song, Kijoung; Goel, Anuj; Perry, John R B; Egan, Josephine M; Lajunen, Taina; Grarup, Niels; Sparsø, Thomas; Doney, Alex; Voight, Benjamin F; Stringham, Heather M; Li, Man; Kanoni, Stavroula; Shrader, Peter; Cavalcanti-Proença, Christine; Kumari, Meena; Qi, Lu; Timpson, Nicholas J; Gieger, Christian; Zabena, Carina; Rocheleau, Ghislain; Ingelsson, Erik; An, Ping; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; DIAGRAM Consortium.

    In: Nature Genetics, Vol. 42, No. 2, 01.02.2010, p. 105-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes. / Maeda, Shiro; Kobayashi, Masa-aki; Araki, Shin-ichi; Babazono, Tetsuya; Freedman, Barry I; Bostrom, Meredith A; Cooke, Jessica N; Toyoda, Masao; Umezono, Tomoya; Tarnow, Lise; Hansen, Torben; Gaede, Peter; Jorsal, Anders; Ng, Daniel P K; Ikeda, Minoru; Yanagimoto, Toru; Tsunoda, Tatsuhiko; Unoki, Hiroyuki; Kawai, Koichi; Imanishi, Masahito; Suzuki, Daisuke; Shin, Hyoung Doo; Park, Kyong Soo; Kashiwagi, Atsunori; Iwamoto, Yasuhiko; Kaku, Kohei; Kawamori, Ryuzo; Parving, Hans-Henrik; Bowden, Donald W; Pedersen, Oluf; Nakamura, Yusuke.

    In: P L o S Genetics, Vol. 6, No. 2, 01.01.2010, p. e1000842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals. / Andersson, Ehm A; Pilgaard, Kasper; Pisinger, Charlotta; Harder, Marie N; Grarup, Niels; Færch, Kristine; Sandholt, Camilla; Poulsen, Pernille; Witte, Daniel R; Jørgensen, Torben; Vaag, Allan; Pedersen, Oluf; Hansen, Torben.

    In: P L o S One, Vol. 5, No. 12, 01.01.2010, p. e14190.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY). / Boesgaard, Trine W; Pruhova, Stepanka; Andersson, Ehm A; Cinek, Ondrej; Obermannova, Barbora; Lauenborg, Jeannet; Damm, Peter; Bergholdt, Regine; Pociot, Flemming; Pisinger, Charlotta; Barbetti, Fabrizio; Lebl, Jan; Pedersen, Oluf; Hansen, Torben.

    In: B M C Medical Genetics, Vol. 11, 01.01.2010, p. 42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians. / Linneberg, A; Gonzalez-Quintela, A; Vidal, C; Jørgensen, Torben; Fenger, M; Hansen, T; Pedersen, Oluf; Husemoen, L L N.

    In: Clinical and Experimental Allergy, Vol. 40, No. 1, 01.01.2010, p. 123-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population. / Husemoen, Lise Lotte N; Jørgensen, Torben; Borch-Johnsen, Knut; Hansen, Torben; Pedersen, Oluf; Linneberg, Allan.

    In: P L o S One, Vol. 5, No. 8, 01.01.2010, p. e11735.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    TCF7L2 rs7903146-macronutrient interaction in obese individuals' responses to a 10-wk randomized hypoenergetic diet. / Grau, Katrine; Cauchi, Stephane; Holst, Claus; Astrup, Arne; Martinez, J. Alfredo; Saris, Wim H.M.; Blaak, Ellen E; Oppert, Jean-Michel; Arner, Peter; Rössner, Stephan; Macdonald, Ian A.; Klimcakova, Eva; Langin, Dominique; Pedersen, Oluf; Froguel, Philippe; Sørensen, Thorkild I.A.

    In: American Journal of Clinical Nutrition, Vol. 91, No. 2, 2010, p. 472-479.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    A human gut microbial gene catalogue established by metagenomic sequencing. / MetaHIT Consortium.

    In: Nature, Vol. 464, No. 7285, 2010, p. 59-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Combined analyses of 20 common obesity susceptibility variants. / Sandholt, Camilla Helene; Sparsø, Thomas; Grarup, Niels; Albrechtsen, Anders; Almind, Katrine; Hansen, Lars; Toft, Ulla; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 59, No. 7, 2010, p. 1667-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure. / Kring, Sofia Inez Iqbal; Holst, C.; Toubro, S.; Astrup, Arne; Hansen, T.; Pedersen, Oluf; Sørensen, Thorkild I.A.

    In: International Journal of Obesity, Vol. 34, No. 1, 2010, p. 182-189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Common variants near MC4R in relation to body fat, body fat distribution, metabolic traits and energy expenditure. / Kring, Sofia Inez Iqbal; Holst, C; Toubro, Søren; Astrup, Arne; Hansen, Torben; Pedersen, Oluf Borbye; Sørensen, T I A.

    In: International Journal of Obesity, Vol. 34, No. 1, 2010, p. 182-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Design of association studies with pooled or un-pooled next-generation sequencing data. / Kim, Su Yeon; Li, Yingrui; Guo, Yiran; Li, Ruiqiang; Holmkvist, Johan; Hansen, Torben; Pedersen, Oluf Borbye; Wang, Jun; Nielsen, Rasmus.

    In: Genetic Epidemiology, Vol. 34, No. 5, 2010, p. 479-491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity. / Gjesing, Anette P.; Larsen, Lesli Hingstrup; Torekov, Signe Sørensen; Hainerová, Irena Aldhoon; Kapur, Rahul; Johansen, Anders; Albrechtsen, Anders; Boj, Sylvia; Holst, Birgitte; Harper, Angela; Urhammer, Søren A.; Borch-Johnsen, Knut; Pisinger, Charlotta Holm; Echwald, Søren M; Eiberg, Hans Rudolf Lytchoff; Astrup, Arne; Lebl, Jan; Ferrer, Jorge; Schwartz, Thue W.; Hansen, Torben; Pedersen, Oluf.

    In: P L o S One, Vol. 5, No. 4, 2010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus. / Okamoto, Koji; Iwasaki, Naoko; Nishimura, Chisa; Doi, Kent; Noiri, Eisei; Nakamura, Shinko; Takizawa, Miho; Ogata, Makiko; Fujimaki, Risa; Grarup, Niels; Pisinger, Charlotta; Borch-Johnsen, Knut; Lauritzen, Torsten; Sandbaek, Annelli; Hansen, Torben; Yasuda, Kazuki; Osawa, Haruhiko; Nanjo, Kishio; Kadowaki, Takashi; Kasuga, Masato; Pedersen, Oluf; Fujita, Toshiro; Kamatani, Naoyuki; Iwamoto, Yasuhiko; Tokunaga, Katsushi.

    In: American Journal of Human Genetics, Vol. 86, No. 1, 2010, p. 54-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle. / Ribel-Madsen, Rasmus; Poulsen, Pernille; Holmkvist, Johan; Mortensen, Brynjulf; Grarup, Niels; Friedrichsen, Martin; Jørgensen, Torben; Lauritzen, Torsten; Wojtaszewski, Jørgen; Pedersen, Oluf; Hansen, Torben; Vaag, Allan.

    In: Diabetes, Vol. 59, No. 4, 2010, p. 1108-1112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Impact of size at birth and prematurity on adult anthropometry in 4744 middle-aged Danes - The Inter99 Study. / Pilgaard, K; Færch, K; Poulsen, P; Larsen, C.; Andersson, Ehm Astrid; Pisinger, Charlotta Holm; Toft, U.; Aadahl, M.; Pedersen, Oluf; Hansen, Torben; Jørgensen, Torben; Borch-Johnsen, Knut; Vaag, Allan.

    In: Journal of Developmental Origins of Health and Disease, Vol. 1, No. 5, 2010, p. 319-328.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans. / Andersson, Ehm A; Holst, Birgitte; Sparsø, Thomas; Grarup, Niels; Banasik, Karina; Holmkvist, Johan; Jørgensen, Torben; Borch-Johnsen, Knut; Egerod, Kristoffer L; Lauritzen, Torsten; Sørensen, Thorkild I A; Bonnefond, Amélie; Meyre, David; Froguel, Philippe; Schwartz, Thue W; Pedersen, Oluf; Hansen, Torben.

    In: Diabetes, Vol. 59, No. 6, 2010, p. 1539-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese europeans : The NUGENOB Study. / Corpeleijn, Eva; Petersen, Liselotte; Holst, Claus; Saris, Wim H.; Astrup, Arne; Langin, Dominique; Macdonald, Ian; Martinez, J. Alfredo; Oppert, Jean-Michel; Polak, Jan; Pedersen, Oluf Borbye; Froguel, Philippe; Arner, Peter; Sørensen, Thorkild I.A.; Blaak, Ellen E.

    In: Obesity, Vol. 18, No. 7, 2010, p. 1369-1377.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. / Li, Yingrui; Vinckenbosch, Nicolas; Tian, Geng; Huerta-Sanchez, Emilia; Jiang, Tao; Jiang, Hui; Albrechtsen, Anders; Andersen, Gitte; Cao, Hongzhi; Korneliussen, Thorfinn Sand; Grarup, Niels; Guo, Yiran; Hellman, Ines; Jin, Xin; Li, Qibin; Liu, Jiangtao; Liu, Xiao; Sparsø, Thomas; Tang, Meifang; Wu, Honglong; Wu, Renhua; Yu, Chang; Zheng, Hancheng; Astrup, Arne; Bolund, Lars; Holmkvist, Johan; Jørgensen, Torben; Kristiansen, Karsten; Schmitz, Ole; Schwartz, Thue W; Zhang, Xiuqing; Li, Ruiqiang; Yang, Huanming; Wang, Jian; Hansen, Torben; Pedersen, Oluf; Nielsen, Rasmus; Wang, Jun.

    In: Nature Genetics, Vol. 42, No. 11, 2010, p. 969-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest. / Alibegovic, Amra C; Sonne, Mette P; Højbjerre, Lise; Hansen, Torben; Pedersen, Oluf; van Hall, Gerrit; Holst, Jens J; Stallknecht, Bente; Dela, Flemming; Vaag, Allan.

    In: Diabetes, Vol. 59, No. 4, 2010, p. 836-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. 2009
  75. Published

    Erratum : Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia (Nature Genetics) 41 (1110-1115). / Rung, Johan; Cauchi, Stéphane; Albrechtsen, Anders; Shen, Lishuang; Rocheleau, Ghislain; Cavalcanti-Proença, Christine; Bacot, François; Balkau, Beverley; Belisle, Alexandre; Borch-Johnsen, Knut; Charpentier, Guillaume; Dina, Christian; Durand, Emmanuelle; Elliott, Paul; Hadjadj, Samy; Järvelin, Marjo Riitta; Laitinen, Jaana; Lauritzen, Torsten; Marre, Michel; Mazur, Alexander; Meyre, David; Montpetit, Alexandre; Pisinger, Charlotta; Posner, Barry; Poulsen, Pernille; Pouta, Anneli; Prentki, Marc; Ribel-Madsen, Rasmus; Ruokonen, Aimo; Sandbaek, Anelli; Serre, David; Tichet, Jean; Vaxillaire, Martine; Wojtaszewski, Jørgen F.P.; Vaag, Allan; Hansen, Torben; Polychronakos, Constantin; Pedersen, Oluf; Froguel, Philippe; Sladek, Robert.

    In: Nature Genetics, Vol. 41, No. 10, 01.10.2009.

    Research output: Contribution to journalComment/debateResearchpeer-review

  76. Published

    Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes. / Clausen, Tine D; Mathiesen, Elisabeth R; Hansen, Torben; Pedersen, Oluf Borbye; Jensen, Dorte M; Lauenborg, Jeannet; Schmidt, Lone; Damm, Peter; Clausen, Tine Dalsgaard; Mathiesen, Elisabeth R; Hansen, Torben; Pedersen, Oluf; Jensen, Dorte; Lauenborg, Jeannet; Schmidt, Lone; Damm, Peter.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 7, 01.07.2009, p. 2464-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men. / Pilgaard, K; Jensen, C; Schou, J; Lyssenko, V; Wegner, L; Brøns, C; Vilsbøll, T; Hansen, T; Madsbad, S; Holst, J; Vølund, A; Poulsen, P; Groop, L; Pedersen, Oluf; Vaag, A; Pilgaard, K; Jensen, C B; Schou, J H; Lyssenko, V; Wegner, L; Brøns, C; Vilsbøll, Tina; Hansen, T; Madsbad, S; Holst, Jens Møller; Vølund, Anders; Poulsen, P; Groop, L; Pedersen, O; Vaag, Allan.

    In: Diabetologia, Vol. 52, No. 7, 01.07.2009, p. 1298-307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Common type 2 diabetes risk gene variants associate with gestational diabetes. / Lauenborg, Jeannet; Grarup, Niels; Damm, Peter; Borch-Johnsen, Knut; Jørgensen, Torben; Pedersen, Oluf; Hansen, Torben; Lauenborg, Jeannet; Grarup, Niels; Damm, Peter; Borch-Johnsen, Knut; Jørgensen, Torben; Pedersen, Oluf; Hansen, Torben.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 1, 01.01.2009, p. 145-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads. / Rose, C S; Grarup, N; Krarup, N T; Poulsen, P; Wegner, L; Nielsen, Trine; Banasik, K; Faerch, K; Andersen, G; Albrechtsen, A; Borch-Johnsen, K; Clausen, J O; Jørgensen, T; Vaag, A; Pedersen, O; Hansen, T.

    In: Diabetologia, Vol. 52, No. 10, 2009, p. 2122-2129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. / Bouatia-Naji, Nabila; Bonnefond, Amélie; Cavalcanti-Proença, Christine; Sparsø, Thomas; Holmkvist, Johan; Marchand, Marion; Delplanque, Jérôme; Lobbens, Stéphane; Rocheleau, Ghislain; Durand, Emmanuelle; De Graeve, Franck; Chèvre, Jean-Claude; Borch-Johnsen, Knut; Hartikainen, Anna-Liisa; Ruokonen, Aimo; Tichet, Jean; Marre, Michel; Weill, Jacques; Heude, Barbara; Tauber, Maithé; Lemaire, Katleen; Schuit, Frans; Elliott, Paul; Jørgensen, Torben; Charpentier, Guillaume; Hadjadj, Samy; Cauchi, Stéphane; Vaxillaire, Martine; Sladek, Robert; Visvikis-Siest, Sophie; Balkau, Beverley; Lévy-Marchal, Claire; Pattou, François; Meyre, David; Blakemore, Alexandra I F; Jarvelin, Marjo-Riita; Walley, Andrew J; Hansen, Torben; Dina, Christian; Pedersen, Oluf; Froguel, Philippe.

    In: Nature Genetics, Vol. 41, No. 1, 2009, p. 89-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults. / Rathcke, Camilla Noelle; Holmkvist, Johan; Husmoen, Lise Lotte N; Hansen, Torben; Pedersen, Oluf; Vestergaard, Henrik; Linneberg, Allan René.

    In: PLoS ONE, Vol. 4, No. 7, 2009, p. e6106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid. / Vestergard, A.; Bredahl, K.; Muckadell, O.B. de; Pedersen, Oluf; Hansen, J.M.

    In: Ugeskrift for læger, Vol. 171, No. 4, 2009, p. 235-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction. / Sparsø, T; Grarup, N; Andreasen, C.; Albrechtsen, A; Holmkvist, J; Andersen, G; Jørgensen, Torben; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Madsbad, S; Hansen, T; Pedersen, Oluf; Sparsø, T; Grarup, N; Andreasen, C; Albrechtsen, A; Holmkvist, J; Andersen, G; Jørgensen, T; Borch-Johnsen, K; Sandbaek, A; Lauritzen, T; Madsbad, S; Hansen, T; Pedersen, O.

    In: Diabetologia, Vol. 52, No. 7, 2009, p. 1308-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial. / Lund, Søren S; Tarnow, Lise; Frandsen, Merete; Nielsen, Bente B; Hansen, Birgitte V; Pedersen, Oluf; Parving, Hans-Henrik; Vaag, Allan A.

    In: BMJ. British Medical Journal (International Ed.), Vol. 339, 2009, p. b4324.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99 cohort. / Kolberg, Janice A; Jørgensen, Torben; Gerwien, Robert W; Hamren, Sarah; McKenna, Michael P; Moler, Edward; Rowe, Michael W; Urdea, Mickey S; Xu, Xiaomei M; Hansen, Torben; Pedersen, Oluf; Borch-Johnsen, Knut.

    In: Diabetes Care, Vol. 32, No. 7, 2009, p. 1207-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Diabetes in infants may be treated with sulfonylurea as a replacement for insulin. / Lauridsen, M.H.; Boesgaard, T.W.; Pedersen, Oluf; Hansen, T.; Hertz, B.

    In: Ugeskrift for læger, Vol. 171, No. 23, 2009, p. 1923-1924.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults. / Lau, Cathrine; Toft, Ulla; Tetens, Inge; Carstensen, Bendix; Jørgensen, Torben; Pedersen, Oluf Borbye; Borch-Johnsen, Knut.

    In: Journal of Nutrition, Vol. 139, No. 3, 2009, p. 588-593.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men. / Zimmermann, Esther; Kring, Sofia I I; Berentzen, Tina L; Holst, Claus; Pers, Tune H; Hansen, Torben; Pedersen, Oluf; Sørensen, Thorkild I A; Jess, Tine.

    In: PLoS ONE, Vol. 4, No. 2, 2009, p. e4428.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Functional SOCS1 polymorphisms are associated with variation in obesity in whites. / Gylvin, T; Ek, J; Nolsøe, R.; Albrechtsen, A.; Andersen, G; Bergholdt, R.; Brorsson, C; Bang-Berthelsen, C. H.; Hansen, T.; Karlsen, A. E.; Billestrup, N; Borch-Johnsen, K; Jørgensen, Torben; Pedersen, Oluf; Mandrup-Poulsen, T; Nerup, J.; Pociot, Flemming Michael.

    In: Diabetes, Obesity and Metabolism, Vol. 11, No. 3, 2009, p. 196-203.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans. / Sparsø, Thomas; Bonnefond, Amélie; Andersson, Ehm; Bouatia-Naji, Nabila; Holmkvist, Johan; Wegner, Lise; Grarup, Niels; Gjesing, Anette P; Banasik, Karina; Cavalcanti-Proença, Christine; Marchand, Marion; Vaxillaire, Martine; Charpentier, Guillaume; Jarvelin, Marjo-Riitta; Tichet, Jean; Balkau, Beverley; Marre, Michel; Lévy-Marchal, Claire; Faerch, Kristine; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Poulsen, Pernille; Vaag, Allan; Dina, Christian; Hansen, Torben; Pedersen, Oluf; Froguel, Philippe; Sparsø, Thomas; Bonnefond, Amélie; Andersson, Ehm; Bouatia-Naji, Nabila; Holmkvist, Johan; Wegner, Lise; Grarup, Niels; Gjesing, Anette P; Banasik, Karina; Cavalcanti-Proença, Christine; Marchand, Marion; Vaxillaire, Martine; Charpentier, Guillaume; Jarvelin, Marjo-Riitta; Tichet, Jean; Balkau, Beverley; Marre, Michel; Lévy-Marchal, Claire; Faerch, Kristine; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Poulsen, Pernille; Vaag, Allan; Dina, Christian; Hansen, Torben; Pedersen, Oluf; Froguel, Philippe.

    In: Diabetes, Vol. 58, No. 6, 2009, p. 1450-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: The DAMAGE study. / Reiling, Erwin; van Vliet-Ostaptchouk, Jana V; van 't Riet, Esther; van Haeften, Timon W; Arp, Pascal A; Hansen, Torben; Kremer, Dennis; Groenewoud, Marlous J; van Hove, Els C; Romijn, Johannes A; Smit, Jan W A; Nijpels, Giel; Heine, Robert J; Uitterlinden, André G; Pedersen, Oluf; Slagboom, P Eline; Maassen, Johannes A; Hofker, Marten H; 't Hart, Leen M; Dekker, Jacqueline M.

    In: European Journal of Human Genetics, Vol. 17, No. 8, 2009, p. 1056-1062.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. / Perry, John R B; Weedon, Michael N; Langenberg, Claudia; Jackson, Anne U; Lyssenko, Valeriya; Sparsø, Thomas; Thorleifsson, Gudmar; Grallert, Harald; Ferrucci, Luigi; Maggio, Marcello; Paolisso, Giuseppe; Walker, Mark; Palmer, Colin N A; Payne, Felicity; Young, Elizabeth; Herder, Christian; Narisu, Narisu; Morken, Mario A; Bonnycastle, Lori L; Owen, Katharine R; Shields, Beverley; Knight, Beatrice; Bennett, Amanda; Groves, Christopher J; Ruokonen, Aimo; Jarvelin, Marjo Riitta; Pearson, Ewan; Pascoe, Laura; Ferrannini, Ele; Bornstein, Stefan R; Stringham, Heather M; Scott, Laura J; Kuusisto, Johanna; Nilsson, Peter; Neptin, Malin; Gjesing, Anette P; Pisinger, Charlotta; Lauritzen, Torsten; Sandbaek, Annelli; Sampson, Mike; Zeggini, Magic Ele; Lindgren, Cecilia M; Steinthorsdottir, Valgerdur; Thorsteinsdottir, Unnur; Hansen, Torben; Schwarz, Peter; Illig, Thomas; Laakso, Markku; Stefansson, Kari; Morris, Andrew D; Groop, Leif; Pedersen, Oluf; Boehnke, Michael; Barroso, Inês; Wareham, Nicholas J; Hattersley, Andrew T; McCarthy, Mark I; Frayling, Timothy M.

    In: Human Molecular Genetics, Vol. 19, No. 3, 2009, p. 535-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits. / Bonnefond, Amélie; Vaxillaire, Martine; Labrune, Yann; Lecoeur, Cécile; Chèvre, Jean-Claude; Bouatia-Naji, Nabila; Cauchi, Stéphane; Balkau, Beverley; Marre, Michel; Tichet, Jean; Riveline, Jean-Pierre; Hadjadj, Samy; Gallois, Yves; Czernichow, Sébastien; Hercberg, Serge; Kaakinen, Marika; Wiesner, Susanne; Charpentier, Guillaume; Lévy-Marchal, Claire; Elliott, Paul; Jarvelin, Marjo-Riitta; Horber, Fritz; Dina, Christian; Pedersen, Oluf; Sladek, Robert; Meyre, David; Froguel, Philippe.

    In: Diabetes, Vol. 58, No. 11, 2009, p. 2687-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. / Rung, Johan; Cauchi, Stéphane; Albrechtsen, Anders; Shen, Lishuang; Rocheleau, Ghislain; Cavalcanti-Proença, Christine; Bacot, François; Balkau, Beverley; Belisle, Alexandre; Borch-Johnsen, Knut; Charpentier, Guillaume; Dina, Christian; Durand, Emmanuelle; Elliott, Paul; Hadjadj, Samy; Järvelin, Marjo-Riitta; Laitinen, Jaana; Lauritzen, Torsten; Marre, Michel; Mazur, Alexander; Meyre, David; Montpetit, Alexandre; Pisinger, Charlotta; Posner, Barry; Poulsen, Pernille; Pouta, Anneli; Prentki, Marc; Ribel-Madsen, Rasmus; Ruokonen, Aimo; Sandbaek, Anelli; Serre, David; Tichet, Jean; Vaxillaire, Martine; Wojtaszewski, Jørgen; Vaag, Allan; Hansen, Torben; Polychronakos, Constantin; Pedersen, Oluf; Froguel, Philippe; Sladek, Robert.

    In: Nature Genetics, Vol. 41, No. 10, 2009, p. 1110-1115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. / Thorleifsson, Gudmar; Walters, G Bragi; Gudbjartsson, Daniel F; Steinthorsdottir, Valgerdur; Sulem, Patrick; Helgadottir, Anna; Styrkarsdottir, Unnur; Gretarsdottir, Solveig; Thorlacius, Steinunn; Jonsdottir, Ingileif; Jonsdottir, Thorbjorg; Olafsdottir, Elinborg J; Olafsdottir, Gudridur H; Jonsson, Thorvaldur; Jonsson, Frosti; Borch-Johnsen, Knut; Hansen, Torben; Andersen, Gitte; Jørgensen, Torben; Lauritzen, Torsten; Aben, Katja K; Verbeek, André L M; Roeleveld, Nel; Kampman, Ellen; Yanek, Lisa R; Becker, Lewis C; Tryggvadottir, Laufey; Rafnar, Thorunn; Becker, Diane M; Gulcher, Jeffrey; Kiemeney, Lambertus A; Pedersen, Oluf; Kong, Augustine; Thorsteinsdottir, Unnur; Stefansson, Kari.

    In: Nature Genetics, Vol. 41, No. 1, 2009, p. 18-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    IDENTIFICATION OF NOVEL VARIANTS IN THE HEPATOCYTE NUCLEAR FACTOR 1 ALPHA GENE IN SOUTH INDIAN PATIENTS WITH MATURITY ONSET DIABETES OF YOUNG. / Radha, V; Ek, J; Anuradha, S; Hansen, T; Pedersen, Oluf; Mohan, V.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 6, 2009, p. 1959-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Identification of novel variants in the hepatocyte nuclear factor-1alpha gene in South Indian patients with maturity onset diabetes of young. / Radha, V.; Ek, J.; Anuradha, S.; Hansen, T.; Pedersen, Oluf; Mohan, V.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 6, 2009, p. 1959-1965.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics. / Koutnikova, Hana; Laakso, Markku; Lu, Lu; Combe, Roy; Paananen, Jussi; Kuulasmaa, Teemu; Kuusisto, Johanna; Häring, Hans-Ulrich; Hansen, Torben; Pedersen, Oluf; Smith, Ulf; Hanefeld, Markolf; Williams, Robert W; Auwerx, Johan.

    In: PLoS Genetics, Vol. 5, No. 8, 2009, p. e1000591.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Increased recovery rates of phosphocreatine and inorganic phosphate after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in homozygous carriers of the A-allele of FTO rs9939609. / Grunnet, Louise Groth; Brøns, Charlotte; Jacobsen, Stine; Nilsson, Emma; Astrup, Arne; Hansen, Torben; Pedersen, Oluf; Poulsen, Pernille; Quistorff, Bjørn; Vaag, Allan.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2009, p. 596-602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention. / Meur, Gargi; Simon, Albane; Harun, Nasret; Virally, Marie; Dechaume, Aurélie; Bonnefond, Amélie; Fetita, Sabrina; Tarasov, Andrei I; Guillausseau, Pierre-Jean; Boesgaard, Trine Welløv; Pedersen, Oluf; Hansen, Torben; Polak, Michel; Gautier, Jean-François; Froguel, Philippe; Rutter, Guy A; Vaxillaire, Martine.

    In: Diabetes, Vol. 59, No. 3, 2009, p. 653-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Intensified multifactorial treatment of patients with Type 2 diabetes : what can be achieved and does it pay off? / Pedersen, Oluf.

    In: Journal of Diabetes, Vol. 1, No. 2, 2009, p. 83-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index. / Huth, Cornelia; Illig, Thomas; Herder, Christian; Gieger, Christian; Grallert, Harald; Vollmert, Caren; Rathmann, Wolfgang; Hamid, Yasmin; Pedersen, Oluf; Hansen, Torben; Thorand, Barbara; Meisinger, Christa; Doring, Angela; Klopp, Norman; Gohlke, Henning; Lieb, Wolfgang; Hengstenberg, Christian; Lyssenko, Valeriya; Groop, Leif; Ireland, Helen; Stephens, Jeffrey; Wernstedt Asterholm, Ingrid; Jansson, John-Olov; Boeing, Heiner; Mohlig, Matthias; Stringham, Heather; Boehnke, Michael; Tuomilehto, Jaakko; Fernandez-Real, Jose-Manuel; Lopez-Bermejo, Abel; Gallart, Luis; Vendrell, Joan; Humphries, Steve; Kronenberg, Florian; Wichmann, H-Erich; Heid, Iris.

    In: Annals of Medicine, Vol. 41, 2009, p. 128-38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index. / Huth, C.; Illig, T.; Herder, C.; Gieger, C.; Grallert, H.; Vollmert, C.; Rathmann, W.; Hamid, Y.H.; Pedersen, Oluf; Hansen, T.; Thorand, B.; Meisinger, C.; Doring, A.; Klopp, N.; Gohlke, H.; Lieb, W.; Hengstenberg, C.; Lyssenko, V.; Groop, L.; Ireland, H.; Stephens, J.W.; Asterholm, I. Wernstedt; Jansson, J.O.; Boeing, H.; Mohlig, M.; Stringham, H.M.; Boehnke, M.; Tuomilehto, J.; Fernandez-Real, J.M.; Lopez-Bermejo, A.; Gallart, L.; Vendrell, J.; Humphries, S.E.; Kronenberg, F.; Wichmann, H.E.; Heid, I.M.

    In: Annals of Medicine, Vol. 41, No. 2, 2009, p. 128-138.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Mutations in the VNTR of the carboxyl-ester lipase gene (CEL) are a rare cause of monogenic diabetes. / Torsvik, Janniche; Johansson, Stefan; Johansen, Anders; Ek, Jakob; Minton, Jayne; Raeder, Helge; Ellard, Sian; Hattersley, Andrew; Pedersen, Oluf; Hansen, Torben; Molven, Anders; Njølstad, Pål R.

    In: Human Genetics, Vol. 127, No. 1, 2009, p. 55-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 919113