Matthias Mann

Matthias Mann

Research director, professor


  1. 2017
  2. Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function. / Hosp, Fabian; Gutiérrez-Ángel, Sara; Schaefer, Martin H; Cox, Jürgen; Meissner, Felix; Hipp, Mark S; Hartl, F-Ulrich; Klein, Rüdiger; Dudanova, Irina; Mann, Matthias.

    In: Cell Reports, Vol. 21, No. 8, 21.11.2017, p. 2291-2303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Region and cell-type resolved quantitative proteomic map of the human heart. / Doll, Sophia; Dreßen, Martina; Geyer, Philipp E; Itzhak, Daniel N; Braun, Christian; Doppler, Stefanie A; Meier, Florian; Deutsch, Marcus-Andre; Lahm, Harald; Lange, Rüdiger; Krane, Markus; Mann, Matthias.

    In: Nature Communications, Vol. 8, No. 1, 1469, 13.11.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. / Steger, Martin; Diez, Federico; Dhekne, Herschel S; Lis, Pawel; Nirujogi, Raja S; Karayel, Ozge; Tonelli, Francesca; Martinez, Terina N; Lorentzen, Esben; Pfeffer, Suzanne R; Alessi, Dario R; Mann, Matthias.

    In: eLife, Vol. 6, 10.11.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A Primer on Concepts and Applications of Proteomics in Neuroscience. / Hosp, Fabian; Mann, Matthias.

    In: Neuron, Vol. 96, No. 3, 01.11.2017, p. 558-571.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Why is it so difficult to measure glucagon-like peptide-1 in a mouse? / Windeløv, Johanne A; Wewer Albrechtsen, Nicolai J; Kuhre, Rune E; Jepsen, Sara L; Hornburg, Daniel; Pedersen, Jens; Jensen, Elisa P; Galsgaard, Katrine D; Winther-Sørensen, Marie; Ørgaard, Anne; Deacon, Carolyn F; Mann, Matthias; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens J.

    In: Diabetologia, Vol. 60, No. 10, 10.2017, p. 2066-2075.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Revisiting biomarker discovery by plasma proteomics. / Geyer, Philipp E; Holdt, Lesca M; Teupser, Daniel; Mann, Matthias.

    In: Molecular Systems Biology, Vol. 13, No. 9, 942, 26.09.2017.

    Research output: Contribution to journalReviewResearchpeer-review

  9. A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. / Tain, Luke S; Sehlke, Robert; Jain, Chirag; Chokkalingam, Manopriya; Nagaraj, Nagarjuna; Essers, Paul; Rassner, Mark; Grönke, Sebastian; Froelich, Jenny; Dieterich, Christoph; Mann, Matthias; Alic, Nazif; Beyer, Andreas; Partridge, Linda.

    In: Molecular Systems Biology, Vol. 13, No. 9, 15.09.2017, p. 939.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. / Kälin, Stefanie; Becker, Maike; Ott, Verena B; Serr, Isabelle; Hosp, Fabian; Mollah, Mohammad M H; Keipert, Susanne; Lamp, Daniel; Rohner-Jeanrenaud, Francoise; Flynn, Victoria K; Scherm, Martin G; Nascimento, Lucas F R; Gerlach, Katharina; Popp, Vanessa; Dietzen, Sarah; Bopp, Tobias; Krishnamurthy, Purna; Kaplan, Mark H; Serrano, Manuel; Woods, Stephen C; Tripal, Philipp; Palmisano, Ralf; Jastroch, Martin; Blüher, Matthias; Wolfrum, Christian; Weigmann, Benno; Ziegler, Anette-Gabriele; Mann, Matthias; Tschöp, Matthias H; Daniel, Carolin.

    In: Cell Metabolism, Vol. 26, No. 3, 05.09.2017, p. 475-492.e7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation. / Pünzeler, Sebastian; Link, Stephanie; Wagner, Gabriele; Keilhauer, Eva C; Kronbeck, Nina; Spitzer, Ramona Mm; Leidescher, Susanne; Markaki, Yolanda; Mentele, Edith; Regnard, Catherine; Schneider, Katrin; Takahashi, Daisuke; Kusakabe, Masayuki; Vardabasso, Chiara; Zink, Lisa M; Straub, Tobias; Bernstein, Emily; Harata, Masahiko; Leonhardt, Heinrich; Mann, Matthias; Rupp, Ralph Aw; Hake, Sandra B.

    In: E M B O Journal, Vol. 36, No. 15, 01.08.2017, p. 2263-2279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging. / Murgia, Marta; Toniolo, Luana; Nagaraj, Nagarjuna; Ciciliot, Stefano; Vindigni, Vincenzo; Schiaffino, Stefano; Reggiani, Carlo; Mann, Matthias.

    In: Cell Reports, Vol. 19, No. 11, 13.06.2017, p. 2396-2409.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements. / Zink, Lisa-Maria; Delbarre, Erwan; Eberl, H Christian; Keilhauer, Eva C; Bönisch, Clemens; Pünzeler, Sebastian; Bartkuhn, Marek; Collas, Philippe; Mann, Matthias; Hake, Sandra B.

    In: Nucleic Acids Research, Vol. 45, No. 10, 02.06.2017, p. 5691-5706.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Social network architecture of human immune cells unveiled by quantitative proteomics. / Rieckmann, Jan C; Geiger, Roger; Hornburg, Daniel; Wolf, Tobias; Kveler, Ksenya; Jarrossay, David; Sallusto, Federica; Shen-Orr, Shai S; Lanzavecchia, Antonio; Mann, Matthias; Meissner, Felix.

    In: Nature Immunology, Vol. 18, No. 5, 05.2017, p. 583-593.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics. / Kulak, Nils A; Geyer, Philipp E; Mann, Matthias.

    In: Molecular and Cellular Proteomics, Vol. 16, No. 4, 04.2017, p. 694-705.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Lysine acetylation in mitochondria : From inventory to function. / Hosp, Fabian; Lassowskat, Ines; Santoro, Valeria; De Vleesschauwer, David; Fliegner, Daniela; Redestig, Henning; Mann, Matthias; Christian, Sven; Hannah, Matthew A; Finkemeier, Iris.

    In: Mitochondrion, Vol. 33, 03.2017, p. 58-71.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Widespread Proteome Remodeling and Aggregation in Aging C. elegans. / Walther, Dirk M; Kasturi, Prasad; Zheng, Min; Pinkert, Stefan; Vecchi, Giulia; Ciryam, Prajwal; Morimoto, Richard I; Dobson, Christopher M; Vendruscolo, Michele; Mann, Matthias; Hartl, F Ulrich.

    In: Cell, Vol. 168, No. 5, 23.02.2017, p. 944.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Phylointeractomics reconstructs functional evolution of protein binding. / Kappei, Dennis; Scheibe, Marion; Paszkowski-Rogacz, Maciej; Bluhm, Alina; Gossmann, Toni Ingolf; Dietz, Sabrina; Dejung, Mario; Herlyn, Holger; Buchholz, Frank; Mann, Matthias; Butter, Falk.

    In: Nature Communications, Vol. 8, 08.02.2017, p. 14334.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination. / Dewar, James M; Low, Emily; Mann, Matthias; Räschle, Markus; Walter, Johannes C.

    In: Genes & Development, Vol. 31, No. 3, 01.02.2017, p. 275-290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology. / Robles, Maria S; Humphrey, Sean J; Mann, Matthias.

    In: Cell Metabolism, Vol. 25, No. 1, 10.01.2017, p. 118-127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Deep Proteome Profiling Reveals Common Prevalence of MZB1-positive Plasma B Cells in Human Lung and Skin Fibrosis. / Schiller, Herbert B; Mayr, Christoph H; Leuschner, Gabriela; Strunz, Maximilian; Staab-Weijnitz, Claudia; Preisendörfer, Stefan; Eckes, Beate; Moinzadeh, Pia; Krieg, Thomas; Schwartz, David A; Hatz, Rudolf A; Behr, Jürgen; Mann, Matthias; Eickelberg, Oliver.

    In: American Journal of Respiratory and Critical Care Medicine, Vol. 196, No. 10, 2017, p. 1298–1310.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis. / Hartl, Markus; Füßl, Magdalena; Boersema, Paul J.; Jost, Jan-Oliver; Kramer, Katharina; Bakirbas, Ahmet; Sindlinger, Julia; Plöchinger, Magdalena; Leister, Dario; Uhrig, Glen; Moorhead, Greg Bg; Cox, Jürgen; Salvucci, Michael E; Schwarzer, Dirk; Mann, Matthias; Finkemeier, Iris.

    In: Molecular Systems Biology, Vol. 13, No. 10, 949, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Plenary Lecture Proteomics technologies for signaling, clinical applications. / Mann, Matthias.

    2017. S62-S62.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

ID: 5650809