Jens Juul Holst
Professor
Integrative Metabolism and Environmental Influences
Blegdamsvej 3B
2200 København N
Denmark
Blegdamsvej 3B
København N København N
Endocrinology and Metabolism
Blegdamsvej 3B, 2200 København N
Juul Holst Group
Blegdamsvej 3B, 2200 København N
- Published
Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine. / Christensen, Louise Wulff; Kuhre, Rune Ehrenreich; Janus, Charlotte; Svendsen, Berit; Holst, Jens Juul.
In: Physiological Reports, Vol. 3, No. 9, e122551, 17.09.2015, p. 1-13.Research output: Contribution to journal › Journal article › Research › peer-review
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Updates in weight loss surgery and gastrointestinal peptides. / Svane, Maria Saur; Bojsen-Møller, Kirstine N; Madsbad, Sten; Holst, Jens Juul.
In: Current Opinion in Endocrinology, Diabetes and Obesity, Vol. 22, No. 1, 02.2015, p. 21-8.Research output: Contribution to journal › Review › Research › peer-review
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Type 2 diabetes mellitus. / DeFronzo, Ralph A; Ferrannini, Ele; Groop, Leif; Henry, Robert R; Herman, William H; Holst, Jens Juul; Hu, Frank B; Kahn, C Ronald; Raz, Itamar; Shulmann, Gerald I.; Simonson, Donald C; Testa, Marcia A; Weiss, Ram.
In: Nature Reviews. Disease Primers, Vol. 1, 15019, 2015.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes : A Randomized, Placebo-Controlled, Double-Blind Parallel Study. / Frandsen, Christian S ; Dejgaard, Thomas F; Holst, Jens J; Andersen, Henrik U; Thorsteinsson, Birger; Madsbad, Sten.
In: Diabetes Care, Vol. 38, No. 12, 12.2015, p. 2250-7.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss. / Iepsen, E W; Lundgren, J; Dirksen, C; Jensen, J-Eb; Pedersen, O; Hansen, T; Madsbad, S; Holst, J J; Torekov, S S.
In: International journal of obesity (2005), Vol. 39, No. 5, 2015, p. 834-41.Research output: Contribution to journal › Journal article › Research › peer-review
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Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes. / Christensen, M; Sparre-Ulrich, A H; Hartmann, B; Grevstad, U; Rosenkilde, M M; Holst, J J; Vilsbøll, T; Knop, F K.
In: International journal of obesity (2005), Vol. 39, No. 11, 11.2015, p. 1651-1654.Research output: Contribution to journal › Letter › Research › peer-review
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Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells. / Egerod, Kristoffer L; Engelstoft, Maja S; Lund, Mari L; Grunddal, Kaare V; Zhao, Mirabella; Barir-Jensen, Dominique; Nygaard, Eva B; Petersen, Natalia; Holst, Jens J; Schwartz, Thue W.
In: Endocrinology, Vol. 156, No. 11, 11.2015, p. 3909-23.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure of wheat bread influences the postprandial metabolic response in healthy men. / Eelderink, Coby; Noort, Martijn W J; Sozer, Nesli; Koehorst, Martijn; Holst, Jens J; Deacon, Carolyn F; Rehfeld, Jens F; Poutanen, Kaisa; Vonk, Roel J; Oudhuis, Lizette; Priebe, Marion G.
In: Food & Function, Vol. 6, No. 10, 10.2015, p. 3236-48.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1. / Plamboeck, Astrid; Veedfald, Simon; Deacon, Carolyn F; Hartmann, Bolette; Vilsbøll, Tina; Knop, Filip K; Holst, Jens J.
In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Vol. 309, No. 5, 09.2015, p. R544-51.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes. / Fredheim, Siri; Andersen, Marie-Louise M; Pörksen, Sven; Nielsen, Lotte B; Pipper, Christian; Hansen, Lars; Holst, Jens Juul; Thomsen, Jane; Johannesen, Jesper; Mortensen, Henrik B; Svensson, Jannet.
In: Diabetologia, Vol. 58, No. 4, 2015, p. 828-34.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure : A pilot study. / Hvistendahl, Mark; Brandt, Christopher F.; Tribler, Siri; Naimi, Rahim; Hartmann, Bolette; Holst, Jens Juul; Rehfeld, Jens Frederik; Hornum, Mads; Andersen, Jens Rikardt; Mortensen, Per B.; Jeppesen, Palle B.
2015. Abstract from Årsmøde i Dansk Selskab for Klinisk Ernæring, Aarhus, Denmark.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine. / Pedersen, Jens; B. Pedersen, Nis; Brix, Sophie W.; Grunddal, Kaare Villum; Rosenkilde, Mette M.; Hartmann, Bolette; Ørskov, Cathrine; S. Poulsen, Steen; Holst, Jens J.
In: Peptides, Vol. 67, 05.2015, p. 20-28.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics. / Lehrskov-Schmidt, Louise; Lehrskov-Schmidt, Lars; Nielsen, Signe T; Holst, Jens Juul; Møller, Kirsten; Solomon, Thomas P J.
In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 4, 04.2015, p. E616-E622.Research output: Contribution to journal › Journal article › Research › peer-review
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The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo. / Toräng, Signe; Veedfald, Simon; Rosenkilde, Mette Marie; Hartmann, Bolette; Holst, Jens Juul.
In: Physiological Reports, Vol. 3, No. 7, e12455, 20.07.2015, p. 1-8.Research output: Contribution to journal › Journal article › Research › peer-review
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The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas. / Christiansen, Charlotte Bayer; Svendsen, B; Holst, Jens Juul.
In: Hormone and Metabolic Research, Vol. 47, No. 07, 20.01.2015, p. 537-43.Research output: Contribution to journal › Journal article › Research › peer-review
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The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass : A Case Report. / Craig, CM; Lamendola, C; Holst, Jens Juul; Deacon, Carolyn F.; McLaughlin, TL.
In: aace clinical case reports, Vol. 1, No. 2, 2015, p. e84-e87.Research output: Contribution to journal › Journal article › Research › peer-review
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The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans. / Mandøe, Mette J.; Hansen, Katrine B.; Hartmann, Bolette; Rehfeld, Jens F.; Holst, Jens J.; Hansen, Harald S.
In: The American Journal of Clinical Nutrition, Vol. 102, No. 3, 2015, p. 548-555.Research output: Contribution to journal › Journal article › Research › peer-review
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Stability of glucagon-like peptide-1 and glucagon in human plasma. / Albrechtsen, Nicolai Jacob Wewer; Bak, Monika Judyta; Hartmann, Bolette; Christensen, Louise Wulff; Kuhre, Rune E; Deacon, Carolyn; Holst, Jens Juul.
In: Endocrine Connections, Vol. 4, No. 1, 16.01.2015, p. 50-57.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific inhibition of bile acid transport alters plasma lipids and GLP-1. / Rudling, Mats; Camilleri, Michael; Graffner, Hans; Holst, Jens Juul; Rikner, Leif.
In: B M C Cardiovascular Disorders, Vol. 15, 75, 2015, p. 1-8.Research output: Contribution to journal › Journal article › Research › peer-review
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Sensing of triacylglycerol in the gut : different mechanisms for fatty acids and 2-monoacylglycerol. / Kleberg, Karen; Jacobsen, Anne Katrine; Ferreira, Jozelia G; Windeløv, Johanne Agerlin; Rehfeld, Jens F; Holst, Jens Juul; de Araujo, Ivan E; Hansen, Harald S.
In: The Journal of Physiology, Vol. 593, No. 8, 16.01.2015, p. 2097-109.Research output: Contribution to journal › Journal article › Research › peer-review
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Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors. / Aaboe, K.; Akram, S.; Deacon, C. F.; Holst, J. J.; Madsbad, S.; Krarup, T.
In: Diabetes, Obesity and Metabolism, Vol. 17, No. 1, 01.2015, p. 74-81.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex : The ADDITION-PRO Study. Diabetes 2015;64:2513–2525. / Ferch, Kristine; Torekov, Signe S.; Vistisen, Dorte; Johansen, Nanna B; Witte, Daniel R; Jonsson, Anna; Pedersen, Oluf; Hansen, Torben; Lauritzen, Torsten; Sandbek, Annelli; Holst, Jens Juul; Jørgensen, Marit E.
In: Diabetes, Vol. 64, No. 9, 01.09.2015, p. e30-e31.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women. / Gentile, Christopher L; Ward, Emery; Holst, Jens Juul; Astrup, Arne; Ormsbee, Michael J; Connelly, Scott; Arciero, Paul J.
In: Nutrition Journal, Vol. 14, 113, 2015.Research output: Contribution to journal › Journal article › Research › peer-review
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Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men. / Asmar, Ali; Simonsen, Lene; Asmar, Meena; Madsbad, Sten; Holst, Jens Juul; Frandsen, Erik; Moro, Cedric; Jonassen, Thomas; Bülow, Jens.
In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 308, No. 8, 15.04.2015, p. E641-E649.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance. / Eriksen, Marie; Jensen, David H; Tribler, Siri; Holst, Jens Juul; Madsbad, Sten; Krarup, Thure.
In: Diabetologia, Vol. 58, No. 5, 2015, p. 920-8.Research output: Contribution to journal › Journal article › Research › peer-review
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Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery. / Lund, Michael Taulo; Hansen, Merethe; Skaaby, Stinna; Dalby, Sina; Støckel, Mikael; Floyd, Andrea Karen; Bech, Karsten; Helge, Jørn Wulff; Holst, Jens Juul; Dela, Flemming.
In: The Journal of Physiology, Vol. 593, No. 14, 13.04.2015, p. 3123-33.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young. / Østoft, Signe Harring; Bagger, Jonatan Ising; Hansen, Torben; Hartmann, Bolette; Pedersen, Oluf; Holst, Jens Juul; Knop, Filip Krag; Vilsbøll, Tina.
In: European Journal of Endocrinology, Vol. 173, No. 2, 01.08.2015, p. 205-215.Research output: Contribution to journal › Journal article › Research › peer-review
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Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs. / Barkholt, Pernille; Vegge, Andreas; Clausen, Trine Ryberg; Birck, Malene Muusfeldt; Fels, Johannes Josef; Støckel, Mikael; Gögenür, Ismayil; Eriksen, Thomas; Holst, Jens Juul; Hansen, Axel Kornerup; Thymann, Thomas; Jelsing, Jacob; Sangild, Per Torp; Raun, Kirsten.
In: Journal of Obesity and Bariatrics, Vol. 1, No. 1, 2015.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with psoriasis are insulin resistant. / Gyldenløve, Mette; Storgaard, Heidi; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K; Skov, Lone.
In: Journal of the American Academy of Dermatology, Vol. 72, No. 4, 04.2015, p. 599-605.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation. / Veedfald, Simon; Plamboeck, Astrid; Hartmann, Bolette; Svendsen, Lars B; Vilsbøll, Tina; Knop, Filip K; Holst, Jens J.
In: Peptides, Vol. 71, 09.2015, p. 229-31.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine. / Kuhre, Rune E.; Frost, Charlotte R.; Svendsen, Berit; Holst, Jens Juul.
In: Diabetes, Vol. 64, No. 2, 02.2015, p. 370-382.Research output: Contribution to journal › Journal article › Research › peer-review
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Measurement of the incretin hormones : glucagon-like peptide-1 and glucose-dependent insulinotropic peptide. / Kuhre, Rune Ehrenreich; Wewer Albrechtsen, Nicolai Jacob; Hartmann, Bolette; Deacon, Carolyn F.; Holst, Jens Juul.
In: Journal of Diabetes and its Complications, Vol. 29, No. 3, 04.2015, p. 445-450.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide for Type 2 diabetes and obesity : a 2015 update. / Iepsen, Eva Pers Winning; Torekov, Signe Sørensen; Holst, Jens Juul.
In: Expert Review of Cardiovascular Therapy, Vol. 13, No. 7, 2015, p. 753-67.Research output: Contribution to journal › Journal article › Research › peer-review
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L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients. / Samocha-Bonet, Dorit; Chisholm, Don J; Holst, Jens Juul; Greenfield, Jerry R.
In: Nutrients, Vol. 7, No. 4, 2015, p. 2101-8.Research output: Contribution to journal › Journal article › Research › peer-review
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Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans : A Proof of Concept. / Simon, Marie-Christine; Strassburger, Klaus; Nowotny, Bettina; Kolb, Hubert; Nowotny, Peter; Burkart, Volker; Zivehe, Fariba; Hwang, Jong-Hee; Stehle, Peter; Pacini, Giovanni; Hartmann, Bolette; Holst, Jens J; MacKenzie, Colin; Bindels, Laure B; Martinez, Ines; Walter, Jens; Henrich, Birgit; Schloot, Nanette C; Roden, Michael.
In: Diabetes Care, Vol. 38, No. 10, 2015, p. 1827-34.Research output: Contribution to journal › Journal article › Research › peer-review
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Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes. / Sejling, Anne-Sophie; Lange, Kai H W; Frandsen, Christian S; Diemar, Sarah S; Tarnow, Lise; Faber, Jens; Holst, Jens J; Hartmann, Bolette; Hilsted, Linda; Kjaer, Troels W; Juhl, Claus B; Thorsteinsson, Birger; Pedersen-Bjergaard, Ulrik.
In: Diabetologia, Vol. 58, 2015, p. 1898–1906.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of gastrointestinal factors on glucose metabolism in patients with cirrhosis. / Junker, Anders E; Gluud, Lise L; Holst, Jens Juul; Knop, Filip K; Vilsbøll, Tina.
In: Journal of Gastroenterology and Hepatology, Vol. 30, No. 10, 10.2015, p. 1522-8.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin effect after oral amino Acid ingestion in humans. / Lindgren, Ola; Pacini, Giovanni; Tura, Andrea; Holst, Jens Juul; Deacon, Carolyn F; Ahrén, Bo.
In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 3, 03.2015, p. 1172-6.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy. / Kelstrup, Louise; Clausen, Tine D; Mathiesen, Elisabeth R; Hansen, Torben; Holst, Jens Juul; Damm, Peter.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 100, No. 5, 2015, p. 1967-75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition. / Rosenkilde Larsen, Mads; Morville, Thomas; Riis Andersen, Peter; Kjær, Katja; Rasmusen, Hanne; Holst, Jens Juul; Dela, Flemming; Westerterp, Klaas; Sjödin, Anders Mikael; Helge, Jørn Wulff.
In: American Journal of Clinical Nutrition, Vol. 102, No. 6, 2015, p. 1398-1405.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo efficacy of HD0471953 : A novel GPR119 agonist for the treatment of type 2 diabetes mellitus. / 'T Hart, L. M.; Fritsche, A.; Nijpels, G.; Van Leeuwen, N.; Donnelly, L. A.; Dekker, J. M.; Alssema, M.; Fadista, J.; Carlotti, F.; Gjesing, A. P.; Palmer, C. N.; Van Haeften, T. W.; Herzberg-Schäfer, S. A.; Simonis-Bik, A. M.; Houwing-Duistermaat, J. J.; Helmer, Q.; Deelen, J.; Guigas, B.; Hansen, T.; MacHicao, F.; Willemsen, G.; Heine, R. J.; Kramer, M. H.; Holst, J. J.; De Koning, E. J.; Häring, H. U.; Pedersen, O.; Groop, L.; De Geus, E. J.; Slagboom, P. E.; Boomsma, D. I.; Eekhoff, E. M.; Pearson, E. R.; Diamant, M.
In: Diabetes Technology & Therapeutics, Vol. 17, 01.02.2015, p. S131-S133.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations. / Jørgensen, Nils B; Dirksen, Carsten; Bojsen-Møller, Kirstine N; Kristiansen, Viggo B; Wulff, Birgitte S; Rainteau, Dominique; Humbert, Lydie; Rehfeld, Jens F; Holst, Jens Juul; Madsbad, Sten; Clausen, Trine R.
In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 3, 03.2015, p. E396-406.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Important species differences regarding lymph contribution to gut hormone responses. / Hansen, Marie; Hjøllund, Karina R; Hartmann, Bolette; Plamboeck, Astrid; Deacon, Carolyn F; Albrechtsen, Nicolai Jacob Wewer; Holst, Jens J.
In: Peptides, Vol. 71, 09.2015, p. 28-31.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin effect is an early sign of glucose dysmetabolism in nondiabetic patients with psoriasis. / Gyldenløve, M; Lauritsen, Tina Vilsbøll; Zachariae, Claus; Holst, J J; Knop, F K; Skov, Lone.
In: Journal of Internal Medicine, Vol. 278, No. 6, 11.11.2015, p. 660-70.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass. / Martinussen, Christoffer; Bojsen-Moller, Kirstine N; Dirksen, Carsten; Jacobsen, Siv H; Jørgensen, Nils B; Kristiansen, Viggo B; Holst, Jens Juul; Madsbad, Sten.
In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 308, No. 6, 15.03.2015, p. E535-44.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoglycemia-associated changes in the electroencephalogram in patients with type 1 diabetes and normal hypoglycemia awareness or unawareness. / Sejling, Anne-Sophie; Kjær, Troels W; Pedersen-Bjergaard, Ulrik; Diemar, Sarah S; Frandsen, Christian S S; Hilsted, Linda; Faber, Jens; Holst, Jens Juul; Tarnow, Lise; Nielsen, Martin N; Remvig, Line S; Thorsteinsson, Birger; Juhl, Claus B.
In: Diabetes, Vol. 64, No. 5, 05.2015, p. 1760-9.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides. / Challis, Benjamin G; Albrechtsen, Nicolai J Wewer; Bansiya, Vishakha; Burling, Keith; Barker, Peter; Hartmann, Bolette; Gribble, Fiona; O'Rahilly, Stephen; Holst, Jens J; Simpson, Helen L.
In: Endocrinology, Diabetes & Metabolism Case Reports, Vol. 2015, 150105, 2015, p. 1-7.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes. / Christensen, Mikkel; Calanna, Salvatore; Sparre-Ulrich, Alexander H; Kristensen, Peter L; Rosenkilde, Mette M; Faber, Jens; Purrello, Francesco; van Hall, Gerrit; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K.
In: Diabetes, Vol. 64, No. 1, 01.2015, p. 72-78.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx. / Kuhre, Rune Ehrenreich; Bechmann, Louise Ellegaard; Hartmann, Bolette; Albrechtsen, Nicolai Jacob Wewer; Holst, Jens Juul.
In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 308, No. 12, 21.04.2015, p. E1123–E1130.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex : The ADDITION-PRO Study. / Færch, Kristine; Torekov, Signe S; Vistisen, Dorte; Johansen, Nanna B; Witte, Daniel R; Jonsson, Anna; Pedersen, Oluf; Hansen, Torben; Lauritzen, Torsten; Sandbæk, Annelli; Holst, Jens Juul; Jørgensen, Marit E.
In: Diabetes, Vol. 64, 07.2015, p. 2513-25.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying and disease activity in inflammatory bowel disease. / Keller, Jutta; Binnewies, Ulrich; Rösch, Marie; Juul Holst, Jens; Beglinger, Christoph; Andresen, Viola; Layer, Peter.
In: European Journal of Clinical Investigation, Vol. 45, No. 12, 2015, p. 1234-42.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels. / Hofsø, Dag; Birkeland, Kåre I; Holst, Jens J; Bollerslev, Jens; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran.
In: Diabetology & Metabolic Syndrome, Vol. 7, 69, 2015, p. 1-4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass. / Guimarães, Marta; Rodrigues, Pedro; Pereira, Sofia S; Nora, Mário; Gonçalves, Gil; Albrechtsen, Nicolai Wewer; Hartmann, Bolette; Holst, Jens Juul; Monteiro, Mariana P.
In: Endocrinology, Diabetes & Metabolism Case Reports, Vol. 2015, 150049, 2015, p. 1-5.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women. / Iepsen, Eva Pers Winning; Lundgren, Julie Rehné; Hartmann, Bolette; Pedersen, Oluf; Hansen, Torben; Jørgensen, Niklas R; Jensen, Jens-Erik Beck; Holst, Jens J; Madsbad, Sten; Torekov, Signe Sørensen.
In: The Journal of clinical endocrinology and metabolism, Vol. 100, No. 8, 2015, p. 2909 –2917.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 defects in diabetes. / Janus, Charlotte; Albrechtsen, Nicolai Jacob Wewer; Holst, Jens Juul.
2015, .Research output: Other contribution › Net publication - Internet publication › Research › peer-review
- Published
Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults. / Bjerg, Anne Toksvig; Kristensen, Mette Bredal; Ritz, Christian; Stark, K D; Holst, Jens Juul; Leser, Thomas Dyrmann; Wellejus, Anja; Astrup, Arne.
In: Beneficial Microbes, Vol. 6, No. 1, 2015, p. 29-39.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes. / Ten Kulve, Jennifer S; Veltman, Dick J; van Bloemendaal, Liselotte; Barkhof, Frederik; Deacon, Carolyn F; Holst, Jens J; Konrad, Robert J; Sloan, John H; Drent, Madeleine L; Diamant, Michaela; IJzerman, Richard G.
In: Diabetologia, Vol. 58, No. 12, 12.2015, p. 2688-98.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study : The Lira-1 study. / Dejgaard, Thomas Fremming; Knop, Filip Krag; Tarnow, Lise; Frandsen, Christian Seerup; Hansen, Tanja Stenbæk; Almdal, Thomas; Holst, Jens Juul; Madsbad, Sten; Andersen, Henrik Ullits.
In: B M J Open, Vol. 5, No. 4, e007791, 2015, p. 1-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes : a randomized double blind placebo-controlled cross-over study. / Schopman, J E; Hoekstra, J B L; Frier, B M; Ackermans, M T; de Sonnaville, J J J; Stades, A M; Zwertbroek, R; Hartmann, B; Holst, Jens Juul; Knop, F K; Holleman, F.
In: Diabetes, Obesity and Metabolism, Vol. 17, No. 6, 06.2015, p. 546-53.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of insulin therapy on weight gain and fat distribution in the HF/HS-STZ rat model of type 2 diabetes. / Skovsø, S.; Damgaard, J; Fels, J J; Olsen, G S; Wolf, X A; Rolin, B; Holst, J J.
In: International Journal of Obesity, Vol. 39, No. 10, 2015, p. 1531-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of angiotensin II receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes. / Færch, Louise H; Thorsteinsson, Birger; Tarnow, Lise; Holst, Jens Juul; Kjær, Troels Wesenberg; Kanters, Jørgen; Larroude, Charlotte; Dela, Flemming; Pedersen-Bjergaard, Ulrik.
In: Journal of the Renin-Angiotensin-Aldosterone System, Vol. 16, No. 4, 12.2015, p. 1036-1045.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes. / Knudsen, Sine H; Karstoft, Kristian; Winding, Kamilla; Holst, Jens J; Pedersen, Bente K; Solomon, Thomas.
In: Diabetes, Obesity and Metabolism, Vol. 17, No. 2, 02.2015, p. 207-210.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effect of moderate- and high-intensity acute exercise on appetite in obese individuals. / Martins, Catia; Stensvold, Dorthe; Finlayson, Graham; Holst, Jens Juul; Wisloff, Ulrik; Kulseng, Bård; Morgan, Linda; King, Neil A.
In: Medicine and Science in Sports and Exercise, Vol. 47, No. 1, 01.2015, p. 40-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes. / Rhee, Nicolai A; Wahlgren, Camilla D; Pedersen, Jens; Mortensen, Brynjulf; Langholz, Ebbe; Wandall, Erik P; Friis, Steffen U; Vilmann, Peter; Paulsen, Sarah J; Kristiansen, Viggo B; Jelsing, Jacob; Dalbøge, Louise S; Poulsen, Steen S; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K.
In: Diabetologia, Vol. 58, No. 10, 2015, p. 2254-2258.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure. / Bagger, Jonatan I; Holst, Jens J; Hartmann, Bolette; Andersen, Birgitte; Knop, Filip K; Vilsbøll, Tina.
In: The Journal of Clinical Endocrinology & Metabolism, Vol. 100, No. 12, 2015, p. 4541–4552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism. / Mikkelsen, Kristian H; Frost, Morten; Bahl, Martin I; Licht, Tine R; Jensen, Ulrich S; Rosenberg, Jacob; Pedersen, Oluf; Hansen, Torben; Rehfeld, Jens F; Holst, Jens J; Vilsbøll, Tina; Knop, Filip K.
In: PLOS ONE, Vol. 10, No. 11, e0142352, 12.11.2015, p. 1-14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients. / Yabe, Daisuke; Kuroe, Akira; Watanabe, Koin; Iwasaki, Masahiro; Hamasaki, Akihiro; Hamamoto, Yoshiyuki; Harada, Norio; Yamane, Shunsuke; Lee, Soushou; Murotani, Kenta; Deacon, Carolyn F; Holst, Jens Juul; Hirano, Tsutomu; Inagaki, Nobuya; Kurose, Takeshi; Seino, Yutaka.
In: Journal of Diabetes and its Complications, Vol. 29, 2015, p. 413-421.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs. / Shen, René Liang; Thymann, Thomas; Østergaard, Mette Viberg; Støy, Ann Cathrine Findal; Krych, Lukasz; Nielsen, Dennis Sandris; Lauridsen, Charlotte; Hartmann, Bolette; Holst, Jens Juul; Burrin, Douglas G.; Sangild, Per Torp.
In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 309, No. 5, 2015, p. G310-G323.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes. / Reiband, H K; Schmidt, S; Ranjan, Ajenthen; Holst, Jens Juul; Madsbad, S; Nørgaard, K.
In: Diabetes - Metabolism: Research and Reviews (Print Edition), Vol. 31, No. 7, 2015, p. 672-9.Research output: Contribution to journal › Review › Research › peer-review
- Published
Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance. / Sjøberg, Kim Anker; Rattigan, Stephen; Jeppesen, Jacob Fuglsbjerg; Lundsgaard, Annemarie; Holst, Jens Juul; Kiens, Bente.
In: Journal of Physiology, Vol. 593, No. 9, 2015, p. 2185-2198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth) : a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study. / Bohl, Mette; Bjørnshave, Ann; Rasmussen, Kia V; Schioldan, Anne Grethe; Amer, Bashar; Larsen, Mette K; Dalsgaard, Trine K; Holst, Jens Juul; Herrmann, Annkatrin; O'Neill, Sadhbh; O'Driscoll, Lorraine; Afman, Lydia; Jensen, Erik; Christensen, Merete M; Gregersen, Søren; Hermansen, Kjeld.
In: The American Journal of Clinical Nutrition, Vol. 101, No. 4, 04.2015, p. 870-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists. / Hansen, L. S.; Sparre-Ulrich, A. H.; Svendsen, B.; Christensen, M.; Hartmann, B.; Knop, F. K.; Holst, J. J.; Rosenkilde, M. M.
In: Diabetologia, Vol. 58, No. 1 supplement, 569, 09.2015, p. S276-S277.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients. / Jørgensen, Morten B; Idorn, Thomas; Knop, Filip K; Holst, Jens Juul; Hornum, Mads; Feldt-Rasmussen, Bo.
In: Nephrology, Dialysis, Transplantation, Vol. 30, No. 3, 03.2015, p. 513-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals. / Haahr, M. E.; Hansen, D. L.; Fisher, P. M.; Svarer, C.; Stenbæk, D. S.; Madsen, K.; Madsen, J.; Holst, J. J.; Baaré, W. F. C.; Hojgaard, L.; Almdal, T.; Knudsen, G. M.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, No. 14, 08.04.2015, p. 5884-5889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile acid mediated effects on gut integrity and performance of early-weaned piglets. / de Diego-Cabero, Nuria; Mereu, Alessandro; Menoyo, David; Holst, Jens Juul; Ipharraguerre, Ignacio R.
In: B M C Veterinary Research, Vol. 11, No. 1, 111, 2015, p. 1-8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors. / Brighton, Cheryl A.; Rievaj, Juraj; Kuhre, Rune E.; Glass, Leslie L.; Schoonjans, Kristina; Holst, Jens J.; Gribble, Fiona M.; Reimann, Frank.
In: Endocrinology, Vol. 156, No. 11, 2015, p. 3961-1370.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine. / Svendsen, Berit; Pedersen, Jens; Albrechtsen, Nicolai Jacob Wewer; Hartmann, Bolette; Toräng, Signe; Rehfeld, Jens F; Seier Poulsen, Steen; Holst, Jens Juul.
In: Endocrinology, Vol. 156, No. 3, en20141710, 03.2015, p. 847-857.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow. / Jensen, Elisa Pouline; Poulsen, Steen Seier; Kissow, Hannelouise; Holstein-Rathlou, Niels-Henrik; Deacon, Carolyn F.; Jensen, Boye L.; Holst, Jens J.; Sorensen, Charlotte M.
In: A J P: Renal Physiology (Online), Vol. 308, No. 8, 15.04.2015, p. F867-F877.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accelerated protein digestion and amino acid absorption after Roux-en-Y gastric bypass. / Bojsen-Møller, Anna Kirstine; Jacobsen, Siv H; Dirksen, Carsten; Jørgensen, Nils B; Reitelseder, Søren; Jensen, Jens-Erik B; Kristiansen, Viggo B; Holst, Jens J; van Hall, Gerrit; Madsbad, Sten.
In: The American Journal of Clinical Nutrition, Vol. 102, No. 3, 09.2015, p. 600-7.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
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