Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. 2010
  2. Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations. / Jensen, Linda Boye; Mortensen, Kell; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Jensen, Ditte K.; Gadzhyeva, Veronika; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Biomacromolecules, Vol. 11, No. 12, 2010, p. 3571-3577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery. / Cun, Dongmei; Foged, Camilla; Yang, Mingshi; Frøkjær, Sven; Nielsen, Hanne Mørck.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 70-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery. / Cun, Dongmei; Foged, Camilla; Yang, Mingshi; Frøkjær, Sven; Nielsen, Hanne Mørck.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 70-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. / Jensen, Ditte Marie Krohn; Cun, Dongmei; Maltesen, Morten Jonas; Frøkjær, Sven; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 142, 2010, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation. / Jensen, Ditte Marie Krohn; Cun, Dongmei; Maltesen, Morten Jonas; Frøkjær, Sven; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 142, 2010, p. 138-145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23-24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Drug Discovery Today, Vol. 15, No. 23-24, 2010, p. 1109.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Studies towards improved stability and permeability of a cell-penetrating peptide. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Peptide Science, Vol. 16, 2010, p. 148.

    Research output: Contribution to journalConference abstract in journalResearch

  10. Published

    Studies towards improved stability and permeability of a cell-penetrating peptide. / Dahlqvist Clausen, Jacob Andreas; Linderoth, L.; Andersen, R. B.; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Journal of Peptide Science, Vol. 16, 2010, p. 148.

    Research output: Contribution to journalConference abstract in journalResearch

  11. Published

    The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik Ilsø; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 104, No. 6, 2010, p. 1166-1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. / Johansen, Torben Seested; Nielsen, Hanne Mørck; Christensen, Erik Ilsø; Appa, Rupa S.

    In: Thrombosis and Haemostasis, Vol. 104, No. 6, 2010, p. 1166-1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2009
  14. Published

    In Vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum. / Madsen, Henriette Baun; Ifversen, Peter; Madsen, Flemming; Larsen, Birger Brodin; Hausser, Ingrid; Nielsen, Hanne Mørck.

    In: The AAPS Journal, Vol. 11, No. 4, 2009, p. 728-739.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. In Vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum. / Madsen, Henriette Baun; Ifversen, Peter; Madsen, Flemming; Larsen, Birger Brodin; Hausser, Ingrid; Nielsen, Hanne Mørck.

    In: The AAPS Journal, Vol. 11, No. 4, 2009, p. 728-739.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Biotechnology-based pharmaceuticals. / Jørgensen, Lene; Nielsen, Hanne Mørck; Frøkjær, Sven.

    Modern pharmaceutics: applications and advances. ed. / Alexander T. Florence; Juergen Siepmann. Vol. 2 5. ed. New York : Informa Healthcare, 2009. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  17. Biotechnology-based pharmaceuticals. / Jørgensen, Lene; Nielsen, Hanne Mørck; Frøkjær, Sven.

    Modern pharmaceutics: applications and advances. ed. / Alexander T. Florence; Juergen Siepmann. Vol. 2 5. ed. New York : Informa Healthcare, 2009. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  18. Published

    Delivery technologies for biopharmaceuticals : Peptides, proteins, nucleic acids and vaccines. / Jørgensen, Lene; Nielsen, Hanne Mørck.

    Wiley, 2009. 413 p.

    Research output: Book/ReportBookResearchpeer-review

  19. Delivery technologies for biopharmaceuticals : Peptides, proteins, nucleic acids and vaccines. / Jørgensen, Lene; Nielsen, Hanne Mørck.

    Wiley, 2009. 413 p.

    Research output: Book/ReportBookResearchpeer-review

  20. Published

    Innovativt nanopartikeldesign bag skræddersyede vacciner. / Nordly, Pernille Juul; Agger, Else Marie; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2009, p. 19-21.

    Research output: Contribution to journalJournal articleResearch

  21. Innovativt nanopartikeldesign bag skræddersyede vacciner. / Nordly, Pernille Juul; Agger, Else Marie; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2009, p. 19-21.

    Research output: Contribution to journalJournal articleResearch

  22. Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators. / Nordly, Pernille Juul; Madsen, Henriette Baun; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 6, No. 7, 2009, p. 1-16.

    Research output: Contribution to journalReviewResearch

  23. Published

    Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators. / Nordly, Pernille Juul; Madsen, Henriette Baun; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Expert Opinion on Drug Delivery, Vol. 6, No. 7, 2009, p. 1-16.

    Research output: Contribution to journalReviewResearch

  24. 2008
  25. Published

    Cell-penetrating peptides for drug delivery across membrane barriers. / Foged, Camilla; Nielsen, Hanne Moerck.

    In: Expert Opinion on Drug Delivery, Vol. 5, No. 1, 2008, p. 105-17.

    Research output: Contribution to journalReviewResearch

  26. Published

    Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras : lessons for the design of new cell-penetrating peptides. / Foged, Camilla; Franzyk, Henrik; Bahrami, Shervin; Frøkjær, Sven; Jaroszewski, Jerzy Witold; Nielsen, Hanne Mørck; Olsen, Christian Adam.

    In: BBA General Subjects, Vol. 1778, No. 11, 2008, p. 2487-2495.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  28. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  29. Metabolic cleavage and translocation efficiency of selected cell penetrating peptides : A comparative study with epithelial cell cultures. / Foerg, Christina; Weller, Kathrin M.; Rechsteiner, Helene; Nielsen, Hanne Mørck; Fernandez-Carneado, Jimena; Brunisholz, Rene; Giralt, Ernest; Merkle, Hans P.

    In: The AAPS Journal, Vol. 10, No. 2, 2008, p. 349-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Metabolic cleavage and translocation efficiency of selected cell penetrating peptides : A comparative study with epithelial cell cultures. / Foerg, Christina; Weller, Kathrin M.; Rechsteiner, Helene; Nielsen, Hanne Mørck; Fernandez-Carneado, Jimena; Brunisholz, Rene; Giralt, Ernest; Merkle, Hans P.

    In: The AAPS Journal, Vol. 10, No. 2, 2008, p. 349-359.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01. / Christensen, Dennis; Allesø, Morten; Rosenkrands, Ida; Rantanen, Jukka Tapio; Foged, Camilla; Agger, Else Marie; Andersen, Peter; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, No. 3, 2008, p. 914-920.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01. / Christensen, Dennis; Allesø, Morten; Rosenkrands, Ida; Rantanen, Jukka Tapio; Foged, Camilla; Agger, Else Marie; Andersen, Peter; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, No. 3, 2008, p. 914-920.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Polymeric nanocarriers for siRNA delivery : challenges and future prospects. / Cun, Dongmei; Jensen, Linda Boye; Nielsen, Hanne Mørck; Moghimi, Seyed Moien; Foged, Camilla.

    In: Journal of Biomedical Nanotechnology, Vol. 4, No. 3, 2008, p. 258-275.

    Research output: Contribution to journalReviewResearch

  34. Polymeric nanocarriers for siRNA delivery : challenges and future prospects. / Cun, Dongmei; Jensen, Linda Boye; Nielsen, Hanne Mørck; Moghimi, Seyed Moien; Foged, Camilla.

    In: Journal of Biomedical Nanotechnology, Vol. 4, No. 3, 2008, p. 258-275.

    Research output: Contribution to journalReviewResearch

  35. Published

    a, a´- trehalose 6,6´- dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying. / Christensen, Dennis; Kirby, Daniel; Foged, Camilla; Agger, Else Marie; Andersen, Peter; Perrie, Yvonne; Nielsen, Hanne Mørck.

    In: Biochimica et Biophysica Acta - Biomembranes, Vol. 1778, No. 5, 2008, p. 1365-1373.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2007
  37. Published

    Farvel til sprøjten : udvikling af vaccineplaster med nanopartikler. / Madsen, Henriette Baun; Ifversen, Peter; Madsen, Flemming; Manniche, Søren; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 2007, p. 12-13.

    Research output: Contribution to journalJournal articleCommunication

  38. Farvel til sprøjten : udvikling af vaccineplaster med nanopartikler. / Madsen, Henriette Baun; Ifversen, Peter; Madsen, Flemming; Manniche, Søren; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 2007, p. 12-13.

    Research output: Contribution to journalJournal articleCommunication

  39. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test. / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Internation Journal of Pharmaceutics, Vol. 331, No. 2, 2007, p. 160-166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test. / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Internation Journal of Pharmaceutics, Vol. 331, No. 2, 2007, p. 160-166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Journal of Liposome Research, Vol. 17, No. 3-4, 2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA). / Foged, Camilla; Nielsen, Hanne Mørck; Frøkjær, Sven.

    In: Journal of Liposome Research, Vol. 17, No. 3-4, 2007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Trehalose preserves DDA/TDB liposomes and their adjuvant effect during freeze-drying. / Christensen, Dennis; Foged, Camilla; Rosenkrands, Ida; Nielsen, Hanne Mørck; Andersen, Peter; Agger, Else Marie.

    In: BBA General Subjects, Vol. 1768, No. 9, 2007, p. 2120-2129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2004
  45. Published

    Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and Tat(47-57) through well-differentiated epithelial models. / Tréhin, Rachel; Krauss, Ulrike; Beck-Sickinger, Annette G; Merkle, Hans P; Nielsen, Hanne Mørck.

    In: Pharmaceutical Research, Vol. 21, No. 7, 2004, p. 1248-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effect of oil-in-water emulsions on 5-aminolevulinic acid uptake and metabolism to PpIX in cultured MCF-7 cells. / Nielsen, Hanne Mørck; Aemisegger, Caroline; Burmeister, Gerd; Schuchter, Ursula; Gander, Bruno.

    In: Pharmaceutical Research, Vol. 21, No. 12, 2004, p. 2253-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate. / Eirheim, Heidi Ugelstad; Bundgaard, Christoffer; Nielsen, Hanne Mørck.

    In: Toxicology in Vitro, Vol. 18, No. 5, 2004, p. 649-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Metabolic cleavage of cell-penetrating peptides in contact with epithelial models : human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58). / Tréhin, Rachel; Nielsen, Hanne Mørck; Jahnke, Heinz-Georg; Krauss, Ulrike; Beck-Sickinger, Annette G.; Merkle, Hans P.

    In: Biochemical Journal, Vol. 382, No. Pt 3, 2004, p. 945-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2002
  50. Published

    Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro : effect of pH and concentration. / Nielsen, Hanne Mørck; Rassing, Margrethe Rømer.

    In: European Journal of Pharmaceutical Sciences, Vol. 16, No. 3, 2002, p. 151-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium. / Portero, Ana; Remuñán-López, Carmen; Nielsen, Hanne Mørck.

    In: Pharmaceutical Research, Vol. 19, No. 2, 2002, p. 169-74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2000
  53. Published

    TR146 cells grown on filters as a model of human buccal epithelium : IV. Permeability of water, mannitol, testosterone and beta-adrenoceptor antagonists. Comparison to human, monkey and porcine buccal mucosa. / Nielsen, H M; Rassing, M R; Nielsen, Hanne Mørck.

    In: International Journal of Pharmaceutics, Vol. 194, No. 2, 2000, p. 155-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    TR146 cells grown on filters as a model of human buccal epithelium : V. Enzyme activity of the TR146 cell culture model, human buccal epithelium and porcine buccal epithelium, and permeability of leu-enkephalin. / Mørck Nielsen, H; Rømer Rassing, M; Nielsen, Hanne Mørck.

    In: International Journal of Pharmaceutics, Vol. 200, No. 2, 2000, p. 261-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 1999
  56. Published

    TR146 cells grown on filters as a model of human buccal epithelium : III. Permeability enhancement by different pH values, different osmolality values, and bile salts. / Nielsen, Hanne Mørck; Rassing, M R.

    In: International Journal of Pharmaceutics, Vol. 185, No. 2, 1999, p. 215-25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    TR146 cells grown on filters as a model of human buccal epithelium : permeability of fluorescein isothiocyanate-labelled dextrans in the presence of sodium glycocholate. / Nielsen, Hanne Mørck; Verhoef, J C; Ponec, M; Rassing, M R.

    In: Journal of Controlled Release, Vol. 60, No. 2-3, 1999, p. 223-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 1996
  59. Drug delivery studies in Caco-2 monolayers. IV. Ethyl glycoside esters as a novel type of absorption enhancers. / Nielsen, Hanne Mørck; Brøndsted, H.; Frøkjær, Sven; Hovgaard, Lars.

    In: STP pharma sciences, 1996, p. 157-161.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Drug delivery studies in Caco-2 monolayers. IV. Ethyl glycoside esters as a novel type of absorption enhancers. / Nielsen, Hanne Mørck; Brøndsted, H. ; Frøkjær, Sven; Hovgaard, Lars.

    In: STP pharma sciences, 1996, p. 157-161.

    Research output: Contribution to journalJournal articleResearchpeer-review

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