Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young. / Østoft, Signe Harring; Bagger, Jonatan Ising; Hansen, Torben; Hartmann, Bolette; Pedersen, Oluf; Holst, Jens Juul; Knop, Filip Krag; Vilsbøll, Tina.

    In: European Journal of Endocrinology, Vol. 173, No. 2, 01.08.2015, p. 205-215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors. / Ørskov, Cathrine; Hartmann, Bolette; Poulsen, Steen Seier; Thulesen, Jesper; Hare, Kristine Juul; Holst, Jens Juul.

    In: Regulatory Peptides, Vol. 124, No. 1-3, 2005, p. 105-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans. / Ørskov, Cathrine; Rabenhøj, L.; Wettergren, André; Kofod, H.; Holst, Jens Juul.

    In: Diabetes, No. 43, 1994, p. 535-539.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    All products of proglucagon are elevated in plasma from ureamic patients. / Ørskov, Cathrine; Andreasen, Jan; Holst, Jens Juul.

    In: Journal of Clinical Endocrinology and Metabolism, No. 79, 1992, p. 379-383.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man. / Ørskov, Cathrine; Rabenhøj, L.; Kofod, H.; Wettergren, A.; Holst, Jens Juul.

    In: Diabetes, No. 43, 1994, p. 535-39.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable. / Ørskov, Cathrine; Wettergren, André; Holst, Jens Juul.

    In: Diabetes, No. 42, 1993, p. 658-661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting-state and after oral glucose and intravenous arginine. / Ørskov, Cathrine; Jeppesen, J.; Madsbad, J.; Holst, Jens Juul.

    In: J. Clin. Invest., No. 87, 1991, p. 415-423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Proglucagon products in plasma of uraemic patients and normals in the fasting state. / Ørskov, Cathrine; Andreasen, J.; Holst, Jens Juul.

    In: J. Clin. Endocrinol. Metab., No. 74, 1992, p. 379-384.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract. / Ørskov, C.; Holst, J.J.

    Nitric Oxide and the Peripheral Nervous System. London, UK : Portland Press Ltd., 2000. p. 131.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  10. Published

    Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects. / Ørskov, C.; Holst, Jens Juul.

    Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, 1995. p. 513-516.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  11. Published

    The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice. / Ørgaard, Anne; Holst, Jens J.

    In: Diabetologia, Vol. 60, No. 9, 09.2017, p. 1731-1739.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man. / Øktedalen, O.; Opstad, P.K.; Holst, Jens Juul.

    In: Scandinavian Journal of Gastroenterology, No. 28, 1993, p. 652-656.

    Research output: Contribution to journalJournal articleResearch

  13. Published

    Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets. / van der Meer, Y; Gerrits, W J J; van den Bosch, M; Holst, Jens Juul; Moreto, M; Buurman, W A; Kulik, W; van Kempen, T A T G.

    In: Journal of Animal Science, Vol. 90 Suppl 4, 12.2012, p. 302-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men. / van der Beek, Christina M.; Canfora, Emanuel E.; Kip, Anna M.; Gorissen, Stefan H. M.; Damink, Steven W. M. Olde; van Eijk, Hans M.; Holst, Jens J.; Blaak, Ellen E.; Dejong, Cornelis H. C.; Lenaerts, Kaatje.

    In: Metabolism, Vol. 87, 10.2018, p. 25-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men. / van der Beek, Christina M; Canfora, Emanuel E; Lenaerts, Kaatje; Troost, Freddy J; Damink, Steven W M Olde; Holst, Jens J; Masclee, Ad A M; Dejong, Cornelis H C; Blaak, Ellen E.

    In: Clinical Science, Vol. 130, No. 22, 11.10.2016, p. 2073-2082.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Islet-cell dysfunction induced by glucocorticoid treatment : potential role for altered sympathovagal balance? / van Raalte, Daniël H; Kwa, Kelly A A; van Genugten, Renate E; Tushuizen, Maarten E; Holst, Jens Juul; Deacon, Carolyn F; Karemaker, John M; Heine, Robert J; Mari, Andrea; Diamant, Michaela.

    In: Metabolism, Vol. 62, No. 4, 2013, p. 568-577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance. / van Poppel, P C M; van Asseldonk, E J P; Holst, Jens Juul; Vilsbøll, Tina ; Netea, M G; Tack, C J.

    In: Diabetes, Obesity and Metabolism, Vol. 16, No. 12, 12.2014, p. 1269-73.

    Research output: Contribution to journalLetterResearchpeer-review

  18. Published

    Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets. / le Huërou-Luron, I.; Petersen, Y.M.; Hartmann, B.; Holst, Jens Juul; Sangild, P.T.

    Ikke angivet. ed. / R.O. Ball. 2. ed. University of Alberta Press, 2003. p. 164-166.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  19. Published

    Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1. / de Heer, Jocelyn; Holst, Jens J.

    In: Diabetes, Vol. 56, No. 2, 2007, p. 438-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. / de Heer, J; Rasmussen, C; Coy, D H; Holst, Jens Juul.

    In: Diabetologia, Vol. 51, No. 12, 12.2008, p. 2263-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas. / de Heer, J; Pedersen, J; Orskov, C; Holst, Jens Juul.

    In: Diabetologia, Vol. 50, No. 10, 10.2007, p. 2135-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bile acid mediated effects on gut integrity and performance of early-weaned piglets. / de Diego-Cabero, Nuria; Mereu, Alessandro; Menoyo, David; Holst, Jens Juul; Ipharraguerre, Ignacio R.

    In: B M C Veterinary Research, Vol. 11, No. 1, 111, 2015, p. 1-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. / de, Heer J.; Rasmussen, C.; Coy, D.H.; Holst, Jens Juul.

    In: Diabetologia, Vol. 51, No. 12, 2008, p. 2263-2270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Circulating leptin and thyroid dysfunction. / Zimmermann-Belsing, Tina; Brabant, Georg; Holst, Jens Juul; Feldt-Rasmussen, Ulla.

    In: European Journal of Endocrinology, Vol. 149, No. 4, 2003, p. 257-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Changes in serum leptin do not correlate to total fat mass in patients with thyrotoxicosis. / Zimmermann-Belsing, T.; Dreyer, M.; Holst, J.J.; Feldt-Rasmussen, U.

    In: J. Endocrinol., No. 49, 1998, p. 589-595.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effect of viscosity on appetite and gastro-intestinal hormones. / Zijlstra, Nicolien; Mars, Monica; de Wijk, René A; Westerterp-Plantenga, Margriet S; Holst, Jens Juul; de Graaf, Cees.

    In: Physiology & Behavior, Vol. 97, No. 1, 2009, p. 68-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. / Zhu, Xiaorong; Zhou, An; Dey, Arunangsu; Norrbom, Christina; Carroll, Raymond; Zhang, Chunling; Laurent, Virginie; Lindberg, Iris; Ugleholdt, Randi; Holst, Jens Juul; Steiner, Donald F.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 16, 06.08.2002, p. 10293-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. / Zander, Mette; Madsbad, Sten; Madsen, Jan Lysgaard; Holst, Jens Juul.

    In: Lancet, Vol. 359, No. 9309, 2002, p. 824-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes. / Zander, Mette; Christiansen, Allan; Madsbad, Sten; Holst, Jens Juul.

    In: Diabetes Care, Vol. 27, No. 8, 2004, p. 1910-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Additive glucose-lowering effects of glucagon-like peptide- 1 and metformin type 2 diabetes. / Zander, M.; Taskiran, M.; Toft-Nielsen, M.B.; Holst, J.J.

    In: Diabetes Care, No. 24, 2001, p. 720-725.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes. / Zander, M.; Madsbad, S.; Deacon, C.F.; Holst, J.J.

    In: Diabetologia, Vol. 49, No. 2, 2006, p. 369-374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes. / Zander, M; Madsbad, S; Deacon, C F; Holst, Jens Juul.

    In: Diabetologia, Vol. 49, No. 2, 02.2006, p. 369-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Effects of Gastric Bypass and Gastric Banding on Bone Remodeling in Obese Patients with Type 2 Diabetes. / Yu, Elaine W; Wewalka, Marlene; Ding, Su-Ann; Simonson, Donald C; Foster, Kathleen; Holst, Jens J; Vernon, Ashley; Goldfine, Allison B; Halperin, Florencia.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 101, No. 2, 02.2016, p. 714–722.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young Asians with type 2 diabetes mellitus. / Yeow, Toh Peng; Pacini, Giovanni; Tura, Andrea; Hor, Chee Peng; Lim, Shueh Lin; Tan, Florence Hui Sieng; Tong, Chin Voon; Hong, Janet Yeow Hua; Md Zain, Fuziah; Holst, Jens Juul; Wan Mohamud, Wan Nazaimoon.

    In: BMJ open diabetes research & care, Vol. 5, No. 1, e000352, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Dipeptidyl peptidase expression during experimental colitis in mice. / Yazbeck, Roger; Sulda, Melanie L; Howarth, Gordon S; Bleich, Andre; Raber, Kerstin; von Hörsten, Stephan; Holst, Jens Juul; Abbott, Catherine A.

    In: Inflammatory Bowel Diseases, Vol. 16, No. 8, 01.08.2010, p. 1340-1351.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese : Comparison of type 2 diabetes patients and healthy controls. / Yabe, Daisuke; Kuroe, Akira; Lee, Soushou; Watanabe, Koin; Hyo, Takanori; Hishizawa, Masahiro; Kurose, Takeshi; Deacon, Carolyn F; Holst, Jens Juul; Hirano, Tsutomu; Inagaki, Nobuya; Seino, Yutaka.

    In: Journal of Diabetes Investigation, Vol. 1, No. 1-2, 22.04.2010, p. 56-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients. / Yabe, Daisuke; Kuroe, Akira; Watanabe, Koin; Iwasaki, Masahiro; Hamasaki, Akihiro; Hamamoto, Yoshiyuki; Harada, Norio; Yamane, Shunsuke; Lee, Soushou; Murotani, Kenta; Deacon, Carolyn F; Holst, Jens Juul; Hirano, Tsutomu; Inagaki, Nobuya; Kurose, Takeshi; Seino, Yutaka.

    In: Journal of Diabetes and its Complications, Vol. 29, 2015, p. 413-421.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls. / Yabe, D; Kuroe, A; Lee, S; Watanabe, K; Hyo, T; Hishizawa, M; Kurose, T; Deacon, Carolyn F.; Holst, Jens Juul; Hirano, T; Inagaki, N; Seino, Y.

    In: Journal of Diabetes Investigation, Vol. 1, No. 1/2, 01.2010, p. 56-59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition. / Xiao, Weidong; Feng, Yongjia; Holst, Jens Juul; Hartmann, Bolette; Yang, Hua; Teitelbaum, Daniel H.

    In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, No. 5, 05.2014, p. 2073-87.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Human gastric lipase secretion is inhibited by intraduodenal perfusion of dietary fat. / Wøjdemann, M.; Riber, C.; Bisgaard, T.; Sternby, B.; Larsen, S.; Rehfeld, J.F.; Holst, J.J.; Olesen, O.

    In: Regulatory Peptides, No. 80, 1999, p. 101-106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2. / Wøjdemann, M.; Wettergren, A.; Hartmann, B.; Hilsted, L.M.; Holst, J.J.

    In: J. Clin. Endocrinol. Metab., No. 84, 1999, p. 2513-2517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs. / Wojdemann, M.; Wettergren, A.; Hartmann, Bolette; Holst, J.J.

    In: Scandinavian Journal of Gastroenterology, No. 33, 1998, p. 828-832.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Inhibition of human gastric lipase secretion by glucagon-like peptide-1. / Wojdemann, M.; Wettergren, A.; Sternby, B.; Holst, J.J.; Larsen, S.; Rehfeld, J.F.; Olsen, O.

    In: Dig. Dis. Sci., No. 43, 1998, p. 799-805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion. / Witte, Anne-Barbara; Grybäck, Per; Jacobsson, Hans; Näslund, Erik; Hellström, Per Martin; Holst, Jens Juul; Hilsted, Linda; Schmidt, Peter Thelin.

    In: Scandinavian Journal of Gastroenterology. Supplement, Vol. 46, No. 4, 2011, p. 428-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation. / Witte, Anne-Barbara; Hilsted, Linda; Holst, Jens Juul; Schmidt, Peter Thelin.

    In: Scandinavian Journal of Gastroenterology, Vol. 51, No. 4, 04.2016, p. 400-409.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man. / Witte, A-B; Grybäck, P; Holst, Jens Juul; Hilsted, L; Hellström, P M; Jacobsson, H; Schmidt, P T.

    In: Regulatory Peptides, Vol. 158, No. 1-3, 2009, p. 57-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Why is it so difficult to measure glucagon-like peptide-1 in a mouse? / Windeløv, Johanne A; Wewer Albrechtsen, Nicolai J; Kuhre, Rune E; Jepsen, Sara L; Hornburg, Daniel; Pedersen, Jens; Jensen, Elisa P; Galsgaard, Katrine D; Winther-Sørensen, Marie; Ørgaard, Anne; Deacon, Carolyn F; Mann, Matthias; Kissow, Hannelouise; Hartmann, Bolette; Holst, Jens J.

    In: Diabetologia, Vol. 60, No. 10, 10.2017, p. 2066-2075.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice. / Windeløv, Johanne A; Pedersen, Jens; Holst, Jens J.

    In: Physiological Reports, Vol. 4, No. 11, e12824, 06.2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients. / Willms, B.; Idowu, K.; Holst, J.J.; Creutzfeldt, W.; Nauck, M.A.

    In: Exp. Clin. Endocrinol. Diabetes, No. 106, 1998, p. 103-107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Gastric emptying, glucose responses, and insulin secretion after a liquid test meal : effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients. / Willms, B; Werner, J; Holst, J J; Orskov, C; Creutzfeldt, W; Nauck, M A.

    In: Endocrinology, Vol. 81, No. 1, 01.1996, p. 327-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

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