Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects. / Westberg-Rasmussen, Sidse; Starup-Linde, Jakob; Hermansen, Kjeld; Holst, Jens Juul; Hartmann, Bolette; Vestergaard, Peter; Gregersen, Søren.

    In: Bone, Vol. 97, 04.2017, p. 261-266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis. / Edholm, T; Degerblad, M; Grybäck, P; Hilsted, L; Holst, Jens Juul; Jacobsson, H; Efendic, S; Schmidt, P T; Hellström, P M.

    In: Neurogastroenterology and Motility Online, Vol. 22, No. 11, 01.11.2010, p. 1191-200, e315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction. / Carstensen, Marius; Thomsen, Claus; Gotzsche, Ole; Holst, Jens Juul; Schrezenmeir, Jürgen; Hermansen, Kjeld.

    In: The review of diabetic studies : RDS, Vol. 1, No. 4, 2005, p. 175-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Differential regional metabolism of glucagon in anesthetized pigs. / Deacon, Carolyn F; Kelstrup, Mette; Trebbien, Ramona; Klarskov, Letty; Olesen, Mette; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 285, No. 3, 2003, p. E552-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective. / Deacon, Carolyn F; Holst, Jens J.

    In: Biochemical and Biophysical Research Communications, Vol. 294, No. 1, 2002, p. 1-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice. / Hartmann, B; Thulesen, J; Kissow, Hannelouise; Thulesen, S; Orskov, C; Ropke, C; Poulsen, S S; Holst, J J.

    In: Endocrinology, Vol. 141, No. 11, 2000, p. 4013-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig. / Deacon, C.F.; Hughes, T.E.; Holst, J.J.

    In: Diabetes, No. 47, 1998, p. 764-769.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs. / Deacon, C.F.; Danielsen, P.; Klarskov, L.; Holst, J.J.; Olesen, M.

    In: Diabetes, No. 50, 2001, p. 1588-1597.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens J.

    In: International Journal of Biochemistry & Cell Biology, Vol. 38, No. 5-6, 2005, p. 831-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity. / Deacon, C.F.; Knudsen, L.B.; Madsen, K.; Wiberg, F.C.; Jacobsen, O.; Holst, J.J.

    In: Diabetologia, No. 41, 1998, p. 271-278.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dipeptidyl peptidase expression during experimental colitis in mice. / Yazbeck, Roger; Sulda, Melanie L; Howarth, Gordon S; Bleich, Andre; Raber, Kerstin; von Hörsten, Stephan; Holst, Jens Juul; Abbott, Catherine A.

    In: Inflammatory Bowel Diseases, Vol. 16, No. 8, 01.08.2010, p. 1340-1351.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. / Hjøllund, K R; Deacon, C F; Holst, Jens Juul.

    In: Diabetologia, Vol. 54, No. 8, 2011, p. 2206-8.

    Research output: Contribution to journalLetterResearchpeer-review

  13. Published

    Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1. / Migoya, E M; Bergeron, R; Miller, J L; Snyder, R N K; Tanen, M; Hilliard, D; Weiss, B; Larson, P; Gutierrez, M; Jiang, G; Liu, F.; Pryor, K A; Yao, J; Zhu, L; Holst, Jens Juul; Deacon, C; Herman, G; Thornberry, N; Amatruda, J; Williams-Herman, D; Wagner, J A; SinhaRoy, R.

    In: Clinical Pharmacology and Therapeutics, Vol. 88, No. 6, 01.12.2010, p. 801-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes : comparison, efficacy and safety. / Deacon, Carolyn F; Holst, Jens Juul.

    In: Expert Opinion on Pharmacotherapy, Vol. 14, No. 15, 10.2013, p. 2047-58.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Disassociation of bone resorption and formation by GLP-2 : a 14-day study in healthy postmenopausal women. / Henriksen, Dennis B; Alexandersen, Peter; Hartmann, Bolette; Adrian, Charlotte L; Byrjalsen, Inger; Bone, Henry G; Holst, Jens Juul; Christiansen, Claus.

    In: Bone, Vol. 40, No. 3, 03.2007, p. 723-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Disassociation of bone resorption and formation by GLP-2 - A 14-day study in healthy postmenopausal women. / Henriksen, D.B.; Alexandersen, P.; Hartmann, B.; Adrian, C.L.; Byrjalsen, I.; Bone, H.G.; Holst, J.J.; Christiansen, C.

    In: Bone, Vol. 40, No. 3, 2007, p. 723-729.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells. / Almind, K.; Ambye, Louise; Urhammer, S.A.; Hansen, T.; Echwald, S.M.; Holst, J.J.; Gromada, Jesper Lindgren; Thorens, B.; Pedersen, O.

    In: Diabetologia, No. 41, 1998, p. 1194-1198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Discovery, characterization, and clinical development of the glucagon-like peptides. / Drucker, Daniel J; Habener, Joel F; Holst, Jens Juul.

    In: The Journal of Clinical Investigation, Vol. 127, No. 12, 01.12.2017, p. 4217-4227.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. / Zhu, Xiaorong; Zhou, An; Dey, Arunangsu; Norrbom, Christina; Carroll, Raymond; Zhang, Chunling; Laurent, Virginie; Lindberg, Iris; Ugleholdt, Randi; Holst, Jens Juul; Steiner, Donald F.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 16, 06.08.2002, p. 10293-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Disruption of glucagon receptor signaling causes hyperaminoacidemia exposing a possible liver-alpha-cell axis. / Galsgaard, Katrine D.; Winther-Sørensen, Marie; Ørskov, Cathrine; Kissow, Hannelouise; Poulsen, Steen S.; Vilstrup, Hendrik; Prehn, Cornelia; Adamski, Jerzy; Jepsen, Sara L.; Hartmann, Bolette; Hunt, Jenna; Charron, Maureen J; Pedersen, Jens; Albrechtsen, Nicolai J. Wewer; Holst, Jens J.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 314, No. 1, 2018, p. E93-E103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Dissociated incretin hormone response to protein versus fat ingestion in obese subjects. / Lindgren, O; Carr, RD; Holst, Jens Juul; Deacon, Carolyn F.; Ahren, B.

    In: Diabetes, Obesity and Metabolism Online, Vol. 13, No. 9, 07.2011, p. 863-865.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery. / Guldstrand, M; Ahrén, B; Näslund, E; Holst, Jens Juul; Adamson, U.

    In: Diabetes, Obesity and Metabolism, Vol. 11, No. 11, 2009, p. 1027-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity. / Harmuth, Stefan; Wewalka, Marlene; Holst, Jens Juul; Nemecek, Romina; Thalhammer, Sabine; Schmid, Rainer; Sahora, Klaus; Gnant, Michael; Miholić, Johannes.

    In: Journal of Gastrointestinal Surgery, Vol. 18, No. 1, 01.2014, p. 52-9.

    Research output: Contribution to journalConference articleResearchpeer-review

  24. Published

    Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying. / Naslund, E.; Gryback, P.; Backman, L.; Jacobsson, H.; Holst, J.J.; Theodorsson, E.; Hellstrom, P.M.

    In: Dig. Dis. Sci., No. 43, 1998, p. 945-952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men. / van der Beek, Christina M; Canfora, Emanuel E; Lenaerts, Kaatje; Troost, Freddy J; Damink, Steven W M Olde; Holst, Jens J; Masclee, Ad A M; Dejong, Cornelis H C; Blaak, Ellen E.

    In: Clinical Science, Vol. 130, No. 22, 11.10.2016, p. 2073-2082.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility. / Miki, Takashi; Minami, Kohtaro; Shinozaki, Hidehiro; Matsumura, Kimio; Saraya, Atsunori; Ikeda, Hiroki; Yamada, Yuichiro; Holst, Jens Juul; Seino, Susumu.

    In: Diabetes, Vol. 54, No. 4, 2005, p. 1056-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Distribution and characterization of different molecular products of Pro-somatostatin in the hypothalmus and posterior pituitary lobe of the mongolian gerbil (Meriones unguiculatus). / Larsen, Philip J.; Bersani, Maurizio; Holst, Jens Juul; Møller, Morten; Mikkelsen, J.D.

    In: Journal of Neuroscience, No. 12, hæfte 3, 1992, p. 946-961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem. / Larsen, Philip J.; Tang-Christensen, M.; Holst, Jens Juul; Ørskov, C.

    In: Neuroscience, No. Vol. 77, No. 1, 1997, p. 257-270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis. / Gyldenløve, M; Lauritsen, Tina Vilsbøll; Holst, Jens Juul; Zachariae, C; Skov, L; Knop, F K.

    In: British Journal of Dermatology, Vol. 175, No. 5, 11.2016, p. 1085–1088.

    Research output: Contribution to journalLetterResearchpeer-review

  30. Published

    Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women. / Raben, A.; Holst, Jens Juul; Madsen, J.; Astrup, A.

    In: American Journal of Clinical Nutrition, Vol. 73, 2001, p. 177-89.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Do glucagonomas always produce glucagon? / Wewer Albrechtsen, Nicolai Jacob; Challis, Benjamin; Damjanov, Ivan; Holst, Jens Juul.

    In: Bosnian Journal of Basic Medical Sciences, Vol. 16, No. 1, 01.02.2016, p. 1-7.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans? / Asmar, Meena; Bache, Michael; Knop, Filip K; Madsbad, Sten; Holst, Jens Juul.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 5, 01.05.2010, p. 2367-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors? / Andersen, Emilie S.; Deacon, Carolyn F.; Holst, Jens Juul.

    In: Diabetes, Obesity and Metabolism, Vol. 20, No. 1, 2018, p. 34-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial. / Larsen, Julie Rask; Vedtofte, Louise; Holst, Jens Juul; Oturai, Peter; Kjær, Andreas; Corell, Christoph U; Vilsbøll, Tina; Fink-Jensen, Anders.

    In: B M J Open, Vol. 4, No. 3, e004227, 2014, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes. / Staehr, P.; Højlund, K.; Hother-Nielsen, O.; Holst, Jens Juul; Beck-Nielsen, H.

    In: Diabetic Medicine, No. 20, 2003, p. 816-822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus. / Torekov, Signe Sørensen; Holst, J J; Ehlers, M R.

    In: Diabetes, Obesity and Metabolism, Vol. 16, No. 5, 05.2014, p. 451-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes. / Torekov, Signe Sørensen; Kipnes, M S; Harley, R E; Holst, J J; Ehlers, M R.

    In: Diabetes, Obesity and Metabolism, Vol. 13, No. 7, 2011, p. 639-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors. / Hansotia, T.; Baggio, L.L.; Delmeire, D.; Hinke, S.A.; Yamada, Y.; Tsukiyama, K.; Seino, Y.; Holst, J.J.; Schuit, F.; Drucker, D.J.

    In: Diabetes, No. 53, 2004, p. 1326-1335.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors. / Hansotia, Tanya; Baggio, Laurie L; Delmeire, Dominique; Hinke, Simon A; Yamada, Yuichiro; Tsukiyama, Katsushi; Seino, Yutaka; Holst, Jens Juul; Schuit, Frans; Drucker, D J.

    In: Diabetes, Vol. 53, No. 5, 05.2004, p. 1326-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes. / Reiband, H K; Schmidt, S; Ranjan, Ajenthen; Holst, Jens Juul; Madsbad, S; Nørgaard, K.

    In: Diabetes - Metabolism: Research and Reviews (Print Edition), Vol. 31, No. 7, 2015, p. 672-9.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes. / Albrechtsen, Nicolai Jacob Wewer; Kuhre, Rune Ehrenreich; Windeløv, Johanne Agerlin; Ørgaard, Anne; Deacon, Carolyn F.; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 311, No. 2, 2016, p. E302-E309.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight. / Jensen, Christine B; Storgaard, Heidi; Dela, Flemming; Holst, Jens Juul; Madsbad, Sten; Vaag, Allan A.

    In: Diabetes, Vol. 51, No. 4, 2002, p. 1271-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass. / Bojsen-Møller, Kirstine N; Dirksen, Carsten; Jørgensen, Nils Bruun; Jacobsen, Siv Hesse; Serup, Annette Karen Lundbeck; Albers, Peter Hjorth; Hansen, Dorte L; Worm, Dorte; Naver, Lars; Kristiansen, Viggo B; Wojtaszewski, Jørgen; Kiens, Bente; Holst, Jens J; Richter, Erik; Madsbad, Sten.

    In: Diabetes, Vol. 63, No. 5, 2014, p. 1725-1737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs. / Shen, René Liang; Thymann, Thomas; Østergaard, Mette Viberg; Støy, Ann Cathrine Findal; Krych, Lukasz; Nielsen, Dennis Sandris; Lauridsen, Charlotte; Hartmann, Bolette; Holst, Jens Juul; Burrin, Douglas G.; Sangild, Per Torp.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 309, No. 5, 2015, p. G310-G323.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Early growth and postprandial appetite regulatory hormone responses. / Perälä, Mia-Maria; Kajantie, Eero; Valsta, Liisa M; Holst, Jens Juul; Leiviskä, Jaana; Eriksson, Johan G.

    In: British Journal of Nutrition, Vol. 110, No. 09, 19.04.2013, p. 1-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients. / Yabe, Daisuke; Kuroe, Akira; Watanabe, Koin; Iwasaki, Masahiro; Hamasaki, Akihiro; Hamamoto, Yoshiyuki; Harada, Norio; Yamane, Shunsuke; Lee, Soushou; Murotani, Kenta; Deacon, Carolyn F; Holst, Jens Juul; Hirano, Tsutomu; Inagaki, Nobuya; Kurose, Takeshi; Seino, Yutaka.

    In: Journal of Diabetes and its Complications, Vol. 29, 2015, p. 413-421.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS. / Holle, G.E.; Steinbach, E.; Wünsch, E.; Holst, Jens Juul.

    In: Am. J. Physiol., No. 269, 1995, p. G584-G590.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. / Zander, Mette; Madsbad, Sten; Madsen, Jan Lysgaard; Holst, Jens Juul.

    In: Lancet, Vol. 359, No. 9309, 2002, p. 824-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism. / Mikkelsen, Kristian H; Frost, Morten; Bahl, Martin I; Licht, Tine R; Jensen, Ulrich S; Rosenberg, Jacob; Pedersen, Oluf; Hansen, Torben; Rehfeld, Jens F; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K.

    In: PLOS ONE, Vol. 10, No. 11, e0142352, 12.11.2015, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Effect of GLP-1 Receptor Agonist Treatment on Body weight in Obese Antipsychotic-treated Patients with Schizophrenia : a Randomized, Placebo-controlled Trial Byline. / Ishøy, Pelle L; Knop, Filip K; Broberg, Brian V; Bak, Nikolaj; Andersen, Ulrik B; Jørgensen, Niklas R; Holst, Jens J; Glenthøj, Birte Y; Ebdrup, Bjørn H.

    In: Diabetes, Obesity and Metabolism, Vol. 19, No. 2, 02.2017, p. 162-171.

    Research output: Contribution to journalJournal articleResearchpeer-review

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