Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor


  1. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K. ; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 669-682.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Conjugation of a cell-penetrating peptide to parathyroid hormone affects its structure, potency, and transepithelial permeation. / Kristensen, Mie; de Groot, Anne Marit; Berthelsen, Jens; Franzyk, Henrik; Sijts, Alice; Nielsen, Hanne Mørck.

    In: Bioconjugate Chemistry, Vol. 26, 2015, p. 477-488.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Corticosteroid solubility and lilpid polarity control release from solid lipid nanoparticles. / Jensen, Louise B.; Magnusson, Emily; Gunnarsson, Linda; Vermehren, Charlotte; Nielsen, Hanne Mørck; Petersson, Karsten.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 53-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Corticosteroid solubility and lilpid polarity control release from solid lipid nanoparticles. / Jensen, Louise B.; Magnusson, Emily; Gunnarsson, Linda; Vermehren, Charlotte; Nielsen, Hanne Mørck; Petersson, Karsten.

    In: Internation Journal of Pharmaceutics, Vol. 390, No. 1, 2010, p. 53-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Cyclodextrins : efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems. / Stojanov, Mladen; Nielsen, Hanne Mørck; Larsen, Kim Lambertsen.

    In: International Journal of Pharmaceutics, Vol. 422, No. 1-2, 2012, p. 349-355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Cyclodextrins : efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems. / Stojanov, Mladen; Nielsen, Hanne Mørck; Larsen, Kim Lambertsen.

    In: International Journal of Pharmaceutics, Vol. 422, No. 1-2, 2012, p. 349-355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius. / Damborg, Peter Panduro; Skindersø, Mette E; Hansen, Paul Robert; Bahnsen, Jesper Søborg; Nielsen, Hanne Mørck; Guardabassi, Luca.

    2012. Poster session presented at 13th Conference of the International Society for Veterinary Epidemiology and Economics (ISVEE XIII), Maastricht, Netherlands.

    Research output: Contribution to conferencePosterResearchpeer-review

  8. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius. / Damborg, Peter Panduro; Skindersø, Mette E; Hansen, Paul Robert; Bahnsen, Jesper Søborg; Nielsen, Hanne Mørck; Guardabassi, Luca.

    2012. Poster session presented at 13th Conference of the International Society for Veterinary Epidemiology and Economics (ISVEE XIII), Maastricht, Netherlands.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration. / Wen, Yanhong; Grøndahl, Lisbeth; Gallego, Monica R.; Jørgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 13, 2012, p. 905-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration. / Wen, Yanhong; Grøndahl, Lisbeth; Gallego, Monica R.; Jørgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 13, 2012, p. 905-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System. / Jing, Xiaona; Foged, Camilla; Martin-Bertelsen, Birte; Yaghmur, Anan; Knapp, Kolja Michael; Malmsten, Martin; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Molecular Pharmaceutics, Vol. 13, No. 6, 06.06.2016, p. 1739-1749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Delivery technologies for biopharmaceuticals : Peptides, proteins, nucleic acids and vaccines. / Jørgensen, Lene; Nielsen, Hanne Mørck.

    Wiley, 2009. 413 p.

    Research output: Book/ReportBookResearchpeer-review

  13. Delivery technologies for biopharmaceuticals : Peptides, proteins, nucleic acids and vaccines. / Jørgensen, Lene; Nielsen, Hanne Mørck.

    Wiley, 2009. 413 p.

    Research output: Book/ReportBookResearchpeer-review

  14. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  15. Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  16. Published

    Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs. / Wen, Yanhong; Gallego, Monica Ramos; Nielsen, Lene Feldskov; Jorgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 85, No. 1, 09.2013, p. 87-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Designing CAF-adjuvanted dry powder vaccines : spray drying preserves the adjuvant activity of CAF01. / Ingvarsson, Pall Thor; Schmidt, Signe Tandrup; Christensen, Dennis; Larsen, Niels Bent; Hinrichs, Wouter Leonardus Joseph; Andersen, Peter; Rantanen, Jukka; Nielsen, Hanne Mørck; Yang, Mingshi; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 167, No. 3, 08.02.2013, p. 256-264.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Development and rheological profiling of biosimilar mucus. / Bøgh, Marie; Baldursdottir, Stefania G.; Nielsen, Maja H.; Müllertz, Anette; Nielsen, Hanne Mørck.

    In: Nordic Rheology Society Annual Transactions, Vol. 21, 2013, p. 233-240.

    Research output: Contribution to journalConference articleResearchpeer-review

  21. Published

    Development and rheological profiling of biosimilar mucus. / Bøgh, Marie; Baldursdottir, Stefania G.; Nielsen, Maja H.; Müllertz, Anette; Nielsen, Hanne Mørck.

    In: Nordic Rheology Society Annual Transactions, Vol. 21, 2013, p. 233-240.

    Research output: Contribution to journalConference articleResearchpeer-review

  22. Drug delivery studies in Caco-2 monolayers. IV. Ethyl glycoside esters as a novel type of absorption enhancers. / Nielsen, Hanne Mørck; Brøndsted, H.; Frøkjær, Sven; Hovgaard, Lars.

    In: STP pharma sciences, 1996, p. 157-161.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Drug delivery studies in Caco-2 monolayers. IV. Ethyl glycoside esters as a novel type of absorption enhancers. / Nielsen, Hanne Mørck; Brøndsted, H. ; Frøkjær, Sven; Hovgaard, Lars.

    In: STP pharma sciences, 1996, p. 157-161.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effect of oil-in-water emulsions on 5-aminolevulinic acid uptake and metabolism to PpIX in cultured MCF-7 cells. / Nielsen, Hanne Mørck; Aemisegger, Caroline; Burmeister, Gerd; Schuchter, Ursula; Gander, Bruno.

    In: Pharmaceutical Research, Vol. 21, No. 12, 2004, p. 2253-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking. / Thanki, Kaushik; Geyer, A.; Zeng, Xianghui; Sami, H.; Gehrig, S. ; Justesen, Sarah; Franzyk, Henrik; Ogris, M.; Nielsen, Hanne Mørck; Foged, Camilla.

    2016. Poster session presented at Annual Meeting of the American Association of Pharmaceutical Sciences (AAPS) 2016, Denver, United States.

    Research output: Contribution to conferencePosterResearch

  26. Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking. / Thanki, Kaushik; Geyer, A.; Zeng, Xianghui; Sami, H.; Gehrig, S.; Justesen, Sarah; Franzyk, Henrik; Ogris, M.; Nielsen, Hanne Mørck; Foged, Camilla.

    2016. Poster session presented at Annual Meeting of the American Association of Pharmaceutical Sciences (AAPS) 2016, Denver, United States.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs. / Thanki, Kaushik; Zeng, Xianghui; Justesen, Sarah; Tejlmann, Sarah; Falkenberg, Emily; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    2017. Poster session presented at 6th FIP Pharmaceutical Sciences World Congress (PSWC), Stockholm, Sweden.

    Research output: Contribution to conferencePosterResearch

  28. Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: Effect of dendrimer charge density. / Jensen, Linda Boye; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Rutherford, Sandra; Danani, Andrea; Nielsen, Hanne Mørck; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 416, 2011, p. 410-418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: Effect of dendrimer charge density. / Jensen, Linda Boye; Pavan, Giovanni M.; Kasimova, Marina Robertovna; Rutherford, Sandra; Danani, Andrea; Nielsen, Hanne Mørck; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 416, 2011, p. 410-418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    End Group Modification : Efficient Tool for Improving Activity of Antimicrobial Peptide Analogues towards Gram-Positive Bacteria. / Jahnsen, Rasmus O; Sandberg-Schaal, Anne; Frimodt-Møller, Niels; Nielsen, Hanne Mørck; Franzyk, Henrik.

    In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Vol. 95, No. Part A, 23.01.2015, p. 40–46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Engineering of an Inhalable DDA/TDB Liposomal Adjuvant : A Quality-by-Design Approach Towards Optimization of the Spray Drying Process. / Ingvarsson, Pall Thor; Yang, Mingshi; Mulvad, Helle; Nielsen, Hanne Mørck; Rantanen, Jukka; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 30, No. 11, 22.06.2013, p. 2772-2784.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach. / Thanki, Kaushik; Zeng, Xianghui; Justesen, Sarah; Tejlmann, Sarah; Falkenberg, Emily; Van Driessche, Elize; Nielsen, Hanne Mørck; Franzyk, Henrik; Foged, Camilla.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 120, 11.2017, p. 22-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Evaluation of carrier-mediated siRNA delivery : lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA. / Colombo, Stefano; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Journal of Controlled Release, Vol. 166, No. 3, 11.01.2013, p. 220-226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate. / Eirheim, Heidi Ugelstad; Bundgaard, Christoffer; Nielsen, Hanne Mørck.

    In: Toxicology in Vitro, Vol. 18, No. 5, 2004, p. 649-57.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium. / Birch, Ditlev; Diedrichsen, Ragna G; Christophersen, Philip C; Mu, Huiling; Nielsen, Hanne M.

    In: European Journal of Pharmaceutical Sciences, Vol. 118, 06.2018, p. 144-153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals. / Harloff-Helleberg, Stine; Fliervoet, Lies A. L.; Fano, Mathias; Schmitt, Mechthild; Antopolski, Maxim; Urtti, Arto; Nielsen, Hanne Morck.

    In: Drug Delivery, Vol. 26, No. 1, 01.01.2019, p. 532-541.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Farvel til sprøjten : udvikling af vaccineplaster med nanopartikler. / Madsen, Henriette Baun; Ifversen, Peter; Madsen, Flemming; Manniche, Søren; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 2007, p. 12-13.

    Research output: Contribution to journalJournal articleCommunication

  38. Farvel til sprøjten : udvikling af vaccineplaster med nanopartikler. / Madsen, Henriette Baun; Ifversen, Peter; Madsen, Flemming; Manniche, Søren; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 2007, p. 12-13.

    Research output: Contribution to journalJournal articleCommunication

  39. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability. / Birch, Ditlev; Christensen, Malene Vinther; Stærk, Dan; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: B B A - Biomembranes, Vol. 1859, No. 12, 2017, p. 2483-2494.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction. / Hedegaard, Sofie Fogh; Derbas, Mohammed Sobhi; Lind, Tania Kjellerup; Kasimova, Marina Robertnova; Christensen, Malene Vinther; Michaelsen, Maria Høtoft; Campbell, Richard A; Jorgensen, Lene; Franzyk, Henrik; Cárdenas, Marité; Nielsen, Hanne Mørck.

    In: Scientific Reports, Vol. 8, No. 1, 6327, 2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Gendannelse af ødelagt væv med stamceller. / Møller, Eva Horn; Wen, Yanhong; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  42. Published

    Gendannelse af ødelagt væv med stamceller. / Møller, Eva Horn; Wen, Yanhong; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  43. Published

    Genetisk nanomedicin til behandling af leddegigt. / Foged, Camilla; Jensen, Linda Boye; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 12.2011, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  44. Genetisk nanomedicin til behandling af leddegigt. / Foged, Camilla; Jensen, Linda Boye; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 12.2011, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  45. Published

    High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles : quality by design optimization and characterization. / Cun, Dongmei; Jensen, Ditte Marie Krohn; Maltesen, Morten Jonas; Bunker, Matthew; Whitside, Paul ; Scurr, David; Foged, Camilla; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 77, No. 1, 2011, p. 26-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles : quality by design optimization and characterization. / Cun, Dongmei; Jensen, Ditte Marie Krohn; Maltesen, Morten Jonas; Bunker, Matthew; Whitside, Paul; Scurr, David; Foged, Camilla; Nielsen, Hanne Mørck.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 77, No. 1, 2011, p. 26-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin. / Water, Jorrit J; Kim, YongTae; Maltesen, Morten J; Franzyk, Henrik; Foged, Camilla; Nielsen, Hanne M.

    In: Pharmaceutical Research, Vol. 32, No. 8, 08.2015, p. 2727-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5. / Kłodzińska, Sylvia N.; Pletzer, Daniel; Rahanjam, Negin; Rades, Thomas; Hancock, Robert E.W.; Nielsen, Hanne M.

    In: Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 20, 102022, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Håb om at ramme latente bakterier i deres skjul. / Bahnsen, Jesper Søborg; Water, Jorrit Jeroen; Foged, Camilla; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning 2012, Vol. 2012, 2012, p. 12-14.

    Research output: Contribution to journalJournal articleResearch

  50. Published

    Håb om at ramme latente bakterier i deres skjul. / Bahnsen, Jesper Søborg; Water, Jorrit Jeroen; Foged, Camilla; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning 2012, Vol. 2012, 2012, p. 12-14.

    Research output: Contribution to journalJournal articleResearch

ID: 1299091