Oluf Borbye Pedersen

Oluf Borbye Pedersen

Professor


  1. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young. / Østoft, Signe Harring; Bagger, Jonatan Ising; Hansen, Torben; Hartmann, Bolette; Pedersen, Oluf; Holst, Jens Juul; Knop, Filip Krag; Vilsbøll, Tina.

    In: European Journal of Endocrinology, Vol. 173, No. 2, 01.08.2015, p. 205-215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Discovery of novel heart rate-associated loci using the Exome Chip. / van den Berg, Marten E; Warren, Helen R; Cabrera, Claudia P; Verweij, Niek; Mifsud, Borbala; Haessler, Jeffrey; Bihlmeyer, Nathan A; Fu, Yi-Ping; Weiss, Stefan; Lin, Henry J; Grarup, Niels; Li-Gao, Ruifang; Pistis, Giorgio; Shah, Nabi; Brody, Jennifer A; Müller-Nurasyid, Martina; Lin, Honghuang; Mei, Hao; Smith, Albert V; Lyytikäinen, Leo-Pekka; Hall, Leanne M; van Setten, Jessica; Trompet, Stella; Prins, Bram P; Isaacs, Aaron; Radmanesh, Farid; Marten, Jonathan; Entwistle, Aiman; Kors, Jan A; Silva, Claudia T; Alonso, Alvaro; Bis, Joshua C; de Boer, Rudolf A; de Haan, Hugoline G; de Mutsert, Renée; Dedoussis, George; Dominiczak, Anna F; Doney, Alex S F; Ellinor, Patrick T; Eppinga, Ruben N; Felix, Stephan B; Guo, Xiuqing; Hagemeijer, Yanick; Hansen, Torben; Harris, Tamara B; Heckbert, Susan R; Huang, Paul L; Hwang, Shih-Jen; Kähönen, Mika; Kanters, Jørgen K; Kolcic, Ivana; Launer, Lenore J; Li, Man; Yao, Xiao Jie; Linneberg, Allan; Liu, Simin; Macfarlane, Peter W; Mangino, Massimo; Morris, Andrew D; Mulas, Antonella; Murray, Alison D; Nelson, Christopher P; Orrù, Marco; Padmanabhan, Sandosh; Peters, Annette; Porteous, David J; Poulter, Neil; Psaty, Bruce M; Qi, Lihong; Raitakari, Olli T; Rivadeneira, Fernando; Roselli, Carolina; Rudan, Igor; Sattar, Naveed; Sever, Peter; Sinner, Moritz F; Soliman, Elsayed Z; Spector, Timothy D.; Stanton, Alice V; Stirrups, Kathleen E; Taylor, Kent D; Tobin, Martin D; Uitterlinden, Andre; Vaartjes, Ilonca; Hoes, Arno W; van der Meer, Peter; Völker, Uwe; Waldenberger, Melanie; Xie, Zhijun; Zoledziewska, Magdalena; Tinker, Andrew; Polasek, Ozren; Rosand, Jonathan; Jamshidi, Yalda; van Duijn, Cornélia M; Zeggini, Eleftheria; Jukema, J Wouter; Asselbergs, Folkert W; Samani, Nilesh J; Lehtimäki, Terho; Gudnason, Vilmundur; Wilson, James; Lubitz, Steven A; Kääb, Stefan; Sotoodehnia, Nona; Caulfield, Mark J; Palmer, Colin N A; Sanna, Serena; Mook-Kanamori, Dennis O; Deloukas, Panos; Pedersen, Oluf; Rotter, Jerome I; Dörr, Marcus; O'Donnell, Chris J; Hayward, Caroline; Arking, Dan E; Kooperberg, Charles; van der Harst, Pim; Eijgelsheim, Mark; Stricker, Bruno H Ch; Munroe, Patricia B.

    In: Human Molecular Genetics, Vol. 26, No. 12, 15.06.2017, p. 2346-2363.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility : the DAMAGE study. / van Hove, Els C; Hansen, Torben; Dekker, Jacqueline M; Reiling, Erwin; Nijpels, Giel; Jørgensen, Torben; Borch-Johnsen, Knut; Hamid, Yasmin H; Heine, Robert J; Pedersen, Oluf; Maassen, J Antonie; hart, Leen M.

    In: Diabetes, Vol. 55, No. 11, 2006, p. 3193-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes. / Zobel, Dorit P; Andreasen, Camilla H; Grarup, Niels; Eiberg, Hans; Sørensen, Thorkild I A; Sandbæk, Annelli; Lauritzen, Torsten; Borch-Johnsen, Knut; Jørgensen, Torben; Pedersen, Oluf; Hansen, Torben.

    In: Diabetes, 2009, p. 757-764.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Variation in the gene encoding Kruppel-like factor 7 influences body fat: studies of 14,818 Danes. / Zobel, Dorit; Andreasen, Camilla; Burgdorf, Kristoffer; Andersson, Ehm; Sandbæk, Annelli; Lauritzen, Torsten; Borch-Johnsen, Knut; Jørgensen, Torben; Maeda, Shiro; Nakamura, Yusuke; Eiberg, Hans; Pedersen, Oluf; Hansen, Torben.

    In: European Journal of Endocrinology, Vol. 160, No. 4, 2009, p. 603-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men. / Zimmermann, Esther; Kring, Sofia I I; Berentzen, Tina L; Holst, Claus; Pers, Tune H; Hansen, Torben; Pedersen, Oluf; Sørensen, Thorkild I A; Jess, Tine.

    In: PLoS ONE, Vol. 4, No. 2, 2009, p. e4428.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans. / Zhang, Li; Bahl, Martin Iain; Roager, Henrik Munch; Fonvig, Cilius Esmann; Hellgren, Lars I; Frandsen, Henrik Lauritz; Pedersen, Oluf; Holm, Jens-Christian; Hansen, Torben; Licht, Tine Rask.

    In: The ISME Journal, Vol. 11, 18.11.2017, p. 676-690.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. / Zeggini, Eleftheria; Scott, Laura J; Saxena, Richa; Voight, Benjamin F; Marchini, Jonathan L; Hu, Tianle; de Bakker, Paul I W; Abecasis, Gonçalo R; Almgren, Peter; Andersen, Gitte; Ardlie, Kristin; Boström, Kristina Bengtsson; Bergman, Richard N; Bonnycastle, Lori L; Borch-Johnsen, Knut; Burtt, Noël P; Chen, Hong; Chines, Peter S; Daly, Mark J; Deodhar, Parimal; Ding, Chia-Jen; Doney, Alex S F; Duren, William L; Elliott, Katherine S; Erdos, Michael R; Frayling, Timothy M; Freathy, Rachel M; Gianniny, Lauren; Grallert, Harald; Grarup, Niels; Groves, Christopher J; Guiducci, Candace; Hansen, Torben; Herder, Christian; Hitman, Graham A; Hughes, Thomas E; Isomaa, Bo; Jackson, Anne U; Jørgensen, Torben; Kong, Augustine; Kubalanza, Kari; Kuruvilla, Finny G; Kuusisto, Johanna; Langenberg, Claudia; Lango, Hana; Lauritzen, Torsten; Li, Yun; Lindgren, Cecilia M; Lyssenko, Valeriya; Wellcome Trust Case Control Consortium ; Pedersen, Oluf.

    In: Nature Genetics, Vol. 40, No. 5, 2008, p. 638-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B. / Yamauchi, Toshimasa; Hara, Kazuo; Maeda, Shiro; Yasuda, Kazuki; Takahashi, Atsushi; Horikoshi, Momoko; Nakamura, Masahiro; Fujita, Hayato; Grarup, Niels; Cauchi, Stephane; Ng, Daniel P K; Ma, Ronald C W; Tsunoda, Tatsuhiko; Kubo, Michiaki; Watada, Hirotaka; Maegawa, Hiroshi; Okada-Iwabu, Miki; Iwabu, Masato; Shojima, Nobuhiro; Shin, Hyoung Doo; Andersen, Gitte; Witte, Daniel R; Jørgensen, Torben; Lauritzen, Torsten; Sandbæk, Annelli; Hansen, Torben; Ohshige, Toshihiko; Omori, Shintaro; Saito, Ikuo; Kaku, Kohei; Hirose, Hiroshi; So, Wing-Yee; Beury, Delphine; Chan, Juliana C N; Park, Kyong Soo; Tai, E Shyong; Ito, Chikako; Tanaka, Yasushi; Kashiwagi, Atsunori; Kawamori, Ryuzo; Kasuga, Masato; Froguel, Philippe; Pedersen, Oluf; Kamatani, Naoyuki; Nakamura, Yusuke; Kadowaki, Takashi.

    In: Nature Genetics, Vol. 42, No. 10, 01.10.2010, p. 864-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes. / Yaghootkar, Hanieh; Lamina, Claudia; Scott, Robert A; Dastani, Zari; Hivert, Marie-France; Warren, Liling L; Stancáková, Alena; Buxbaum, Sarah G; Lyytikäinen, Leo-Pekka; Henneman, Peter; Wu, Ying; Cheung, Chloe Yy; Pankow, James S; Jackson, Anne U; Gustafsson, Stefan; Zhao, Jing Hua; Ballantyne, Christie M; Xie, Weijia; Bergman, Richard N; Boehnke, Michael; El Bouazzaoui, Fatiha; Collins, Francis S; Dunn, Sandra H; Dupuis, Josee; Forouhi, Nita G; Gillson, Christopher; Hattersley, Andrew T; Hong, Jaeyoung; Kähönen, Mika; Kuusisto, Johanna; Kedenko, Lyudmyla; Kronenberg, Florian; Doria, Alessandro; Assimes, Themistocles L; Ferrannini, Ele; Hansen, Torben; Hao, Ke; Häring, Hans; Knowles, Joshua W; Lindgren, Cecilia M; Nolan, John J; Paananen, Jussi; Pedersen, Oluf; Quertermous, Thomas; Smith, Ulf; Lehtimäki, Terho; Liu, Ching-Ti; Loos, Ruth Jf; McCarthy, Mark I; Morris, Andrew D; the GENESIS consortium.

    In: Diabetes, Vol. 62, No. 10, 08.07.2013, p. 3589.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion. / Yaghootkar, Hanieh; Stancáková, Alena; Freathy, Rachel M; Vangipurapu, Jagadish; Weedon, Michael N; Xie, Weijia; Wood, Andrew R; Ferrannini, Ele; Mari, Andrea; Ring, Susan M; Lawlor, Debbie A; Davey Smith, George; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf; Steinthorsdottir, Valgerdur; Guðbjartsson, Daniel F; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Stefansson, Kari; Hattersley, Andrew T; Walker, Mark; Morris, Andrew D; McCarthy, Mark I; Palmer, Colin N A; Laakso, Markku; Frayling, Timothy M.

    In: Diabetes, Vol. 64, No. 6, 06.2015, p. 2279-85.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. / Xie, Weijia; Wood, Andrew R; Lyssenko, Valeriya; Weedon, Michael N; Knowles, Joshua W; Alkayyali, Sami; Assimes, Themistocles L; Quertermous, Thomas; Abbasi, Fahim; Paananen, Jussi; Häring, Hans; Hansen, Torben; Pedersen, Oluf; Smith, Ulf; Laakso, Markku; Dekker, Jacqueline M; Nolan, John J; Groop, Leif; Ferrannini, Ele; Adam, Klaus-Peter; Gall, Walter E; Frayling, Timothy M; Walker, Mark; MAGIC Investigators.

    In: Diabetes, Vol. 62, No. 6, 06.2013, p. 2141-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants. / Wood, Andrew R; Jonsson, Anna; Jackson, Anne U; Wang, Tian-Nan; van Leewen, Nienke; Palmer, Nicholette D; Kobes, Sayuko; Deelen, Joris; Boquete-Vilarino, Lorena; Paananen, Jussi; Stančáková, Alena; Boomsma, Dorret I; de Geus, Eco Jc; Eekhoff, Elisabeth Mw; Fritsche, Andreas; Kramer, Mark; Nijpels, Giel; Simonis-Bik, Annemarie M C; van Haeften, Timon W; Mahajan, Anubha; Boehnke, Michael; Bergman, Richard N; Tuomilehto, Jaakko; Collins, Francis S; Mohlke, Karen L; Banasik, Karina; Groves, Christopher J; McCarthy, Mark I; Pearson, Ewan R; Natali, Andrea; Mari, Andrea; Buchanan, Thomas A; Taylor, Kent D; Xiang, Anny H; Gjesing, Anette P; Grarup, Niels; Eiberg, Hans; Pedersen, Oluf; Chen, Yii-Derr; Laakso, Markku; Norris, Jill M; Smith, Ulf; Wagenknecht, Lynne E; Baier, Leslie; Bowden, Donald W; Hansen, Torben; Walker, Mark; Watanabe, Richard M; 't Hart, Leen M; Hanson, Robert L; Frayling, Timothy M.

    In: Diabetes, Vol. 66, No. 8, 2017, p. 2296-2309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes. / Winther, Signe A.; Øllgaard, Jens C.; Tofte, Nete; Tarnow, Lise; Wang, Zeneng; Ahluwalia, Tarunveer S.; Jorsal, Anders; Theilade, Simone; Parving, Hans-Henrik; Hansen, Tine W.; Hazen, Stanley L.; Pedersen, Oluf; Rossing, Peter.

    In: Diabetes Care, Vol. 42, No. 8, 2019, p. 1512-1520.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study. / Winkler, Thomas W; Justice, Anne E; Graff, Mariaelisa; Barata, Llilda; Feitosa, Mary F; Chu, Su; Czajkowski, Jacek; Esko, Tõnu; Fall, Tove; Kilpeläinen, Tuomas O; Lu, Yingchang; Mägi, Reedik; Mihailov, Evelin; Pers, Tune H; Rüeger, Sina; Teumer, Alexander; Ehret, Georg B; Ferreira, Teresa; Heard-Costa, Nancy L; Karjalainen, Juha; Lagou, Vasiliki; Mahajan, Anubha; Neinast, Michael D; Prokopenko, Inga; Simino, Jeannette; Teslovich, Tanya M; Jansen, Rick; Westra, Harm-Jan; White, Charles C; Absher, Devin; Ahluwalia, Tarun Veer Singh; Ahmad, Shafqat; Albrecht, Eva; Alves, Alexessander Couto; Bragg-Gresham, Jennifer L; de Craen, Anton J M; Bis, Joshua C; Bonnefond, Amélie; Boucher, Gabrielle; Banasik, Karina; Grarup, Niels; Hansen, Torben; Jørgensen, Torben; Krarup, Nikolaj T; Linneberg, Allan; Ribel-Madsen, Rasmus; Sparsø, Thomas H; Melbye, Mads; Pedersen, Oluf; Sørensen, Thorkild I A; CHARGE Consortium.

    In: P L o S Genetics, Vol. 11, No. 10, e1005378, 01.10.2015, p. 1-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration. / Wilman, Henry R.; Parisinos, Constantinos A.; Atabaki-Pasdar, Naeimeh; Kelly, Matt; Thomas, E. Louise; Neubauer, Stefan; Jennison, Christopher; Ehrhardt, B.; Baum, Patrick; Schoelsch, Corinna; Freijer, Jan; Grempler, Rolf; Graefe-Mody, Ulrike; Hennige, A.; Dings, Christiane; Lehr, Thorsten; Scherer, Nina; Sihinecich, I.; Pattou, Francois; Raverdi, Violeta; Caiazzo, Robert; Torres, Fanelly; Verkindt, Helene; Mari, Andrea; Tura, Andrea; Giorgino, Toni; Bizzotto; Froguel, Philippe; Brorsson, Caroline; Brunak, S.; De Masi, Federico; Pedersen, H.; Banasik, Karina; Thomas, Cecilia; Lundgaard, Agnete; Nielsen, A.; Mazzoni, Gianluca; Karaderi, T.; Rasmussen, S.; Johansen, Joachim; Allesøe, Rosa; Arumugam, Manimozhiyan; Allin, Kristine; Hansen, Torben; Hansen, Tue; Jonsson, Anna; Pedersen, Oluf; Dutta, Avirup; Vogt, J.; Vestergaard, Henrik; IMI-DIRECT consortium.

    In: Journal of Hepatology, Vol. 71, No. 3, 2019, p. 594-602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. / Willems, Sara M; et al. ; Grarup, Niels; Linneberg, Allan; Schnurr, Theresia M; Pedersen, Oluf; GEFOS Any-Type of Fracture Consortium ; Hansen, Torben.

    In: Nature Communications, Vol. 8, 16015, 12.07.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Evidence of a liver-alpha cell axis in humans : hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids. / Wewer Albrechtsen, Nicolai J; Færch, Kristine; Jensen, Troels M; Witte, Daniel R; Pedersen, Jens; Mahendran, Yuvaraj; Jonsson, Anna E; Galsgaard, Katrine D; Winther-Sørensen, Marie; Torekov, Signe S; Lauritzen, Torsten; Pedersen, Oluf; Knop, Filip K; Hansen, Torben; Jørgensen, Marit E; Vistisen, Dorte; Holst, Jens J.

    In: Diabetologia, Vol. 61, No. 3, 2018, p. 671-680.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. / Wessel, Jennifer; Chu, Audrey Y; Willems, Sara M; Wang, Shuai; Yaghootkar, Hanieh; Brody, Jennifer A; Dauriz, Marco; Hivert, Marie-France; Raghavan, Sridharan; Lipovich, Leonard; Hidalgo, Bertha; Fox, Keolu; Huffman, Jennifer E; An, Ping; Lu, Yingchang; Rasmussen-Torvik, Laura J; Grarup, Niels; Ehm, Margaret G; Li, Li; Baldridge, Abigail S; Stančáková, Alena; Abrol, Ravinder; Besse, Céline; Boland, Anne; Bork-Jensen, Jette; Fornage, Myriam; Freitag, Daniel F; Garcia, Melissa E; Guo, Xiuqing; Hara, Kazuo; Isaacs, Aaron; Jakobsdottir, Johanna; Lange, Leslie A; Layton, Jill C; Li, Man; Hua Zhao, Jing; Meidtner, Karina; Morrison, Alanna C; Nalls, Mike A; Peters, Marjolein J; Sabater-Lleal, Maria; Schurmann, Claudia; Silveira, Angela; Smith, Albert V; Southam, Lorraine; Allin, Kristine H; Jørgensen, Torben; Linneberg, Allan; Hansen, Torben; Pedersen, Oluf; EPIC-InterAct Consortium.

    In: Nature Communications, Vol. 6, 29.01.2015, p. 5897.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mutation analysis of the MCHR1 gene in human obesity. / Wermter, Anne-Kathrin; Reichwald, Kathrin; Büch, Thomas; Geller, Frank; Platzer, Cornelia; Huse, Klaus; Hess, Claudia; Remschmidt, Helmut; Gudermann, Thomas; Preibisch, Gerald; Siegfried, Wolfgang; Goldschmidt, Hans-Peter; Li, Wei-Dong; Price, R Arlen; Biebermann, Heike; Krude, Heiko; Vollmert, Caren; Wichmann, H-Erich; Illig, Thomas; Sørensen, Thorkild I A; Astrup, Arne; Larsen, Lesli Hingstrup; Pedersen, Oluf; Eberlé, Delphine; Clément, Karine; Blundell, John; Wabitsch, Martin; Schäfer, Helmut; Platzer, Matthias; Hinney, Anke; Hebebrand, Johannes.

    In: European Journal of Endocrinology, Vol. 152, No. 6, 2005, p. 851-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins. / Wegner, Lise; Hussain, Meena S; Pilgaard, Kasper; Hansen, Torben; Pedersen, Oluf; Vaag, Allan; Poulsen, Inge Pernille.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 10, 2008, p. 4013-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population : studies of 7,495 Danish whites. / Wegner, Lise; Andersen, Gitte; Sparsø, Thomas; Grarup, Niels; Glümer, Charlotte; Borch-Johnsen, Knut; Jørgensen, Torben; Hansen, Torben; Pedersen, Oluf.

    In: Diabetes, Vol. 56, No. 3, 2007, p. 694-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation. / Wegner, L; Anthonsen, S; Bork-Jensen, Jette; Dalgaard, L; Hansen, T; Pedersen, O; Poulsen, P; Vaag, A.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 8, 08.2010, p. 3884-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. / Michaelsen, Kim F.; Freathy, Rachel M; EGG Consortium.

    In: Nature Genetics, Vol. 51, No. 5, 2019, p. 804-814.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci. / Walford, Geoffrey A; Gustafsson, Stefan; Rybin, Denis; Stančáková, Alena; Chen, Han; Liu, Ching-Ti; Hong, Jaeyoung; Jensen, Richard A; Rice, Ken; Morris, Andrew P; Mägi, Reedik; Tönjes, Anke; Prokopenko, Inga; Kleber, Marcus E; Delgado, Graciela; Silbernagel, Günther; Jackson, Anne U; Appel, Emil V; Grarup, Niels; Lewis, Joshua P; Montasser, May E; Landenvall, Claes; Staiger, Harald; Luan, Jian'an; Frayling, Timothy M; Weedon, Michael N; Xie, Weijia; Morcillo, Sonsoles; Martínez-Larrad, María Teresa; Biggs, Mary L; Ida Chen, Yii-Der; Corbaton-Anchuelo, Arturo; Faerch, Kristine; Zumaquero, Juan Miguel; Goodarzi, Mark O; Kizer, Jorge; Koistinen, Heikki A; Leong, Aaron; Lind, Lars; Lindgren, Cecilia; Machicao, Fausto; Manning, Alisa K; Martín-Núñez, Gracia María; Rojo-Martínez, Gemma; Rotter, Jerome I; Siscovick, David S; Zmuda, Joseph M; Zhang, Zhongyang; Serrano-Rios, Manuel; Smith, Ulf; Soriguer, Federico; Hansen, Torben; Jørgensen, Torben; Linnenberg, Allan; Pedersen, Oluf; Walker, Mark; Langenberg, Claudia; Scott, Robert A; Wareham, Nicholas J; Fritsche, Andreas; Häring, Hans-Ulrich; Stefan, Norbert; Groop, Leif; O'Connell, Jeff R; Boehnke, Michael; Bergman, Richard N; Collins, Francis S; Mohlke, Karen L; Tuomilehto, Jaakko; März, Winfried; Kovacs, Peter; Stumvoll, Michael; Psaty, Bruce M; Kuusisto, Johanna; Laakso, Markku; Meigs, James B; Dupuis, Josée; Ingelsson, Erik; Florez, Jose C.

    In: Diabetes, Vol. 65, No. 10, 10.2016, p. 3200-3211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy). / Vorwerk, P; Christoffersen, C T; Müller, J; Vestergaard, H; Pedersen, O; De Meyts, P; Vestergaard, Henrik.

    In: Hormone Research, Vol. 52, No. 5, 1999, p. 211-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. / Voight, Benjamin F; Scott, Laura J; Steinthorsdottir, Valgerdur; Morris, Andrew P; Dina, Christian; Welch, Ryan P; Zeggini, Eleftheria; Huth, Cornelia; Aulchenko, Yurii S; Thorleifsson, Gudmar; McCulloch, Laura J; Ferreira, Teresa; Grallert, Harald; Amin, Najaf; Wu, Guanming; Willer, Cristen J; Raychaudhuri, Soumya; McCarroll, Steve A; Langenberg, Claudia; Hofmann, Oliver M; Dupuis, Josée; Qi, Lu; Segrè, Ayellet V; van Hoek, Mandy; Navarro, Pau; Ardlie, Kristin; Balkau, Beverley; Benediktsson, Rafn; Bennett, Amanda J; Blagieva, Roza; Boerwinkle, Eric; Bonnycastle, Lori L; Bengtsson Boström, Kristina; Bravenboer, Bert; Bumpstead, Suzannah; Burtt, Noisël P; Charpentier, Guillaume; Chines, Peter S; Cornelis, Marilyn; Couper, David J; Crawford, Gabe; Doney, Alex S F; Elliott, Katherine S; Elliott, Amanda L; Erdos, Michael R; Grarup, Niels; Jørgensen, Torben; Sparsø, Thomas; Hansen, Torben; Pedersen, Oluf; MAGIC investigators.

    In: Nature Genetics, Vol. 42, No. 7, 01.07.2010, p. 579-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota. / Vinberg, M.; Ottesen, N.; Meluken, I.; Sorensen, N.; Pedersen, O.; Kessing, L.; Miskowiak, K.

    In: European Neuropsychopharmacology, Vol. 29, No. Suppl. 1, 2019, p. S51.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    Remitted affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota. / Vinberg, M; Ottesen, N M; Meluken, I; Sørensen, N; Pedersen, O; Kessing, L V; Miskowiak, K W.

    In: Acta Psychiatrica Scandinavica, Vol. 139, No. 2, 2019, p. 174-184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals. / Vimaleswaran, Karani Santhanakrishnan; Luan, Jian'an; Andersen, Gitte; Muller, Y Li; Wheeler, Eleanor; Brito, Ema C; O'Rahilly, Stephen; Pedersen, Oluf; Baier, Leslie J; Knowler, William C; Barroso, Inês; Wareham, Nicholas J; Loos, Ruth J F; Franks, Paul W.

    In: Journal of Applied Physiology, Vol. 105, No. 4, 2008, p. 1352-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents. / Viitasalo, Anna; Schnurr, Theresia Maria; Pitkänen, Niina; Hollensted, Mette; Nielsen, Tenna R H; Pahkala, Katja; Lintu, Niina; Lind, Mads Vendelbo; Atalay, Mustafa; Frithioff-Bøjsøe, Christine; Fonvig, Cilius Esmann; Grarup, Niels; Kähönen, Mika; Larnkjær, Anni; Pedersen, Oluf Borbye; Holm, Jens-Christian; Michaelsen, Kim F.; Lakka, Timo A; Lehtimäki, Terho; Raitakari, Olli; Hansen, Torben; Kilpeläinen, Tuomas Oskari.

    In: International Journal of Obesity, Vol. 43, 2019, p. 2007-2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Abdominal adiposity and cardiometabolic risk factors in children and adolescents : A Mendelian randomization analysis. / Viitasalo, Anna; Schnurr, Theresia Maria; Pitkänen, Niina; Hollensted, Mette; Nielsen, Tenna R H; Pahkala, Katja; Atalay, Mustafa; Lind, Mads Vendelbo; Heikkinen, Sami; Frithioff-Bøjsøe, Christine; Fonvig, Cilius E; Grarup, Niels; Kähönen, Mika; Carrasquilla, Germán D; Larnkjær, Anni; Pedersen, Oluf; Michaelsen, Kim F.; Lakka, Timo A; Holm, Jens-Christian; Lehtimäki, Terho; Raitakari, Olli; Hansen, Torben; Kilpeläinen, Tuomas Oskari.

    In: American Journal of Clinical Nutrition, Vol. 110, No. 5, 2019, p. 1079-1087.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population. / Vestmar, Marie A; Galijatovic, Ehm Astrid Andersson; Christensen, Charlotte Riis; Pedersen, Maria Hauge; Glümer, Charlotte; Linneberg, Allan; Witte, Daniel R; Jørgensen, Marit E; Christensen, Cramer; Brandslund, Ivan; Lauritzen, Torsten ; Pedersen, Oluf; Holst, Birgitte; Grarup, Niels; Schwartz, Thue W; Hansen, Torben.

    In: Journal of Medical Genetics, Vol. 53, No. 9, 09.2016, p. 616-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid. / Vestergard, A.; Bredahl, K.; Muckadell, O.B. de; Pedersen, Oluf; Hansen, J.M.

    In: Ugeskrift for læger, Vol. 171, No. 4, 2009, p. 235-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy. / Vestergaard, H; Klein, H H; Hansen, T; Müller, J; Skovby, F; Bjørbaek, C; Røder, M E; Pedersen, O; Vestergaard, Henrik.

    In: The Journal of Clinical Investigation, Vol. 95, No. 4, 04.1995, p. 1925-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects : a longitudinal study. / Vestergaard, H; Weinreb, J E; Rosen, A S; Bjørbaek, C; Hansen, L; Pedersen, O; Kahn, B B.

    In: The Journal of clinical endocrinology and metabolism, Vol. 80, No. 1, 01.1995, p. 270-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Short- and long-term metabolic effects of recombinant human IGF-I treatment in patients with severe insulin resistance and diabetes mellitus. / Vestergaard, H; Rossen, M; Urhammer, S A; Müller, J; Pedersen, O.

    In: European Journal of Endocrinology, Vol. 136, No. 5, 05.1997, p. 475-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Unchanged gene expression of glycogen synthase in muscle from patients with NIDDM following sulphonylurea-induced improvement of glycaemic control. / Vestergaard, H; Lund, S; Bjørbaek, C; Pedersen, O.

    In: Diabetologia, Vol. 38, No. 10, 10.1995, p. 1230-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism. / Vestergaard, H; Lund, S; Pedersen, O; Vestergaard, Henrik.

    In: Journal of Internal Medicine, Vol. 250, No. 5, 11.2001, p. 406-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Expression of glycogen synthase and phosphofructokinase in muscle from type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment. / Vestergaard, H; Andersen, P H; Lund, S; Vedel, Peter; Pedersen, O.

    In: Diabetologia, Vol. 37, No. 1, 01.1994, p. 82-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Impaired expression of glycogen synthase mRNA in skeletal muscle of NIDDM patients. / Vestergaard, H; Bjørbaek, C; Andersen, P H; Bak, J F; Pedersen, O.

    In: Diabetes, Vol. 40, No. 12, 12.1991, p. 1740-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease. / Vazquez-Chantada, Mercedes; Gonzalez-Lahera, Aintzane; Martinez-Arranz, Ibon; Garcia-Monzon, Carmelo; Regueiro, Manuela M; Garcia-Rodriguez, Juan L; Schlangen, Karin A; Mendibil, Iñaki; Rodriguez-Ezpeleta, Naiara; Lozano, Juan J; Banasik, Karina; Justesen, Johanne M; Jørgensen, Torben; Witte, Daniel R; Lauritzen, Torsten; Hansen, Torben; Pedersen, Oluf; Veyrie, Nicolas; Clement, Karine; Tordjman, Joan; Tran, Albert; Le Marchand-Brustel, Yannik; Buque, Xabier; Aspichueta, Patricia; Echevarria-Uraga, Jose J; Martin-Duce, Antonio; Caballeria, Joan; Gual, Philippe; Castro, Azucena; Mato, Jose M; Martinez-Chantar, Maria L; Aransay, Ana M.

    In: Hepatology, Vol. 57, No. 2, 02.2013, p. 505-514.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes. / Van Zuydam, Natalie R.; Ahlqvist, Emma; Sandholm, Niina; Deshmukh, Harshal; William Rayner, N.; Abdalla, Moustafa; Ladenvall, Claes; Ziemek, Daniel; Fauman, Eric; Robertson, Neil R.; McKeigue, Paul M.; Valo, Erkka; Forsblom, Carol; Harjutsalo, Valma; Perna, Annalisa; Rurali, Erica; Loredana Marcovecchio, M.; Igo, Robert P.; Lajer, Maria; Ahluwalia, Tarunveer S.; Linneberg, Allan; Witte, Daniel R.; Grarup, Niels; Pedersen, Oluf; Hansen, Torben; Rossing, Peter; SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium.

    In: Diabetes, Vol. 67, No. 7, 2018, p. 1414-1427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published
  45. Published

    The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients. / Urhammer, Søren A.; Møller, Ann Merete; Nyholm, Birgit; Ekstrøm, Claus T.; Eiberg, Hans; Clausen, Jesper O.; Hansen, Torben; Pedersen, Oluf; Schmitz, Ole.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 83, No. 11, 20.11.1998, p. 3992-3995.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99). / Urdea, Mickey; Kolberg, Janice; Wilber, Judith; Gerwien, Robert; Moler, Edward; Rowe, Michael; Jorgensen, Paul; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben; Borch-Johnsen, Knut.

    In: Journal of Diabetes Science and Technology, Vol. 3, No. 4, 2009, p. 748-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. / Unoki, Hiroyuki; Takahashi, Atsushi; Kawaguchi, Takahisa; Hara, Kazuo; Horikoshi, Momoko; Andersen, Gitte; Ng, Daniel P K; Holmkvist, Johan; Borch-Johnsen, Knut; Jørgensen, Torben; Sandbæk, Annelli; Lauritzen, Torsten; Hansen, Torben; Nurbaya, Siti; Tsunoda, Tatsuhiko; Kubo, Michiaki; Babazono, Tetsuya; Hirose, Hiroshi; Hayashi, Matsuhiko; Iwamoto, Yasuhiko; Kashiwagi, Atsunori; Kaku, Kohei; Kawamori, Ryuzo; Tai, E Shyong; Pedersen, Oluf; Kamatani, Naoyuki; Kadowaki, Takashi; Kikkawa, Ryuichi; Nakamura, Yusuke; Maeda, Shiro.

    In: Nature Genetics, Vol. 40, No. 9, 2008, p. 1098-1102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. / Turcot, Valérie; Lu, Yingchang; Highland, Heather M; Bang, Lia E; Benn, Marianne; Kamstrup, Pia R; Bork-Jensen, Jette; Frikke-Schmidt, Ruth; Gjesing, Anette P; Grarup, Niels; Hansen, Torben; Have, Christian Theil; Jørgensen, Torben; Nielsen, Sune F.; Linneberg, Allan René; Pedersen, Oluf; Pers, Tune H; Vestergaard, Henrik; Nordestgaard, Børge; Tybjærg-Hansen, Anne; Varbo, Anette; CHD Exome+ Consortium; EPIC-CVD Consortium; ExomeBP Consortium; Global Lipids Genetics Consortium; GoT2D Genes Consortium; EPIC-InterAct Consortium; INTERVAL Study; ReproGen Consortium; T2D-Genes Consortium; The MAGIC Investigators; Understanding Society Scientific Group; Lindgren, Cecilia M; Hirschhorn, Joel N; Loos, Ruth J F.

    In: Nature Genetics, Vol. 50, 2018, p. 26-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Association of the calpain-10 gene with type 2 diabetes in Europeans : results of pooled and meta-analyses. / Tsuchiya, Takafumi; Schwarz, Peter E H; Bosque-Plata, Laura Del; Geoffrey Hayes, M; Dina, Christian; Froguel, Philippe; Wayne Towers, G; Fischer, Sabine; Temelkova-Kurktschiev, Theodora; Rietzsch, Hannes; Graessler, Juergen; Vcelák, Josef; Palyzová, Daniela; Selisko, Thomas; Bendlová, Bela; Schulze, Jan; Julius, Ulrich; Hanefeld, Markolf; Weedon, Michael N; Evans, Julie C; Frayling, Timothy M; Hattersley, Andrew T; Orho-Melander, Marju; Groop, Leif; Malecki, Maciej T; Hansen, Torben; Pedersen, Oluf; Fingerlin, Tasha E; Boehnke, Michael; Hanis, Craig L; Cox, Nancy J; Bell, Graeme I.

    In: Molecular Genetics and Metabolism, Vol. 89, No. 1-2, 2006, p. 174-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status. / Trier, Cæcilie; Dahl, Maria; Stjernholm, Theresa; Nielsen, Tenna Ruest Haarmark; Bøjsøe, Christine; Fonvig, Cilius Esmann; Pedersen, Oluf; Hansen, Torben; Holm, Jens-Christian.

    In: P L o S One, Vol. 11, No. 8, e0161921, 2016, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

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