Jens Juul Holst

Jens Juul Holst

Professor


  1. 2010
  2. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus. / Aaboe, K; Knop, F K; Vilsbøll, T; Deacon, C F; Holst, Jens Juul; Madsbad, S; Krarup, Troels Magelund.

    In: Diabetes, Obesity and Metabolism, Vol. 12, No. 4, 01.04.2010, p. 323-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest. / Alibegovic, Amra C; Sonne, Mette P; Højbjerre, Lise; Hansen, Torben; Pedersen, Oluf; van Hall, Gerrit; Holst, Jens J; Stallknecht, Bente; Dela, Flemming; Vaag, Allan.

    In: Diabetes, Vol. 59, No. 4, 2010, p. 836-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans? / Asmar, Meena; Bache, Michael; Knop, Filip K; Madsbad, Sten; Holst, Jens Juul.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 5, 01.05.2010, p. 2367-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances. / Asmar, Meena; Holst, Jens Juul.

    In: Current Opinion in Endocrinology, Diabetes and Obesity, Vol. 17, No. 1, 01.02.2010, p. 57-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans. / Asmar, Meena; Simonsen, Lene; Madsbad, Sten; Stallknecht, Bente Merete; Holst, Jens Juul; Bülow, Jens.

    In: Diabetes, Vol. 59, No. 9, 01.09.2010, p. 2160-3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans. / Asmar, Meena; Tangaa, Winnie; Madsbad, Sten; Hare, Kristine; Astrup, Arne; Flint, Anne; Bülow, Jens; Holst, Jens Juul.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 298, No. 3, 2010, p. E614-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. / Asmar, Meena; Højberg, Patricia V; Deacon, Carolyn F; Hare, Kristine; Holst, Jens Juul; Madsbad, Sten.

    In: Regulatory Peptides, Vol. 160, No. 1-3, 2010, p. 175-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes. / Asmar, Meena; Højberg, Patricia; Deacon, Carolyn F.; Hare, Kristine; Holst, Jens Juul; Madsbad, Sten.

    In: Regulatory Peptides, Vol. 160, No. 1-3, 2010, p. 175-180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose. / Bock, Gerlies; Man, Chiara Dalla; Micheletto, Francesco; Basu, Rita; Rn, Paula D Giesler; Laugen, Jeanette; Deacon, Carolyn F; Holst, Jens J; Toffolo, Gianna; Cobelli, Claudio; Rizza, Robert A; Vella, Adrian.

    In: Clinical Endocrinology, Vol. 73, 2010, p. 189-196.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects. / Brader, Lea Johanne; Holm, L.; Mortensen, L.; Thomsen, C.; Astrup, Arne; Holst, Jens Juul; Vrese, M. de; Schrezenmeir, J.; Hermansen, Kjeld.

    In: Nutrition, Metabolism & Cardiovascular Diseases, Vol. 20, No. 2, 2010, p. 101-109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters. / Bremholm, Lasse; Hornum, Mads; Andersen, Ulrik B; Holst, Jens Juul.

    In: Regulatory Peptides, Vol. 159, No. 1-3, 08.01.2010, p. 67-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men. / Carr, Richard D; Larsen, Marianne O; Jelic, Katarina; Lindgren, Ola; Vikman, Jenny; Holst, Jens J; Deacon, Carolyn F; Ahrén, Bo.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 95, No. 2, 2010, p. 872-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes. / Christensen, Mikkel; Knop, Filip K; Vilsbøll, Tina; Aaboe, Kasper; Holst, Jens Juul; Madsbad, Sten; Krarup, Thure.

    In: Regulatory Peptides, Vol. 163, No. 1-3, 09.08.2010, p. 96-101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes. / Deacon, Carolyn F; Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 19, No. 1, 01.2010, p. 133-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes. / Deacon, Carolyn F.; Holst, Jens Juul.

    In: Expert Opinion on Investigational Drugs, Vol. 19, No. 1, 2010, p. 133-140.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion : a case report. / Dirksen, Carsten; Hansen, Dorte L; Madsbad, Sten; Hvolris, Lisbeth E; Naver, Lars S; Holst, Jens Juul; Worm, Dorte.

    In: Diabetes Care, Vol. 33, No. 2, 02.2010, p. 375-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report. / Dirksen, Carsten; Hansen, Dorte L; Madsbad, Sten; Hvolris, Lisbeth E; Naver, Lars S; Holst, Jens J; Worm, Dorte; Dirksen, Carsten; Hansen, Dorte L; Madsbad, Sten; Hvolris, Lisbeth E; Naver, Lars S; Holst, Jens J; Worm, Dorte.

    In: Diabetes Care, Vol. 33, No. 2, 2010, p. 375-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis. / Edholm, T; Degerblad, M; Grybäck, P; Hilsted, L; Holst, Jens Juul; Jacobsson, H; Efendic, S; Schmidt, P T; Hellström, P M.

    In: Neurogastroenterology and Motility Online, Vol. 22, No. 11, 01.11.2010, p. 1191-200, e315.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans. / Falkén, Y; Hellström, P M; Sanger, G J; Dewit, O; Dukes, G; Grybäck, P; Holst, Jens Juul; Näslund, E.

    In: Neurogastroenterology and Motility, Vol. 22, No. 6, 01.06.2010, p. e192-200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure. / Halbirk, Mads; Nørrelund, Helene; Møller, Niels; Holst, Jens Juul; Schmitz, Ole; Nielsen, Bent Roni Ranghøj; Nielsen-Kudsk, Jens Erik; Nielsen, Søren Steen; Nielsen, Torsten Toftegaard; Eiskjaer, Hans; Bøtker, Hans Erik; Wiggers, Henrik.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 298, No. 3, 01.03.2010, p. H1096-H1102.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Treatment of insulin resistance and obesity by stimulating GLP-1 release. / Hansen, Harald S. (Inventor); Diep, Thi Ai (Inventor); Holst, Jens Juul (Inventor); Rosenkilde, Mette Marie (Inventor); Andersen, Niels Wellner (Inventor).

    IPC No.: A61K 31/23. Patent No.: PCT/DK2010/050161. Jun 24, 2010.

    Research output: Patent

  24. Published

    Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects. / Hansen, K B; Vilsbøll, T; Bagger, J I; Holst, Jens Juul; Knop, F K.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 7, 01.07.2010, p. 3309-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes. / Hare, Kristine J; Vilsbøll, Tina; Holst, Jens Juul; Knop, Filip K.

    In: American Journal of Physiology: Endocrinology and Metabolism, Vol. 298, No. 4, 01.04.2010, p. E832-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action. / Hare, Kristine J; Vilsbøll, Tina; Asmar, Meena; Deacon, Carolyn F; Knop, Filip K; Holst, Jens Juul.

    In: Diabetes, Vol. 59, No. 7, 01.07.2010, p. 1765-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

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