Jens Juul Holst

Jens Juul Holst

Professor


  1. 2003
  2. Published

    Role of gastrointestinal hormones in postprandial reduction of bone resorption. / Henriksen, Dennis B; Alexandersen, Peter; Bjarnason, Nina H; Vilsbøll, Tina; Hartmann, Bolette; Henriksen, Eva E G; Byrjalsen, Inger; Krarup, Thure; Holst, Jens Juul; Christiansen, Claus.

    In: J Bone Miner Res, Vol. 18, No. 12, 01.12.2003, p. 2180-2190.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety. / Schmidt, P T; Näslund, E; Grybäck, P; Jacobsson, H; Hartmann, B; Holst, Jens Juul; Hellström, P M.

    In: Regulatory Peptides, Vol. 116, No. 1-3, 15.11.2003, p. 21-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. / Jackson, Robert S; Creemers, John W M; Farooqi, I Sadaf; Raffin-Sanson, Marie-Laure; Varro, Andrea; Dockray, Graham J; Holst, Jens Juul; Brubaker, Patricia L; Corvol, Pierre; Polonsky, Kenneth S; Ostrega, Diane; Becker, Kenneth L; Bertagna, Xavier; Hutton, John C; White, Anne; Dattani, Mehul T; Hussain, Khalid; Middleton, Stephen J; Nicole, Thomasina M; Milla, Peter J; Lindley, Keith J; O'Rahilly, Stephen.

    In: The Journal of Clinical Investigation, Vol. 112, No. 10, 11.2003, p. 1550-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread. / Juntunen, Katri S; Laaksonen, David E; Autio, Karin; Niskanen, Leo K; Holst, Jens Juul; Savolainen, Kari E; Liukkonen, Kirsi-Helena; Poutanen, Kaisa S; Mykkänen, Hannu M.

    In: Uden navn, Vol. 78, No. 5, 11.2003, p. 957-64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans. / Ahrén, Bo; Holst, Jens Juul; Mari, Andrea.

    In: Diabetes Care. Supplement, Vol. 26, No. 10, 10.2003, p. 2860-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1 (GLP-1) in healthy volunteers. / Meier, S; Hücking, K; Ritzel, R; Holst, Jens Juul; Schmiegel, W H; Nauck, M A.

    In: Hormone and Metabolic Research. Supplement, Vol. 35, No. 9, 09.2003, p. 551-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum. / Schmidt, P T; Orskov, C; Rasmussen, T N; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, Vol. 38, No. 9, 09.2003, p. 955-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects. / Vilsbøll, Tina; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul.

    In: Regulatory Peptides, Vol. 114, No. 2-3, 15.07.2003, p. 115-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1. / Guan, Xinfu; Stoll, Barbara; Lu, Xiaofeng; Tappenden, Kelly A; Holst, Jens Juul; Hartmann, Bolette; Burrin, Douglas G.

    In: Gastroenterology, Vol. 125, No. 1, 07.2003, p. 136-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia. / Meier, J J; Gallwitz, B; Siepmann, N; Holst, Jens Juul; Deacon, C F; Schmidt, W E; Nauck, M A.

    In: Diabetologia, Vol. 46, No. 6, 06.2003, p. 798-801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus. / Vilsbøll, T; Krarup, T; Sonne, J; Madsbad, S; Vølund, A; Juul, A G; Holst, Jens Juul.

    In: The Journal of clinical endocrinology and metabolism, Vol. 88, No. 6, 06.2003, p. 2706-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men. / Jensen, Christine B; Storgaard, Heidi; Holst, Jens Juul; Dela, Flemming; Madsbad, Sten; Vaag, Allan A.

    In: The Journal of clinical endocrinology and metabolism, Vol. 88, No. 6, 06.2003, p. 2775-83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development. / Petersen, Yvette M; Hartmann, Bolette; Holst, Jens Juul; Le Huerou-Luron, Isabelle; Bjørnvad, Charlotte R; Sangild, Per T.

    In: Journal of Nutrition, Vol. 133, No. 6, 06.2003, p. 1781-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes. / Meier, Juris J; Gallwitz, Baptist; Salmen, Stefan; Goetze, Oliver; Holst, Jens Juul; Schmidt, Wolfgang E; Nauck, Michael A.

    In: The Journal of clinical endocrinology and metabolism, Vol. 88, No. 6, 06.2003, p. 2719-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects. / Sørensen, L B; Flint, A; Raben, A; Hartmann, B; Holst, Jens Juul; Astrup, A.

    In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, Vol. 27, No. 4, 04.2003, p. 450-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection. / Dahly, Elizabeth M; Gillingham, Melanie B; Guo, Ziwen; Murali, Sangita G; Nelson, David W; Holst, Jens Juul; Ney, Denise M.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 284, No. 4, 04.2003, p. G670-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit. / Larsen, P J; Seier, V; Fink-Jensen, A; Holst, Jens Juul; Warberg, J; Vrang, N.

    In: Journal of Neuroendocrinology, Vol. 15, No. 3, 03.2003, p. 219-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes. / Thomsen, Claus; Storm, Hanne; Holst, Jens Juul; Hermansen, Kjeld.

    In: Uden navn, Vol. 77, No. 3, 03.2003, p. 605-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion : effects on beta-cell sensitivity in type 2 and nondiabetic subjects. / Kjems, Lise L; Holst, Jens Juul; Vølund, Aage; Madsbad, Sten.

    In: Diabetes, Vol. 52, No. 2, 02.2003, p. 380-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects. / Vilsbøll, T; Agersø, H; Krarup, T; Holst, Jens Juul.

    In: The Journal of clinical endocrinology and metabolism, Vol. 88, No. 1, 01.2003, p. 220-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1(GLP-1) in healthy volunteers. / Meier, S.; Hücking, K.; Ritzelt, R.; Holst, Jens Juul; Schmiegel, W.H.; Nauck, M.A.

    In: Horm Metab Res, No. 35, 2003, p. 551-556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Characterization of GLP-1 effects on beta cell function after meal ingestion in humans. / Ahren, B.; Holst, Jens Juul; Mari, A.

    In: Diabetes Care, No. 26, 2003, p. 2860-2864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Circulating leptin and thyroid dysfunction. / Zimmermann-Belsing, Tina; Brabant, Georg; Holst, Jens Juul; Feldt-Rasmussen, Ulla.

    In: European Journal of Endocrinology, Vol. 149, No. 4, 2003, p. 257-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Cocaine and amphetamine-regulated transcript (CART) is present in hypothalamic neuroendocrine neurons and is related to the hypothalamo-pituitary portal circuit. / Larsen, P.J.; Seier, V.; Fink-Jensen, A.; Holst, Jens Juul; Warberg, Jørgen; Vrang, N.

    In: Journal of Neuroendocrinology, No. 15, 2003, p. 219-226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease. / Piche, Thierry; des Varannes, Stanislas Bruley; Sacher-Huvelin, Sylvie; Holst, Jens Juul; Cuber, Jean Claude; Galmiche, Jean Paul.

    In: Gastroenterology, Vol. 124, No. 4, 2003, p. 894-902.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals. / Mersebach, H.; Svendsen, Ole Lander; Holst, Jens Juul; Astrup, Arne; Feldt-Rasmussen, Ulla.

    In: Clinical Endocrinology, Vol. 58, No. 1, 2003, p. 65-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Differential effects of saturated and monounsaturated fat on postprandial lipemia and incretin responses in type 2 diabetic subjects. / Thomsen, C.; Storm, H.; Holst, Jens Juul; Hermansen, K.

    In: Am. J. Clin. Nutr., No. 77, 2003, p. 605-611.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Differential regional metabolism of glucagon in anesthetized pigs. / Deacon, Carolyn F; Kelstrup, Mette; Trebbien, Ramona; Klarskov, Letty; Olesen, Mette; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 285, No. 3, 2003, p. E552-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes. / Staehr, P.; Højlund, K.; Hother-Nielsen, O.; Holst, Jens Juul; Beck-Nielsen, H.

    In: Diabetic Medicine, No. 20, 2003, p. 816-822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea. / Nielsen, T.T.; Sangild, P.T.; Elnif, J.; Sorensen, K.; Leser, T.; Holst, Jens Juul; Hartmann, B.; Jensen, B.B.; Hedemann, M.S.

    Ikke angivet. ed. / R.O. Ball. 2. ed. University of Alberta Press, 2003. p. 161-163.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  32. Published

    Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis. / Staehr, Peter; Hother-Nielsen, Ole; Landau, Bernard R; Chandramouli, Visvanathan; Holst, Jens Juul; Beck-Nielsen, Henning.

    In: Diabetes, Vol. 52, No. 2, 2003, p. 260-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Et æble om dagen. / Larsen, P. J.; Holst, Jens Juul; Astrup, A.

    In: Politiken, Vol. 29, 2003.

    Research output: Contribution to journalContribution to newspaper - Feature articleCommunication

  34. Published

    Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets. / le Huërou-Luron, I.; Petersen, Y.M.; Hartmann, B.; Holst, Jens Juul; Sangild, P.T.

    Ikke angivet. ed. / R.O. Ball. 2. ed. University of Alberta Press, 2003. p. 164-166.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  35. Published

    Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters. / Nielsen, T B; Yderstraede, K B; Schrøder, H D; Holst, Jens Juul; Brusgaard, Klaus; Beck-Nielsen, H.

    In: Cell Transplantation, Vol. 12, No. 1, 2003, p. 13-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. / Mortensen, Kristine; Christensen, Louise Lundby; Holst, Jens Juul; Ørskov, Cathrine.

    In: Regulatory Peptides, Vol. 114, No. 2-3, 2003, p. 189-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets. / Guan, X.; Stoll, B.; Lu, X.; Tappenden, K.; Holst, Jens Juul; Hartmann, Bolette; Burrin, D.G.

    In: Today in Medicine. Gastroenterology, No. 125, 2003, p. 136-147.

    Research output: Contribution to journalJournal articleResearch

  38. Published

    Gastric inhibitory polypeptide (GIP) does not inhibit gastric emptying in man. / Meier, J.M.; Goetze, O.; Anstipp, J.; Hagemann, D.; Holst, J.J.; Schmidt, W.E.; Gallwitz, B.; Nauck, M.A.

    In: Am. J. Physiol., No. 16, 2003, p. E621-E625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia. / Meier, J.J.; Gallwitz, N.; Siepmann, N.; Holst, Jens Juul; Deacon, C.F.; Schmidt, W.E.; Nauck, M.A.

    In: Diabetologia, No. 46, 2003, p. 798-801.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1. / Ugleholdt, Randi; Zhu, Xiaorong; Deacon, Carolyn F; Ørskov, Cathrine; Steiner, Donald F; Holst, Jens J.

    In: Endocrinology, Vol. 145, No. 3, 2003, p. 1349-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors. / Holst, Jens Juul.

    In: Advances in Experimental Medicine and Biology, Vol. 524, 2003, p. 263-79.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and in people with type 1 and type 2 diabetes mellitus. / Vilsbøll, T.; Krarup, T.; Sonne, J.; Madsbad, S.; Vølund, A.; Juul, A.G.; Holst, Jens Juul.

    In: J. Clin. Endocrinol. Metab., No. 88, 2003, p. 2706-2713.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men. / Jensen, Christine B; Storgaard, Heidi; Holst, Jens Juul; Dela, Flemming; Madsbad, Sten; Vaag, Allan A.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 88, No. 6, 2003, p. 2775-2783.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development. / Petersen, Y. M.; Hartmann, B.; Holst, Jens Juul; Le Huërou-Luron, I.; Bjørnvad, C. R.; Sangild, P. T.

    In: Journal of Nutrition, Vol. 133, No. 6, 2003, p. 1781-1786.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Lower blood glucose, hyperglucagonemia and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. / Gelling, R.W.; Du, X.Q.; Dichmann, D.S.; Rømer, J.; Huan, H.; Cui, L.; Tang, B.L.; Holst, Jens Juul; Fledelius, C.; Johansen, P.B.; Jelicks, L.A.; Serup, P.; Nishimura, E.; Charron, M.J.

    In: Proc Natl Sci, No. 100, 2003, p. 1438-1443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing. / Bakhøj, S; Flint, A.; Holst, Jens Juul; Tetens, Inge.

    In: European Journal of Clinical Nutrition, Vol. 57, No. 10, 2003, p. 1254-1261.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake. / Raben, A. B.; Agerholm-Larsen, L.; Flint, Anne; Holst, Jens Juul; Astrup, A.

    In: American Journal of Clinical Nutrition, Vol. 77, No. 1, 2003, p. 91-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    NO has tonic inhibitory, but is not involved in the vagal control or VIP effects on motility of the porcine antrum. / Schmidt, P.T.; Ørskov, C.; Rasmussen, T.N.; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, No. 38, 2003, p. 955-961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo. / Plamboeck, Astrid; Holst, Jens J; Carr, Richard D; Deacon, Carolyn F.

    In: Advances in Experimental Medicine and Biology, Vol. 524, 2003, p. 303-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects. / Sørensen, L. B.; Flint, A.; Raben, A. B.; Hartmann, B.; Holst, Jens Juul; Astrup, A.

    In: International Journal of Obesity, Vol. 27, No. 4, 2003, p. 450-456.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    No reactive hypoglycaemia after subcutaneous administrations of GLP-1 in lean type 2 diabetic patients and in patients with diabeties secondary to chronic pancreatitis. / Knop, F.; Vilsbøll, T.; Larsen, S.; Holst, Jens Juul; Krarup, T.

    In: Diabetes Care, No. 26, 2003, p. 2581-2587.

    Research output: Contribution to journalJournal articleResearchpeer-review

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