Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Antihyperglycemic effects of stevioside in type 2 diabetic subjects. / Gregersen, Søren; Jeppesen, Per B; Holst, Jens Juul; Hermansen, Kjeld.

    In: Metabolism, Vol. 53, No. 1, 01.2004, p. 73-6.

    Research output: Contribution to journalJournal article

  2. Published

    Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling. / Gromada, J; Bokvist, K; Ding, W G; Holst, J J; Nielsen, Jens Høiriis; Rorsman, P.

    In: Diabetes, Vol. 47, No. 1, 1998, p. 57-65.

    Research output: Contribution to journalJournal article

  3. Published

    Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism. / Grunddal, Kaare Villum; Ratner, Cecilia F; Svendsen, Berit; Sommer, Felix; Engelstoft, Maja S; Madsen, Andreas N; Pedersen, Jens; Nøhr, Mark K; Egerod, Kristoffer L; Nawrocki, Andrea R; Kowalski, Timothy; Howard, Andrew D; Poulsen, Steen Seier; Offermanns, Stefan; Bäckhed, Gert Fredrik; Holst, Jens J; Holst, Birgitte; Schwartz, Thue W.

    In: Endocrinology, Vol. 157, No. 1, en20151600, 01.2016, p. 176-94.

    Research output: Contribution to journalJournal article

  4. Published

    Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers. / Grøndahl, Magnus F.; Bagger, Jonatan I.; Lund, Asger; Faurschou, Annesofie; Rehfeld, Jens F.; Holst, Jens J.; Vilsbøll, Tina; Knop, Filip K.

    In: Diabetes Care, Vol. 41, No. 6, 06.2018, p. 1260-1267.

    Research output: Contribution to journalJournal article

  5. Published

    GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets. / Guan, X.; Stoll, B.; Lu, X.; Tappenden, K.; Holst, Jens Juul; Hartmann, Bolette; Burrin, D.G.

    In: Today in Medicine. Gastroenterology, No. 125, 2003, p. 136-147.

    Research output: Contribution to journalJournal article

  6. Published

    GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. / Guan, X.F.; Karpen, H.E.; Stephens, J.; Bukowski, J.T.; Niu, S.Y.; Zhang, G.C.; Stoll, B.; Finegold, M.J.; Holst, J.J.; Hadsell, D.L.; Nichols, B.L.; Burrin, D.G.

    In: Today in Medicine. Gastroenterology, Vol. 130, No. 1, 2006, p. 150-164.

    Research output: Contribution to journalJournal article

  7. Published

    GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1. / Guan, Xinfu; Stoll, Barbara; Lu, Xiaofeng; Tappenden, Kelly A; Holst, Jens Juul; Hartmann, Bolette; Burrin, Douglas G.

    In: Gastroenterology, Vol. 125, No. 1, 07.2003, p. 136-47.

    Research output: Contribution to journalJournal article

  8. Published

    GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. / Guan, Xinfu; Karpen, Heidi E; Stephens, John; Bukowski, John T; Niu, Sanyong; Zhang, Guangcheng; Stoll, Barbara; Finegold, Milton J; Holst, Jens Juul; Hadsell, Darryl; Hadsell, Darry L; Nichols, Buford L; Burrin, Douglas G.

    In: Gastroenterology, Vol. 130, No. 1, 01.2006, p. 150-64.

    Research output: Contribution to journalJournal article

  9. Published

    GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass. / Guimarães, Marta; Rodrigues, Pedro; Pereira, Sofia S; Nora, Mário; Gonçalves, Gil; Albrechtsen, Nicolai Wewer; Hartmann, Bolette; Holst, Jens Juul; Monteiro, Mariana P.

    In: Endocrinology, Diabetes & Metabolism Case Reports, Vol. 2015, 150049, 2015, p. 1-5.

    Research output: Contribution to journalJournal article

  10. Published

    Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery. / Guldstrand, M; Ahrén, B; Näslund, E; Holst, Jens Juul; Adamson, U.

    In: Diabetes, Obesity and Metabolism, Vol. 11, No. 11, 2009, p. 1027-33.

    Research output: Contribution to journalJournal article

  11. Published

    The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk. / Gunnerud, Ulrika; Holst, Jens Juul; Östman, Elin; Björck, Inger.

    In: Nutrition Journal, Vol. 11, 2012, p. 83.

    Research output: Contribution to journalJournal article

  12. Published

    Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal. / Gunnerud, Ulrika J; Heinzle, Cornelia; Holst, Jens Juul; Östman, Elin M; Björck, Inger M E.

    In: P L o S One, Vol. 7, No. 9, 2012, p. e44731.

    Research output: Contribution to journalJournal article

  13. Published

    Subcutaneous injection of glucagon-like insulintropic peptide reduces postprandial glycemia in non-insulin dependent diabetes. / Gutniak, M.K.; Linde, B.; Holst, Jens Juul; Efendic, S.

    In: Diabetes Care, No. 17, 1994, p. 1039-1044.

    Research output: Contribution to journalJournal article

  14. Published

    Antidiabetogenic action of glucagon-like peptide- 1 related to administration relative to meal intake in subjects with type 2 diabetes. / Gutniak, M.K.; Svartberg, J.; Hellstrom, P.M.; Holst, J.J.

    In: J Intern Med, No. 250, 2001, p. 81-87.

    Research output: Contribution to journalJournal article

  15. Published

    Antidiabetogenic Effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus. / Gutniak, Mark; Ørskov, Cathrine; Holst, Jens Juul; Ahrén, Bo; Efendic, Suad.

    In: New England Journal of Medicine, No. 326, 1992, p. 1316-1322.

    Research output: Contribution to journalJournal article

  16. Published

    Impaired incretin effect is an early sign of glucose dysmetabolism in nondiabetic patients with psoriasis. / Gyldenløve, M; Lauritsen, Tina Vilsbøll; Zachariae, Claus; Holst, J J; Knop, F K; Skov, Lone.

    In: Journal of Internal Medicine, Vol. 278, No. 6, 11.11.2015, p. 660-70.

    Research output: Contribution to journalJournal article

  17. Published

    Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis. / Gyldenløve, M; Lauritsen, Tina Vilsbøll; Holst, Jens Juul; Zachariae, C; Skov, L; Knop, F K.

    In: British Journal of Dermatology, Vol. 175, No. 5, 11.2016, p. 1085–1088.

    Research output: Contribution to journalLetter

  18. Published

    Patients with psoriasis are insulin resistant. / Gyldenløve, Mette; Storgaard, Heidi; Holst, Jens Juul; Vilsbøll, Tina; Knop, Filip K; Skov, Lone.

    In: Journal of the American Academy of Dermatology, Vol. 72, No. 4, 04.2015, p. 599-605.

    Research output: Contribution to journalJournal article

  19. Published

    Effect of method of delivery of sodium butyrate on rumen development in newborn calves. / Górka, P; Kowalski, Z M; Pietrzak, P; Kotunia, A; Jagusiak, W; Holst, Jens Juul; Guilloteau, P; Zabielski, R.

    In: Journal of Dairy Science, Vol. 94, No. 11, 11.2011, p. 5578-88.

    Research output: Contribution to journalJournal article

  20. Published

    Glucagon-like peptide 1: on its way to clinical application. / Göke, B.; Göke, R.; Holst, Jens Juul; Ørskov, Cathrine.

    In: Digestion, No. 54, 1994, p. 339-340.

    Research output: Contribution to journalJournal article

  21. Published

    Role of Gastrin‐Releasing Peptide in Vagal Control of Gastrin Secretion. / HOLST, J. J.; KNUHTSEN, S.; ØRSKOV, C.; SKAK‐NIELSEN, T.; POULSEN, S. S.; NIELSEN, O. VAGN.

    In: Annals of the New York Academy of Sciences, Vol. 547, No. 1, 01.01.1988, p. 514-515.

    Research output: Contribution to journalJournal article

  22. Published

    Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals. / Haahr, M. E.; Hansen, D. L.; Fisher, P. M.; Svarer, C.; Stenbæk, D. S.; Madsen, K.; Madsen, J.; Holst, J. J.; Baaré, W. F. C.; Hojgaard, L.; Almdal, T.; Knudsen, G. M.

    In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, No. 14, 08.04.2015, p. 5884-5889.

    Research output: Contribution to journalJournal article

  23. Published

    Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon. / Haderslev, K V; Jeppesen, P B; Hartmann, B; Thulesen, J; Sorensen, H A; Graff, J; Tofteng, F; Poulsen, S S; Madsen, J L; Holst, J J; Staun, M; Mortensen, P B; Poulsen, Steen Seier.

    In: Scandinavian Journal of Gastroenterology, Vol. 37, No. 4, 01.04.2002, p. 392-8.

    Research output: Contribution to journalJournal article

  24. Published

    Short-term administration of Glucagon-like peptide-2. Effects on bone mass density and markers of bone remodelling in short bowel patients with no colon. / Haderslev, K.V.; Jeppesen, P.B.; Hartmann, B.; Thulesen, Jesper; Sørensen, H.A.; Graff, J.; Hansen, B.S.; Tofteng, F.; Poulsen, Steen Seier; Madsen, J.L.; Holst, J.J.; Staun, M.; Mortensen, P.B.

    In: Scandinavian Journal of Gastroenterology, No. vol. 37, 2002, p. 392-398.

    Research output: Contribution to journalJournal article

  25. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition. / Haedersdal, S.; Lund, A.; Maagensen, H.; Nielsen-Hannerup, E.; Holst, J.; Knop, F.; Vilsboll, T.

    2018. S312-S312.

    Research output: Contribution to conferencePosterResearch

  26. Published

    Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion. / Hagemann, D.; Holst, J.J.; Gethmann, A.; Banasch, M.; Schmidt, W.E.; Meier, J.J.

    In: Regulatory Peptides, Vol. 143, No. 1-3, 2007, p. 64-68.

    Research output: Contribution to journalJournal article

  27. Published

    Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion. / Hagemann, Dirk; Holst, Jens Juul; Gethmann, Arnica; Banasch, Matthias; Schmidt, Wolfgang E; Meier, Juris J.

    In: Regulatory Peptides, Vol. 143, No. 1-3, 04.10.2007, p. 64-8.

    Research output: Contribution to journalJournal article

  28. Published

    Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure. / Halbirk, Mads; Nørrelund, Helene; Møller, Niels; Holst, Jens Juul; Schmitz, Ole; Nielsen, Bent Roni Ranghøj; Nielsen-Kudsk, Jens Erik; Nielsen, Søren Steen; Nielsen, Torsten Toftegaard; Eiskjaer, Hans; Bøtker, Hans Erik; Wiggers, Henrik.

    In: American Journal of Physiology: Heart and Circulatory Physiology, Vol. 298, No. 3, 01.03.2010, p. H1096-H1102.

    Research output: Contribution to journalJournal article

  29. Published

    GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes. / Halden, Thea A S; Egeland, Erlend J; Åsberg, Anders; Hartmann, Anders; Midtvedt, Karsten; Khiabani, Hassan Z; Holst, Jens J; Knop, Filip K; Hornum, Mads; Feldt-Rasmussen, Bo; Jenssen, Trond.

    In: Diabetes Care, Vol. 39, 23.02.2016, p. 617-24.

    Research output: Contribution to journalJournal article

  30. Published

    Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans. / Halim, Md. Abdul; Degerblad, Marie; Sundbom, Magnus; Karlbom, Urban; Holst, Jens Juul; Webb, Dominic-Luc; Hellstrom, Per M.

    In: Journal of Clinical Endocrinology & Metabolism, Vol. 103, No. 2, 2018, p. 575-585.

    Research output: Contribution to journalJournal article

  31. Published

    Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus. / Hannibal, J.; Mikkelsen, J.D.; Clausen, H.; Holst, Jens Juul; Wulff, B.S.; Fahrenkrug, Jan.

    In: Regulatory Peptides, No. 55, 1995, p. 133-148.

    Research output: Contribution to journalJournal article

  32. Published

    Et nyopdaget fotopigment i retina, melanopsin, styrer hjernens biologiske ur. / Hannibal, Jens; Fahrenkrug, Jan; Holst, Jens Juul.

    In: Ugeskrift for læger, Vol. 164, No. 19, 2002, p. 2523.

    Research output: Contribution to journalJournal article

  33. Published

    Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia? / Hansen, A M K; Bödvarsdottir, T B; Nordestgaard, D N E; Heller, R S; Gotfredsen, C F; Maedler, K; Fels, JJ; Holst, Jens Juul; Karlsen, AE.

    In: Diabetologia, Vol. 54, No. 6, 2011, p. 1379-87.

    Research output: Contribution to journalJournal article

  34. Published

    Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs. / Hansen, Carl Frederik; Thymann, Thomas; Andersen, Anders Daniel; Holst, Jens Juul; Hartmann, Bolette; Hilsted, Linda; Langhorn, Louise; Jelsing, Jacob; Sangild, Per T.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 310, No. 8, 28.01.2016, p. G550-560.

    Research output: Contribution to journalJournal article

  35. Published

    Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes. / Hansen, Christian Stevns; Frandsen, Christian Seerup; Fleischer, Jesper; Vistisen, Dorte; Holst, Jens Juul; Tarnow, Lise; Knop, Filip Krag; Madsbad, Sten; Andersen, Henrik Ullits; Dejgaard, Thomas Fremming.

    In: Frontiers in Endocrinology, Vol. 10, 242, 2019.

    Research output: Contribution to journalJournal article

  36. Published

    GPR119 as a fat sensor. / Hansen, Harald S; Rosenkilde, Mette M; Holst, Jens Juul; Schwartz, Thue W.

    In: Trends in Pharmacological Sciences, Vol. 33, No. 7, 07.2012, p. 374-81.

    Research output: Contribution to journalJournal article

  37. Published

    Treatment of insulin resistance and obesity by stimulating GLP-1 release. / Hansen, Harald S. (Inventor); Diep, Thi Ai (Inventor); Holst, Jens Juul (Inventor); Rosenkilde, Mette Marie (Inventor); Andersen, Niels Wellner (Inventor).

    IPC No.: A61K 31/23. Patent No.: PCT/DK2010/050161. Jun 24, 2010.

    Research output: Patent

  38. Published

    Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists. / Hansen, K B; Knop, F K; Holst, Jens Juul; Vilsbøll, T.

    In: International Journal of Clinical Practice, Vol. 63, No. 8, 2009, p. 1154-60.

    Research output: Contribution to journalJournal article

  39. Published

    Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects. / Hansen, K B; Vilsbøll, T; Bagger, J I; Holst, Jens Juul; Knop, F K.

    In: The Journal of clinical endocrinology and metabolism, Vol. 95, No. 7, 01.07.2010, p. 3309-17.

    Research output: Contribution to journalJournal article

  40. Published

    Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 2, 2011, p. 447-53.

    Research output: Contribution to journalJournal article

  41. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. / Hansen, Katrine B; Rosenkilde, Mette M; Knop, Filip K; Wellner, Niels; Diep, Thi A; Rehfeld, Jens F; Andersen, Ulrik B; Holst, Jens J; Hansen, Harald S.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 96, No. 9, 2011, p. E1409-17.

    Research output: Contribution to journalJournal article

  42. Published

    Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects. / Hansen, Katrine B; Vilsbøll, Tina; Bagger, Jonatan I; Holst, Jens Juul; Knop, Filip K.

    In: Journal of Clinical Endocrinology and Metabolism, Vol. 97, No. 4, 2012, p. 1363-70.

    Research output: Contribution to journalJournal article

  43. Published
  44. Published

    N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor. / Hansen, L S; Sparre-Ulrich, A H; Christensen, M.; Knop, F K; Hartmann, B; Holst, J J; Rosenkilde, M M.

    In: British Journal of Pharmacology, Vol. 173, No. 5, 03.2016, p. 826-838.

    Research output: Contribution to journalJournal article

  45. Published

    Somastostatin restrains the secretion of glucagon-like peptide-1 and 2 (GLP-1 and GLP-2) from isolated perfused porcine ileum. / Hansen, L.; Hartmann, Bolette; Bisgaard, T.; Mineo, H.; Jørgensen, P.N.; Holst, J.J.

    In: Am. J. Physiol., No. 278, 2000, p. E1010-E1018.

    Research output: Contribution to journalJournal article

  46. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells. / Hansen, L.; Deacon, C.F.; Ørskov, C.; Holst, J.J.

    In: Endokrinologiya, No. 140, 1999, p. 5356-5363.

    Research output: Contribution to journalJournal article

  47. Published

    Glucagon-like peptide- 1 secretion is influenced by perfusate glucose concentration and a feedback mechanism involving somatostatin in isolated perfused porcine ileum. / Hansen, L.; Hartmann, B.; Mineo, H.; Holst, J.J.

    In: Regul. Pept., No. 118, 2004, p. 11-18.

    Research output: Contribution to journalJournal article

  48. Published

    Neural regulation of glucagon-like peptide- 1 secretion in pigs. / Hansen, L.; Lampert, S.; Mineo, H.; Holst, J.J.

    In: Am. J. Physiol., No. 287, 2004, p. E939-E947.

    Research output: Contribution to journalJournal article

  49. Published

    The role of glucagon-like peptide 1 for the postprandial effects of metformin in type 2 diabetes : [Meeting Abstract]. / Hansen, L. S.; Gasbjerg, Lærke Smidt; Bronden, A.; Dalsgaard, N. B.; Bahne, E.; Stensen, S.; Hellmann, P. H.; Rehfeld, J.; Holst, J. J.; Vilsboll, T.; Knop, F. K.

    In: Diabetologia, Vol. 62, No. Supl. 1/SI, 110, 09.2019, p. S57-S58.

    Research output: Contribution to journalConference article

  50. Published

    Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists. / Hansen, L. S.; Sparre-Ulrich, A. H.; Svendsen, B.; Christensen, M.; Hartmann, B.; Knop, F. K.; Holst, J. J.; Rosenkilde, M. M.

    In: Diabetologia, Vol. 58, No. 1 supplement, 569, 09.2015, p. S276-S277.

    Research output: Contribution to journalConference abstract in journal

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