Jens Juul Holst

Jens Juul Holst

Professor


  1. 2017
  2. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Genetic determinants of circulating GIP and GLP-1 concentrations. / Almgren, Peter; Lindqvist, Andreas; Krus, Ulrika; Hakaste, Liisa; Ottosson-Laakso, Emilia; Asplund, Olof; Sonestedt, Emily; Prasad, Rashmi B; Laurila, Esa; Orho-Melander, Marju; Melander, Olle; Tuomi, Tiinamaija; Holst, Jens Juul; Nilsson, Peter M; Wierup, Nils; Groop, Leif; Ahlqvist, Emma.

    In: JCI insight, Vol. 2, No. 21, e93306, 02.11.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men. / Asmar, Ali; Asmar, Meena; Simonsen, Lene; Madsbad, Sten; Holst, Jens J; Hartmann, Bolette; Sorensen, Charlotte M; Bülow, Jens.

    In: Physiological Reports, Vol. 5, No. 3, e13073, 02.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor. / Asmar, Meena; Asmar, Ali; Simonsen, Lene; Gasbjerg, Lærke Smidt; Sparre-Ulrich, Alexander Hovard; Rosenkilde, Mette Marie; Hartmann, Bolette; Dela, Flemming; Holst, Jens Juul; Bülow, Jens.

    In: Diabetes, Vol. 66, No. 9, 09.2017, p. 2363-2371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Increased liver fat content in totally pancreatectomised patients. / Bagger, J. I.; Lund, A. B.; Albrechtsen, N. J. Wewer; Christensen, M.; Grøndahl, M. F.; Hansen, C. P.; Storkholm, J.; Holst, J. J.; Vilsboll, T.; Knop, F. K.

    In: Diabetologia, Vol. 60, No. S1, 2017, p. S572-S573.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  7. Published

    Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass. / Bojsen-Møller, Kirstine N; Dirksen, Carsten; Svane, Maria Saur; Jørgensen, Nils B; Holst, Jens Juul; Richter, Erik; Madsbad, Sten.

    In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 312, No. 5, 2017, p. R797-R805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells. / Booz, V.; Christiansen, C. B.; Kuhre, R. E.; Saltiel, M. Y.; Sturla, L.; Sociali, G.; Zocchi, E.; Holst, J. J.; Bruzzone, S.

    In: European Journal of Clinical Investigation, Vol. 47, 2017, p. 112-113.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Published

    Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes. / Bronden, A.; Alber, A.; Rohde, U.; Rehfeld, J. F.; Holst, J. J.; Vilsboll, T.; Knop, F. K.

    In: Diabetologia, Vol. 60, 2017, p. S113-S113.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  10. Published

    Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes. / Brønden, Andreas; Albér, Anders; Rohde, Ulrich; Rehfeld, Jens F; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K.

    In: The Journal of clinical endocrinology and metabolism, Vol. 102, No. 11, 11.2017, p. 4153-4162.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity. / Böhm, Anja; Wagner, Robert; Machicao, Fausto; Holst, Jens Juul; Gallwitz, Baptist; Stefan, Norbert; Fritsche, Andreas; Häring, Hans-Ulrich; Staiger, Harald.

    In: PloS one, Vol. 12, No. 7, e0181880, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men : a randomized crossover trial. / Canfora, Emanuel E; van der Beek, Christina M; Jocken, Johan W E; Goossens, Gijs H; Holst, Jens J; Olde Damink, Steven W M; Lenaerts, Kaatje; Dejong, Cornelis H C; Blaak, Ellen E.

    In: Scientific Reports, Vol. 7, 2360, 24.05.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals. / Canfora, Emanuel E; van der Beek, Christina M; Hermes, Gerben D A; Goossens, Gijs H; Jocken, Johan W E; Holst, Jens J; van Eijk, Hans M; Venema, Koen; Smidt, Hauke; Zoetendal, Erwin G; Dejong, Cornelis H C; Lenaerts, Kaatje; Blaak, Ellen E.

    In: Gastroenterology, Vol. 153, No. 1, 07.2017, p. 87-97.e3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Instrumentalization of eating improves weight loss maintenance in obesity. / Christensen, Bodil Just; Iepsen, Eva Pers Winning; Lundgren, Julie Rehné; Holm, Lotte; Madsbad, Sten; Holst, Jens Juul; Torekov, Signe Sørensen.

    In: Obesity Facts, Vol. 10, No. 6, 2017, p. 633-647.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia. / Craig, Colleen M; Liu, Li-Fen; Deacon, Carolyn F; Holst, Jens J; McLaughlin, Tracey L.

    In: Diabetologia, Vol. 60, No. 3, 03.2017, p. 531-540.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Discovery, characterization, and clinical development of the glucagon-like peptides. / Drucker, Daniel J; Habener, Joel F; Holst, Jens Juul.

    In: The Journal of Clinical Investigation, Vol. 127, No. 12, 01.12.2017, p. 4217-4227.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men. / Eelderink, Coby; Noort, Martijn W J; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J; Deacon, Carolyn F; Rehfeld, Jens F; Poutanen, Kaisa; Vonk, Roel J; Oudhuis, Lizette; Priebe, Marion G.

    In: European Journal of Nutrition, Vol. 56, No. 3, 2017, p. 1063-1076.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB. / Engelbrechtsen, Line; Lundgren, J; Wewer Albrechtsen, Nicolai Jacob; Mahendran, Yuvaraj ; Iepsen, Eva Pers Winning; Finocchietto, P.; Jonsson, Anna Elisabet ; Madsbad, Sten; Holst, Jens Juul; Vestergaard, Henrik; Hansen, T.; Torekov, Signe Sørensen.

    In: Obesity Science & Practice, Vol. 3, No. 4, 2017, p. 425-433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition. / Feng, Yongjia; Demehri, Farok R; Xiao, Weidong; Tsai, Yu-Hwai; Jones, Jennifer C; Brindley, Constance D; Threadgill, David W; Holst, Jens J; Hartmann, Bolette; Barrett, Terrence A; Teitelbaum, Daniel H; Dempsey, Peter J.

    In: Cellular and molecular gastroenterology and hepatology, Vol. 3, No. 3, 05.2017, p. 447-468.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference. / Foghsgaard, Signe; Andreasen, Camilla; Vedtofte, Louise; Andersen, Emilie S.; Bahne, Emilie; Strandberg, Charlotte; Buhl, Thora; Holst, Jens J; Svare, Jens A; Clausen, Tine D; Mathiesen, Elisabeth R; Damm, Peter; Gluud, Lise L; Knop, Filip K; Lauritsen, Tina Vilsbøll.

    In: Diabetes Care, Vol. 40, No. 1, 01.2017, p. 109-116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect. / Foghsgaard, Signe; Vedtofte, Louise; Andreasen, Camilla; Andersen, Emilie S; Bahne, Emilie; Bagger, Jonatan I; Svare, Jens A; Holst, Jens J; Clausen, Tine D; Mathiesen, Elisabeth R; Damm, Peter; Knop, Filip K; Vilsbøll, Tina.

    In: Diabetologia, Vol. 60, No. 7, 07.2017, p. 1344-1353.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia : a randomised, placebo-controlled, double-blind, parallel-group study. / Frandsen, Christian Seerup; Dejgaard, Thomas Fremming; Andersen, Henrik Ullits; Holst, Jens Juul; Hartmann, Bolette; Thorsteinsson, Birger; Madsbad, Sten.

    In: Diabetes, Obesity and Metabolism, Vol. 19, No. 6, 17.03.2017, p. 773-782.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Effect of oral contraceptives and/or metformin on GLP-1 secretion and reactive hypoglycaemia in polycystic ovary syndrome. / Glintborg, Dorte; Mumm, Hanne; Holst, Jens Juul; Andersen, Marianne.

    In: Endocrine Connections, Vol. 6, No. 4, 05.2017, p. 267-277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    TRPV1 : A Potential Therapeutic Target in Type 2 Diabetes and Comorbidities? / Gram, Dorte X; Holst, Jens J; Szallasi, Arpad.

    In: Trends in Molecular Medicine, Vol. 23, No. 11, 11.2017, p. 1002-1013.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Acute effects of glucagon-like peptide-1, GLP-19-36 amide, and exenatide on mesenteric blood flow, cardiovascular parameters, and biomarkers in healthy volunteers. / Hansen, Lasse Bremholm; Andersen, Ulrik B; Hornum, Mads; Hilsted, Linda; Veedfald, Simon; Hartmann, Bolette; Holst, Jens Juul.

    In: Physiological Reports, Vol. 5, No. 4, e13102, 02.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glucagon and Amino Acids Are Linked in a Mutual Feedback Cycle : The Liver-α-Cell Axis. / Holst, Jens J; Wewer Albrechtsen, Nicolai J; Pedersen, Jens; Knop, Filip K.

    In: Diabetes, Vol. 66, No. 2, 02.2017, p. 235-240.

    Research output: Contribution to journalJournal articleResearchpeer-review

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