Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

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  1. Published

    Quality-by-design in nanomedicine: Highly systematic optimization of lipid-polymer hybrid nanoparticles for efficacious and safe intracellular delivery of cargo siRNA. / Zeng, Xianghui; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Abstract from 2nd Gazi Pharma Symposium Series, Ankara, Turkey.

    Research output: Contribution to conference › Conference abstract for conference › Research

  2. Published

    Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach. / Thanki, Kaushik; Zeng, Xianghui; Justesen, Sarah; Tejlmann, Sarah; Falkenberg, Emily; Van Driessche, Elize; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 120, 11.2017, p. 22-33.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs. / Thanki, Kaushik; Zeng, Xianghui; Justesen, Sarah; Tejlmann, Sarah; Falkenberg, Emily; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Poster session presented at 6th FIP Pharmaceutical Sciences World Congress (PSWC), Stockholm, Sweden.

    Research output: Contribution to conference › Poster › Research

  4. Published

    Lysine-Based α-peptide/β-peptoid peptidomimetics : Influence of hydrophobicity, fluorination and distribution of cationic charge on antimicrobial activity and cytotoxicity. / Molchanova, Natalia; Hansen, Paul Robert; Damborg, Peter Panduro; Nielsen, Hanne Mørck; Franzyk, Henrik.

    In: ChemMedChem, Vol. 12, 2017, p. 312-318.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Innovative Methods and Applications in Mucoadhesion Research. / Mackie, Alan R; Goycoolea, Francisco M; Menchicchi, Bianca; Caramella, Carla Marcella; Saporito, Francesca; Lee, Seunghwan; Stephansen, Karen; Chronakis, Ioannis S; Hiorth, Marianne; Adamczak, Malgorzata; Waldner, Max; Nielsen, Hanne Mørck; Marcelloni, Luciano.

    In: Macromolecular Bioscience, Vol. 17, No. 8, 1600534, 08.2017.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    The impact of particle preparation methods and polymorphic stability of lipid excipients on protein distribution in microparticles. / Liu, Jingying; Christophersen, Philip C; Yang, Mingshi; Nielsen, Hanne M; Mu, Huiling.

    In: Drug Development and Industrial Pharmacy, Vol. 43, No. 12, 12.2017, p. 2032-2042.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Assessment of mucoadhesion using small deformation rheology revisited. / Harloff-Helleberg, Stine; Vissing, Karina Juul; Nielsen, Hanne Mørck.

    In: Nordic Rheology Society Annual Transactions, Vol. 25, 04.2017, p. 63.

    Research output: Contribution to journal › Conference article › Research › peer-review

  8. Published

    Animal models for evaluation of oral delivery of biopharmaceuticals. / Harloff-Helleberg, Stine; Nielsen, Line Hagner; Nielsen, Hanne Mørck.

    In: Journal of Controlled Release, Vol. 268, 12.2017, p. 57-71.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA. / Foged, Camilla (Inventor); Franzyk, Henrik (Inventor); Zeng, Xianghui (Inventor); Nielsen, Hanne Mørck (Inventor); Thanki, Kaushik (Inventor).

    IPC No.: A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00. Patent No.: WO2017158093-A1. Mar 16, 2017.

    Research output: Patent

  10. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy. / Falkenberg, Emily; de Groot, Anne Marit; Sijts, Alice J A M; Thanki, Kaushik; Zeng, Xianghui; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Poster session presented at 10th European Workshop on Particulate Systems (EWPS), Copenhagen, Denmark.

    Research output: Contribution to conference › Poster › Research

  11. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability. / Birch, Ditlev; Christensen, Malene Vinther; Stærk, Dan; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: B B A - Biomembranes, Vol. 1859, No. 12, 2017, p. 2483-2494.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    An approach to identify clinically relevan, non-toxic peptide-antimicrobial combinations that eliminate intrinsic resistance in Gram-negative pathogens. / Baker, Kristin Renee; Jana, Bimal; Nielsen, Hanne Mørck; Franzyk, Henrik; Guardabassi, Luca.

    2017. Abstract from ASM Microbe 2017, New Orleans, United States.

    Research output: Contribution to conference › Conference abstract for conference › Research

ID: 1299091