Jørgen Erik Nielsen

Jørgen Erik Nielsen

Clinical Professor


  1. 2017
  2. Published

    Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation. / Ochalek, Anna; Mihalik, Balázs; Avci, Hasan X.; Chandrasekaran, Abinaya; Téglási, Annamária; Bock, István; Giudice, Maria Lo; Táncos, Zsuzsanna; Molnár, Kinga; László, Lajos; Nielsen, Jørgen E.; Holst, Bjørn; Freude, Kristine; Hyttel, Poul; Kobolák, Julianna; Dinnyés, András.

    In: Alzheimer's Research and Therapy, Vol. 9, No. 1, 90, 12.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3). / Rostgaard, Nina; Roos, Peter; Budtz-Jørgensen, Esben; Johannsen, Peter; Waldemar, Gunhild; Nørremølle, Anne; Lindquist, Suzanne G.; Gydesen, Susanne; Brown, Jeremy M.; Collinge, John; Isaacs, Adrian M.; Nielsen, Troels T.; Nielsen, Jørgen E; FReJA collaboration.

    In: Neurobiology of Aging, Vol. 59, 11.2017, p. 221.e1-221.e7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Evidence of oxidative stress and mitochondrial dysfunction in spinocerebellar ataxia type 2 (SCA2) patient fibroblasts : Effect of coenzyme Q10 supplementation on these parameters. / Cornelius, Nanna; Wardman, Jonathan H; Hargreaves, Iain P; Neergheen, Viruna; Bie, Anne Sigaard; Tümer, Zeynep; Nielsen, Jørgen E; Nielsen, Troels T.

    In: Mitochondrion, Vol. 34, 05.2017, p. 103-114.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Hereditary cerebral small vessel disease and stroke. / Søndergaard, Christian Baastrup; Nielsen, Jørgen Erik; Hansen, Christine Krarup; Christensen, Hanne.

    In: Clinical Neurology and Neurosurgery, Vol. 155, 04.2017, p. 45-57.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    A Novel TTBK2 De Novo Mutation in a Danish Family with Early-Onset Spinocerebellar Ataxia. / Lindquist, Suzanne Granhøj; Møller, Lisbeth Birk; Dali, Christine I.; Marner, Lisbeth; Kamsteeg, Erik Jan; Nielsen, Jørgen Erik; Hjermind, Lena Elisabeth.

    In: Cerebellum, Vol. 16, No. 1, 02.2017, p. 268-271.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    SCA28 : Novel Mutation in the AFG3L2 Proteolytic Domain Causes a Mild Cerebellar Syndrome with Selective Type-1 Muscle Fiber Atrophy. / Svenstrup, Kirsten; Nielsen, Troels Tolstrup; Aidt, Frederik; Rostgaard, Nina; Duno, Morten; Wibrand, Flemming; Vinther-Jensen, Tua; Law, Ian; Vissing, John; Roos, Peter; Hjermind, Lena Elisabeth; Nielsen, Jørgen Erik.

    In: The Cerebellum, Vol. 16, No. 1, 02.2017, p. 62-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published
  9. Published

    Defining active progressive multiple sclerosis. / Sellebjerg, Finn; Börnsen, Lars; Ammitzbøll, Cecilie; Nielsen, Jørgen Erik; Vinther-Jensen, Tua; Hjermind, Lena Elisabeth; von Essen, Marina; Ratzer, Rikke Lenhard; Soelberg Sørensen, Per; Romme Christensen, Jeppe.

    In: Multiple Sclerosis, Vol. 23, No. 13, 2017, p. 1727-1735.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation. / Clayton, Emma L.; Mancuso, Renzo; Nielsen, Troels Tolstrup; Mizielinska, Sarah; Holmes, Holly; Powell, Nicholas; Norona, Frances; Larsen, Jytte Overgaard; Milioto, Carmelo; Wilson, Katherine M.; Lythgoe, Mark F.; Ourselin, Sebastian; Nielsen, Jorgen E.; Johannsen, Peter; Holm, Ida; Collinge, John; Oliver, Peter L.; Gomez-Nicola, Diego; Isaacs, Adrian M.

    In: Human Molecular Genetics, Vol. 26, No. 5, 2017, p. 873-887.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B. / Zhang, Yu; Schmid, Benjamin; Nikolaisen, Nanett Kvist; Rasmussen, Mikkel A.; Garcia, Blanca Irene Aldana; Agger, Mikkel; Callø, Kirstine; Stummann, Tina C.; Larsen, Hjalte M. ; Nielsen, Troels T. ; Huang, Jinrong ; Xu, Fengping; Liu, Xin; Bolund, Lars; Meyer, Morten; Bak, Lasse Kristoffer; Waagepetersen, Helle S.; Luo, Yonglun; Nielsen, Jørgen Erik; Consortium, The FReJA ; Holst, Bjørn; Clausen, Christian; Hyttel, Poul; Freude, Kristine.

    In: Stem Cell Reports, Vol. 8, No. 3, 2017, p. 648-658.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 9689629