Nicolai Jacob Wewer Albrechtsen

Nicolai Jacob Wewer Albrechtsen

Assistant professor

  • Translational Metabolic Physiology

  • Proteomics Program

    Blegdamsvej 3, 2200 København N, Bygning 6, Building: 06-6-28

    Phone: +45 35 33 04 85Mobile: +45 29 64 93 29

  1. 2019
  2. E-pub ahead of print

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice. / Jepsen, Sara L; Grunddal, Kaare V; Wewer Albrechtsen, Nicolai J; Engelstoft, Maja S; Gabe, Maria B N; Jensen, Elisa P; Ørskov, Cathrine; Poulsen, Steen S; Rosenkilde, Mette M; Pedersen, Jens; Gribble, Fiona M; Reimann, Frank; Deacon, Carolyn F; Schwartz, Thue W; Christ, Andreas D; Martin, Rainer E; Holst, Jens J.

    In: A J P: Endocrinology and Metabolism (Online), 10.09.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism. / Sakaguchi, Masaji; Cai, Weikang; Wang, Chih-Hao; Cederquist, Carly T; Damasio, Marcos; Homan, Erica P; Batista, Thiago; Ramirez, Alfred K; Gupta, Manoj K; Steger, Martin; Wewer Albrechtsen, Nicolai J; Singh, Shailendra Kumar; Araki, Eiichi; Mann, Matthias; Enerbäck, Sven; Kahn, C Ronald.

    In: Nature Communications, Vol. 10, No. 1, 05.04.2019, p. 1582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    The liver-alpha cell axis and type 2 diabetes. / Wewer Albrechtsen, Nicolai J; Pedersen, Jens; Galsgaard, Katrine D; Winther-Sørensen, Marie; Suppli, Malte P; Janah, Lina; Gromada, Jesper; Vilstrup, Hendrik; Knop, Filip K; Holst, Jens J.

    In: Endocrine Reviews, 28.03.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Glucose and Amino Acid Metabolism in Mice Depend Mutually on Glucagon and Insulin Receptor Signaling. / Galsgaard, Katrine D; Winther-Sørensen, Marie; Pedersen, Jens; Kjeldsen, Sasha A S; Rosenkilde, Mette M; Wewer Albrechtsen, Nicolai J; Holst, Jens J.

    In: A J P: Endocrinology and Metabolism (Online), 26.02.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents. / Christiansen, Charlotte Bayer; Trammell, Samuel Addison Jack; Albrechtsen, Nicolai Jacob Wewer; Schoonjans, Kristina; Albrechtsen, Reidar; Gillum, Matthew Paul; Kuhre, Rune Ehrenreich; Holst, Jens Juul.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 316, No. 5, 2019, p. G574-G584.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes : A Randomized Single-Blinded Placebo Controlled Study. / Behary, Preeshila; Tharakan, George; Alexiadou, Kleopatra; Johnson, Nicholas; Albrechtsen, Nicolai Jacob Wewer; Kenkre, Julia; Cuenco, Joyceline; Hope, David; Anyiam, Oluwaseun; Choudhury, Sirazum; Alessimii, Haya; Poddar, Ankur; Minnion, James; Doyle, Chedie; Frost, Gary; Le Roux, Carel; Purkayastha, Sanjay; Moorthy, Krishna; Dhillo, Waljit; Holst, Jens J; Ahmed, Ahmed R; Prevost, A Toby; Bloom, Stephen R; Tan, Tricia M.

    In: Diabetes Care, Vol. 42, No. 7, dc190449, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure : A Pilot Study. / Clarke, Sophie J.; Pettit, Stephen; Giblett, Joel P.; Zhao, Tian; Kydd, Anna C.; Albrechtsen, Nicolai J. W.; Deacon, Carolyn F.; Parameshwar, Jayan; Hoole, Stephen P.

    In: Clinical Therapeutics, Vol. 41, No. 1, 2019, p. 118-127.e0.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Glucagon Receptor Signaling and Glucagon Resistance. / Janah, Lina; Kjeldsen, Sasha; Galsgaard, Katrine D.; Winther-Sorensen, Marie; Stojanovska, Elena; Pedersen, Jens; Knop, Filip K.; Holst, Jens J.; Albrechtsen, Nicolai J. Wewer.

    In: International Journal of Molecular Sciences, Vol. 20, No. 13, 3314, 2019.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Glucagon Receptor Signaling and Lipid Metabolism. / Galsgaard, Katrine D; Pedersen, Jens; Knop, Filip K; Holst, Jens J; Wewer Albrechtsen, Nicolai J.

    In: Frontiers in Physiology, Vol. 10, 413, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Identification of ADAM12 as a Novel Basigin Sheddase. / Albrechtsen, Reidar; Wewer Albrechtsen, Nicolai J; Gnosa, Sebastian; Schwarz, Jeanette; Dyrskjøt, Lars; Kveiborg, Marie.

    In: International Journal of Molecular Sciences , Vol. 20, No. 8, 2019, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published
  13. Published

    No direct effect of SGLT2 activity on glucagon secretion. / Kuhre, Rune E; Ghiasi, Seyed M; Adriaenssens, Alice E.; Albrechtsen, Nicolai Jacob Wewer; Andersen, Daniel B.; Aivazidis, Alexander; Chen, Lihua; Mandrup-Poulsen, Thomas; Ørskov, Cathrine; Gribble, Fiona M.; Reimann, Frank; Wierup, Nils; Tyrberg, Björn; Holst, Jens J.

    In: Diabetologia, Vol. 62, No. 6, 2019, p. 1011-1023.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia. / Mulla, Christopher M.; Goldfine, Allison B.; Dreyfuss, Jonathan M.; Houten, Sander; Pan, Hui; Pober, David M.; Albrechtsen, Nicolai J. Wewer; Svane, Maria S.; Schmidt, Julie B.; Holst, Jens Juul; Craig, Colleen M.; McLaughlin, Tracey L.; Patti, Mary-Elizabeth.

    In: Obesity Surgery, Vol. 29, No. 7, 2019, p. 2092-2099.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease. / Niu, Lili; Geyer, Philipp E.; Albrechtsen, Nicolai Jacob Wewer; Gluud, Lise L; Santos, Alberto; Doll, Sophia; Treit, Peter V; Holst, Jens J; Knop, Filip K; Vilsbøll, Tina; Junker, Anders; Sachs, Stephan; Stemmer, Kerstin; Müller, Timo D; Tschöp, Matthias H; Hofmann, Susanna M; Mann, Matthias.

    In: Molecular Systems Biology, Vol. 15, e8793, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sacubitril/valsartan augments postprandial plasma concentrations of active GLP-1 when combined with sitagliptin in men. / Wewer Albrechtsen, Nicolai J; Mark, Peter D; Terzic, Dijana; Hansen, Lasse H; Andersen, Ulrik Ø; Hartmann, Bolette; Carr, Richard D; Gustafsson, Finn; Deacon, Carolyn F; Holst, Jens J; Goetze, Jens P; Plomgaard, Peter.

    In: The Journal of clinical endocrinology and metabolism, Vol. 104, No. 9, 2019, p. 3868-3876.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2018
  18. Published

    GLP-1 Is a Coronary Artery Vasodilator in Humans. / Clarke, Sophie J.; Giblett, Joel P.; Yang, Lucy L.; Hubsch, Annette; Zhao, Tian; Aetesam-ur-Rahman, Muhammad; West, Nick E. J.; O'Sullivan, Michael; Figg, Nichola; Bennett, Martin; Albrechtsen, Nicolai J. Wewer; Deacon, Carolyn F.; Cheriyan, Joseph; Hoole, Stephen P.

    In: Journal of the American Heart Association, Vol. 7, No. 22, e010321, 20.11.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    ADAM12-mediated shedding of basigin controls the subcellular localization and lactate transport of MCT4 and enhances collagen degradation in cancer cells : [Meeting Abstract}. / Albrechtsen, R.; Albrechtsen, N. J. Wewer; Kveiborg, M.

    In: International Journal of Experimental Pathology, Vol. 99, No. 6, 2018, p. A25-A25.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice. / Christiansen, Charlotte B.; Lind, Sara J.; Svendsen, Berit; Balk-Møller, Emilie; Dahlby, Tina; Kuhre, Rune E; Hartmann, Bolette; Mandrup-Poulsen, Thomas; Deacon, Carolyn F; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.

    In: Physiological Reports, Vol. 6, No. 13, e13788, 2018, p. 1-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Commentary : measurement of biomarkers in medicine. / Goetze, Jens P; Hansen, Lasse H; Terzic, Dijana; Mark, Peter D; Wewer Albrechtsen, Nicolai J; Plomgaard, Peter; Rehfeld, Jens F.

    In: Biomarkers in Medicine, Vol. 12, No. 9, 2018, p. 941-944.

    Research output: Contribution to journalComment/debateResearchpeer-review

  23. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis. / Galsgaard, Katrine D.; Winther-Sørensen, Marie; Ørskov, Cathrine; Kissow, Hannelouise; Poulsen, Steen S.; Vilstrup, Hendrik; Prehn, Cornelia; Adamski, Jerzy; Jepsen, Sara L.; Hartmann, Bolette; Hunt, Jenna; Charron, Maureen J; Pedersen, Jens; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 314, No. 1, 2018, p. E93-E103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Evidence of a liver-alpha cell axis in humans : hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids. / Wewer Albrechtsen, Nicolai J; Færch, Kristine; Jensen, Troels M; Witte, Daniel R; Pedersen, Jens; Mahendran, Yuvaraj; Jonsson, Anna E; Galsgaard, Katrine D; Winther-Sørensen, Marie; Torekov, Signe S; Lauritzen, Torsten; Pedersen, Oluf; Knop, Filip K; Hansen, Torben; Jørgensen, Marit E; Vistisen, Dorte; Holst, Jens J.

    In: Diabetologia, Vol. 61, No. 3, 2018, p. 671-680.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucagon receptor signaling in metabolic diseases. / Albrechtsen, Nicolai J. Wewer.

    In: Peptides, Vol. 100, 2018, p. 42-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes. / Wewer Albrechtsen, Nicolai J; Junker, Anders E; Christensen, Mette; Hædersdal, Sofie; Wibrand, Flemming; Lund, Allan M; Galsgaard, Katrine D; Holst, Jens J; Knop, Filip K; Vilsbøll, Tina.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 314, No. 1, 2018, p. G91-G96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published
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ID: 95638859