Jens Juul Holst

Jens Juul Holst

Professor


  1. 2011
  2. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. / Hansen, Katrine B; Rosenkilde, Mette M; Knop, Filip K; Wellner, Niels; Diep, Thi A; Rehfeld, Jens F; Andersen, Ulrik B; Holst, Jens J; Hansen, Harald S.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 9, 2011, p. E1409-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women. / Krog-Mikkelsen, Inger; Sloth, Birgitte; Dimitrov, Dimiter; Tetens, Inge; Björck, Inger; Flint, Anne; Holst, Jens Juul; Astrup, Arne; Elmstähl, Helena; Raben, Anne Birgitte.

    In: Journal of Nutrition, Vol. 141, No. 9, 2011, p. 1679-1684.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression. / Wang, Qian; Bailey, Charles G; Ng, Cynthia; Tiffen, Jessamy; Thoeng, Annora; Minhas, Vineet; Lehman, Melanie L; Hendy, Stephen C; Buchanan, Grant; Nelson, Colleen C; Rasko, John E J; Holst, Jeff; Holst, Jens Juul.

    In: Cancer Research, Vol. 71, No. 24, 2011, p. 7525-7536.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery : Role of Gut Peptides. / Falkén, Y; Hellström, P M; Holst, Jens Juul; Näslund, E.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 7, 2011, p. 2227-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin : a double-blinded randomized cross-over study. / Brock Jacobsen, I; Vind, B F; Korsholm, Lars; Flyvbjerg, A; Frystyk, Jan; Holst, Jens Juul; Beck-Nielsen, Henning; Henriksen, J E.

    In: Acta Physiologica (Print), Vol. 202, No. 3, 2011, p. 337-347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Delayed ß-cell response and glucose intolerance in young women with Turner syndrome. / Hjerrild, Britta Eilersen; Holst, Jens Juul; Juhl, Claus; Christiansen, Jens Sandahl; Schmitz, Ole; Gravholt, Claus Højbjerg.

    In: B M C Endocrine Disorders, Vol. 11, 2011, p. 11-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. / Hjøllund, K R; Deacon, C F; Holst, Jens Juul.

    In: Diabetologia, Vol. 54, No. 8, 2011, p. 2206-8.

    Research output: Contribution to journalLetterResearchpeer-review

  9. Published

    Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes. / Torekov, Signe Sørensen; Kipnes, M S; Harley, R E; Holst, J J; Ehlers, M R.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 7, 2011, p. 639-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes. / Henry, R R; Smith, Susanne; Schwartz, Saul; Mudaliar, S R; Deacon, C F; Holst, Jens Juul; Duan, R Y; Chen, R S; List, J F.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 9, 2011, p. 850-858.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction. / Lønborg, Jacob; Vejlstrup, Niels; Kelbæk, Henning; Bøtker, Hans Erik; Kim, Won Yong; Mathiasen, Anders B; Jørgensen, Erik; Helqvist, Steffen; Saunamäki, Kari; Clemmensen, Peter; Holmvang, Lene; Thuesen, Leif; Krusell, Lars Romer; Jensen, Jan S; Køber, Lars; Treiman, Marek; Holst, Jens Juul; Engstrøm, Thomas.

    In: European Heart Journal, Vol. 33, No. 12, 2011, p. 1491-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes. / Mentis, Nikolaos; Vardarli, Irfan; Köthe, Lars D; Holst, Jens Juul; Deacon, Carolyn F; Theodorakis, Michael; Meier, Juris J; Nauck, Michael A.

    In: Diabetes, Vol. 60, No. 4, 2011, p. 1270-1276.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Gastric bypass and duodenal and gastric feeding : a comment to Hansen et al. / Jorgensen, N B; Dirksen, C; Holst, Jens Juul; Madsbad, S.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 301, No. 5, 2011, p. G938-G9389.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gastric emptying of orally administered glucose solutions and incretin hormone responses are unaffected by laparoscopic adjustable gastric banding. / Usinger, Lotte; Hansen, Katrine B; Kristiansen, Viggo B; Larsen, Steen; Holst, Jens Juul; Knop, Filip K.

    In: Obesity Surgery, Vol. 21, No. 5, 2011, p. 625-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes. / Ketterer, Caroline; Müssig, Karsten; Heni, Martin; Dudziak, Katarzyna; Randrianarisoa, Elko; Wagner, Robert; Machicao, Fausto; Stefan, Norbert; Holst, Jens Juul; Fritsche, Andreas; Häring, Hans-Ulrich; Staiger, Harald.

    In: Metabolism, Vol. 60, No. 9, 2011, p. 1325-1333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glucagon like-peptide 1 receptor and the liver. / Pedersen, Jens; Holst, Jens Juul.

    In: Liver international : official journal of the International Association for the Study of the Liver, Vol. 31, No. 9, 2011, p. 1243-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Glucagon-like peptide 2 (Glp-2) stimulates intestinal function during weaning. / Thymann, Thomas; Huërou-Luron, I. Le; Petersen, Y.M.; Hedemann, Mette Skou; Elnif, Jan; Jensen, B.B.; Hartmann, Bolette; Holst, Jens Juul; Sangild, Per Torp.

    44th annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, 2011: programme and abstract booklet. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), 2011. p. 202.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  18. Published

    Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves. / Taylor-Edwards, C C; Burrin, D G; Holst, Jens Juul; McLeod, K R; Harmon, D L.

    In: Journal of Dairy Science, Vol. 94, No. 2, 2011, p. 888-898.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucose-dependent insulinotropic polypeptide : a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans. / Christensen, Mikkel; Vedtofte, Louise; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K.

    In: Diabetes, Vol. 60, No. 12, 2011, p. 3103-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1. / Torekov, S S; Ma, L; Grarup, N; Hartmann, B; Hainerová, I A; Kielgast, U; Kissow, H; Rosenkilde, M; Lebl, J; Witte, D R; Jørgensen, T; Sandbaek, A; Lauritzen, T; Madsen, O D; Wang, J; Linneberg, A; Madsbad, S; Holst, J J; Hansen, T; Pedersen, O; GIANT Consortium.

    In: Diabetologia, Vol. 54, No. 11, 2011, p. 2820-31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes. / Bagger, Jonatan I; Knop, Filip K; Lund, Asger; Vestergaard, Henrik; Holst, Jens Juul; Vilsbøll, Tina.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 3, 2011, p. 737-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 2, 2011, p. 447-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet : a randomised controlled trial. / Raben, Anne Birgitte; Møller, Bente Kramer; Flint, Anne; Vasilaris, Tatjana H.; Møller, A. Christina; Holst, Jens Juul; Astrup, Arne.

    In: Food & Nutrition Research, Vol. 55, No. 5961, 2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes. / Vardarli, Irfan; Nauck, Michael A; Köthe, Lars D; Deacon, Carolyn F; Holst, Jens Juul; Schweizer, Anja; Foley, James E.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 4, 2011, p. 945-954.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Inkretiner. / Vilsbøll, Tina; Holst, Jens Juul.

    Diabetes - sygdom, behandling og organisation. ed. / Jannik Hilsted; Knut Borch-Johnsen; Jens Sandahl Christiansen. 2. ed. København : Munksgaard , 2011. p. 67-74.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  26. Published

    Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion. / Witte, Anne-Barbara; Grybäck, Per; Jacobsson, Hans; Näslund, Erik; Hellström, Per Martin; Holst, Jens Juul; Hilsted, Linda; Schmidt, Peter Thelin.

    In: Scandinavian Journal of Gastroenterology. Supplement, Vol. 46, No. 4, 2011, p. 428-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events : Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials. / Buse, John B; Garber, Alan; Rosenstock, Julio; Schmidt, Wolfgang E; Brett, Jason H; Videbæk, Nicoline; Holst, Jens Juul; Nauck, Michael.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 6, 2011, p. 1695-702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Lixisenatide for type 2 diabetes mellitus. / Christensen, Mikkel; Knop, Filip K; Vilsbøll, Tina; Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 20, No. 4, 2011, p. 549-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test. / Møller, Jonas B; Jusko, William J; Gao, Wei; Hansen, Torben; Pedersen, Oluf; Holst, Jens J; Overgaard, Rune Viig; Madsen, Henrik; Ingwersen, Steen H.

    In: Journal of Pharmacokinetics and Pharmacodynamics, Vol. 38, No. 6, 2011, p. 713-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Neuroprotective properties of GLP-1 : theoretical and practical applications. / Holst, Jens Juul; Burcelin, Remy; Nathanson, Esther.

    In: Current Medical Research and Opinion, Vol. 27, No. 3, 2011, p. 547-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential. / Torekov, S S; Madsbad, S; Holst, Jens Juul.

    In: Obesity Reviews, Vol. 12, No. 8, 2011, p. 593-601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Protein dose-response effect on glp-1, pyy and appetite in male subjects. / Sparre, Anita Belza; Sørensen, Mejse Quistorff; Holst, Jens Juul; Rehfeld, Jens Frederik; Astrup, Arne.

    In: Obesity Reviews, Vol. 12, No. suppl. 1, 2011, p. 59.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Published

    Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans. / Nauck, Michael A; Kemmeries, Guido; Holst, Jens Juul; Meier, Juris J.

    In: Diabetes, Vol. 60, No. 5, 2011, p. 1561-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes : what is up, what is down? / Nauck, M A; Vardarli, I; Deacon, C F; Holst, Jens Juul; Meier, Joachim.

    In: Diabetologia, Vol. 54, No. 1, 2011, p. 10-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients. / Bremholm, Lasse; Hornum, Mads; Andersen, Ulrik B; Hartmann, Bolette; Holst, Jens Juul; Jeppesen, Palle Bekker.

    In: Regulatory Peptides, Vol. 168, No. 1-3, 2011, p. 32-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys. / Pedersen, Maiken Højgaard; Mølgaard, Christian; Hellgren, Lars; Matthiessen, Jeppe; Holst, Jens Juul; Lauritzen, Lotte.

    In: Journal of Nutrition and Metabolism, Vol. 2011, No. 348368, 2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The effects of L-arabinose on intestinal sucrase activity : dose-response studies in vitro and in humans. / Krog-Mikkelsen, Inger; Hels, Ole; Tetens, Inge; Holst, Jens Juul; Andersen, Jens Rikardt; Bukhave, Klaus.

    In: American Journal of Clinical Nutrition, Vol. 94, No. 2, 2011, p. 472-478.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes. / Lund, Asger; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 300, No. 6, 2011, p. E1038-E1046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia? / Hansen, A M K; Bödvarsdottir, T B; Nordestgaard, D N E; Heller, R S; Gotfredsen, C F; Maedler, K; Fels, JJ; Holst, Jens Juul; Karlsen, AE.

    In: Diabetologia, Vol. 54, No. 6, 2011, p. 1379-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal. / Naessén, Sabine; Carlström, Kjell; Holst, Jens Juul; Hellström, Per M; Hirschberg, Angelica L.

    In: American Journal of Clinical Nutrition, Vol. 94, No. 4, 2011, p. 967-972.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published
  42. Published

    The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status. / Gjesing, Anette P; Vestmar, Marie A; Jørgensen, Torben; Heni, Martin; Holst, Jens J; Witte, Daniel R; Hansen, Torben; Pedersen, Oluf.

    In: P L o S One, Vol. 6, No. 9, 01.01.2011, p. e23907.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men. / Nathanson, D; Zethelius, B; Berne, C; Lind, L; Andrén, B; Ingelsson, E; Holst, Jens Juul; Nyström, T.

    In: Diabetic Medicine, Vol. 28, No. 3, 03.2011, p. 301-305.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats. / Thomsen, Karen; Aagaard, Niels Kristian; Grønbæk, Henning; Holst, Jens Juul; Jessen, Niels; Frystyk, Jan; Vilstrup, Hendrik.

    In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 71, No. 2, 04.2011, p. 150-156.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4. / Hansen, Morten; Knop, Filip Krag; Holst, Jens Juul.

    In: Medecine des Maladies Metaboliques, Vol. 5, No. 2, 04.2011.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future. / Madsbad, S; Kielgast, U; Asmar, M; Deacon, C F; Torekov, Signe Sørensen; Holst, J J.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 5, 05.2011, p. 394-407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function. / Kielgast, Urd; Holst, Jens Juul; Madsbad, Sten.

    In: Diabetes, Vol. 60, No. 5, 05.2011, p. 1599-1607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes. / Holst, Jens Juul; Knop, Filip K; Vilsbøll, Tina; Krarup, Thure; Madsbad, Sten.

    In: Diabetes Care, Vol. 34, No. Supplement 2, 05.2011, p. S251-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors. / Hansen, Morten; Juul Hare, Kristine; Holst, Jens Juul; Knop, Filip Krag.

    In: Journal of Clinical Metabolism & Diabetes, Vol. 2, No. 2, 06.2011, p. 7-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    KU bestemmer selv over sin forskning. / Wewer, Ulla M.; Holst, Jens Juul; Schwartz, Thue W.; Quistorff, Bjørn.

    In: Universitetsavisen, 02.06.2011.

    Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

  51. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects. / Lindgren, O; Carr, RD; Holst, Jens Juul; Deacon, Carolyn F.; Ahren, B.

    In: Diabetes, Obesity and Metabolism Online, Vol. 13, No. 9, 07.2011, p. 863-865.

    Research output: Contribution to journalJournal articleResearchpeer-review

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