Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects : a possible link between obesity and local tissue inflammation? / Arngrim, N; Simonsen, L; Holst, Jens Juul; Bülow, J.

    In: International Journal of Obesity, Vol. 37, 2012, p. 748-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model. / Barnes, Jennifer L; Hartmann, Bolette; Holst, Jens Juul; Tappenden, Kelly A.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 524-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Impact of postprandial glycaemia on health and prevention of disease. / Blaak, E E; Antoine, J-M; Benton, D; Björck, I; Bozzetto, L; Brouns, F; Diamant, M; Dye, L; Hulshof, T; Holst, J J; Lamport, D J; Laville, M; Lawton, C L; Meheust, A; Nilson, A; Normand, Signe; Rivellese, A A; Theis, S; Torekov, Signe Sørensen; Vinoy, S.

    In: Obesity Reviews, Vol. 13, No. 10, 2012, p. 923-984.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure. / Brinkman, Adam S; Murali, Sangita G; Hitt, Stacy; Solverson, Patrick M; Holst, Jens Juul; Ney, Denise M.

    In: A J P: Gastrointestinal and Liver Physiology (Online), Vol. 303, No. 5, 01.09.2012, p. G610-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery. / Bryant, Eleanor J; King, Neil A; Falkén, Ylva; Hellström, Per M; Holst, Jens Juul; Blundell, John E; Näslund, Erik.

    In: Surgery for Obesity and Related Diseases, 12.10.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Alcohol intake and its effect on some appetite-regulating hormones in man : influence of gastroprotection with sucralfate. / Calissendorff, Jan; Gustafsson, Thomas; Holst, Jens Juul; Brismar, Kerstin; Röjdmark, Sven.

    In: Endocrine Research, Vol. 37, No. 3, 2012, p. 154-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass. / Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Jacobsen, S H; Hansen, D L; Worm, D; Holst, Jens Juul; Madsbad, S.

    In: Diabetologia, Vol. 55, No. 7, 2012, p. 1890-901.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin. / Egerod, Kristoffer L; Engelstoft, Maja S; Grunddal, Kaare V; Nøhr, Mark K; Secher, Anna; Sakata, Ichiro; Pedersen, Jens; Windeløv, Johanne A; Füchtbauer, Ernst-Martin; Olsen, Jørgen; Sundler, Frank; Christensen, Jan P; Wierup, Nils; Olsen, Jesper V; Holst, Jens J; Zigman, Jeffrey M; Poulsen, Steen S; Schwartz, Thue W.

    In: Endocrinology, Vol. 153, No. 12, 01.12.2012, p. 5782-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection. / Ekholm, E; Shaat, N; Holst, Jens Juul.

    In: Acta Diabetologica, Vol. 49, No. 5, 10.2012, p. 349-54.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele. / Faerch, Kristine; Pilgaard, Kasper; Knop, Filip K; Hansen, Torben; Pedersen, Oluf; Jørgensen, Torben; Holst, Jens J.

    In: Diabetes, Obesity and Metabolism Online, Vol. 15, No. 1, 2012, p. 91-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Adult glucose metabolism in extremely birthweight-discordant monozygotic twins. / Frost, M; Petersen, I; Brixen, K; Beck-Nielsen, Henning; Holst, Jens Juul; Christiansen, L; Højlund, Kurt; Christensen, K.

    In: Diabetologia, Vol. 55, No. 12, 12.2012, p. 3204-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia. / Gejl, Michael; Egefjord, Lærke; Lerche, Susanne; Vang, Kim; Bibby, Bo Martin; Holst, Jens Juul; Mengel, Annette; Møller, Niels; Rungby, Jørgen; Brock, Birgitte; Gjedde, Albert.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 32, No. 12, 12.2012, p. 2146-2152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits. / Gjesing, Anette Marianne Prior; Ekstrøm, Claus Thorn; Eiberg, Hans Rudolf Lytchoff; Urhammer, S.A.; Holst, Jens Juul; Pedersen, Oluf; Hansen, Teis.

    In: Diabetologia, Vol. 55, No. 5, 2012, p. 1338-1345.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk. / Gunnerud, Ulrika; Holst, Jens Juul; Östman, Elin; Björck, Inger.

    In: Nutrition Journal, Vol. 11, 2012, p. 83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal. / Gunnerud, Ulrika J; Heinzle, Cornelia; Holst, Jens Juul; Östman, Elin M; Björck, Inger M E.

    In: P L o S One, Vol. 7, No. 9, 2012, p. e44731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    GPR119 as a fat sensor. / Hansen, Harald S; Rosenkilde, Mette M; Holst, Jens Juul; Schwartz, Thue W.

    In: Trends in Pharmacological Sciences, Vol. 33, No. 7, 07.2012, p. 374-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 4, 2012, p. 1363-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects. / Holmer-Jensen, Jens; Hartvigsen, Merete; Mortensen, L.S.; Astrup, Arne; de Vrese, M.; Holst, Jens Juul; Thomsen, C.; Hermansen, K.

    In: European Journal of Clinical Nutrition, Vol. 66, 2012, p. 32-38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Incretin based therapies : do they hold their promise? / Holst, Jens Juul.

    In: Journal of Diabetes, Vol. 4, No. 1, 2012, p. 4-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus : focus on bile acid sequestrants. / Holst, Jens Juul; McGill, Maria A.

    In: Clinical Drug Investigation, Vol. 32, No. 1, 2012, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Leptin og dens betydning for vægtvedligeholdelse. / Iepsen, Eva Pers Winning; Torekov, Signe Sørensen; Holst, Jens Juul.

    In: Klinisk biokemi i Norden, Vol. 24, No. 4, 2012, p. 8-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects. / Jacobsen, S H; Olesen, S C; Dirksen, C; Jørgensen, N B; Bojsen-Møller, K N; Kielgast, U; Worm, D; Almdal, T; Naver, L S; Hvolris, L E; Rehfeld, J F; Wulff, B S; Clausen, T R; Hansen, D L; Holst, Jens Juul; Madsbad, S.

    In: Obesity Surgery, Vol. 22, No. 7, 2012, p. 1084-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. / Jain, Ajay Kumar; Stoll, Barbara; Burrin, Douglas G; Holst, Jens Juul; Moore, David D.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 302, No. 2, 2012, p. G218-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes. / Jensen, D H; Aaboe, K; Henriksen, J E; Vølund, Anders; Holst, Jens Juul; Madsbad, S; Krarup, T.

    In: Diabetologia, Vol. 55, No. 5, 2012, p. 1406-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance. / Jørgensen, N B; Jacobsen, S H; Dirksen, C; Bojsen-Møller, K N; Naver, L; Hvolris, L; Clausen, T R; Wulff, B S; Worm, D; Lindqvist Hansen, D; Madsbad, S; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 303, No. 1, 2012, p. E122-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells. / Kappe, Camilla; Holst, Jens Juul; Zhang, Qimin; Sjöholm, Ake.

    In: Biochemical and Biophysical Research Communications, Vol. 427, No. 1, 12.10.2012, p. 91-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Poulsen, Steen Seier.

    In: Gut, 20.10.2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine. / Kissow, Hannelouise; Viby, Niels-Erik; Hartmann, Bolette; Holst, Jens Juul; Timm, Michael; Thim, Lars; Poulsen, Steen Seier.

    In: Cancer Chemotherapy and Pharmacology. Supplement, Vol. 70, No. 1, 2012, p. 39-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice. / Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul; Viby, Niels-Erik; Hansen, Lærke Schmidt; Rosenkilde, Mette Marie; Hare, Kristine Juul; Poulsen, Steen Seier.

    In: Regulatory Peptides, Vol. 179, No. 1-3, 10.11.2012, p. 91-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity. / Knop, Filip K; Aaboe, K; Vilsbøll, T; Vølund, Anders; Holst, Jens Juul; Krarup, T; Madsbad, S.

    In: Diabetes, Obesity and Metabolism, Vol. 14, No. 6, 2012, p. 500-510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome. / Lund, Pernille; Sangild, Per Torp; Aunsholt, L.; Hartmann, Bolette; Holst, Jens Juul; Mortensen, J.; Mortensen, P.B.; Jeppesen, P.B.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 9, 2012, p. 1059-1065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol. / Mandoe, M. J.; Hansen, K. B.; Knop, F. K.; Holst, J. J.; Hansen, Harald S.

    In: Diabetologia, Vol. 55, 10.2012, p. S340-S340.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Published

    Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy. / Mickiewicz, M; Zabielski, R; Grenier, B; Le Normand, L; Savary, G; Holst, Jens Juul; Oswald, I P; Metges, C C; Guilloteau, P.

    In: Journal of Physiology and Pharmacology, Vol. 63, No. 3, 2012, p. 225-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes. / Mortensen, L.S.; Holmer-Jensen, Jens; Hartvigsen, Merete; Jensen, V.K.; Astrup, Arne; Vrese, M. de; Holst, Jens Juul; Thomsen, Claus Heikki Paavo; Hermansen, Kjeld.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 7, 2012, p. 799-805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes. / Muscelli, Elza; Casolaro, Arturo; Gastaldelli, Amalia; Mari, Andrea; Seghieri, Giuseppe; Astiarraga, Brenno; Chen, Yu; Alba, Maria; Holst, Jens Juul; Ferrannini, Ele.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 8, 08.2012, p. 2818-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass : the pathophysiological role of GLP1 and its response to a somatostatin analogue. / Myint, K S; Greenfield, J R; Farooqi, I S; Henning, E; Holst, Jens Juul; Finer, N.

    In: European Journal of Endocrinology, Vol. 166, No. 5, 2012, p. 951-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink : a controlled trial. / Nielsen, Maria Mærsk; Sparre, Anita Belza; Holst, Jens Juul; Fenger-Grøn, Morten; Pedersen, S.B.; Astrup, Arne; Richelsen, Bjørn.

    In: European Journal of Clinical Nutrition, Vol. 66, No. 4, 2012, p. 523-529.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients. / Nielsen, R.; Wiggers, Henrik; Halbirk, Mads; Bøtker, H; Holst, Jens Juul; Schmitz, Ole; Frandsen, Egon Randa; Nielsen, S; Møller, N; Nørrelund, Helene.

    In: Experimental and Clinical Endocrinology and Diabetes, Vol. 120, No. 5, 2012, p. 266-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Treatment of adult short bowel syndrome patients with teduglutide. / Nørholk, Lærke Marijke; Holst, Jens Juul; Jeppesen, Palle Bekker.

    In: Expert Opinion on Pharmacotherapy, Vol. 13, No. 2, 2012, p. 235-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The incretin effect in patients with maturity onset diabetes of the young. / Ostoft, S. H.; Bagger, J. I.; Hansen, T.; Pedersen, O.; Holst, J. J.; Knop, F.; Vilsboll, T.

    In: Diabetologia, Vol. 55, 2012, p. S144-S144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes. / Rauch, T; Graefe-Mody, U; Deacon, Carolyn F.; Ring, A; Holst, Jens Juul; Woerle, H-J; Dugi, KA; Heise, T.

    In: Diabetes Therapy, Vol. 3, No. 1, 2012, p. 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus. / Rauch, Thomas; Graefe-Mody, Ulrike; Deacon, Carolyn F; Ring, Arne; Holst, Jens Juul; Woerle, Hans-Juergen; Dugi, Klaus A; Heise, Tim.

    In: Diabetes Therapy, Vol. 3, No. 1, 11.2012, p. 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals. / Rohrer, Stefan; Menge, Björn A; Grüber, Lena; Deacon, Carolyn F; Schmidt, Wolfgang E; Veldhuis, Johannes D; Holst, Jens Juul; Meier, Juris J.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 5, 2012, p. E791-E795.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells. / Salehi, Albert; Gunnerud, Ulrika; Muhammed, Sarheed J; Ostman, Elin; Holst, Jens Juul; Björck, Inger; Rorsman, Patrik.

    In: Nutrition & Metabolism, Vol. 9, No. 1, 2012, p. 48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans. / Schmidt, Julie Berg; Gunvald, Luise Enggaard; Gregersen, Nikolaj Ture; Pedersen, Susie Dawn; Holst, Jens Juul; Hansen, Dorte Lindqvist; Worm, Dorte; Madsbad, Sten; Astrup, Arne; Sjödin, Anders Mikael.

    In: Regulatory Peptides, Vol. 177, No. suppl.1, 2012, p. S32.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  46. Published

    Effects of intravenous infusions of PYY3-36 and GLP-1, as monoinfusion and in combination, on ad libitum energy intake in healthy obese subjects. / Schmidt, Julie Berg; Gregersen, Nikolaj Ture; Pedersen, Susie Dawn; Holst, Jens Juul; Schwartz, Thue W.; Astrup, Arne; Sjödin, Anders Mikael.

    In: Regulatory Peptides, Vol. 177, No. Supplement, 10.08.2012, p. S32.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes : collection of clinical data for glucose modeling. / Schmidt, Signe Damkjær; Finan, Daniel Aaron; Duun-Henriksen, Anne Katrine; Jørgensen, John Bagterp; Madsen, Henrik; Bengtsson, Henrik; Holst, Jens Juul; Madsbad, Sten; Nørgaard, Kirsten.

    In: Diabetes Technology & Therapeutics, Vol. 14, No. 3, 2012, p. 210-217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model. / Shang, Quan; Liu, Matthew K; Saumoy, Monica; Holst, Jens Juul; Salen, Gerald; Xu, Guorong.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 302, No. 8, 2012, p. G815-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The effect of glucagon-like peptide 1 on cardiovascular risk. / Sivertsen, Jacob; Rosenmeier, Jaya; Holst, Jens Juul; Vilsbøll, Tina.

    In: Nature Reviews Cardiology, Vol. 9, No. 4, 04.2012, p. 209-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Examining the effects of hyperglycemia on pancreatic endocrine function in humans : evidence for in vivo glucotoxicity. / Solomon, Thomas P J; Knudsen, Sine H; Karstoft, Kristian; Winding, Kamilla; Holst, Jens Juul; Pedersen, Bente K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 12, 12.2012, p. 4682-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

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