Ketil Mathiasen Viborg
Section for Plant Biochemistry
Thorvaldsensvej 40, 1871 Frederiksberg C
Plants produce a plethora of phytochemicals with potential applications as pharmaceuticals, colorants and flavors. Several of the biosynthetic pathways producing such phytochemicals are organized in dynamic enzyme complexes termed metabolons. As a part of my Ph.D i am investigating what facilitates the assembly of such metabolons, how the enzymes are orchestrated and how substrates are transferred between the biosynthetic enzymes. I am going to use state-of-the-art methods such as Cryo-EM and Native Mass Spectrometry trying to elucidate these metabolon structures with the goal of understanding the mechanisms, and use the gained knowledge to optimize heterologous production of valuable phytochemicals in industrial host systems.