Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs. / Barkholt, Pernille; Vegge, Andreas; Clausen, Trine Ryberg; Birck, Malene Muusfeldt; Fels, Johannes Josef; Støckel, Mikael; Gögenür, Ismayil; Eriksen, Thomas; Holst, Jens Juul; Hansen, Axel Kornerup; Thymann, Thomas; Jelsing, Jacob; Sangild, Per Torp; Raun, Kirsten.

    In: Journal of Obesity and Bariatrics, Vol. 1, No. 1, 2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    In vivo efficacy of HD0471953 : A novel GPR119 agonist for the treatment of type 2 diabetes mellitus. / 'T Hart, L. M.; Fritsche, A.; Nijpels, G.; Van Leeuwen, N.; Donnelly, L. A.; Dekker, J. M.; Alssema, M.; Fadista, J.; Carlotti, F.; Gjesing, A. P.; Palmer, C. N.; Van Haeften, T. W.; Herzberg-Schäfer, S. A.; Simonis-Bik, A. M.; Houwing-Duistermaat, J. J.; Helmer, Q.; Deelen, J.; Guigas, B.; Hansen, T.; MacHicao, F.; Willemsen, G.; Heine, R. J.; Kramer, M. H.; Holst, J. J.; De Koning, E. J.; Häring, H. U.; Pedersen, O.; Groop, L.; De Geus, E. J.; Slagboom, P. E.; Boomsma, D. I.; Eekhoff, E. M.; Pearson, E. R.; Diamant, M.

    In: Diabetes Technology & Therapeutics, Vol. 17, 01.02.2015, p. S131-S133.

    Research output: Contribution to journalComment/debateResearchpeer-review

  3. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. / 't Hart, Leen M; Fritsche, Andreas; Nijpels, Giel; van Leeuwen, Nienke; Donnelly, Louise A; Dekker, Jacqueline M; Alssema, Marjan; Fadista, Joao; Carlotti, Françoise; Gjesing, Anette P; Palmer, Colin N A; van Haeften, Timon W; Herzberg-Schäfer, Silke A; Simonis-Bik, Annemarie M C; Houwing-Duistermaat, Jeanine J; Helmer, Quinta; Deelen, Joris; Guigas, Bruno; Hansen, Torben; Machicao, Fausto; Willemsen, Gonneke; Heine, Robert J; Kramer, Mark; Holst, Jens Juul; de Koning, Eelco J P; Häring, Hans-Ulrich; Pedersen, Oluf; Groop, Leif; de Geus, Eco J C; Slagboom, P Eline; Boomsma, Dorret I; Eekhoff, Elisabeth M W; Pearson, Ewan R; Diamant, Michaela.

    In: Diabetes, Vol. 62, No. 9, 14.05.2013, p. 3275-3281.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus. / Aaboe, K; Knop, F K; Vilsbøll, T; Deacon, C F; Holst, Jens Juul; Madsbad, S; Krarup, Troels Magelund.

    In: Diabetes, Obesity and Metabolism, Vol. 12, No. 4, 01.04.2010, p. 323-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors. / Aaboe, K.; Akram, S.; Deacon, C. F.; Holst, J. J.; Madsbad, S.; Krarup, T.

    In: Diabetes, Obesity and Metabolism, Vol. 17, No. 1, 01.2015, p. 74-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    GLP-1: physiological effects and potential therapeutic applications. / Aaboe, Kasper; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul; Aaboe, Kasper; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul.

    In: Diabetic Medicine, Vol. 10, No. 11, 2008, p. 994-1003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    GLP-1 : physiological effects and potential therapeutic applications. / Aaboe, Kasper; Krarup, Thure; Madsbad, Sten; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism Online, Vol. 10, No. 11, 11.2008, p. 994-1003.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsboll, Tina; Vølund, Aage; Simonsen, Ulf; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2008, p. 603-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes. / Aaboe, Kasper; Knop, Filip Krag; Vilsbøll, Tina; Vølund, A; Simonsen, U; Deacon, Carolyn F.; Madsbad, Sten; Holst, Jens Juul; Krarup, Thure.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 94, No. 2, 2009, p. 603-608.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published
  12. Published

    Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets. / Adriaenssens, Alice E; Svendsen, Berit; Lam, Brian Y H; Yeo, Giles S H; Holst, Jens J; Reimann, Frank; Gribble, Fiona M.

    In: Diabetologia, Vol. 59, No. 10, 10.2016, p. 2156-2165.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterization of GLP-1 effects on beta cell function after meal ingestion in humans. / Ahren, B.; Holst, Jens Juul; Mari, A.

    In: Diabetes Care, No. 26, 2003, p. 2860-2864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Comparison of Glycomacropeptide with Phenylalanine Free-Synthetic Amino Acids in Test Meals to PKU Patients : No Significant Differences in Biomarkers, Including Plasma Phe Levels. / Ahring, Kirsten K.; Lund, Allan M.; Jensen, Erik; Jensen, Thomas G.; Brondum-Nielsen, Karen; Pedersen, Michael; Bardow, Allan; Holst, Jens Juul; Rehfeld, Jens F.; Moller, Lisbeth B.

    In: Journal of Nutrition and Metabolism, Vol. 2018, 6352919, 2018, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1. / Ahrén, B; Adner, N; Svartberg, J; Petrella, E; Holst, Jens Juul; Gutniak, M K.

    In: Diabetic Medicine, Vol. 19, No. 9, 09.2002, p. 790-2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance. / Ahrén, Bo; Larsson, H.; Holst, Jens Juul.

    In: European Journal of Endocrinology, No. 137, 1997, p. 127-131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Antidiabetogenic action of cholecystokinin in type 2 diabetes. / Ahrén, Bo; Holst, J.J.; Efendic, S.

    In: J. Clin. Endocrinol. Metab., No. 85, 2000, p. 1043-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia. / Ahrén, Bo; Holst, J.J.

    In: Diabetes, No. 50, 2001, p. 1030-1038.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans. / Ahrén, Bo; Holst, Jens Juul; Mari, Andrea.

    In: Diabetes Care. Supplement, Vol. 26, No. 10, 10.2003, p. 2860-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Improved glucagon tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice. / Ahrén, Bo; Holst, J.J.; Mårtensson, H.; Balkan, B.

    In: Eur. J. Pharmacol., No. 404, 2000, p. 239-245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in non-insulin dependent diabetes mellitus. / Ahrén, Bo; Larsson, H.; Holst, Jens Juul.

    In: J. Clin. Endocrinol. Metab., No. 82, 1997, p. 473-478.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    1,5-Anhydro fructose increase glucose tolerance by increasing GLP-1 and insulin in mice. / Ahrén, Bo; Holst, J.J.; Marcussen, J.; Yu, S.

    In: Eur. J. Pharmacol., No. 397, 2000, p. 219-225.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production. / Albrechtsen, Nicolai J. Wewer; Kuhre, Rune E.; Hornburg, Daniel; Jensen, Christian Z.; Hornum, Mads; Dirksen, Carsten; Svane, Maria; Gasbjerg, Laerke S.; Jorgensen, Nils B.; Gabe, Maria N.; Balk-Moller, Emilie; Albrechtsen, Reidar; Winther-Sorensen, Marie; Galsgaard, Katrine D.; Meissner, Felix; Jorsal, Tina; Lund, Asger; Vilsboll, Tina; Eliasen, Rasmus; Bojsen-Moller, Kirstine N.; Idorn, Thomas; Deacon, Carolyn F.; Knop, Filip K.; Rosenkilde, Mette M.; Hartmann, Bolette; Feldt-Rasmussen, Bo; Mann, Matthias; Madsbad, Sten; Holst, Jens J.

    In: Cell Reports, Vol. 21, No. 6, 11.2017, p. 1452-1460.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma. / Albrechtsen, Nicolai Jacob Wewer; Bak, Monika Judyta; Hartmann, Bolette; Christensen, Louise Wulff; Kuhre, Rune E; Deacon, Carolyn; Holst, Jens Juul.

    In: Endocrine Connections, Vol. 4, No. 1, 16.01.2015, p. 50-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Expert Review of Endocrinology & Metabolism, Vol. 9, No. 1, 01.01.2014, p. 61-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Windeløv, Johanne Agerlin; Ørgaard, Anne; Deacon, Carolyn F.; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 311, No. 2, 2016, p. E302-E309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published
  28. Published

    The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Toräng, Signe; Holst, Jens Juul.

    In: BMC Research Notes, Vol. 9, No. 1, 60, 02.02.2016, p. 1-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA : nonspecific interference or truly elevated levels? / Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Veedfald, Simon; Windeløv, Johanne A; Plamboeck, Astrid; Bojsen-Møller, Kirstine N; Idorn, Thomas; Feldt-Rasmussen, Bo; Knop, Filip K; Vilsbøll, Tina; Madsbad, Sten; Deacon, Carolyn F; Holst, Jens J.

    In: Diabetologia, Vol. 57, No. 9, 03.06.2014, p. 1919-1926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest. / Alibegovic, Amra C; Sonne, Mette P; Højbjerre, Lise; Hansen, Torben; Pedersen, Oluf; van Hall, Gerrit; Holst, Jens J; Stallknecht, Bente; Dela, Flemming; Vaag, Allan.

    In: Diabetes, Vol. 59, No. 4, 2010, p. 836-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Glucagon immunoneutralization in diabetic rats normalizes urea synthesis and decreases nitrogen wasting. / Almdal, Thomas Peter; Holst, Jens Juul; Vilstrup, H.

    In: Diabetes, No. 41, 1992, p. 12-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Genetic determinants of circulating GIP and GLP-1 concentrations. / Almgren, Peter; Lindqvist, Andreas; Krus, Ulrika; Hakaste, Liisa; Ottosson-Laakso, Emilia; Asplund, Olof; Sonestedt, Emily; Prasad, Rashmi B; Laurila, Esa; Orho-Melander, Marju; Melander, Olle; Tuomi, Tiinamaija; Holst, Jens Juul; Nilsson, Peter M; Wierup, Nils; Groop, Leif; Ahlqvist, Emma.

    In: JCI Insight, Vol. 2, No. 21, e93306, 02.11.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells. / Almind, K.; Ambye, Louise; Urhammer, S.A.; Hansen, T.; Echwald, S.M.; Holst, J.J.; Gromada, Jesper Lindgren; Thorens, B.; Pedersen, O.

    In: Diabetologia, No. 41, 1998, p. 1194-1198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT. / Alssema, Marjan; Rijkelijkhuizen, Josina M; Holst, Jens Juul; Teerlink, Tom; Scheffer, Peter G; Eekhoff, Elisabeth M W; Gastaldelli, Amalia; Mari, Andrea; Hart, Leen M't; Nijpels, Giel; Dekker, Jacqueline M.

    In: European Journal of Endocrinology, Vol. 169, No. 4, 10.2013, p. 421-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate. / Amin, H.; Holst, Jens Juul; Hartmann, B.; Wallace, L.; Wright, J.; Sigalet, D.L.

    In: Pediatrics, Vol. 121, No. 1, 2008, p. E180-E186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate. / Amin, Harish; Holst, Jens Juul; Hartmann, Bolette; Wallace, Laurie; Wright, Jim; Sigalet, David L.

    In: Pediatrics, Vol. 121, No. 1, 01.2008, p. e180-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes? / Andersen, Emilie S.; Lund, A.; Bagger, J. I.; Andreasen, C; Grøndahl, MF; Deacon, Carolyn F.; Hartmann, Bolette; Holst, Jens Juul; Knop, Filip Krag; Lauritsen, Tina Vilsbøll.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 8, 08.2018, p. 1937-1943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors? / Andersen, Emilie S.; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 1, 2018, p. 34-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy. / Andersen, O; Haugaard, S B; Holst, Jens Juul; Deacon, C F; Iversen, J; Andersen, U B; Nielsen, J O; Madsbad, S.

    In: HIV Medicine, Vol. 6, No. 2, 03.2005, p. 91-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy. / Andersen, O.; Haugaard, S.B.; Holst, Jens Juul; Deacon, Carolyn F.; Iversen, J.; Andersen, U.B.; Nielsen, J.O.; Madsbad, S.

    In: HIV Medicine, Vol. 6, 2005, p. 91-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Secretion of glucagon-like peptide-1 and reactive hypoglycemia after partial gastrectomy. / Andreasen, J.; Ørskov, Cathrine; Holst, Jens Juul.

    In: Digestion, No. 55, 1994, p. 221-228.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment. / Andreassen, B U; Paerregaard, A; Schmiegelow, K; Rechnitzer, C; Heilman, C; Hartmann, B; Holst, Jens Juul; Michaelsen, K F.

    In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 40, No. 1, 01.2005, p. 48-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Glucagon-like-peptide-2 (GLP-2) response to enteral intake in children during anticancer treatment. / Andreassen, B.U.; Pærregaard, A.; Schmiegelow, K.; Rechnitzer, C.; Hartmann, Bolette; Holst, Jens Juul; Michaelsen, K.F.

    In: Journal of Pediatric Gastroenterology and Nutrition, No. 40, 2005, p. 48-53.

    Research output: Contribution to journalJournal articleResearch

  44. Published

    Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects : a possible link between obesity and local tissue inflammation? / Arngrim, N; Simonsen, L; Holst, Jens Juul; Bülow, J.

    In: International Journal of Obesity, Vol. 37, 2012, p. 748-50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effect of glucagon-like peptide-2 exposure on bone resorption : Effectiveness of high concentration versus prolonged exposure. / Askov-Hansen, Carsten; Jeppesen, Palle B; Lund, Pernille; Hartmann, Bolette; Holst, Jens Juul; Henriksen, Dennis B.

    In: Regulatory Peptides, Vol. 181, 10.02.2013, p. 4-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1 : A Functional GLP-1–Renal Axis in Man. / Asmar, Ali; Cramon, Per K; Simonsen, Lene; Asmar, Meena; Sorensen, Charlotte M; Madsbad, Sten; Moro, Cedric; Hartmann, Bolette; Jensen, Boye L; Holst, Jens J; Bülow, Jens.

    In: The Journal of clinical endocrinology and metabolism, Vol. 104, No. 7, 07.2019, p. 2509–2519.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy. / Asmar, Ali; Simonsen, Lene; Asmar, Meena; Madsbad, Sten; Holst, Jens J; Frandsen, Erik; Moro, Cedric; Sorensen, Charlotte M; Jonassen, Thomas; Bulow, Jens.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 310, No. 9, 05.2016, p. E744-E753.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men. / Asmar, Ali; Simonsen, Lene; Asmar, Meena; Madsbad, Sten; Holst, Jens Juul; Frandsen, Erik; Moro, Cedric; Jonassen, Thomas; Bülow, Jens.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 308, No. 8, 15.04.2015, p. E641-E649.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men. / Asmar, Ali; Asmar, Meena; Simonsen, Lene; Madsbad, Sten; Holst, Jens J; Hartmann, Bolette; Sorensen, Charlotte M; Bülow, Jens.

    In: Physiological Reports, Vol. 5, No. 3, e13073, 02.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects. / Asmar, M; Simonsen, L; Arngrim, N; Holst, J J; Dela, F; Bülow, Jens.

    In: International journal of obesity (2005), Vol. 38, No. 2, 2013, p. 259-65.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss. / Asmar, M; Arngrim, N; Simonsen, L.; Asmar, A; Nordby, P; Holst, J J; Bülow, J.

    In: Nutrition and Diabetes, Vol. 6, e208, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. / Asmar, Meena; Højberg, Patricia; Deacon, Carolyn F.; Hare, Kristine; Holst, Jens Juul; Madsbad, Sten.

    In: Regulatory Peptides, Vol. 160, No. 1-3, 2010, p. 175-180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. / Asmar, Meena; Højberg, Patricia V; Deacon, Carolyn F; Hare, Kristine; Holst, Jens Juul; Madsbad, Sten.

    In: Regulatory Peptides, Vol. 160, No. 1-3, 2010, p. 175-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    GIP-induced vasodilation in human adipose tissue involves capillary recruitment. / Asmar, Meena; Asmar, Ali; Simonsen, Lene; Dela, Flemming; Holst, Jens Juul; Bulow, Jens.

    In: Endocrine Connections, Vol. 8, No. 6, 06.2019, p. 806-813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans. / Asmar, Meena; Simonsen, Lene; Asmar, Ali; Holst, Jens Juul; Dela, Flemming; Bülow, Jens.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 101, No. 8, 08.2016, p. 3155-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries (Retraction of Vol 104, Pg 16, 2019). / Asmar, Meena; Asmar, Ali; Simonsen, Lene; Holst, Jens Juul; Bulow, Jens.

    In: Journal of Clinical Endocrinology & Metabolism, Vol. 104, No. 1, 2019, p. W1-W9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor. / Asmar, Meena; Asmar, Ali; Simonsen, Lene; Gasbjerg, Lærke Smidt; Sparre-Ulrich, Alexander Hovard; Rosenkilde, Mette Marie; Hartmann, Bolette; Dela, Flemming; Holst, Jens Juul; Bülow, Jens.

    In: Diabetes, Vol. 66, No. 9, 09.2017, p. 2363-2371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances. / Asmar, Meena; Holst, Jens Juul.

    In: Current Opinion in Endocrinology, Diabetes and Obesity, Vol. 17, No. 1, 01.02.2010, p. 57-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans? / Asmar, Meena; Bache, Michael; Knop, Filip K; Madsbad, Sten; Holst, Jens Juul.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 5, 01.05.2010, p. 2367-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans. / Asmar, Meena; Simonsen, Lene; Madsbad, Sten; Stallknecht, Bente Merete; Holst, Jens Juul; Bülow, Jens.

    In: Diabetes, Vol. 59, No. 9, 01.09.2010, p. 2160-3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans. / Asmar, Meena; Tangaa, Winnie; Madsbad, Sten; Hare, Kristine; Astrup, Arne; Flint, Anne; Bülow, Jens; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 298, No. 3, 2010, p. E614-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade. / Aulinger, Benedikt A; Bedorf, Anne; Kutscherauer, Gabriele; de Heer, Jocelyn; Holst, Jens Juul; Göke, Burkhard; Schirra, Jörg.

    In: Diabetes, Vol. 63, No. 3, 03.2014, p. 1079-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus. / Azuma, K; Radikova, Z; Mancino, J; Toledo, FGS; Thomas, E; Kangani, C; Dalla Man, C; Cobelli, C; Holst, Jens Juul; Deacon, Carolyn F.; He, Y; Ligueros-Saylan, M; Serra, D; Kelley, DE.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, 2008, p. 459-463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes. / Azuma, Koichiro; Rádiková, Zofia; Mancino, Juliet; Toledo, Frederico G S; Thomas, Ernestine; Kangani, Cyrous; Dalla Man, Chiara; Cobelli, Claudio; Holst, Jens J; Deacon, Carolyn F; He, Yanling; Ligueros-Saylan, Monica; Serra, Denise; Foley, James E; Kelley, David E.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 2, 2007, p. 459-464.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Glucagon antagonism as a potential therapeutic target in type 2 diabetes. / Bagger, J I; Knop, F K; Holst, Jens Juul; Vilsbøll, T.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 11, 11.2011, p. 965-971.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Increased liver fat content in totally pancreatectomised patients. / Bagger, J. I.; Lund, A. B.; Albrechtsen, N. J. Wewer; Christensen, M.; Grøndahl, M. F.; Hansen, C. P.; Storkholm, J.; Holst, J. J.; Vilsboll, T.; Knop, F. K.

    In: Diabetologia, Vol. 60, 2017, p. S572-S573.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young. / Bagger, J. I.; Ostoft, S. H.; Hansen, T.; Pedersen, O.; Holst, J. J.; Knop, F. K.; Vilsboll, T.

    In: Diabetologia, Vol. 56, 2013, p. S152-S152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes. / Bagger, Jonatan I; Knop, Filip K; Lund, Asger; Vestergaard, Henrik; Holst, Jens Juul; Vilsbøll, Tina.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 3, 2011, p. 737-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure. / Bagger, Jonatan I; Holst, Jens J; Hartmann, Bolette; Andersen, Birgitte; Knop, Filip K; Vilsbøll, Tina.

    In: The Journal of Clinical Endocrinology & Metabolism, Vol. 100, No. 12, 2015, p. 4541–4552.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals. / Bagger, Jonatan I; Knop, Filip K; Lund, Asger; Holst, Jens Juul; Vilsbøll, Tina.

    In: Diabetologia, Vol. 57, No. 8, 31.05.2014, p. 1270-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes. / Bahne, Emilie; Sun, Emily W L; Young, Richard L; Hansen, Morten; Sonne, David P; Hansen, Jakob S; Rohde, Ulrich; Liou, Alice P; Jackson, Margaret L; de Fontgalland, Dayan; Rabbitt, Philippa; Hollington, Paul; Sposato, Luigi; Due, Steven; Wattchow, David A; Rehfeld, Jens F.; Holst, Jens J; Keating, Damien J; Vilsbøll, Tina; Knop, Filip K.

    In: JCI Insight, Vol. 3, No. 23, e93936, 2018, p. 1-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats. / Baidassano, Sara; Gasbjerg, Lwrke Smidt; Kizilkaya, Husun Sheyma; Rosenkilde, Mette Marie; Holst, Jens Juul; Hartmann, Bolette.

    In: Frontiers in Endocrinology, Vol. 10, 492, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1) : Implications for GLP-1 measurements in clinical studies. / Bak, Monika Judyta; Albrechtsen, Nicolai Jacob Wewer; Pedersen, Jens; Knop, Filip Krag; Vilsbøll Lauritsen, Tina; Jørgensen, Nils B; Hartmann, Bolette; Deacon, Carolyn F.; Dragsted, Lars Ove; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 16, No. 11, 2014, p. 1155-1164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans. / Bak, Monika Judyta; Wewer Albrechtsen, Nicolai Jacob; Pedersen, Jens; Hartmann, Bolette; Christensen, Mikkel; Vilsbøll, Tina; Knop, Filip Krag; Deacon, Carolyn F; Dragsted, Lars Ove; Holst, Jens Juul.

    In: European Journal of Endocrinology, Vol. 170, No. 4, 2014, p. 529-538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma. / Bak, Monika judyta; Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Pedersen, Jens; Christensen, Mikkel; Vilsboll, Tina; Knop, Filip Krag; Deacon, Carolyn Fiona; Dragsted, Lars Ove; Holst, Jens Juul.

    In: Journal of Endocrinology and Diabetes, Vol. 1, No. 1, 2014, p. 1-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing. / Bakhøj, S; Flint, A.; Holst, Jens Juul; Tetens, Inge.

    In: European Journal of Clinical Nutrition, Vol. 57, No. 10, 2003, p. 1254-1261.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. / Balas, Bogdan; Baig, Muhammad R; Watson, Catherine; Dunning, Beth E; Ligueros-Saylan, Monica; Wang, Yibin; He, Yan-Ling; Darland, Celia; Holst, Jens J; Deacon, Carolyn F; Cusi, Kenneth; Mari, Andrea; Foley, James E; DeFronzo, Ralph A.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 92, No. 4, 2007, p. 1249-55.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Incretin secretion: direct mechanisms. / Balk-Møller, Emilie; Holst, Jens Juul; Kuhre, Rune Ehrenreich.

    Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), 2014. p. 1-3.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  79. Published

    Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats. / Balkan, B.; Kwasnik, L.; Miserendino, R.; Holst, J.J.; Lie, X.

    In: Diabetologia, No. 42, 1999, p. 1324-1331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Glucagon-like peptide 2 inhibits ghrelin secretion in humans. / Banasch, Matthias; Bulut, Kerem; Hagemann, Dirk; Schrader, Henning; Holst, Jens Juul; Schmidt, Wolfgang E; Meier, Juris J.

    In: Regulatory Peptides, Vol. 137, No. 3, 10.12.2006, p. 173-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition : a randomized, prospective comparison of sitagliptin and vildagliptin treatment. / Baranov, Oleg; Kahle, Melanie; Deacon, Carolyn F; Holst, Jens J; Nauck, Michael A.

    In: Diabetes, Obesity and Metabolism, Vol. 18, No. 11, 11.2016, p. 1100-1109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model. / Barnes, Jennifer L; Hartmann, Bolette; Holst, Jens Juul; Tappenden, Kelly A.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 36, No. 5, 09.2012, p. 524-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs. / Bartholome, A.L.; Albin, D.M.; Baker, D.H.; Holst, J.J.; Tappenden, K.A.

    In: J Parenter Enteral Nutr, No. 28, 2004, p. 210-223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. / Bartholome, Anne L; Albin, David M; Baker, David H; Holst, Jens Juul; Tappenden, Kelly A.

    In: Journal of Parenteral and Enteral Nutrition, Vol. 28, No. 4, 05.08.2004, p. 210-22; discussion 222-3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes : A Randomized Single-Blinded Placebo Controlled Study. / Behary, Preeshila; Tharakan, George; Alexiadou, Kleopatra; Johnson, Nicholas; Albrechtsen, Nicolai Jacob Wewer; Kenkre, Julia; Cuenco, Joyceline; Hope, David; Anyiam, Oluwaseun; Choudhury, Sirazum; Alessimii, Haya; Poddar, Ankur; Minnion, James; Doyle, Chedie; Frost, Gary; Le Roux, Carel; Purkayastha, Sanjay; Moorthy, Krishna; Dhillo, Waljit; Holst, Jens J; Ahmed, Ahmed R; Prevost, A Toby; Bloom, Stephen R; Tan, Tricia M.

    In: Diabetes Care, Vol. 42, No. 7, dc190449, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Effects of hydrolysed casein, intact casein and intact whey protein on energy expenditure and appetite regulation : a randomised, controlled, cross-over study. / Bendtsen, Line Quist; Lorenzen, Janne Kunchel; Gomes, Sisse; Liaset, Bjørn; Holst, Jens Juul; Ritz, Christian; Reitelseder, Søren; Sjödin, Anders Mikael; Astrup, Arne.

    In: British Journal of Nutrition, Vol. 112, No. 8, 2014, p. 1412-1422.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    GLP-2 Delays But Does Not Prevent the Onset of Necrotizing Enterocolitis in Preterm Pigs. / Benight, Nancy M; Stoll, Barbara; Olutoye, Oluyinka O; Holst, Jens Juul; Burrin, Douglas G.

    In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 56, No. 6, 21.01.2013, p. 623-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption. / Bergmann, N. C.; Lund, A.; Heimburger, S. M.; Gasbjerg, L. S.; Jorgensen, N. R.; Jessen, L.; Hartmann, B.; Holst, J. J.; Christensen, M. B.; Vilsboll, T.; Knop, F. K.

    In: Diabetologia, Vol. 61, No. S.1, 717, 2018, p. S348-S348.

    Research output: Contribution to journalConference abstract in journalResearch

  89. Published

    Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals : a randomised, crossover study. / Bergmann, Natasha C; Lund, Asger; Gasbjerg, Lærke S; Meessen, Emma C E; Andersen, Maria M; Bergmann, Sigrid; Hartmann, Bolette; Holst, Jens J; Jessen, Lene; Christensen, Mikkel B; Vilsbøll, Tina; Knop, Filip K.

    In: Diabetologia, Vol. 62, No. 4, 2019, p. 665-675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes. / Bergmann, Natasha Chidekel; Lund, Asger; Gasbjerg, Lærke Smidt; Jørgensen, Niklas Rye; Jessen, Lene; Hartmann, Bolette; Holst, Jens Juul; Christensen, Mikkel Bring; Vilsbøll, Tina; Knop, Filip Krag.

    In: The Journal of clinical endocrinology and metabolism, Vol. 104, No. 7, 07.2019, p. 2953–2960.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Oxidation/reduction explains heterogeneity of pancreatic somatostatin. / Bersani, Maurizio; Johnsen, A.H.; Holst, Jens Juul.

    In: FEBS Letter, No. 279, no.2, 1991, p. 237-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Galanin and galanin extended at the N-terminus with 7 and 9 amino acids are produced in and secreted from the porcine adrenal medulla in almost equal amounts. / Bersani, Maurizio; Thim, Lars; Rasmussen, Torben Norre; Holst, Jens Juul.

    In: Endokrinologiya, No. 129, 1991, p. 2693-2698.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Human galanin: primary structure and identification of two molecular forms. / Bersani, Maurizio; Johnsen, A.H.; Højrup, P.; Dunning, B.E.; Holst, Jens Juul; Andreasen, J.J.

    In: FEBS Letters, No. 283, 1991, p. 189-194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects : A H2 15O positron emission tomographic study. / Bie-Olsen, Lise G; Kjaer, Troels W; Pedersen-Bjergaard, Ulrik; Lonsdale, Markus N; Holst, Jens Juul; Law, Ian; Thorsteinsson, Birger.

    In: Journal of Neuroscience Research, Vol. 87, No. 8, 06.2009, p. 1922-1928.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely. / Bjerg, Anne Toksvig; Kristensen, Mette Bredal; Ritz, Christian; Holst, Jens Juul; Rasmussen, Charlotte; Leser, Thomas Dyrmann; Wellejus, Anja; Astrup, Arne.

    In: Appetite, Vol. 82, 2014, p. 111-118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults. / Bjerg, Anne Toksvig; Kristensen, Mette Bredal; Ritz, Christian; Stark, K D; Holst, Jens Juul; Leser, Thomas Dyrmann; Wellejus, Anja; Astrup, Arne.

    In: Beneficial Microbes, Vol. 6, No. 1, 2015, p. 29-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. E-pub ahead of print

    Pre-meal and postprandial lipaemia in subjects with the metabolic syndrome : effects of timing and protein quality (randomised crossover trial). / Bjørnshave, Ann; Johansen, Trine Nygaard; Amer, Bashar; Dalsgaard, Trine Kastrup; Holst, Jens Juul; Hermansen, Kjeld.

    In: The British Journal of Nutrition, 02.01.2019, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    A pre-meal of whey proteins induces differential effects on glucose and lipid metabolism in subjects with the metabolic syndrome : a randomised cross-over trial. / Bjørnshave, Ann; Holst, Jens Juul; Hermansen, Kjeld.

    In: European Journal of Nutrition, Vol. 58, No. 2, 2019, p. 755-764.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Pre-Meal Effect of Whey Proteins on Metabolic Parameters in Subjects with and without Type 2 Diabetes : A Randomized, Crossover Trial. / Bjørnshave, Ann; Hermansen, Kjeld; Holst, Jens Juul.

    In: Nutrients, Vol. 10, No. 2, 122, 2018, p. 1-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Identification, characterization and release of GRP gene-associated peptides from the normal porcine and human gastro-intestinal tract. / Bjørnskov-Bartholdy, Leif; Bersani, Maurizio; Holst, Jens Juul.

    In: Regulatory Peptides, No. 34, 1991, p. 197-209.

    Research output: Contribution to journalJournal articleResearchpeer-review

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